Alignment of microscopic particles in electric fields and its biological implications
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It is well known that electromagnetic fields cause mechanical forces. If one applies an electrical field to a suspension of microscopic particles, these particles realign themselves along the direction of the field and form pearl-chain-like aggregates. These chains are mostly single stranded but they are frequently multistranded. This phenomenon has been investigated by a number of groups. Here we discuss the dependence of threshold field strength on particle size and frequency. Also, pulsed fields have been thought to be more effective than continuous fields of the same average power in evoking biological effects. Our measurement of the threshold power requirement for the pearl-chain formation indicates that pulsed fields require as much power as continuous fields. The biological significance of pearl-chain formation is briefly discussed.
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A number of nonthermal effects of minor biological consequence have been reported even at low field intensities, including microscopic particle alignment and cell rotation.
“However, a number of nonthermal effects of minor biological consequence have been reported even at low field intensities.These include microscopic particle alignment (i.e., the pearl chain effect; Ref. 6) and cell rotation (7,8).”
From Disruption of cancer cell replication by alternating electric fields (2004) · cites this paper as [6]
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- Authors
- Takashima, S., & Schwan, H. P.
- Venue
- Biophysical Journal
- Publisher
- Elsevier BV
- Published
- 1985-04
- Volume
- 47
- Issue
- 4
- Pages
- 513-518
- ISSN
- 0006-3495 (ISSN-L)
- PMC
- PMC1435134
- OpenAlex
- W2051578169
- Cited by
- 68
- References
- 11
- Citations by year
- 2023: 1 · 2022: 3 · 2020: 2 · 2019: 2 · 2018: 5 · 2017: 3 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 1
- FWCI
- 7.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biophysical Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (HE-01253)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Electromagnetic Fields and Biological Effects
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Electrostatics and Colloid Interactions
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Chemical and Physical Studies
- Keywords
- particle alignment, electric field, particle suspensions, threshold field, particle size dependence, frequency dependence, pulsed fields, continuous fields, biological effects of electromagnetic fields, electrophoretic force
- MeSH terms
- Electricity, Electromagnetic Fields, Emulsions, Particle Size, Silicon, Electromagnetic Phenomena
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