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Cited by 206Reproductive Health and TechnologiesAlcohol Consumption and Health EffectsReproductive Biology and Fertility

The DOI matches its Crossref record; 38 of the 39 references it cites were found in a registry or an index.

Alcohol and caffeine consumption and decreased fertility

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Hakim, Rosemarie B, Gray, Ronald H, Zacur, Howard·1998·Fertility and Sterility
DOI 10.1016/s0015-0282(98)00257-x
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Abstract

OBJECTIVE: To examine the effects of alcohol and caffeine on conception. DESIGN: Prospective observational study. SETTING: Healthy volunteers in two manufacturing facilities. PATIENT(S): One hundred twenty-four women who provided daily urine samples for measurement of steroid hormones and hCG, and prospective information about alcohol and caffeine consumption. MAIN OUTCOME MEASURE(S): Probability of conception per 100 menstrual cycles. RESULT(S): There was >50% reduction in the probability of conception during a menstrual cycle during which participants consumed alcohol. Caffeine consumption did not independently affect the probability of conception but may enhance alcohol's negative effect. Women who abstained from alcohol and consumed less than one cup of coffee or its equivalent per day conceived 26.9 pregnancies per 100 menstrual cycles compared with 10.5 per 100 menstrual cycles among those who consumed any alcohol and more than one cup of coffee per day. CONCLUSIONS: This study revealed an independent dose-related negative effect of alcohol consumption on the ability to conceive. Our results suggest that women who are attempting to conceive should abstain from consuming alcohol.

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Crossref · 10.1016/s0015-0282(98)00257-x

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Citations

Cites

Research works printed but not linked: 3

  1. Mello, 1983, Alcohol effects on estradiol in the female macaque, NIDA Res Monogr, 43, 210
  2. Gray, 1996, Ethylene glycol ethers and reproductive health in semiconductor workers, Occup Hyg, 2, 331
  3. O’Connor, 1988, Development of highly sensitive immunoassays to measure human chorionic gonadotropin, its β-subunit, and β core fragments in urine, Cancer Res, 48, 1361

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Metadata

Authors
Hakim, R. B., Gray, R. H., & Zacur, H.
Affiliations
Johns Hopkins University (US)
Corresponding author
Hakim, Rosemarie B
ORCID
Venue
Fertility and Sterility
Publisher
Elsevier BV
Published
1998-10
Volume
70
Issue
4
Pages
632-637
ISSN
0015-0282 (ISSN-L)
DOI
10.1016/s0015-0282(98)00257-x
OpenAlex
W2029365618
Cited by
205
References
39
Citations by year
2026: 3 · 2024: 5 · 2023: 5 · 2022: 7 · 2021: 8 · 2020: 59 · 2019: 7 · 2018: 7 · 2017: 10 · 2016: 13 · 2015: 11 · 2014: 4 · 2013: 10 · 2012: 8
FWCI
1.45
Type
journal article
Language
en
Open access
Licence
Locations
  • Fertility and Sterility (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5p30hd006268-28)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (5-P30-HD06268)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Keywords
alcohol consumption, caffeine consumption, coffee, female fertility, conception probability, menstrual cycle, dose-response relationship, women of reproductive age, human chorionic gonadotropin, steroid hormones
MeSH terms
Adult, Alcohol Drinking, Caffeine, Female, Fertility, Humans, Prospective Studies

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