The Epidemic of Orthostatic Tachycardia and Orthostatic Intolerance

Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy

The Consensus Committee of the American Autonomic Society and the American Academy of Neurology (1996) · Neurology · doi:10.1212/wnl.46.5.1470 · Cited by 1,247

The vasovagal response

van Lieshout, J. J., Wieling, W., Karemaker, J. M., & Eckberg, D. L. (1991) · Clinical Science · doi:10.1042/cs0810575 · Cited by 323

The Diagnosis and Treatment of Baroreflex Failure

Robertson, D., Hollister, A. S., Biaggioni, I., Netterville, J. L., Mosqueda‐Garcia, R., & Robertson, R. M. (1993) · New England Journal of Medicine · doi:10.1056/nejm199311113292003 · Cited by 321

Idiopathic Hypovolemia

FOUAD, F. M., TADENA-THOME, L., BRAVO, E. L., & TARAZI, R. C. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-104-3-298 · Cited by 154

Provocation of hypotension and pain during upright tilt table testing in adults with fibromyalgia.

Bou-Holaigah, I., Calkins, H. G., Ja, F., Tunin, C., Hc, C., Js, K., & Rowe, P. C. (1997) · PubMed · Cited by 146

Malignant Vagotonia Due to Selective Baroreflex Failure

Jordan, J., Shannon, J. R., Black, B. K., Costa, F., Ertl, A. C., Furlan, R., Biaggioni, I., & Robertson, D. (1997) · Hypertension · doi:10.1161/01.hyp.30.5.1072 · Cited by 79

Yohimbine in neurally mediated syncope. Pathophysiological implications.

Mosqueda‐Garcia, R., Fernandez-Violante, R., Tank, J., Snell, M., Cunningham, G., & Furlan, R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3050 · Cited by 48

Neurally Mediated Syncope and Syncope Due to Autonomic Failure: Differences and Similarities

Kaufmann, H. (1997) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-199705000-00003 · Cited by 41

Central Autonomic Network

Shouman, K., & Benarroch, E. E. (2021) · Springer eBooks · doi:10.1007/978-3-030-62263-3_2 · Cited by 33

CLINICAL APPROACH TO DIAGNOSIS OF SYNCOPE

Benditt, D. G., Lurie, K. G., & Fabian, W. H. (1997) · Cardiology Clinics · doi:10.1016/s0733-8651(05)70328-3 · Cited by 23

Dysautonomia, Hypermobility Spectrum Disorders and Mast Cell Activation Syndrome as Migraine Comorbidities

Blitshteyn, S. (2023) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-023-01307-w · Cited by 36

Transdermal auricular vagus stimulation for the treatment of postural tachycardia syndrome

Diedrich, A., Urechie, V., Shiffer, D., Rigo, S., Minonzio, M., Cairo, B., Smith, E. C., Okamoto, L. E., Barbic, F., Bisoglio, A., et al. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102886 · Cited by 36

Treatment of orthostatic hypotension

Oldenburg, O. (2002) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(02)00213-8 · Cited by 33

How COVID‐19 can cause autonomic dysfunctions and postural orthostatic syndrome? A Review of mechanisms and evidence

Hassani, M., Jouzdani, A. F., Motarjem, S., Ranjbar, A., & Khansari, N. (2021) · Neurology and Clinical Neuroscience · doi:10.1111/ncn3.12548 · Cited by 32

Improvement in Functioning and Psychological Distress in Adolescents With Postural Orthostatic Tachycardia Syndrome Following Interdisciplinary Treatment

Bruce, B. K., Harrison, T. E., Bee, S. M., Luedtke, C. A., Porter, C.-B. J., Fischer, P. R., Hayes, S. E., Allman, D. A., Ale, C. M., & Weiss, K. E. (2016) · Clinical Pediatrics · doi:10.1177/0009922816638663 · Cited by 31

Noise-Enhanced Heart Rate and Sympathetic Nerve Responses to Oscillatory Lower Body Negative Pressure in Humans

Hidaka, I., Ando, S., Shigematsu, H., Sakai, K., Setoguchi, S., Seto, T., Hirooka, Y., Takeshita, A., & Yamamoto, Y. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.2.559 · Cited by 30

Sex differences in vasoconstrictor reserve during 70 deg head‐up tilt

Jarvis, S. S., Florian, J. P., Curren, M. J., & Pawelczyk, J. A. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.048819 · Cited by 29

