Cited by 558Congenital heart defects researchDevelopmental Biology and Gene RegulationGenomics and Chromatin Dynamics

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

Open access

Laverriere, A.C., MacNeill, C., Mueller, C., Poelmann, R.E., Burch, J.B., Evans, T.·1994·Journal of Biological Chemistry

DOI 10.1016/s0021-9258(17)31636-8

Open this paper in CoChat — free account

Abstract

We describe experiments which show that: 1) two previously identified members of the GATA family of transcription factors (both of which were originally called GATA-4) correspond to chicken cDNAs for two distinct factors (which we now refer to as cGATA-4 and cGATA-5); 2) another new member of this family corresponds to a third factor designated cGATA-6; 3) each of these mRNAs displays a differential expression pattern. The cGATA-5 gene is initially transcribed in the cardiac crescent prior to formation of the primordial heart tube. Following formation of the primitive heart, cGATA-5 transcripts are evident in both endocardium and myocardium as well as in other lateral plate derivatives. The cGATA-5 gene is also transcribed in the primitive embryonic gut and in late stage embryos is sequentially up-regulated in distinct segments of gastrointestinal epithelia as they undergo terminal differentiation. These studies thus provide novel insights into tissue-specific regulation by GATA-5, as well as into possibly overlapping regulatory functions for these three family members.

Integrity signals

Registry

Crossref · 10.1016/s0021-9258(17)31636-8

Cites

42 of 42 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Molecular Cloning. A Laboratory Manual
Wood, E. (1983) · Biochemical Education · doi:10.1016/0307-4412(83)90068-7 · Cited by 29,534
A series of normal stages in the development of the chick embryo
Hamburger, V., & Hamilton, H. L. (1951) · Journal of Morphology · doi:10.1002/jmor.1050880104 · Cited by 12,254
Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.
Frohman, M. A., Dush, M. K., & Martin, G. R. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.23.8998 · Cited by 4,554
Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.
Grunstein, M. R., & Hogness, D. S. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.10.3961 · Cited by 3,386
Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine V. Unitarian theory of the origin of the four epithelial cell types
Cheng, H., & Leblond, C. P. (1974) · American Journal of Anatomy · doi:10.1002/aja.1001410407 · Cited by 1,737
Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes
Cox, K. H., DeLeon, D. V., Angerer, L. M., & Angerer, R. C. (1984) · Developmental Biology · doi:10.1016/0012-1606(84)90162-3 · Cited by 1,610
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
Pevny, L., Simon, M. C., Robertson, E., Klein, W. H., Tsai, S.-F., D'Agati, V., Orkin, S. H., & Costantini, F. (1991) · Nature · doi:10.1038/349257a0 · Cited by 1,308
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells
Tsai, S., Martin, D. I. K., Zon, L. I., D’Andrea, A. D., Wong, G. G., & Orkin, S. H. (1989) · Nature · doi:10.1038/339446a0 · Cited by 884
GATA-binding transcription factors in hematopoietic cells
Orkin, S. (1992) · Blood · doi:10.1182/blood.v80.3.575.575 · Cited by 884

Show all 42 references

Research works printed but not linked: 7

Cunningham, 1991, Mol. Cell. Biol., 11, 6205
Spieth, 1991, Mol. Cell. Biol., 11, 4651
Ko, 1993, Mol. Cell. Biol., 13, 4011
Merika, 1993, Mol. Cell. Biol., 13, 3999
Arceci, 1993, Mol. Cell. Biol., 13, 2235
Grant, 1993, Mol. Cell. Biol., 13, 4186
Parmacek, 1992, Mol. Cell. Biol., 12, 1967

