Adenovirus-Associated Defective Virus Particles

THE DEFECTIVENESS OF ROUS SARCOMA VIRUS

Hanafusa, H., Hanafusa, T., & Rubin, H. (1963) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.49.4.572 · Cited by 246 · see citing works

Viruses of Vertebrates

Andrewes, C. H. (1967) · Medical Entomology and Zoology · Cited by 208 · see citing works

Progress in Medical Virology

(1968) · Archives of Disease in Childhood · doi:10.1136/adc.43.229.391 · Cited by 147 · see citing works

Analysis of the defectiveness of Rous sarcoma virus

Hanafusa, H., Hanafusa, T., & Rubin, H. (1964) · Virology · doi:10.1016/0042-6822(64)90081-9 · Cited by 89 · see citing works

Studies on the acridine orange staining of two purified RNA viruses: Poliovirus and tobacco mosaic virus

Mayor, H. D., & Diwan, A. R. (1961) · Virology · doi:10.1016/0042-6822(61)90134-9 · Cited by 70 · see citing works

Investigation of adenovirus antigens by agar gel diffusion techniques

ALLISON, A. C., Pereira, H. G., & Farthing, C. P. (1960) · Virology · doi:10.1016/0042-6822(60)90023-4 · Cited by 39 · see citing works

Antibody in Hepatitis Patients Against a Newly Isolated Virus

O'Malley, J. P., Meyer, H. M., & Smadel, J. E. (1961) · Experimental Biology and Medicine · doi:10.3181/00379727-108-26891 · Cited by 33 · see citing works

A comparison of polyoma, “K”, and Kilham rat viruses with the electron microscope

Dalton, A. J., Kilham, L., & Zeigel, R. F. (1963) · Virology · doi:10.1016/0042-6822(63)90087-4 · Cited by 25 · see citing works

Adenovirus-like Particles from Cancers Induced by Adenovirus-12 but Free of Infectious Virus

Smith, K. O., & Melnick, J. L. (1964) · Science · doi:10.1126/science.145.3637.1190 · Cited by 25 · see citing works

Electron Microscopy of the H-1 Virus. I. Morphology of the Virus and a Possible Virus-Host Relationship 2

Chandra, S., & Toolan, H. W. (1961) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/27.6.1405 · Cited by 21 · see citing works

Further studies on the electron microscopy of the H-1 virus

Toolan, H. W., Saunders, E. L., Greene, E. L., et al. (1964) · Virology · doi:10.1016/0042-6822(64)90016-9 · Cited by 10 · see citing works

Adeno-associated virus vector as a platform for gene therapy delivery

Wang, D., Tai, P. W. L., & Gao, G. (2019) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0012-9 · Cited by 2,444 · see citing works

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Gao, G.-P., Alvira, M. R., Wang, L., Calcedo, R., Johnston, J., & Wilson, J. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182412299 · Cited by 1,520 · see citing works

Viral vector platforms within the gene therapy landscape

Bulcha, J. T., Wang, Y., Ma, H., Tai, P. W. L., & Gao, G. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00487-6 · Cited by 1,404 · see citing works

Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues

Gao, G., Vandenberghe, L. H., Alvira, M. R., Lu, Y., Calcedo, R., Zhou, X., & Wilson, J. M. (2004) · Journal of Virology · doi:10.1128/jvi.78.12.6381-6388.2004 · Cited by 1,070 · see citing works

Immune responses to adenovirus and adeno-associated virus in humans

Chirmule, N., Propert, K. J., Magosin, S. A., Qian, Y., Qian, R., & Wilson, J. M. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300994 · Cited by 684 · see citing works

AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer

Costa Verdera, H., Kuranda, K., & Mingozzi, F. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2019.12.010 · Cited by 641 · see citing works

Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy

Duan, D. (2018) · Molecular Therapy · doi:10.1016/j.ymthe.2018.07.011 · Cited by 489 · see citing works

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

Nault, J.-C., Datta, S., Imbeaud, S., Franconi, A., Mallet, M., Couchy, G., Letouzé, E., Pilati, C., Verret, B., Blanc, J.-F., et al. (2015) · Nature Genetics · doi:10.1038/ng.3389 · Cited by 489 · see citing works

Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design

Ogden, P. J., Kelsic, E. D., Sinai, S., & Church, G. M. (2019) · Science · doi:10.1126/science.aaw2900 · Cited by 356 · see citing works

Human Immune Responses to Adeno-Associated Virus (AAV) Vectors

Ronzitti, G., Gross, D.-A., & Mingozzi, F. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00670 · Cited by 357 · see citing works