Free-weight resistance exercise on pulse wave reflection and arterial stiffness between sexes in young, resistance-trained adults

Kingsley, J. D., Tai, Y. L., Mayo, X., Glasgow, A., & Marshall, E. (2017) · European Journal of Sport Science · doi:10.1080/17461391.2017.1342275 · Cited by 28

Comparison of Autonomic Control of Blood Pressure During Standing and Artificial Gravity Induced via Short-Arm Human Centrifuge

Verma, A. K., Xu, D. Z., Bruner, M. L., Garg, A., Goswami, N., Blaber, A. P., & Tavakolian, K. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00712 · Cited by 28

Ivabradine in Postural Orthostatic Tachycardia Syndrome: A Review of the Literature

Tahir, F., Arif, T. B., Majid, Z., Ahmed, J., & Khalid, M. (2020) · Cureus · doi:10.7759/cureus.7868 · Cited by 28

Small Heart With Low Cardiac Output for Orthostatic Intolerance in Patients With Chronic Fatigue Syndrome

Miwa, K., & Fujita, M. (2011) · Clinical Cardiology · doi:10.1002/clc.20962 · Cited by 28

Contrasting neurovascular findings in chronic orthostatic intolerance and neurocardiogenic syncope

Stewart, J. M., & Weldon, A. (2003) · Clinical Science · doi:10.1042/cs1040329 · Cited by 28

Difference between Supine and Upright Blood Pressure Associates to the Efficacy of Midodrine on Postural Orthostatic Tachycardia Syndrome (POTS) in Children

Deng, W., Liu, Y., Liu, A. D., Holmberg, L., Ochs, T., Li, X., Yang, J., Tang, C., Du, J., & Jin, H. (2013) · Pediatric Cardiology · doi:10.1007/s00246-013-0843-9 · Cited by 28

Assessment of O-methylated catecholamine levels in plasma and urine for diagnosis of autonomic disorders

Oeltmann, T., Carson, R. P., Shannon, J. R., Ketch, T., & Robertson, D. (2004) · Autonomic Neuroscience · doi:10.1016/j.autneu.2004.08.013 · Cited by 27

Recent advances in orthostatic hypotension presenting orthostatic dizziness or vertigo

Kim, H. A., Yi, H., & Lee, H. (2015) · Neurological Sciences · doi:10.1007/s10072-015-2363-2 · Cited by 26

Use of Methylphenidate in the Treatment of Patients Suffering From Refractory Postural Tachycardia Syndrome

Kanjwal, K., Saeed, B., Karabin, B. L., Kanjwal, Y., & Grubb, B. P. (2010) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e3181dd21d2 · Cited by 26

Dysautonomia in hypermobile Ehlers–Danlos syndrome and hypermobility spectrum disorders is associated with exercise intolerance and cardiac atrophy

Maya, T. R., Fettig, V. M., Mehta, L., Gelb, B. D., & Kontorovich, A. (2021) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.62446 · Cited by 30

Sex differences in limb vasoconstriction responses to increases in transmural pressures

Lott, M. E. J., Hogeman, C., Herr, M. D., Bhagat, M., & Sinoway, L. I. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00248.2008 · Cited by 26

Phenylephrine alteration of cerebral blood flow during orthostasis: effect on n-back performance in chronic fatigue syndrome

Medow, M. S., Sood, S., Messer, Z. R., Dzogbeta, S., Terilli, C., & Stewart, J. M. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00527.2014 · Cited by 25

Acute hemodynamic effects of a selective serotonin reuptake inhibitor in postural tachycardia syndrome: A randomized, crossover trial

Mar, P. L., Raj, V., Black, B. K., Biaggioni, I., Shibao, C. A., Paranjape, S. Y., Dupont, W. D., Robertson, D., & Raj, S. R. (2014) · Journal of Psychopharmacology · doi:10.1177/0269881113512911 · Cited by 24

Limb venous tone and responsiveness in hypertensive humans

Delaney, E. P., Young, C. N., DiSabatino, A., Stillabower, M. E., & Farquhar, W. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90574.2008 · Cited by 24

Altered oscillatory cerebral blood flow velocity and autoregulation in postural tachycardia syndrome

