Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases

Sahu, Itishri, Haque, A.K.M. Ashiqul, Weidensee, Brian, Weinmann, Petra, Kormann, Michael S.D.·2019·Molecular Therapy

Cites (330)

Items 201–330 of 330

  1. CCDC65 Mutation Causes Primary Ciliary Dyskinesia with Normal Ultrastructure and Hyperkinetic Cilia
    Amjad Horani, Steven L. Brody, Thomas W. Ferkol, David Shoseyov, Mollie G. Wasserman, Asaf Ta‐Shma, Kate S. Wilson, Philip V. Bayly, Israel Amirav, Malena Cohen‐Cymberknoh et al. · 2013 · PLoS ONE
  2. Surfactant protein B deficiency: Antenatal diagnosis and prospective treatment with surfactant replacement
    Aaron Hamvas, Francis Sessions Cole, Daphne E. deMello · 1994 · The Journal of Pediatrics
  3. Cigarette Smoke Exposure Impairs Respiratory Epithelial Ciliogenesis
    Edwin Tamashiro, Guoxiang Xiong, Wilma Terezinha Anselmo‐Lima, James L. Kreindler, James N. Palmer, Noam A. Cohen · 2009 · American Journal of Rhinology and Allergy
  4. Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
    Yazan M. Abbas, Beatrice T. Laudenbach, Saúl Martínez‐Montero, Regina Cencic, Matthias Habjan, Andreas Pichlmair, Masad José Damha, Jerry Pelletier, Bhushan Nagar · 2017 · Proceedings of the National Academy of Sciences
  5. Induction of HIV-1 gag specific immune responses by cationic micelles mediated delivery of gag mRNA
    Zhao, Mengnan, Li, Man, Zhang, Zhirong, Gong, Tao, Sun, Xun · 2016 · Drug Delivery
  6. Malat1 regulates myogenic differentiation and muscle regeneration through modulating MyoD transcriptional activity
    Xiaona Chen, Liangqiang He, Yu Fen Zhao, Yuying Li, Suyang Zhang, Kun Sun, Karl Kam Hei So, Fengyuan Chen, Liang Zhou, Leina Lu et al. · 2017 · Cell Discovery
  7. Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci
    Sima J. Zacharek, Christine F. Brainson, Allison N. Lau, David W. Gludish, Alan Y. Chou, Joshua W. K. Ho, Raffaella Zamponi, Roi Gazit, Christoph Bock, Natalie Jäger et al. · 2011 · Cell stem cell
  8. Small Molecules Block the Polymerization of Z α1-Antitrypsin and Increase the Clearance of Intracellular Aggregates
    Meera Mallya, Russell L. Phillips, Sanjay Adrian Saldanha, Bibek Gooptu, Sarah C. Leigh Brown, Daniel J. Termine, Arash M. Shirvani, Ying Wu, Richard N. Sifers, Ruben A Abagyan et al. · 2007 · Journal of Medicinal Chemistry
  9. Oxidation of Z α1-Antitrypsin by Cigarette Smoke Induces Polymerization
    Sam Alam, Zhenjun Li, Sabina M Janciauskiene, Ravi Mahadeva · 2010 · American Journal of Respiratory Cell and Molecular Biology
  10. The Bearded box, a novel 3′ UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression
    Eric C. Lai, James W. Posakony · 1997 · Development
  11. Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
    Kyle K.L. Phua, Herman F. Staats, Kam W. Leong, Smita K. Nair · 2014 · Scientific Reports
  12. Multifunctional triblock copolymers for intracellular messenger RNA delivery
    Connie Cheng, Anthony J. Convertine, Patrick S. Stayton, James D. Bryers · 2012 · Biomaterials
  13. The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro
    Marc Stern, Natasha J. Caplen, J. A. Browning, Uta Griesenbach D, F Sorgi, Leaf Huang, Dieter C. Gruenert, C Marriot, RG Crystal, Duncan M Geddes et al. · 1998 · Gene Therapy
  14. Ciliary beating is depressed in nasal cilia from chronic obstructive pulmonary disease subjects
    Asma Yaghi, Aisha Zaman, Gerard Cox, MYRNA B. DOLOVICH · 2012 · Respiratory Medicine
  15. Mucus altering agents as adjuncts for nonviral gene transfer to airway epithelium
