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Cited by 414

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Endosonography-guided fine needle aspiration biopsy in the evaluation of pancreatic masses

Harewood, G·2002·The American Journal of Gastroenterology

Abstract

OBJECTIVES: Diagnosis of pancreatic tumors can be problematic. This study aimed to determine the performance of endoscopic ultrasound-guided fine needle aspiration biopsy (EUS FNA) in pancreatic malignancy when prior biopsies performed by CT guidance or ERCP were negative. METHODS: A total of 185 patients with known or suspected pancreatic masses were prospectively evaluated with EUS FNA. Before EUS FNA, all patients were evaluated with abdominal CT (61 with CT-guided biopsy) and 91 with ERCP (41 had brushings or biopsy). RESULTS: EUS had greater sensitivity than CT in detecting a mass (99% vs 57%, p < 0.0001). In 58 patients with negative CT-guided biopsies, EUS FNA had 90% sensitivity for malignancy, 50% specificity for benign disease and 84% accuracy. Similarly, in 36 patients with negative ERCP tissue sampling, results for EUS FNA were 94%, 67% and 92%, respectively. Complications were mild and infrequent (0.5%). CONCLUSION: EUS FNA of pancreatic masses safely and accurately diagnoses pancreatic malignancy when prior biopsy techniques have been unsuccessful.

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Metadata

Authors
Harewood, G.
Venue
The American Journal of Gastroenterology
Published
2002-06
Volume
97
Issue
6
Pages
1386-1391
ISSN
0002-9270 (ISSN-L)
OpenAlex
W2126658009
Cited by
414
References
14
FWCI
6.99
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Endosonography-guided fine needle aspiration biopsy in the evaluation of pancreatic masses. https://app.cochat.ai/papers/10.1016/s0002-9270(02)04133-3
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Harewood, G. (2002). Endosonography-guided fine needle aspiration biopsy in the evaluation of pancreatic masses. The American Journal of Gastroenterology. https://doi.org/10.1016/s0002-9270(02)04133-3

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