The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors
Open accessAbstract
In human embryonic kidney cells over‐expressing the human vanilloid receptor type 1 (VR1), palmitoylethanolamide (PEA, 0.5–10 μM) enhanced the effect of arachidonoylethanolamide (AEA, 50 nM) on the VR1‐mediated increase of the intracellular Ca 2+ concentration. PEA (5 μM) decreased the AEA half‐maximal concentration for this effect from 0.44 to 0.22 μM. The PEA effect was not due to inhibition of AEA hydrolysis or adhesion to non‐specific sites, since bovine serum albumin (0.01–0.25%) potently inhibited AEA activity, and PEA also enhanced the effect of low concentrations of the VR1 agonists resiniferatoxin and capsaicin. PEA (5 μM) enhanced the affinity of AEA for VR1 receptors as assessed in specific binding assays. These data suggest that PEA might be an endogenous enhancer of VR1‐mediated AEA actions.
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Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
Zygmunt, P. M., Petersson, J., Andersson, D. A., Chuang, H.-H., Sørgård, M., Di Marzo, V., Julius, D., & Högestätt, E. D. (1999) · Nature · doi:10.1038/22761 · Cited by 2,142
Facci, L., Dal Toso, R., Romanello, S., Buriani, A., Skaper, S. D., & Leon, A. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.8.3376 · Cited by 632
De Petrocellis, L., Bisogno, T., Davis, J. B., Pertwee, R. G., & Di Marzo, V. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)02082-2 · Cited by 347
Self-citationRoss, R. A., Gibson, T. M., Brockie, H. C., Leslie, M., Pashmi, G., Craib, S. J., Di Marzo, V., & Pertwee, R. G. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703850 · Cited by 237
Melck, D., Bisogno, T., De Petrocellis, L., Chuang, H.-H., Julius, D., Bifulco, M., & Di Marzo, V. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1105 · Cited by 188
Cited by
Iannotti, F. A., Di Marzo, V., & Petrosino, S. (2016) · Progress in Lipid Research · doi:10.1016/j.plipres.2016.02.002 · Cited by 357
Self-citationPetrosino, S., & Di Marzo, V. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13580 · Cited by 328
Self-citationChanges in spinal and supraspinal endocannabinoid levels in neuropathic rats
Petrosino, S., Palazzo, E., de Novellis, V., Bisogno, T., Rossi, F., Maione, S., & Di Marzo, V. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.08.011 · Cited by 227
Re, G., Barbero, R., Miolo, A., & Di Marzo, V. (2007) · The Veterinary Journal · doi:10.1016/j.tvjl.2005.10.003 · Cited by 199
T-Type Calcium Channel Inhibition Underlies the Analgesic Effects of the Endogenous Lipoamino Acids
Barbara, G., Alloui, A., Nargeot, J., Lory, P., Eschalier, A., Bourinet, E., & Chemin, J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2919-09.2009 · Cited by 125
Metadata
- Authors
- De Petrocellis, L., Davis, J. B., & Di Marzo, V.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2001-09-27
- Volume
- 506
- Issue
- 3
- Pages
- 253-256
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1998612393
- Cited by
- 204
- References
- 5
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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