    Stefano Ferrari, Chris Kitson, R Farley, Rachel M. Steel, C Marriott, DA Parkins, Maurizio Scarpa, Brandon J. Wainwright, MJ Evans, William Henry Colledge et al. · 2001 · Gene Therapy
  16. Specification of ion transport cells in theXenopuslarval skin
    Ian K. Quigley, Jennifer L. Stubbs, Chris R. Kintner · 2011 · Development
  17. A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs
    Karl‐Josef Kallen, Andreas Theß · 2013 · Therapeutic Advances in Vaccines
  18. Airway Epithelium Dysfunction in Cystic Fibrosis and COPD
    Virginia De Rose, Kevin Molloy, Sophie T. Gohy, Charles Pilette, Catherine M. Greene · 2018 · Mediators of Inflammation
  19. The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy
    Heleen Dewitte, Sandra Van Lint, Carlo Heirman, Kris Thielemans, Stefaan C. De Smedt, Karine Breckpot, Ine Lentacker · 2014 · Journal of Controlled Release
  20. Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model
    Shalesh Kaushal, Mani Annamali, Keith Blomenkamp, David A. Rudnick, Donna R. Halloran, Elizabeth M. Brunt, Jeffrey H. Teckman · 2010 · Experimental Biology and Medicine
  21. A protein binding the methylated 5'-terminal sequence, m7GpppN, of eukaryotic messenger RNA.
    Witold Filipowicz, Yasuhiro Furuichi, J M Sierra · 1976 · Proceedings of the National Academy of Sciences
  22. Tissue remodelling in pulmonary fibrosis
    Lars Knudsen, Clemens Ruppert, Matthias Ochs · 2016 · Cell and Tissue Research
  23. MHC Class I Antigen Processing of an Adenovirus CTL Epitope Is Linked to the Levels of Immunoproteasomes in Infected Cells
    Alice J.A.M. Sijts, Sybille Standera, René E. M. Toes, Thomas Ruppert, N. J. C. M. Beekman, Peter A. van Veelen, FERRY A. OSSENDORP, Cornelis J.M. Melief, Peter Michael Kloetzel · 2000 · The Journal of Immunology
  24. Nanoparticles in the lung
    Wolfgang G. Kreyling, Stephanie Hirn, Carsten Schleh · 2010 · Nature Biotechnology
  25. Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism
    Mays, Lauren E., Ammon-Treiber, Susanne, Mothes, Benedikt, Alkhaled, Mohammed, Rottenberger, Jennifer, Müller-Hermelink, Eva Sophie, Grimm, Melanie, Mezger, Markus, Beer-Hammer, Sandra, von Stebut, Esther et al. · 2013 · Journal of Clinical Investigation
  26. LRRC6 Mutation Causes Primary Ciliary Dyskinesia with Dynein Arm Defects
    Amjad Horani, Thomas W. Ferkol, David Shoseyov, Mollie G. Wasserman, Yifat S. Oren, Batsheva Kerem, Israel Amirav, Malena Cohen‐Cymberknoh, Susan K. Dutcher, Steven L. Brody et al. · 2013 · PLoS ONE
  27. Multicenter Trial of Single-Dose Modified Bovine Surfactant Extract (Survanta) for Prevention of Respiratory Distress Syndrome
    Roger F. Soll, Ronald E. Hoekstra, John J.W. Fangman et al. · 1990 · PEDIATRICS
  28. Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles
    Baba, Miyuki, Itaka, Keiji, Kondo, Kenji, Yamasoba, Tatsuya, Kataoka, Kazunori · 2015 · Journal of Controlled Release
  29. Distribution and Elimination of Poly(methyl-2-14C-methacrylate) Nanoparticle Radioactivity after Injection in Rats and Mice
    Jörg Kreuter, U. Täuber, Volker Illi · 1979 · Journal of Pharmaceutical Sciences
  30. Inherited Surfactant Protein-B Deficiency and Surfactant Protein-C Associated Disease: Clinical Features and Evaluation
    Aaron Hamvas · 2006 · Seminars in Perinatology
  31. Role of Hypoxia-Inducible Factor-1α in Hypoxia-Induced Apoptosis of Primary Alveolar Epithelial Type II Cells
    Stefanie Krick, Bastian G. Eul, Jörg Hänze · 2005 · American Journal of Respiratory Cell and Molecular Biology
  32. Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema
