The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Endosonography-guided fine needle aspiration biopsy in the evaluation of pancreatic masses
Abstract
OBJECTIVES: Diagnosis of pancreatic tumors can be problematic. This study aimed to determine the performance of endoscopic ultrasound-guided fine needle aspiration biopsy (EUS FNA) in pancreatic malignancy when prior biopsies performed by CT guidance or ERCP were negative. METHODS: A total of 185 patients with known or suspected pancreatic masses were prospectively evaluated with EUS FNA. Before EUS FNA, all patients were evaluated with abdominal CT (61 with CT-guided biopsy) and 91 with ERCP (41 had brushings or biopsy). RESULTS: EUS had greater sensitivity than CT in detecting a mass (99% vs 57%, p < 0.0001). In 58 patients with negative CT-guided biopsies, EUS FNA had 90% sensitivity for malignancy, 50% specificity for benign disease and 84% accuracy. Similarly, in 36 patients with negative ERCP tissue sampling, results for EUS FNA were 94%, 67% and 92%, respectively. Complications were mild and infrequent (0.5%). CONCLUSION: EUS FNA of pancreatic masses safely and accurately diagnoses pancreatic malignancy when prior biopsy techniques have been unsuccessful.
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Cited by
Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors
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Imaging diagnosis of pancreatic cancer: A state-of-the-art review
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Detection of K‐ras gene mutation by liquid biopsy in patients with pancreatic cancer
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The role of endoscopy in the evaluation and management of patients with solid pancreatic neoplasia
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Metadata
- Authors
- Harewood, G.
- Venue
- The American Journal of Gastroenterology
- Published
- 2002-06
- Volume
- 97
- Issue
- 6
- Pages
- 1386-1391
- ISSN
- 0002-9270 (ISSN-L)
- OpenAlex
- W2126658009
- Cited by
- 414
- References
- 14
- FWCI
- 6.99
- Type
- journal article
- Language
- en
- Open access
- closed
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