Medow, M. S., Del Pozzi, A. T., Messer, Z. R., Terilli, C., & Stewart, J. M. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00234 · Cited by 23

Confounders of Vasovagal Syncope

Nwazue, V. C., & Raj, S. R. (2013) · Cardiology Clinics · doi:10.1016/j.ccl.2012.09.004 · Cited by 23

Baroreflex Sensitivity Predicts Short-Term Outcome of Postural Tachycardia Syndrome in Children

Li, H., Liao, Y., Wang, Y., Liu, P., Sun, C., Chen, Y., Tang, C., Jin, H., & Du, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167525 · Cited by 23

Cardiac dysfunction and orthostatic intolerance in patients with myalgic encephalomyelitis and a small left ventricle

Miwa, K. (2014) · Heart and Vessels · doi:10.1007/s00380-014-0510-y · Cited by 23

Electroacupuncture improves orthostatic tolerance in healthy individuals via improving cardiac function and activating the sympathetic system

Sun, J., Sang, H., Yang, C., Dong, H., Lei, C., Lu, Y., Ma, Y., Zhou, X., Sun, X., & Xiong, L. (2012) · EP Europace · doi:10.1093/europace/eus220 · Cited by 23

Postural Orthostatic Tachycardia Predicts Early Conversion to Multiple Sclerosis after Clinically Isolated Syndrome

Habek, M., Skorić, M. K., Crnošija, L., Gabelić, T., Barun, B., & Adamec, I. (2017) · European Neurology · doi:10.1159/000469707 · Cited by 23

Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options

Wagoner, A. L., Shaltout, H. A., Fortunato, J. E., & Diz, D. I. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00583.2015 · Cited by 22

Hemodynamic characteristics of postural hyperventilation: POTS with hyperventilation versus panic versus voluntary hyperventilation

Stewart, J. M., Pianosi, P. T., Shaban, M., Terilli, C., Svistunova, M., Visintainer, P., & Medow, M. S. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00377.2018 · Cited by 22

Management of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia and Vasovagal Syncope

Raj, S. R., & Sheldon, R. S. (2016) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2016.7.2 · Cited by 24

Vestibulosympathetic reflex during the early follicular and midluteal phases of the menstrual cycle

Lawrence, J. E., Ray, C. A., & Carter, J. R. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00056.2008 · Cited by 21

Clinical Course of Transgender Adolescents with Complicated Postural Orthostatic Tachycardia Syndrome Undergoing Hormonal Therapy in Gender Transition: A Case Series

Boris, J. R., McClain, Z., & Bernadzikowski, T. (2019) · Transgender Health · doi:10.1089/trgh.2019.0041 · Cited by 23

Impaired Endothelial Function in Patients With Postural Tachycardia Syndrome

Chopoorian, A. H., Wahba, A., Celedonio, J. E., Nwazue, V. C., Smith, E. C., Garland, E. M., Paranjape, S. Y., Okamoto, L. E., Black, B. K., Biaggioni, I., et al. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.16238 · Cited by 20

Postural Orthostatic Tachycardia Syndrome: Anesthetic Implications in the Obstetric Patient

McEvoy, M. D., Low, P. A., & Hebbar, L. (2006) · Anesthesia & Analgesia · doi:10.1213/01.ane.0000246815.39197.2b · Cited by 21

Measurement of inferior vena cava diameter for evaluation of venous return in subjects onday 10of a bed-rest experiment

Ishizaki, Y., Fukuoka, H., Ishizaki, T., Kino, M., Higashino, H., Ueda, N., Fujii, Y., & Kobayashi, Y. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01097.2003 · Cited by 21

Caloric Restriction Decreases Orthostatic Tolerance Independently from 6° Head-Down Bedrest

Florian, J. P., Baisch, F. J., Heer, M. A., & Pawelczyk, J. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0118812 · Cited by 21

Postural Tachycardia, Orthostatic Intolerance, and the Chronic Fatigue Syndrome

Grubb, B. P., Calkins, H. G., & Rowe, P. C. (2005) · Wiley eBooks · doi:10.1002/9780470994801.ch13 · Cited by 23

Disruption of phase synchronization between blood pressure and muscle sympathetic nerve activity in postural vasovagal syncope

Schwartz, C. E., Lambert, É., Medow, M. S., & Stewart, J. M. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00415.2013 · Cited by 20