    Florie Borel, Huaming Sun, Marina V. Zieger, Andrew Cox, Brynn H. Cardozo, Weiying Li, Gabriella Borba de Oliveira, Airiel M. Davis, Alisha M. Gruntman, Terence R. Flotte et al. · 2018 · Proceedings of the National Academy of Sciences
  33. Control of mRNA stability in eukaryotes
    Sarah Faith Newbury · 2005 · Biochemical Society Transactions
  34. Regeneration of Alveolar Type I and II Cells from Scgb1a1-Expressing Cells following Severe Pulmonary Damage Induced by Bleomycin and Influenza
    Dahai Zheng, Gino Valentino Limmon, Lu Yin, Nicola H. N. Leung, Hanry Yu, Vincent T. K. Chow, Jianzhu Chen · 2012 · PLoS ONE
  35. Surfactant Replacement Therapy at Birth: Final Analysis of a Clinical Trial and Comparisons With Similar Trials
    James W. Kendig, Robert H. Notter, Christopher Cox et al. · 1988 · PEDIATRICS
  36. Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases
    Akitsugu Matsui, Satoshi Uchida, Takehiko Ishii, Keiji Itaka, Kazunori Kataoka · 2015 · Scientific Reports
  37. Properties of Rat Tracheal Epithelial Cells Separated Based on Expression of Cell Surface α -Galactosyl End Groups
    Scott H. Randell, Christine E. Comment, Frans C. S. Ramaekers · 1991 · American Journal of Respiratory Cell and Molecular Biology
  38. Control of mRNA stability in eukaryotes
    Sarah Faith Newbury · 2006 · Biochemical Society Transactions
  39. Inflammation‐associated remodelling and fibrosis in the lung – a process and an end point
    William A. Wallace, Paul M. Fitch, A. John Simpson · 2006 · International Journal of Experimental Pathology
  40. A Concentrated and Stable Aerosol Formulation of Cationic Lipid:DNA Complexes Giving High-Level Gene Expression in Mouse Lung
    Simon J. Eastman, Michael Lukason, Jennifer D. Tousignant · 1997 · Human Gene Therapy
  41. Overexpression of urokinase receptor in mammalian cells following administration of the in vitro transcribed encoding mRNA
    Karikó, K, Kuo, A, Barnathan, E S · 1999 · Gene Therapy
  42. Activation of IFN-β expression by a viral mRNA through RNase L and MDA5
    Priya Luthra, Dengyun Sun, Robert H. Silverman, Biao He · 2011 · Proceedings of the National Academy of Sciences
  43. Bronchiolitis Obliterans Syndrome: Alloimmune-Dependent and -Independent Injury with Aberrant Tissue Remodeling
    Masaaki Sato, Shaf H Keshavjee · 2008 · Seminars in Thoracic and Cardiovascular Surgery
  44. Pharmacological approaches to discovery and development of new mucolytic agents
    Malcolm King, Bruce K. Rubin · 2002 · Advanced Drug Delivery Reviews
  45. Effervescent dry powder for respiratory drug delivery
    Leticia Ely, Wilson Roa, Warren H. Finlay, Raimar Löbenberg · 2006 · European Journal of Pharmaceutics and Biopharmaceutics
  46. Identification of Dynein Heavy Chain 7 as an Inner Arm Component of Human Cilia That Is Synthesized but Not Assembled in a Case of Primary Ciliary Dyskinesia
    Yan J. Zhang, Wanda K. O’Neal, Scott H. Randell, Kevin Blackburn, Mary B. Moyer, Richard C. Boucher, Lawrence E. Ostrowski · 2002 · Journal of Biological Chemistry
  47. Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5
    George E. Katibah, Yidan Qin, David J. Sidote · 2014 · Proceedings of the National Academy of Sciences
  48. Mechanism of development of ionocytes rich in vacuolar-type H+-ATPase in the skin of zebrafish larvae
    Masahiro Esaki, Kazuyuki Hoshijima, Nobuhiro Nakamura, Keijiro Munakata, Mikiko Tanaka, Kayoko Ookata, Kazuhide Asakawa, Koichi Kawakami, Weiyi Wang, Eric S. Weinberg et al. · 2009 · Developmental Biology
  49. Evaluation of nanoparticles as drug-delivery systems. III: materials, stability, toxicity, possibilities of targeting, and use.