Pre-existing Anti–Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy

Louis Jeune, V., Joergensen, J. A., Hajjar, R. J., & Weber, T. (2013) · Human Gene Therapy Methods · doi:10.1089/hgtb.2012.243 · Cited by 358 · see citing works

Gene therapy for neurological disorders: progress and prospects

Deverman, B. E., Ravina, B. M., Bankiewicz, K. S., Paul, S. M., & Sah, D. W. Y. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2018.110 · Cited by 306 · see citing works

Immune responses to retinal gene therapy using adeno-associated viral vectors – implications for treatment success and safety

Bucher, K., Rodríguez-Bocanegra, E., Dauletbekov, D., & Fischer, M. D. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100915 · Cited by 242 · see citing works

Basic Biology of Adeno-Associated Virus (AAV) Vectors Used in Gene Therapy

Balakrishnan, B., & Jayandharan, G. (2014) · Current Gene Therapy · doi:10.2174/1566523214666140302193709 · Cited by 225 · see citing works

Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion

Tse, L. V., Klinc, K. A., Madigan, V. J., Castellanos Rivera, R. M., Wells, L. F., Havlik, L. P., Smith, J. K., Agbandje-McKenna, M., & Asokan, A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704766114 · Cited by 210 · see citing works

Mutational analysis of narrow pores at the fivefold symmetry axes of adeno-associated virus type 2 capsids reveals a dual role in genome packaging and activation of phospholipase A2 activity

Bleker, S., Sonntag, F., & Kleinschmidt, J. A. (2005) · Journal of Virology · doi:10.1128/jvi.79.4.2528-2540.2005 · Cited by 200 · see citing works

AAV hybrid serotypes: improved vectors for gene delivery

Choi, V., McCarty, D., & Samulski, R. (2005) · Current Gene Therapy · doi:10.2174/1566523054064968 · Cited by 191 · see citing works

Lessons learned from the clinical development and market authorization of Glybera

Bryant, L. M., Christopher, D. M., Giles, A. R., Hinderer, C., Rodriguez, J. L., Smith, J. B., Traxler, E. A., Tycko, J., Wojno, A. P., & Wilson, J. M. (2013) · Human Gene Therapy Clinical Development · doi:10.1089/humc.2013.087 · Cited by 189 · see citing works

Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery

Nidetz, N. F., McGee, M. C., Tse, L. V., Li, C., Cong, L., Li, Y., & Huang, W. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.107453 · Cited by 174 · see citing works

Adeno-Associated Virus Integration: Virus versus Vector

Smith, R. H. (2008) · Gene Therapy · doi:10.1038/gt.2008.55 · Cited by 178 · see citing works

Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Transfer

Arjomandnejad, M., Dasgupta, I., Flotte, T. R., & Keeler, A. M. (2023) · BioDrugs · doi:10.1007/s40259-023-00585-7 · Cited by 159 · see citing works

Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins

Wistuba, A., Weger, S., Kern, A., & Kleinschmidt, J. A. (1995) · Journal of Virology · doi:10.1128/jvi.69.9.5311-5319.1995 · Cited by 147 · see citing works

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

Hellström, M., Ruitenberg, M. J., Pollett, M. A., Ehlert, E. M. E., Twisk, J., Verhaagen, J., & Harvey, A. R. (2009) · Gene Therapy · doi:10.1038/gt.2008.178 · Cited by 142 · see citing works

Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids

Chamberlain, K., Riyad, J. M., & Weber, T. (2016) · Human Gene Therapy Methods · doi:10.1089/hgtb.2015.140 · Cited by 141 · see citing works

AAV vectors applied to the treatment of CNS disorders: Clinical status and challenges

Kang, L., Jin, S., Wang, J., Lv, Z., Xin, C., Tan, C., Zhao, M., Wang, L., & Liu, J. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.01.067 · Cited by 131 · see citing works

Adeno-associated virus type 2-mediated gene transfer: altered endocytic processing enhances transduction efficiency in murine fibroblasts

Hansen, J., Qing, K., & Srivastava, A. (2001) · Journal of Virology · doi:10.1128/jvi.75.9.4080-4090.2001 · Cited by 129 · see citing works

Journey to the Center of the Cell: Tracing the Path of AAV Transduction

Dhungel, B. P., Bailey, C. G., & Rasko, J. E. J. (2021) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2020.09.010 · Cited by 122 · see citing works

