The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.
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“glutamine has been confirmed to be a major nutrient source for oxidative metabolism in some cancer cell lines10–12”
From Glutamine reliance in cell metabolism (2020) · cites this paper as [12]
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Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
A Flexible System of Enzymatic Analysis
Lowry, O. H., & Passonneau, J. V. (1972) · Elsevier eBooks · doi:10.1016/b978-0-12-457950-7.x5001-3 · Cited by 4,050
Nutrition Needs of Mammalian Cells in Tissue Culture
Eagle, H. (1955) · Science · doi:10.1126/science.122.3168.501 · Cited by 1,619
Patterson, M. S., & Greene, R. C. (1965) · Analytical Chemistry · doi:10.1021/ac60226a017 · Cited by 1,459
Uptake and Metabolism of Plasma Glutamine by the Small Intestine
Windmueller, H. G., & Spaeth, A. E. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)42329-6 · Cited by 791
The Path of Carbon in Photosynthesis. V. Paper Chromatography and Radioautography of the Products1
Benson, A. A., Bassham, J. A., Calvin, M., Goodale, T. C., Haas, V. A., & Stepka, W. (1950) · Journal of the American Chemical Society · doi:10.1021/ja01160a080 · Cited by 479
The Use of Glucose-C14 for the Evaluation of the Pathways of Glucose Metabolism
Katz, J. J., & Wood, H. G. (1960) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64593-4 · Cited by 405
Alp, P. R., Newsholme, E. A., & Zammit, V. A. (1976) · Biochemical Journal · doi:10.1042/bj1540689 · Cited by 404
Uber den Stoffwechsel der Karzinomezellen
Warburg, O. (1924) · Medical Entomology and Zoology · Cited by 401
A new method for the determination of inulin in plasma and urine
Heyrovský, A. (1956) · Clinica Chimica Acta · doi:10.1016/0009-8981(56)90020-1 · Cited by 377
Research works printed but not linked: 8
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Cited by
Sorted by citations
Regulation of cancer cell metabolism
Cairns, R. A., Harris, I. S., & Mak, T. W. (2011) · Nature Reviews Cancer · doi:10.1038/nrc2981 · Cited by 4,744
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.002 · Cited by 4,088
Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation
Lunt, S. Y., & Vander Heiden, M. G. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154237 · Cited by 3,057
DeBerardinis, R. J., Mancuso, A., Daikhin, E., Nissim, I., Yudkoff, M., Wehrli, S., & Thompson, C. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709747104 · Cited by 2,622
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chang, C.-H., Curtis, J. D., Maggi, L. B., Faubert, B., Villarino, A. V., O’Sullivan, D., Huang, S. C.-C., van der Windt, G. J. W., Blagih, J., Qiu, J., et al. (2013) · Cell · doi:10.1016/j.cell.2013.05.016 · Cited by 2,204
Metadata
- Authors
- Reitzer, L. J., Wice, B. M., & Kennell, D.
- Affiliations
- Washington University in St. Louis (US)
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1979-04
- Volume
- 254
- Issue
- 8
- Pages
- 2669-2676
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1483212110
- Cited by
- 1,240
- References
- 39
- Citations by year
- 2026: 14 · 2025: 19 · 2024: 30 · 2023: 40 · 2022: 24 · 2021: 45 · 2020: 31 · 2019: 28 · 2018: 42 · 2017: 42 · 2016: 38 · 2015: 38 · 2014: 48 · 2013: 36 · 2012: 46
- FWCI
- 12.54
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Biological Chemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- American Cancer Society
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Hypoxia, and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- glutamine, glucose, energy metabolism, HeLa cells, cultured cells, energy sources
- MeSH terms
- Adenosine Diphosphate, Adenosine Triphosphate, Citric Acid Cycle, Fructose, Galactose, Glucose, Glutamine, HeLa Cells, Humans, Kinetics, Lactates, Pentoses
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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