    J Kreuter · 1983 · PubMed
  50. Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery
    Jiahe Li, Wade Wang, Yanpu He, Yingzhong Li, Emily Z. Yan, Ketian Zhang, Darrell J. Irvine, Paula Therese Hammond · 2017 · ACS Nano
  51. Directed Migration of Pulmonary Neuroendocrine Cells toward Airway Branches Organizes the Stereotypic Location of Neuroepithelial Bodies
    Masafumi Noguchi, Kenta Sumiyama, Mitsuru Morimoto · 2015 · Cell Reports
  52. Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis
    Haque, A. K. M. Ashiqul, Dewerth, Alexander, Antony, Justin S., Riethmüller, Joachim, Schweizer, Georg R., Weinmann, Petra, Latifi, Ngadhnjim, Yasar, Hanzey, Pedemonte, Nicoletta, Sondo, Elvira et al. · 2018 · Scientific Reports
  53. Biochemical Efficacy and Safety of a New Pooled Human Plasma α1-Antitrypsin, Respitin
    James K. Stoller, Farshid N. Rouhani, Mark Brantly, Seta Shahin, Raed A. Dweik, James M. Stocks, Jack L. Clausen, Edward J. Campbell, Frank L. Norton · 2002 · CHEST Journal
  54. Fibrotic Response of Tissue Remodeling in COPD
    Lina María Salazar-Peláez, Ana Milena Herrera · 2011 · Lung
  55. Cystic fibrosis airway epithelium remodelling: involvement of inflammation
    Damien Adam, Jacqueline Roux-Delrieu, Emilie Luczka · 2014 · The Journal of Pathology
  56. miR-199a-5p Silencing Regulates the Unfolded Protein Response in Chronic Obstructive Pulmonary Disease and α1-Antitrypsin Deficiency
    Tidi Maharani Hassan, Tomás P. Carroll, Patrick G. Buckley · 2013 · American Journal of Respiratory and Critical Care Medicine
  57. Endothelial Nitric Oxide Synthase as a Potential Susceptibility Gene in the Pathogenesis of Emphysema in α 1-Antitrypsin Deficiency
    Alexey Novoradovsky, Mark Brantly, Myron A. Waclawiw et al. · 1999 · American Journal of Respiratory Cell and Molecular Biology
  58. NewDNAH11mutations in primary ciliary dyskinesia with normal axonemal ultrastructure: Fig. 1—
    Massimo Pifferi, Angela Michelucci, M. E. Conidi, Angela Maria Cangiotti, Paolo Simi, P Macchia, Attilio Loris Boner · 2010 · European Respiratory Journal
  59. Interstitial lung disease in children – genetic background and associated phenotypes
    Dominik Hartl, Matthias Griese · 2005 · Respiratory Research
  60. Secretory Hyperresponsiveness and Pulmonary Mucus Hypersecretion
    Bruce K. Rubin, Kostas Ν. Priftis, H. Joel Schmidt, Markus O. Henke · 2014 · CHEST Journal
  61. Cystic fibrosis transmembrane conductance regulator‐mRNA delivery: a novel alternative for cystic fibrosis gene therapy
    Nadine Bangel‐Ruland, Katja Tomczak, Elena Fernández Fernández, Geraldine Leier, Barbara Leciejewski, Carsten Rudolph, Joseph Rosenecker, Wolf‐Michael Weber · 2013 · The Journal of Gene Medicine
  62. SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency
    Connolly, Brendan, Isaacs, Cleo, Cheng, Lei, Asrani, Kirtika H., Subramanian, Romesh R. · 2018 · Journal of Nucleic Acids
  63. Targeted High Lung Concentrations of Itraconazole Using Nebulized Dispersions in a Murine Model
    Jason T. McConville, Kirk A. Overhoff, Prapasri Sinswat, Jason M. Vaughn, Bradi L. Frei, David S. Burgess, Robert L. Talbert, Jay I. Peters, Keith P. Johnston, Robert O. Williams · 2006 · Pharmaceutical Research
  64. Smooth Muscle Isoactin and Elastin in Fetal Bovine Lung
