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Current and potential new treatment strategies for creatine deficiency syndromes
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“The brain’s ability to absorb creatine is limited by the blood-brain barrier (BBB) and a lack of SLC6A8 transporters in the astrocyte feet lining the microcapillary endothelial cells [240].”
From Creatine monohydrate supplementation for older adults and clinical populations (2025) · cites this paper as [240]
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“These positive metabolic effects may promote better cognitive functioning during periods of increased ATP demand (sleep deprivation, hypoxia or mental fatigue) or for those who may be reduced brain creatine levels (elderly or those with pathophysiological states such as creatine deficiency syndrome) [240,243–246].”
From Creatine monohydrate supplementation for older adults and clinical populations (2025) · cites this paper as [240]
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Creatine and Creatinine Metabolism
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Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy
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Creatine: Endogenous Metabolite, Dietary, and Therapeutic Supplement
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Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates
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Cited by
Creatine monohydrate supplementation for older adults and clinical populations
Candow, D. G., Ostojic, S. M., Chilibeck, P. D., Longobardi, I., Gualano, B., Tarnopolsky, M. A., Wallimann, T., Moriarty, T., Kreider, R. B., Forbes, S. C., et al. (2025) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2025.2534130 · Cited by 43
Metadata
- Authors
- Fernandes-Pires, G., & Braissant, O.
- Venue
- Molecular Genetics and Metabolism
- Publisher
- Elsevier BV
- Published
- 2022-01
- Volume
- 135
- Issue
- 1
- Pages
- 15-26
- ISSN
- 1096-7192
- Cited by
- 72
- References
- 16
- Language
- en
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- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (31003A-175778)
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- CoChat. (2026). Citation check: Current and potential new treatment strategies for creatine deficiency syndromes. https://app.cochat.ai/papers/10.1016/j.ymgme.2021.12.005
- The paper
- Fernandes-Pires, G., & Braissant, O. (2022). Current and potential new treatment strategies for creatine deficiency syndromes. Molecular Genetics and Metabolism. https://doi.org/10.1016/j.ymgme.2021.12.005
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.