The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens
Open accessAbstract
The recent discovery that an additional estrogen receptor (ER) subtype is present in various rat, mouse and human tissues has advanced our understanding of the mechanisms underlying estrogen signalling. The discovery of a second ER subtype (ER β) suggests the existence of two previously unrecognised pathways of estrogen signalling: via the ER β subtype in tissues exclusively expressing this subtype and via the formation of heterodimers in tissues expressing both ER subtypes. Various models have been suggested as explanations for the striking cell‐ and promoter‐specific effects of estrogens and anti‐estrogens, all on the basis of the assumption that only a single ER gene exists. This minireview describes several of these models and focuses on the potential role which the novel ER β subtype might have in this regard.
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Cites
Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man
Smith, E. P., Boyd, J., Frank, G. R., Takahashi, H., Cohen, R. M., Specker, B., Williams, T. C., Lubahn, D. B., & Korach, K. S. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410203311604 · Cited by 2,471
Ito, Y., Fisher, C. R., Conte, F. A., Grumbach, M. M., & Simpson, E. R. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.24.11673 · Cited by 218
Cited by
Loss of ERβ expression as a common step in estrogen-dependent tumor progression
Bardin, A., Boulle, N., Lazennec, G., Vignon, F., & Pujol, P. (2004) · Endocrine-Related Cancer · doi:10.1677/erc.1.00800 · Cited by 417
Webb, P. M., Nguyen, P. T., Valentine, C. D., Lopez, G. N., Kwok, G. R., McInerney, E. M., Katzenellenbogen, B. S., Enmark, E., Gustafsson, J.-Α., Nilsson, S. V., et al. (1999) · Molecular Endocrinology · doi:10.1210/me.13.10.1672 · Cited by 396
Self-citationShughrue, P. J., Lane, M. V., Scrimo, P. J., & Merchenthaler, I. (1998) · Steroids · doi:10.1016/s0039-128x(98)00054-3 · Cited by 285
Critchley, H. O. D., Brenner, R. M., Henderson, T. A., Williams, K., Nayak, N. R., Slayden, O. D., Millar, M. R., & Saunders, P. T. K. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.3.7317 · Cited by 210
Österlund, M. K., Keller, E., & Hurd, Y. L. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00443-1 · Cited by 174
Metadata
- Authors
- Kuiper, G. G. J. M., & Gustafsson, J.-Å.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1997-06-23
- Volume
- 410
- Issue
- 1
- Pages
- 87-90
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2000483250
- Cited by
- 400
- References
- 2
- FWCI
- 20.26
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kuiper, G. G. J. M., & Gustafsson, J.-Å. (1997). The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens. FEBS Letters. https://doi.org/10.1016/s0014-5793(97)00413-4
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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