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Cited by 367Prenatal Substance Exposure EffectsAlcohol Consumption and Health EffectsPregnancy and Medication Impact

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

ALCOHOL, SMOKING, AND INCIDENCE OF SPONTANEOUS ABORTIONS IN THE FIRST AND SECOND TRIMESTER

Harlap, S., Shiono, P.H.·1980·The Lancet
DOI 10.1016/s0140-6736(80)90061-6
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Abstract

32,019 women completed a questionnaire on alcohol use at their first antenatal visit; thereafter they were followed to assess the incidence of spontaneous abortions. 51.7% reported drinking no alcohol in early pregnancy; 44.7% had less than 1 drink daily; and 2.4, 0.4, and 0.1% had an average of 1-2, 3-5, or more than 6 drinks respectively. Life-table analysis showed that the age-adjusted relative risks of second-trimester losses (15-27 weeks) were 1.03 (not significant: ns), 1.98 (p < .01), and 3.53 (p < .01) for women taking less than 1, 1-2, and more than 3 drinks daily, compared with non-drinkers. The corresponding relative risks for first-trimester losses (5-14 weeks) were 1.12 (ns), 1.15(ns), and 1.15(ns). Smokers had relative risks of 1.01(ns) and 1.21(ns) in the first and second trimesters, compared with non-smokers. The increased risk of second-trimester miscarriage in drinkers was not explained by age, parity, race, marital status, smoking, or the number of previous spontaneous or induced abortions. Thus alcohol may harm human fetuses not only when it is abused but also when taken in moderation.

Overview

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Registry

Crossref · 10.1016/s0140-6736(80)90061-6

Cites

14 of 14 references verified0 citation errors · 0 not checkable

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Claims the paper makes

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Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Studies on sporadic miscarriage have shown associations with smoking, alcohol and caffeine.

    “Studies on sporadic miscarriage have shown associations with smoking, 25,158 alcohol 26,159 and caffeine.27,160,161”

    From Recurrent MiscarriageGreen‐top Guideline No. 17 (2023) · cites this paper as [159]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. Harlap, 1975, Characteristics of pregnant women reporting previous induced abortion, Bull WHO, 52, 149
  2. Chernoff, 1975, A mouse model of the fetal alcohol syndrome, Teratology, 11, 14A

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Metadata

Authors
Harlap, S., & Shiono, P. H.
Affiliations
Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
Venue
The Lancet
Publisher
Elsevier BV
Published
1980-07
Volume
316
Issue
8187
Pages
173-176
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/s0140-6736(80)90061-6
OpenAlex
W2054047398
Cited by
367
References
14
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 6 · 2017: 4 · 2016: 6 · 2015: 4 · 2014: 10 · 2013: 7 · 2012: 13
FWCI
24.31
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
Keywords
alcohol consumption in pregnancy, smoking during pregnancy, miscarriage, second-trimester pregnancy loss, early pregnancy loss, fetal alcohol effects, moderate drinking
MeSH terms
Abortion, Spontaneous, Adult, Alcohol Drinking, Ethanol, Black or African American, California, Education, Female, Fetus, Humans, Maternal-Fetal Exchange, Parity, Pregnancy, Pregnancy Trimester, First, Pregnancy Trimester, Second, Risk, Smoking, Black People, White People

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