Orthostatic Circulatory Disorders: From Nosology to Nuts and Bolts

Gutkin, M. C., & Stewart, J. M. (2016) · American Journal of Hypertension · doi:10.1093/ajh/hpw023 · Cited by 20

Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome

Shirey-Rice, J. K., Klar, R., Fentress, H. M., Redmon, S. N., Sabb, T. R., Krueger, J. J., Wallace, N. M., Appalsamy, M., Finney, C., Lonce, S., et al. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.012203 · Cited by 20

Anaesthetic management of a parturient with the postural orthostatic tachycardia syndrome: a case report

Corbett, W. L., Reiter, C. M., Schultz, J. R., Kanter, R. J., & Habib, A. S. (2006) · British Journal of Anaesthesia · doi:10.1093/bja/ael105 · Cited by 20

Clinical significance of orthostatic dizziness in the diagnosis of benign paroxysmal positional vertigo and orthostatic intolerance

Jeon, E., Park, Y. S., Park, S. N., Park, K. H., Kim, D., Nam, I., & Chang, K. (2013) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2013.04.005 · Cited by 20

Clinical features of hyperadrenergic postural tachycardia syndrome in children

Zhang, Q., Chen, X., Li, J., & Du, J. (2014) · Pediatrics International · doi:10.1111/ped.12392 · Cited by 20

Orthostatic intolerance and the postural tachycardia syndrome: genetic and environment pathophysiologies

Robertson, D., Shannon, J. R., Biaggioni, I., Ertl, A. C., Diedrich, A., Carson, R. P., Furlan, R., Jacob, G., Jordan, J., & and the Cygnus Research Team (2000) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240000353 · Cited by 19

Cerebral Blood Flow in Orthostatic Intolerance

Khan, M. S., Miller, A. J., Ejaz, A., Molinger, J., Goyal, P., MacLeod, D. B., SWAVELY, A. G., WILSON, E. R., Pergola, M., Tandri, H. S., et al. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.124.036752 · Cited by 22

Gravity Threshold and Dose Response Relationships: Health Benefits Using a Short Arm Human Centrifuge

Kourtidou‐Papadeli, C., Frantzidιs, C. A., Gilou, S. C., Plomariti, C. S., Nday, C. M., Karnaras, D., Bakas, L., Bamidis, P. D., & Vernikos-Danellis, J. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.644661 · Cited by 19

Postural Orthostatic Tachycardia Syndrome (POTS)

Mizumaki, K. (2011) · Journal of Arrhythmia · doi:10.1016/s1880-4276(11)80031-1 · Cited by 19

Manometric Abnormalities in the Postural Orthostatic Tachycardia Syndrome: A Case Series

Huang, R. J., Chun, C. L., Friday, K. J., & Triadafilopoulos, G. (2013) · Digestive Diseases and Sciences · doi:10.1007/s10620-013-2865-9 · Cited by 18

Blunted cerebral blood flow velocity in response to a nitric oxide donor in postural tachycardia syndrome

Del Pozzi, A. T., Pandey, A., Medow, M. S., Messer, Z. R., & Stewart, J. M. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00194.2014 · Cited by 17

Functional capacity and quality of life in the postural tachycardia syndrome: A retrospective cross-sectional study

Hutt, E., Vajapey, R. S., Iterson, E. H. V., Jaeger, F. J., Cho, L., Ahmed, H. M., & Mayuga, K. A. (2020) · Annals of Medicine and Surgery · doi:10.1016/j.amsu.2020.06.013 · Cited by 18

Simulated microgravity effects on the rat carotid and femoral arteries: role of contractile protein expression and mechanical properties of the vessel wall

Hwang, S., Shelkovnikov, S., & Purdy, R. E. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01020.2006 · Cited by 17

Sex and estrous cycle differences in the behavioral effects of high-strength static magnetic fields: role of ovarian steroids

Cason, A. M., DenBleyker, M., Ferrence, K., Smith, J. C., & Houpt, T. A. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00305.2005 · Cited by 17

Dysautonomia and Headache in the Pediatric Population

Wig, R., & Oakley, C. B. (2019) · Headache The Journal of Head and Face Pain · doi:10.1111/head.13659 · Cited by 16

Orthostatic intolerance with tachycardia (postural tachycardia syndrome) and without (hypocapnic cerebral hypoperfusion) represent a spectrum of the same disorder

Novák, P., Systrom, D. M., Witte, A. V., & Marciano, S. P. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1476918 · Cited by 17

Supine Parasympathetic Withdrawal and Upright Sympathetic Activation Underly Abnormalities of the Baroreflex in Postural Tachycardia Syndrome

Stewart, J. M., Warsy, I. A., Visintainer, P., Terilli, C., & Medow, M. S. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.16113 · Cited by 16

Muscle sympathetic nerve activity and hemodynamic responses to venous distension: does sex play a role?