    Akihiko Noguchi, Rajkumar Reddy, Jonathan D. Kursar, William C. Parks, Robert P. Mecham · 1989 · Experimental Lung Research
  65. Comprehensive study of the drug delivery properties of poly( l -lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice
    Vladimir Shalgunov, Daria Zaytseva‐Zotova, Arkadi Zintchenko, Tatiana Levada, Yuri Shilov, Dmitry Andreyev, Dzhangar Dzhumashev, Evgeny Metelkin, Alexandra Urusova, Oleg O Demin et al. · 2017 · Journal of Controlled Release
  66. Reflex regulation of airway sympathetic nerves in guinea‐pigs
    Eun Joo Oh, Stuart B. Mazzone, Brendan James Canning · 2006 · The Journal of Physiology
  67. Actin limits enhancement of nanoparticle diffusion through cystic fibrosis sputum by mucolytics
    Victoria J. Broughton-Head, James Richard Smith, Jagdeep Shur · 2006 · Pulmonary Pharmacology & Therapeutics
  68. Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus
    Niek N. Sanders, Stefaan C. De Smedt, SH Cheng · 2002 · Gene Therapy
  69. The cellular and molecular determinants of emphysematous destruction in COPD
    Masaru Suzuki, Marc A. Sze, J. Campbell, John F. Ii Brothers, M. Lenburg, J. McDonough, W. Elliott, J. Cooper, A. Spira, J. Hogg · 2017 · Scientific Reports
  70. Optimized transfection of mRNA transcribed from a d(A/T)100 tail-containing vector
    Narayanasamy Elango, Suratha Elango, Pooja Shivshankar, Michael S. Katz · 2005 · Biochemical and Biophysical Research Communications
  71. Antisense oligonucleotide eluforsen improves CFTR function in F508del cystic fibrosis
    Isabelle Sermet‐Gaudelus, John Paul Clancy, David P. Nichols, Jerry A. Nick, K. De Boeck, George Marty Solomon, Marcus Alexander Mall, James A. Bolognese, Florilène Bouisset, Wilhelmina den Hollander et al. · 2018 · Journal of Cystic Fibrosis
  72. Adenoviral-Mediated Gene Transfer of Human Surfactant Protein B to Respiratory Epithelial Cells
    S Yei, Cindy J. Bachurski, Timothy E. Weaver · 1994 · American Journal of Respiratory Cell and Molecular Biology
  73. Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro
    Dahai Zheng, Boon-Seng Soh, Lu Yin, Guangan Hu, Qingfeng Chen, Hyungwon Choi, Jongyoon Han, Vincent T. K. Chow, Jianzhu Chen · 2017 · Scientific Reports
  74. Pulmonary neuroepithelial bodies are polymodal airway sensors: Evidence for CO2/H+sensing
    S. S. A. Livermore, Y. Zhou, Jingyi Pan · 2015 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  75. Persistent Lung Disease in Adults with NKX2.1 Mutation and Familial Neuroendocrine Cell Hyperplasia of Infancy
    Rebekah J. Nevel, Errine T. Garnett, John A. Worrell · 2016 · Annals of the American Thoracic Society
  76. The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency
    Alice M. Wood, Matthew J. Simmonds, D Bayley · 2008 · Respiratory Research
  77. Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications
    Tatjana Michel, Daniel Luft, Meike-Kristin Abraham, Sabrina Reinhardt, Martha L. Salinas Medina, Julia Kurz, Martin Schaller, Meltem Avci‐Adali, Christian Schlensak, Karlheinz Peter et al. · 2017 · Molecular Therapy — Nucleic Acids
  78. Mucin Production during Prenatal and Postnatal Murine Lung Development
    Michelle G. Roy, Mahdis Rahmani, Jesus R. Hernandez, Samantha Alexander, Camille Ehré, Samuel B. Ho, Christopher M. Evans · 2011 · American Journal of Respiratory Cell and Molecular Biology
