The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β‐glucosidase activity
Open accessAbstract
Flavonoid and isoflavonoid glycosides are common dietary phenolics which may be absorbed from the small intestine of humans. The ability of cell‐free extracts from human small intestine and liver to deglycosylate various (iso)flavonoid glycosides was investigated. Quercetin 4′‐glucoside, naringenin 7‐glucoside, apigenin 7‐glucoside, genistein 7‐glucoside and daidzein 7‐glucoside were rapidly deglycosylated by both tissue extracts, whereas quercetin 3,4′‐diglucoside, quercetin 3‐glucoside, kaempferol 3‐glucoside, quercetin 3‐rhamnoglucoside and naringenin 7‐rhamnoglucoside remained unchanged. The K m for hydrolysis of quercetin 4′‐glucoside and genistein 7‐glucoside was ∼32±12 and ∼14±3 μM in both tissues respectively. The enzymatic activity of the cell‐free extracts exhibits similar properties to the cytosolic broad‐specificity β‐glucosidase previously described in mammals.
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Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Cited by
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Dietary Intake and Bioavailability of Polyphenols
Scalbert, A., & Williamson, G. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.8.2073s · Cited by 3,658
Self-citationHealth effects of quercetin: From antioxidant to nutraceutical
Boots, A. W., Haenen, G. R. M. M., & Bast, A. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.03.008 · Cited by 2,121
Anthocyanins: Natural Colorants with Health-Promoting Properties
He, J., & Giusti, M. M. (2010) · Annual Review of Food Science and Technology · doi:10.1146/annurev.food.080708.100754 · Cited by 1,637
Flavonoids in Food and Their Health Benefits
YAO, L. H., JIANG, Y. M., SHI, J., TOM�S-BARBER�N, F. A., DATTA, N., SINGANUSONG, R., & CHEN, S. S. (2004) · Plant Foods for Human Nutrition · doi:10.1007/s11130-004-0049-7 · Cited by 1,545
Metadata
- Authors
- Day, A. J., DuPont, M. S., Ridley, S., Rhodes, M., Rhodes, M. J. C., Morgan, M. R. A., & Williamson, G.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1998-09-25
- Volume
- 436
- Issue
- 1
- Pages
- 71-75
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2008905101
- Cited by
- 729
- References
- 1
- FWCI
- 15.29
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Day, A. J., DuPont, M. S., Ridley, S., Rhodes, M., Rhodes, M. J. C., Morgan, M. R. A., & Williamson, G. (1998). Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β‐glucosidase activity. FEBS Letters. https://doi.org/10.1016/s0014-5793(98)01101-6
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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