Mansur, D. E., Campos, M. O., Mattos, J. D., Paiva, A. C. S., Rocha, M. P., Videira, R. L. D. R., Macefield, V. G., da Nóbrega, A. C. L., & Fernandes, I. A. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00702.2018 · Cited by 18

No increased herniation of the cerebellar tonsils in a group of patients with orthostatic intolerance

Garland, E. M., Anderson, J. C., Black, B. K., KESSLER, R. M., Konrad, P. E., & Robertson, D. (2002) · Clinical Autonomic Research · doi:10.1007/s10286-002-0051-9 · Cited by 16

Splanchnic venous compression enhances the effects of ß-blockade in the treatment of postural tachycardia syndrome

Smith, E. C., Diedrich, A., Raj, S. R., Gamboa, A., Shibao, C. A., Black, B. K., Peltier, A., Paranjape, S. Y., Biaggioni, I., & Okamoto, L. E. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.016196 · Cited by 16

Differential influences of dietary sodium on blood pressure regulation based on race and sex

Robinson, A. T., Wenner, M. M., & Charkoudian, N. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102873 · Cited by 16

Microneurographic research in women

Fu, Q. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00278 · Cited by 15

Autonomic control after blockade of the norepinephrine transporter: a model of orthostatic intolerance

Carson, R. P., Diedrich, A., & Robertson, D. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00033.2002 · Cited by 15

The chronic fatigue syndrome is a disease of the autonomic nervous system. Sometimes.

Freeman, R. L. (2002) · Clinical Autonomic Research · doi:10.1007/s10286-002-0058-2 · Cited by 16

Nitric Oxide and Regulation of Heart Rate in Patients With Postural Tachycardia Syndrome and Healthy Subjects

Gamboa, A. C., Okamoto, L. E., Raj, S. R., Diedrich, A., Shibao, C. A., Robertson, D., & Biaggioni, I. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00203 · Cited by 14

Postural orthostatic tachycardia syndrome is associated with platelet storage pool deficiency

Gunning, W. T., Karabin, B. L., Blomquist, T. M., & Grubb, B. P. (2016) · Medicine · doi:10.1097/md.0000000000004849 · Cited by 14

Postural Orthostatic Tachycardia Syndrome during pregnancy: A systematic review of the literature

Morgan, K., Chojenta, C., Tavener, M., Smith, A., & Loxton, D. J. (2018) · Autonomic Neuroscience · doi:10.1016/j.autneu.2018.05.003 · Cited by 14

Heart Rate and Heart Rate Difference Predicted the Efficacy of Metoprolol on Postural Tachycardia Syndrome in Children and Adolescents

Wang, S., Zou, R., Cai, H., Wang, Y., Ding, Y., Tan, C., Yang, M., Li, F., & Wang, C. (2020) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2020.05.017 · Cited by 14

Sympathetic neural activity, sex dimorphism, and postural tachycardia syndrome

Bonyhay, I., & Freeman, R. L. (2007) · Annals of Neurology · doi:10.1002/ana.21090 · Cited by 14

Orthostatic intolerance in post-concussion patients

Gould, S. J., Cochrane, G. D., Johnson, J., Hebson, C. L., & Kazamel, M. (2021) · The Physician and Sportsmedicine · doi:10.1080/00913847.2021.1953357 · Cited by 14

Postural Orthostatic Tachycardia Syndrome (POTS) in Denmark: Increasingly recognized or new epidemic?