  79. Enhancement of Dendrimer-Mediated Transfection Using Synthetic Lung Surfactant Exosurf Neonatal in Vitro
    Jolanta F. Kukowska‐Latallo, Chunling Chen, Jonathan D. Eichman · 1999 · Biochemical and Biophysical Research Communications
  80. Lsm proteins bind and stabilize RNAs containing 5′ poly(A) tracts
    Naomi Bergman, Karen C. M. Moraes, John R Anderson, Božidarka L. Zarić, Christian Kambach, Robert J. Schneider, Carol J. Wilusz, Jeffrey Wilusz · 2007 · Nature Structural & Molecular Biology
  81. Association of IREB2 and CHRNA3polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
    Woo Jin Kim, Alice M. Wood, Alan F. Barker, Mark Brantly, Edward J. Campbell, Edward Eden, Noel Gerard McElvaney, Stephen I. Rennard, Robert A. Sandhaus, James M. Stocks et al. · 2012 · Respiratory Research
  82. Mucin Production during Prenatal and Postnatal Murine Lung Development
    MG Roy, M. Rahmani, J. R. Hernandez, Samantha Alexander, Camille Ehré, Samuel B. Ho, Christopher M. Evans · 2011 · American Journal of Respiratory Cell and Molecular Biology
  83. Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease
    Marı́a J. Chiuchiolo, Ronald G. Crystal · 2016 · Annals of the American Thoracic Society
  84. Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis
    Aisha A. Aslam, Colin Higgins, Ian P Sinha, Kevin W Southern · 2017 · Cochrane Database of Systematic Reviews
  85. Synthetic mRNAs for manipulating cellular phenotypes: an overview
    Elgar Susanne Quabius, Guido Krupp · 2014 · New Biotechnology
  86. Cilia and Models for Studying Structure and Function
    Lawrence E. Ostrowski, Susan K. Dutcher, Cecilia W. Lo · 2011 · Proceedings of the American Thoracic Society
  87. Biophysical determinants of alveolar epithelial plasma membrane wounding associated with mechanical ventilation
    Omar Hussein, Bruce J. Walters, Randolph W. Stroetz, Paul Valencia, Deborah L. McCall, Rolf D. Hubmayr · 2013 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  88. Airway liquid: a barrier to drug diffusion?
    Widdicombe Jg · 1997 · European Respiratory Journal
  89. A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis
    Eric W.F.W. Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, Alan Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo et al. · 2016 · Efficacy and Mechanism Evaluation
  90. TLR Ignores Methylated RNA?
    Ken J. Ishii, Shizuo Akira · 2005 · Immunity
  91. N-Terminally Extended Surfactant Protein (SP) C Isolated from SP-B-Deficient Children Has Reduced Surface Activity and Inhibited Lipopolysaccharide Binding
    Jing Li, Machiko Ikegami, Cheng-Lun Na · 2004 · Biochemistry
  92. Development of Optimized, Inhalable, Gemcitabine-Loaded Gelatin Nanocarriers for Lung Cancer
    Susanne R. Youngren-Ortiz, David B. Hill, Peter R. Hoffmann, Kenneth R. Morris, Edward G. Barrett, M. Gregory Forest, Mahavir Bhupal Chougule · 2017 · Journal of Aerosol Medicine and Pulmonary Drug Delivery
  93. Activation conditions determine susceptibility of murine primary T-lymphocytes to retroviral infection
    Andrea B. Hagani, Isabelle Rivière, Cuiwen Tan, Anja Krause, Michel Sadelain · 1999 · The Journal of Gene Medicine
  94. Quantitative Analysis of Pulmonary Surfactant Proteins B and C
    Martin van Eijk, C.G.M. de Haas, Henk P. Haagsman · 1995 · Analytical Biochemistry
