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Fetal echocardiographic screening for congenital heart disease: The importance of the four-chamber view
Open accessAbstract
The four-chamber view of the heart has been proposed as a screening method for obstetrical sonographers to assess the fetus for the presence of congenital heart disease. We examined the fetuses in 1022 pregnancies and found 74 structurally abnormal hearts. Seventy-one of these (96%) were found to have an abnormality as seen in the four-chamber view. The four-chamber view of the heart had 92% sensitivity and 99.7% specificity in the detection of congenital heart disease. The positive predictive value was 95.8%, and the negative predictive value was 99.4%. We conclude that the four-chamber view may be a useful screen for the presence of congenital heart disease and should be included as a part of all routine obstetric ultrasound examinations.
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Cited by
ISUOG Practice Guidelines (updated): sonographic screening examination of the fetal heart
Carvalho, J., Allan, L., Chaoui, R., Copel, J., DeVore, G., Hecher, K., Lee, W., Munoz, H., Paladini, D., Tutschek, B., et al. (2013) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.12403 · Cited by 681
Self-citationSpatio‐temporal image correlation (STIC): new technology for evaluation of the fetal heart
DeVore, G. R., Falkensammer, P., Sklansky, M. S., & Platt, L. D. (2003) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.217 · Cited by 362
Stümpflen, I., Stümpflen, A., Wimmer, M., & Bernaschek, G. (1996) · The Lancet · doi:10.1016/s0140-6736(96)04069-x · Cited by 294
Xu, L., Liu, M., Shen, Z., Wang, H., Liu, X., Wang, X., Wang, S., Li, T., Yu, S., Hou, M., et al. (2020) · Computerized Medical Imaging and Graphics · doi:10.1016/j.compmedimag.2019.101690 · Cited by 87
Del Bianco, A., Russo, S., Lacerenza, N., Rinaldi, M., Rinaldi, G., Nappi, L., & Greco, P. (2006) · Journal of Perinatal Medicine · doi:10.1515/jpm.2006.059 · Cited by 67
Metadata
- Authors
- Copel, J. A., Pilu, G., Green, J., Hobbins, J. C., & Kleinman, C. S.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1987-09
- Volume
- 157
- Issue
- 3
- Pages
- 648-655
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2033798774
- Cited by
- 287
- References
- 0
- FWCI
- 9.22
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Fetal echocardiographic screening for congenital heart disease: The importance of the four-chamber view. https://app.cochat.ai/papers/10.1016/s0002-9378(87)80022-4
- The paper
- Copel, J. A., Pilu, G., Green, J., Hobbins, J. C., & Kleinman, C. S. (1987). Fetal echocardiographic screening for congenital heart disease: The importance of the four-chamber view. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/s0002-9378(87)80022-4
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