Brinth, L. S., Pors, K., Spahic, J. M., Sutton, R., Fedorowski, A., & Mehlsen, J. (2018) · Autonomic Neuroscience · doi:10.1016/j.autneu.2018.03.001 · Cited by 13

Molecular genetics of transporters for norepinephrine, dopamine, and serotonin in behavioral traits and complex diseases

Lesch, K., & Murphy, D. L. (2003) · Springer eBooks · doi:10.1007/978-1-4419-9023-5_23 · Cited by 13

Postural orthostatic tachycardia syndrome: pathophysiology, management, and experimental therapies

Narasimhan, B., Aggarwal, D., Satish, P., Kantharia, B. K., & Aronow, W. S. (2022) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2022.2121697 · Cited by 12

Children With PANS May Manifest POTS

Chan, A. L., Gao, J., Houston, M., Willett, T. A., Farhadian, B., Silverman, M. A., Tran, P., Jaradeh, S. S., Thienemann, M., & Frankovich, J. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.819636 · Cited by 13

Orthostatic intolerance is common in chronic disease — A clinical cohort study

Frith, J., Ng, W., Day, C. P., Payne, B. A. I., Sheerin, N., Gorman, G. S., Jones, D., & Newton, J. L. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.04.175 · Cited by 12

Dynamics of the cardiovascular autonomic regulation during orthostatic challenge is more relaxed in women

Reulecke, S., Charleston-Villalobos, S., Voss, A., González-Camarena, R., González-Hermosillo, J. A., Gaitán-González, M. J., Hernández‐Pacheco, G., Schroeder, R., & Aljama-Corrales, T. (2017) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt-2016-0150 · Cited by 12

Hemodynamic profile and heart rate variability in hyperadrenergic versus non-hyperadrenergic postural orthostatic tachycardia syndrome

Crnošija, L., Skorić, M. K., Adamec, I., Lovrić, M., Junaković, A., Mišmaš, A., Miletić, V., Alfirev, R. Š., Pavelić, A. R., & Habek, M. (2015) · Clinical Neurophysiology · doi:10.1016/j.clinph.2015.08.015 · Cited by 12

Altered profile of baroreflex and autonomic responses to lower body negative pressure in chronic orthostatic intolerance

Lucini, D., Furlan, R., Villa, P., Mosqueda‐Garcia, R., Diedrich, A., Robertson, D., Malliani, A., Porta, A., & Pagani, M. (2004) · Journal of Hypertension · doi:10.1097/01.hjh.0000125457.28861.ad · Cited by 13

Cerebrovascular and cardiovascular responses associated with orthostatic intolerance and tachycardia

Harms, M. P. M., & LIESHOUT, J. J. V. (2001) · Clinical Autonomic Research · doi:10.1007/bf02317800 · Cited by 12

Gene Organization and Polymorphisms of Monoamine Transporters: Relationship to Psychiatric and Other Complex Diseases

Hahn, M. K., & Blakely, R. (2003) · Humana Press eBooks · doi:10.1385/1-59259-158-2:111 · Cited by 12

Increased prevalence of autonomic dysfunction due to postural orthostatic tachycardia syndrome in patients with eosinophilic gastrointestinal disorders

Huang, K. Z., & Dellon, E. S. (2019) · Journal of Gastrointestinal and Liver Diseases · doi:10.15403/jgld.2014.1121.281.syd · Cited by 12

Influence of an Insertion Variant in the 5ʹUTR of the Endothelin-1 Gene on Orthostatic Intolerance

Winker, R., Rüdiger, H. W., Garland, E. M., Diedrich, A., Biaggioni, I., Robertson, D., Ponocny, I., & Cascorbi, I. (2005) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200510000-00003 · Cited by 11

Using thermal stress to model aspects of disease states

Wilson, T. E., Klabunde, R. E., & Monahan, K. D. (2014) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2014.03.003 · Cited by 11

Familial orthostatic tachycardia

Keller, N. R., & Robertson, D. (2006) · Current Opinion in Cardiology · doi:10.1097/01.hco.0000221577.41125.c8 · Cited by 11

Orthostatic Intolerance in Behcet's Disease

Tellioğlu, T., & Robertson, D. (2001) · Autonomic Neuroscience · doi:10.1016/s1566-0702(01)00243-0 · Cited by 11

EDITORIAL: Why do young women (donors) faint?

