Cited by 1,619Viral Infectious Diseases and Gene Expression in InsectsCancer and biochemical researchCellular Mechanics and Interactions

Nutrition Needs of Mammalian Cells in Tissue Culture

Eagle, Harry·1955·Science

Abstract

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Integrity signals

Registry

Crossref · 10.1126/science.122.3168.501

Cites

10 of 10 references verified0 citation errors · 0 not checkable

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  • Glutamine is a major nutrient source for oxidative metabolism in some cancer cell lines.

    “glutamine has been confirmed to be a major nutrient source for oxidative metabolism in some cancer cell lines10–12”

    From Glutamine reliance in cell metabolism (2020) · cites this paper as [10]

  • Glutamine supplementation is necessary for the growth and viability of many cultured cell lines, particularly cancer cell lines.

    “While glutamine can be synthesized directly by most mammalian cells, it has been recognized for several decades that glutamine supplementation is necessary for the growth and viability of many cultured cell lines, particularly cancer cell lines (72, 75, 76).”

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Authors
Eagle, H.
Affiliations
National Institutes of Health (US)
Corresponding author
Eagle, Harry
Venue
Science
Published
1955-09-16
Volume
122
Issue
3168
Pages
501-504
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2053387982
Cited by
1,619
References
10
Citations by year
2026: 36 · 2025: 37 · 2024: 35 · 2023: 42 · 2022: 44 · 2021: 56 · 2020: 44 · 2019: 34 · 2018: 36 · 2017: 34 · 2016: 27 · 2015: 26 · 2014: 37 · 2013: 23 · 2012: 33
FWCI
22.00
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Viral Infectious Diseases and Gene Expression in Insects
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cancer and biochemical research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
Keywords
tissue culture, cell growth requirements, cell culture media
MeSH terms
Health Services Needs and Demand, Research Design, Tissue Culture Techniques

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