Human Adeno-Associated Virus Type 5 Is Only Distantly Related to Other Known Primate Helper-Dependent Parvoviruses

Bantel-Schaal, U., Delius, H., Schmidt, R., & zur Hausen, H. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.939-947.1999 · Cited by 128 · see citing works

Capsid antibodies to different adeno-associated virus serotypes bind common regions

Gurda, B. L., DiMattia, M. A., Miller, E. B., Bennett, A., McKenna, R., Weichert, W. S., Nelson, C. D., Chen, W.-J., Muzyczka, N., Olson, N. H., et al. (2013) · Journal of Virology · doi:10.1128/jvi.00622-13 · Cited by 127 · see citing works

Methods for Gene Transfer to the Central Nervous System

Kantor, B., Bailey, R. M., Wimberly, K., Kalburgi, S. N., & Gray, S. J. (2014) · Advances in Genetics · doi:10.1016/b978-0-12-800149-3.00003-2 · Cited by 109 · see citing works

High-Throughput <i>In Vitro</i> , <i>Ex Vivo,</i> and <i>In Vivo</i> Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction

Westhaus, A., Cabanes-Creus, M., Rybicki, A., Baltazar, G., Navarro, R. G., Zhu, E., Drouyer, M., Knight, M., Albu, R. F., Ng, B. H., et al. (2020) · Human Gene Therapy · doi:10.1089/hum.2019.264 · Cited by 102 · see citing works

Adeno‐associated virus vectors and hematology

Russell, D. W., & Kay, M. A. (1999) · Blood · doi:10.1182/blood.v94.3.864.415k34_864_874 · Cited by 104 · see citing works

Studies on the relationship between adeno-associated virus type I (AAV-1) and adenoviruses

Casto, B. C., Atchison, R. W., & Hammon, W. M. (1967) · Virology · doi:10.1016/0042-6822(67)90251-6 · Cited by 99 · see citing works

Structural insights into adeno-associated virus serotype 5

Govindasamy, L., DiMattia, M. A., Gurda, B. L., Halder, S., McKenna, R., Chiorini, J. A., Muzyczka, N., Zolotukhin, S., & Agbandje-McKenna, M. (2013) · Journal of Virology · doi:10.1128/jvi.00867-13 · Cited by 95 · see citing works

Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions

Grieger, J. C., Johnson, J. S., Gurda-Whitaker, B., Agbandje-McKenna, M., & Samulski, R. J. (2007) · Journal of Virology · doi:10.1128/jvi.00580-07 · Cited by 83 · see citing works

Adeno-associated virus (AAV) vectors: Rational design strategies for capsid engineering

Lee, E. J., Guenther, C. M., & Suh, J. (2018) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2018.09.004 · Cited by 83 · see citing works

Adeno-associated Virus: A Key to the Human Genome?

Henckaerts, E., & Linden, R. M. (2010) · Future Virology · doi:10.2217/fvl.10.48 · Cited by 71 · see citing works

Vaccines Based on Novel Adeno-Associated Virus Vectors Elicit Aberrant CD8⁺T-Cell Responses in Mice

Lin, J., Zhi, Y., Mays, L., & Wilson, J. M. (2007) · Journal of Virology · doi:10.1128/jvi.01253-07 · Cited by 66 · see citing works

Strategies to circumvent humoral immunity to adeno-associated viral vectors

Tse, L. V., Moller-Tank, S., & Asokan, A. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.1035645 · Cited by 61 · see citing works

Oligonucleotide conjugated multi-functional adeno-associated viruses

Katrekar, D., Moreno, A. M., Chen, G., Worlikar, A., & Mali, P. (2018) · Scientific Reports · doi:10.1038/s41598-018-21742-x · Cited by 57 · see citing works

Circumventing the packaging limit of AAV-mediated gene replacement therapy for neurological disorders

Marrone, L., Marchi, P. M., & Azzouz, M. (2022) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2022.2012148 · Cited by 56 · see citing works

Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

François, A., Bouzelha, M., Lecomte, E., Broucque, F., Penaud-Budloo, M., Adjali, O., Moullier, P., Blouin, V., & Ayuso, E. (2018) · Molecular Therapy - Methods &amp; Clinical Development · doi:10.1016/j.omtm.2018.07.004 · Cited by 50 · see citing works

Rational engineering of a functional CpG-free ITR for AAV gene therapy

Pan, X., Yue, Y., Boftsi, M., Wasala, L. P., Tran, N. T., Zhang, K., Pintel, D. J., Tai, P. W. L., & Duan, D. (2022) · Gene Therapy · doi:10.1038/s41434-021-00296-0 · Cited by 53 · see citing works