Fu, Q., & Levine, B. D. (2010) · Transfusion · doi:10.1111/j.1537-2995.2010.02593.x · Cited by 10

Cerebral blood flow and end-tidal CO2 predict lightheadedness during head-up tilt in patients with orthostatic intolerance

Coelho, F. M. S., Cremaschi, R. C., & Novák, P. (2024) · Neurological Sciences · doi:10.1007/s10072-024-07673-8 · Cited by 10

Flow Velocity in Common Carotid Artery

Rasyada, A. R., & Azhim, A. (2018) · IntechOpen eBooks · doi:10.5772/intechopen.80712 · Cited by 11

Animal Model of Neuropathic Tachycardia Syndrome

Carson, R. P., Appalsamy, M., Diedrich, A., Davis, T. L., & Robertson, D. (2001) · Hypertension · doi:10.1161/01.hyp.37.6.1357 · Cited by 10

Low blood pressure and low energy

Tonkin, A. (2004) · Journal of Hypertension · doi:10.1097/00004872-200404000-00002 · Cited by 10

Human Performance Considerations for a Mars Mission

Wickman, L. A. (2006) · IEEE Aerospace Conference (AERO) · doi:10.1109/aero.2006.1656147 · Cited by 9

Postural orthostatic tachycardia syndrome

Brooks, J. K., & Francis, L. A. P. (2006) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2006.0221 · Cited by 9

Water ingestion affects orthostatic challenge-induced blood pressure and heart rate responses in young healthy subjects: gender implications.

Olatunji, L. A., Aaron, A. O., Micheal, O., & Oyeyipo, I. P. (2011) · PubMed · Cited by 9

c-Fos induction by a 14T magnetic field in visceral and vestibular relays of the female rat brainstem is modulated by estradiol

Cason, A. M., Kwon, B., Smith, J. C., & Houpt, T. A. (2010) · Brain Research · doi:10.1016/j.brainres.2010.06.002 · Cited by 9

Cardiac Origins of Postural Orthostatic Tachycardia Syndrome

(2010) · AAP Grand Rounds · doi:10.1542/gr.24-6-73 · Cited by 9

Orthostatic Intolerance

Stewart, J. M. (2000) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v08n02_05 · Cited by 9

Postural Tachycardia Syndrome: Diagnosis and Management in Adolescents and Young Adults

Heyer, G. L. (2017) · Pediatric Annals · doi:10.3928/19382359-20170322-01 · Cited by 10

Takotsubo cardiomyopathy in a patient with postural tachycardia syndrome

Khurana, R. K. (2007) · Clinical Autonomic Research · doi:10.1007/s10286-007-0444-x · Cited by 8

Nausea and Vomiting Related to Autonomic Nervous System Disorders

Abell, T. L., & Parajuli, D. (2016) · Springer eBooks · doi:10.1007/978-3-319-34076-0_7 · Cited by 7

ST-segment changes during tilt table testing for postural tachycardia syndrome: correlation with exercise stress test results

Vajapey, R. S., Hutt, E., Iterson, E. H. V., Ahmed, H. M., & Mayuga, K. A. (2019) · Clinical Autonomic Research · doi:10.1007/s10286-019-00633-9 · Cited by 7

Syncope in Children and Adolescents

Kanjwal, K., & Calkins, H. G. (2013) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2013.08.007 · Cited by 6

Effect of Food Intake on Hemodynamic Parameters during the Tilt-Table Test in Patients with Postural Orthostatic Tachycardia Syndrome

Habek, M., Ruška, B., Crnošija, L., Adamec, I., Junaković, A., & Skorić, M. K. (2019) · Journal of Clinical Neurology · doi:10.3988/jcn.2019.15.2.205 · Cited by 7

The long and winding road of postural orthostatic tachycardia syndrome

Fedorowski, A. (2026) · Journal of Internal Medicine · doi:10.1111/joim.70121

Early Orthostatic Hypotension and Orthostatic Intolerance—More Than an Observation or Annoyance

Singer, W., & Low, P. A. (2017) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2017.2923 · Cited by 8

[Orthostatic intolerance. A review and clinical case].

Freitas, J. P., Almeida, J., Azevedo, E. I., Mj, C., Costa, O., & de Freitas, A. F. (1998) · PubMed · Cited by 1

Postural Orthostatic Tachycardia Syndrome and Chronic Orthostatic Intolerance: Common, Challenging, and Manageable

Klaas, K. M., & Fischer, P. R. (2026) · Pediatric Annals · doi:10.3928/19382359-20260112-02

Hypercapnia and Orthostatic Tolerance in Postural Orthostatic Tachycardia Syndrome

(2020) · Case Medical Research · doi:10.31525/ct1-nct04271878