  95. New Synthetic Surfactants: The Next Generation?
    Robert H. Pfister, Roger F. Soll · 2005 · Neonatology
  96. Decreased glutathione and low catalase activity contribute to oxidative stress in children with α-1 antitrypsin deficiency: Table 1
    Amparo Escribano, Mónica Amor, Sara Pastor, Silvia Castillo, Francisco Sanz, Pilar Codoñer‐Franch, Francisco Dası́ · 2014 · Thorax
  97. Cell mechanics of alveolar epithelial cells (AECs) and macrophages (AMs)
    Sophie Féréol, Rédouane Fodil, Gabriel Pelle, Bruno Louis, Daniel Isabey · 2008 · Respiratory Physiology & Neurobiology
  98. Repair of naphthalene-induced acute tracheal injury by basal cells depends on β-catenin
    Han‐Shui Hsu, Chen‐Chi Liu, Jiun-Han Lin · 2013 · Journal of Thoracic and Cardiovascular Surgery
  99. On the Transport of Lipoplexes Through Cystic Fibrosis Sputum
    Niek N. Sanders, Elsa Van Rompaey, Stefaan C. De Smedt · 2002 · Pharmaceutical Research
  100. Evaluation of danazol therapy for patients with PiZZ alpha-1-antitrypsin deficiency.
    Mark Damian Wewers, J E Gadek, Brendan A. Keogh · 1986 · PubMed
  101. Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants
    Riccardo Ronzoni, Romina Berardelli, Daniela Medicina · 2015 · Human Molecular Genetics
  102. Genetic basis of respiratory distress syndrome
    Mikko Hallman · 2006 · Frontiers in bioscience
  103. Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury
    Frans J. Walther, José M. Hernández-Juviel, Larry M. Gordon, Alan J. Waring · 2014 · PeerJ
  104. Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency
    Cristina Esquinas, Sabina M. Janciauskiene, Ricardo Gonzalo et al. · 2017 · International Journal of COPD
  105. Lipid-Mediated Delivery of Oligonucleotide to Pulmonary Endothelium
    Zheng Ma, Junlan Zhang, Sean M. Alber · 2002 · American Journal of Respiratory Cell and Molecular Biology
  106. Production and characterisation of recombinant forms of human pulmonary surfactant protein C (SP-C): Structure and surface activity
    Dunja Lukovic, Inés Plasencia, Francisco José Taberner · 2006 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  107. Lumacaftor-ivacaftor (Orkambi) for cystic fibrosis: behind the ‘breakthrough’
    Martin G. Mayer · 2015 · BMJ Evidence-Based Medicine
  108. mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo
    Franziska Zeyer, Benedikt Mothes, Clara Will, Melanie Carevic, Jennifer Rottenberger, Bernd Nürnberg, Dominik Hartl, Rupert Handgretinger, Sandra Beer‐Hammer, Michael Kormann · 2016 · PLoS ONE
  109. A novel RNA molecular signature for activation of 2′-5′ oligoadenylate synthetase-1
    Virginia K. Vachon, Brenda M. Calderon, Graeme L. Conn · 2014 · Nucleic Acids Research