Sorted by citations

Items 101–200 of 554

Specification of embryonic axis and mosaic development in ascidians
Nishida, H. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20469 · Cited by 158
The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila
Gajewski, K. M., Fossett, N., Molkentin, J. D., & Schulz, R. A. (1999) · Development · doi:10.1242/dev.126.24.5679 · Cited by 153
Role of SCL/Tal-1, GATA, and Ets transcription factor binding sites for the regulation of Flk-1 expression during murine vascular development
Kappel, A., Schlaeger, T. M., Flamme, I., Orkin, S. H., Risau, W., & Breier, G. (2000) · Blood · doi:10.1182/blood.v96.9.3078 · Cited by 151
A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart
McFadden, D. G., Charité, J., Richardson, J. A., Srivastava, D., Firulli, A. B., & Olson, E. N. (2000) · Development · doi:10.1242/dev.127.24.5331 · Cited by 149
Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis
Brown, D. D., Martz, S. N., Binder, O., Goetz, S. C., Price, B. M. J., Smith, J. C., & Conlon, F. L. (2005) · Development · doi:10.1242/dev.01596 · Cited by 149
GATA-4 Activates Transcription Via Two Novel Domains That Are Conserved within the GATA-4/5/6 Subfamily
Morrisey, E. E., Ip, H. S., Tang, Z., & Parmacek, M. S. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.13.8515 · Cited by 145
The Transcriptional Activator Hepatocyte Nuclear Factor 6 Regulates Liver Gene Expression
Samadani, U., & Costa, R. H. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.11.6273 · Cited by 144
Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1
Malik, T. H., Shoichet, S. A., Latham, P., Kroll, T. G., Peters, L. L., & Shivdasani, R. A. (2001) · The EMBO Journal · doi:10.1093/emboj/20.7.1715 · Cited by 141
Activation of the Interleukin-5 Promoter by cAMP in Murine EL-4 Cells Requires the GATA-3 and CLE0 Elements
Siegel, M. D., Zhang, D.-H., Ray, P., & Ray, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.41.24548 · Cited by 138
Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA‐2 in urogenital development
Zhou, Y., Lim, K., Onodera, K., Takahashi, S., Ohta, J., Minegishi, N., Tsai, F., Orkin, S. H., Yamamoto, M., & Engel, J. D. (1998) · The EMBO Journal · doi:10.1093/emboj/17.22.6689 · Cited by 139
Gotta have GATA
Simon, M. C. (1995) · Nature Genetics · doi:10.1038/ng0995-9 · Cited by 137
Nitrogen metabolite signalling involves the C‐terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3′ untranslated region of its mRNA.
Platt, A., Langdon, T., Arst, H. N., Kirk, D., Tollervey, D. W., Sanchez, J. M., & Caddick, M. X. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00639.x · Cited by 137
Patterns of expression in the developing myocardium: towards a morphologically integrated transcriptional model
Franco, D. (1998) · Cardiovascular Research · doi:10.1016/s0008-6363(97)00321-0 · Cited by 132
N-Cadherin–Catenin Interaction: Necessary Component of Cardiac Cell Compartmentalization during Early Vertebrate Heart Development
Linask, K. K., Knudsen, K. A., & Gui, Y. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8570 · Cited by 134
The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development
Keijzer, R., van Tuyl, M., Meijers, C., Post, M., Tibboel, D., Grosveld, F. G., & Koutsourakis, M. (2001) · Development · doi:10.1242/dev.128.4.503 · Cited by 131
Acetylation of GATA-4 Is Involved in the Differentiation of Embryonic Stem Cells into Cardiac Myocytes
Kawamura, T., Ono, K., Morimoto, T., Wada, H., Hirai, M., Hidaka, K., Morisaki, T., Heike, T., Nakahata, T., Kita, T., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m412428200 · Cited by 130
Abnormalities of the Genitourinary Tract in Female Mice Lacking GATA5
Molkentin, J. D., Tymitz, K. M., Richardson, J. A., & Olson, E. N. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.14.5256-5260.2000 · Cited by 128
GATA-6 and Thyroid Transcription Factor-1 Directly Interact and Regulate Surfactant Protein-C Gene Expression
Liu, C., Glasser, S. W., Wan, H., & Whitsett, J. A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107585200 · Cited by 129