Serotype survey of AAV gene delivery via subconjunctival injection in mice

Song, L., Llanga, T., Conatser, L. M., Zaric, V., Gilger, B. C., & Hirsch, M. L. (2018) · Gene Therapy · doi:10.1038/s41434-018-0035-6 · Cited by 50 · see citing works

Novel Combinatorial MicroRNA-Binding Sites in AAV Vectors Synergistically Diminish Antigen Presentation and Transgene Immunity for Efficient and Stable Transduction

Muhuri, M., Zhan, W., Maeda, Y., Li, J., Lotun, A., Chen, J., Sylvia, K., Dasgupta, I., Arjomandnejad, M., Nixon, T., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.674242 · Cited by 50 · see citing works

Designing and optimizing AAV-mediated gene therapy for neurodegenerative diseases: from bench to bedside

Xu, L., Yao, S., Ding, Y. E., Xie, M., Feng, D., Sha, P., Tan, L., Bei, F., & Yao, Y. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05661-2 · Cited by 48 · see citing works

Focused Update on AAV-Based Gene Therapy Clinical Trials for Inherited Retinal Degeneration

Fuller-Carter, P. I., Basiri, H., Harvey, A. R., & Carvalho, L. S. (2020) · BioDrugs · doi:10.1007/s40259-020-00453-8 · Cited by 41 · see citing works

The Ocular Gene Delivery Landscape

Sahu, B., Chug, I., & Khanna, H. (2021) · Biomolecules · doi:10.3390/biom11081135 · Cited by 28 · see citing works

Directed Evolution of AAV Targeting Primate Retina by Intravitreal Injection Identifies R100, a Variant Demonstrating Robust Gene Delivery and Therapeutic Efficacy in Non-Human Primates

Kotterman, M., Beliakoff, G., Croze, R., Vazin, T., Schmitt, C., Szymanski, P., Leong, M., Quezada, M., Holt, J., Barglow, K., et al. (2021) · doi:10.1101/2021.06.24.449775 · Cited by 20 · see citing works

Effects of immunosuppression on circulating adeno-associated virus capsid-specific T cells in humans

Parzych, E. M., Li, H., Yin, X., Liu, Q., Wu, T.-L., Podsakoff, G. M., High, K. A., Levine, M. H., & Ertl, H. C. J. (2013) · Human Gene Therapy · doi:10.1089/hum.2012.246 · Cited by 16 · see citing works

Prevalence of Anti-Adeno-Associated Virus Serotype 9 Antibodies in Adult Patients with Spinal Muscular Atrophy

Stolte, B., Schreiber-Katz, O., Günther, R., Wurster, C. D., Petri, S., Osmanovic, A., Freigang, M., Uzelac, Z., Leo, M., von Velsen, O., et al. (2022) · Human Gene Therapy · doi:10.1089/hum.2022.054 · Cited by 15 · see citing works

On the development of optical peripheral nerve interfaces

Anderson, H., & Weir, R. F. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.245461 · Cited by 14 · see citing works

Prevention and inhibition of adverse humoral immune response to gene therapy mediated by adeno-associated virus (AAV) vector

Meliani, A. (2026) · doi:10.70675/83ee599czfe90z44e6za201z0938409e1748

The relationship between simian virus 40 and mesothelioma

Rivera, Z. S., Strianese, O., Bertino, P., et al. (2008) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0b013e3283018220 · Cited by 30 · see citing works

Commercial Simian Virus Antisera ThatInhibit Virus Replication inPrimary MonkeyKidneyCellCultures

Hughes, J. H. (1981)

Sequence Comparison Between the Haemagglutinin-neuraminidase Genes of Simian, Canine and Human Isolates of Simian Virus 5

Baty, D. U., Southern, J., & Randall, R. E. (1991) · Journal of General Virology · doi:10.1099/0022-1317-72-12-3103 · Cited by 7 · see citing works

Antigenic Relationship Between Human and Simian Rotaviruses

Schoub, B. D., Lecatsas, G., & Prozesky, O. W. (1977) · Journal of Medical Microbiology · doi:10.1099/00222615-10-1-1 · Cited by 38 · see citing works

Affen‐Aidsviren: Übersicht

Brack, M. (1989) · Journal of Veterinary Medicine Series B · doi:10.1111/j.1439-0450.1989.tb00668.x · Cited by 2 · see citing works