  110. Anticodon shift in tRNA: a novel mechanism in missense and nonsense suppression.
    Emanuel J. Murgola, Norman E. Prather, Betsy H. Mims · 1983 · Proceedings of the National Academy of Sciences
  111. Phase I/II Study of Intrapleural Administration of a Serotype rh.10 Replication-Deficient Adeno-Associated Virus Gene Transfer Vector Expressing the Human α1-Antitrypsin cDNA to Individuals with α1-Antitrypsin Deficiency
    Marı́a J. Chiuchiolo, Stephen M. Kaminsky, Dolan Sondhi, Denesy Mancenido, Charleen Hollmann, Ronald G. Crystal · 2014 · Human Gene Therapy Clinical Development
  112. Assessment of the Efficacy of In Vivo CFTR Protein Replacement Therapy in CF Mice
    Mohabir Ramjeesingh, Ling‐Jun Huan, Michael A. Wilschanski et al. · 1998 · Human Gene Therapy
  113. Accelerated telomere attrition in children and teenagers with α1-antitrypsin deficiency
    Amparo Escribano, Sara Pastor, Ana Reula, Silvia Castillo, Silvia Alfambra Vicente, Francisco Sanz, Francisco Casas Maldonado, María Torres, Estrella Fernández‐Fabrellas, Pilar Codoñer‐Franch et al. · 2016 · European Respiratory Journal
  114. Featured Article: Electroporation-mediated gene delivery of surfactant protein B (SP-B) restores expression and improves survival in mouse model of SP-B deficiency
    Rebecca C Barnett, Xin Lin, Michael Barravecchia, Rosemary Norman, Karen L. de Mesy Bentley, Fabeha Fazal, Jennifer L. Young, David A. Dean · 2017 · Experimental Biology and Medicine
  115. Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies
    Justin S. Antony, Alexander Dewerth, Ashiqul Haque, Rupert Handgretinger, Michael Kormann · 2015 · Molecular and Cellular Pediatrics
  116. In Vitro Evaluation of a Novel mRNA-Based Therapeutic Strategy for the Treatment of Patients Suffering from Alpha-1-Antitrypsin Deficiency
    Tatjana Michel, Anna Kankura, Martha L. Salinas Medina, Julia Kurz, Andreas Behring, Meltem Avci‐Adali, Andrea Nolte, Christian Schlensak, Hans Peter Wendel, Stefanie Krajewski · 2015 · Nucleic Acid Therapeutics
  117. Neutrophil elastase-induced elastin degradation mediates macrophage influx and lung injury in 60% O2-exposed neonatal rats
    Azhar Masood, Man Yi, Rosetta Belcastro · 2015 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  118. Stem Cells and Lung Regeneration
    M Elbadrawy, Nesrein M. Shalabi, Mie A. Mohamed, Amany Ragab, Heba Wagih Abdelwahab · 2016 · International Journal of Stem Cells
  119. Preparation and characterization of lung-targeting ceftiofur-loaded gelatin microspheres
    Zhihui Hao, Baohan Qü, Yanling Wang · 2011 · Drug Development and Industrial Pharmacy
  120. Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis
    Aisha A. Aslam, Nikki Jahnke, Tracey Remmington · 2017 · Paediatric Respiratory Reviews
  121. A Sense of Self: RIG-I’s Tolerance to Host RNA
    John W. Schoggins · 2015 · Immunity
  122. Cross-Talk between Epithelial Cells and Type 2 Immune Signaling: The Role of IL-25
    Erin D. Gordon, Richard M. Locksley, John V. Fahy · 2016 · American Journal of Respiratory and Critical Care Medicine
  123. Novel Treatment Strategies for Liver Disease Due to a1‐Antitrypsin Deficiency
    N.M. Maurice, David H. Perlmutter · 2012 · Clinical and Translational Science
  124. Epigenetics and the Unfolded Protein Response in the Lung: Emerging Role for MicroRNAs
    Serge Patrick Nana-Sinkam, Augustine M.K. Choi · 2014 · American Journal of Respiratory and Critical Care Medicine
  125. Alpha1-Antitrypsin Augmentation Therapy
    Robert A. Sandhaus · 1993 · Birkhäuser Basel eBooks
  126. Special Issue: Gene Therapy with Emphasis on RNA Interference
    Kenneth H. Lundstrom · 2015 · Viruses
  127. Transient Gene Expression in Tobacco using Gibson Assembly and the Gene Gun
    Matthew D. Mattozzi, Mathias J.E.E.E. Voges, Pamela A. Silver, Jeffrey C. Way · 2014 · Journal of Visualized Experiments
  128. Vitamin E and liver damage in MZ heterozygous infants with alpha1‐antitrypsin deficiency
    Klaus Pittschieler · 1993 · Acta Paediatrica
  129. Oxidative Stress and Polymorphism of Xenobiotic-Metabolizing Enzymes in Two Patients with Severe Alpha-1-Antitrypsin Deficiency
    Aleksandra Topić, Ljudmila M. Nagorni-Obradović, Djordje D. Francuski · 2016 · Biochemical Genetics
  130. Expression of mRNAs Microinjected Into Somatic Cells
    Julio E. Celis · 1984 · Novartis Foundation symposium