Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope
Open accessAbstract
Sixty-two women with the polycystic ovarian syndrome were treated by systematic electrocautery of the ovarian capsule performed by laparoscopy. Ovulation occurred within 3 months in 92%. Regular menstrual cycles were established in 51 patients (86%) and plasma progesterone levels suggested that these were ovulatory. Seven of nine women who had been resistant to treatment with clomiphene, 150 mg daily, and human chorionic gonadotropin, 6000 to 9000 IU, ovulated after electrocauterization. The remaining two women responded to stimulation with clomiphene. Pregnancy occurred in 24 of 35 subjects who were involuntarily infertile (69%), with the pregnancy rate increasing to 80% with the inclusion of the women sensitive to clomiphene. These findings support the theory that ovulation is triggered by local factors within the ovary itself.
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Laparoscopic ovarian 'drilling' was first described in 1984 with minor variations developed subsequently; all are characterised by an altered endocrine profile following surgery.
“Laparoscopic ovarian 'drilling' was first described in 1984 254 with minor variations developed subsequently; all are characterised by an altered endocrine profile following surgery.”
From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [254]
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Hendriks, M. L., van der Valk, P., Lambalk, C. B., Broeckaert, M. A. M., Homburg, R., & Hompes, P. G. A. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.10.046 · Cited by 35 · see citing works
Sakata, M., Tasaka, K., Kurachi, H., Terakawa, N., Miyake, A., & Tanizawa, O. (1990) · Fertility and Sterility · doi:10.1016/s0015-0282(16)53451-7 · Cited by 35 · see citing works
Hashim, H. A., Foda, O., & Rakhawy, M. E. (2018) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-018-4680-1 · Cited by 34 · see citing works
- Authors
- Gjönnaess, H.
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 1984-01
- Volume
- 41
- Issue
- 1
- Pages
- 20-25
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W117239984
- Cited by
- 381
- References
- 17
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 7 · 2022: 14 · 2021: 3 · 2020: 11 · 2019: 5 · 2018: 10 · 2017: 5 · 2016: 5 · 2015: 13 · 2014: 8 · 2013: 14 · 2012: 8
- FWCI
- 3.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- polycystic ovary syndrome, laparoscopic ovarian surgery, ovulation induction, clomiphene citrate resistance, human chorionic gonadotropin, menstrual cycle regularity, pregnancy rate
- MeSH terms
- Adolescent, Adult, Child, Clomiphene, Electrocoagulation, Female, Humans, Infertility, Female, Middle Aged, Ovulation, Polycystic Ovary Syndrome, Pregnancy, Progesterone
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