Transcription Factors GATA-4 and GATA-6 and a GATA Family Cofactor, FOG-2, Are Expressed in Human Ovary and Sex Cord-Derived Ovarian Tumors
Laitinen, M., Anttonen, M., Ketola, I., Wilson, D. B., Ritvos, O., Bützow, R. C., & Heikinheimo, M. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.9.6828 · Cited by 127
Interleukin-18 Is a Pro-hypertrophic Cytokine That Acts through a Phosphatidylinositol 3-Kinase-Phosphoinositide-dependent Kinase-1-Akt-GATA4 Signaling Pathway in Cardiomyocytes
Chandrasekar, B., Mummidi, S., Claycomb, W. C., Mestril, R., & Nemer, M. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411787200 · Cited by 125
Cardiomyocyte differentiation by GATA-4-deficient embryonic stem cells
Narita, N., Bielińska, M., & Wilson, D. B. (1997) · Development · doi:10.1242/dev.124.19.3755 · Cited by 124
A role for GATA5 in Xenopus endoderm specification
Weber, H., Symes, C. E., Walmsley, M. E., Rodaway, A., & Patient, R. K. (2000) · Development · doi:10.1242/dev.127.20.4345 · Cited by 121
Regulation of GATA gene expression during vertebrate development
Burch, J. B. E. (2004) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2004.10.002 · Cited by 120
Self-citation
A Functionally Conserved N-terminal Domain of the Friend of GATA-2 (FOG-2) Protein Represses GATA4-Dependent Transcription
Svensson, E. C., Huggins, G. S., Dardik, F. B., Polk, C. E., & Leiden, J. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001522200 · Cited by 119
Arabidopsis thaliana GATA factors: organisation, expression and DNA-binding characteristics
Teakle, G. R., Manfield, I. W., Graham, J. F., & Gilmartin, P. M. (2002) · Plant Molecular Biology · doi:10.1023/a:1016062325584 · Cited by 119
A GATA-6 gene heart-region-specific enhancer provides a novel means to mark and probe a discrete component of the mouse cardiac conduction system
Davis, D. L., Edwards, A. V., Juraszek, A. L., Phelps, A. L., Wessels, A., & Burch, J. B. E. (2001) · Mechanisms of Development · doi:10.1016/s0925-4773(01)00500-7 · Cited by 119
Self-citation
Deletion of the GATA Domain of TRPS1 Causes an Absence of Facial Hair and Provides New Insights into the Bone Disorder in Inherited Tricho-Rhino-Phalangeal Syndromes
Malik, T. H., Stechow, D. V., Bronson, R. T., & Shivdasani, R. A. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.24.8592-8600.2002 · Cited by 116
Direct Activation of a GATA6 Cardiac Enhancer by Nkx2.5: Evidence for a Reinforcing Regulatory Network of Nkx2.5 and GATA Transcription Factors in the Developing Heart
Molkentin, J. D., Antos, C. L., Mercer, B. M., Taigen, T. L., Miano, J. M., & Olson, E. N. (2000) · Developmental Biology · doi:10.1006/dbio.1999.9544 · Cited by 116
A Triad of Serum Response Factor and the GATA and NK Families Governs the Transcription of Smooth and Cardiac Muscle Genes
Nishida, W., Nakamura, M., Mori, S., Takahashi, M. P., Ohkawa, Y., Tadokoro, S., Yoshida, K., Hiwada, K., Hayashi, K., & Sobue, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111824200 · Cited by 115
GATA-6 Induces p21Cip1 Expression and G1Cell Cycle Arrest
Perlman, H., Suzuki, E., Simonson, M. S., Smith, R. C., & Walsh, K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.22.13713 · Cited by 114
Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1α
Krasinski, S. D., van Wering, H. M., Tannemaat, M. R., & Grand, R. J. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.1.g69 · Cited by 114
A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer
Perez‐Stable, C., Pozas, A. D. L., & Roos, B. A. (2000) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00300-2 · Cited by 111
Over‐expression of GATA‐6 in Xenopus embryos blocks differentiation of heart precursors
Gove, C. D., Walmsley, M., Nijjar, S., Bertwistle, D., Guille, M., Partington, G., Bomford, A. B., & Patient, R. K. (1997) · The EMBO Journal · doi:10.1093/emboj/16.2.355 · Cited by 110
Distinct 5′ SCL Enhancers Direct Transcription to Developing Brain, Spinal Cord, and Endothelium: Neural Expression Is Mediated by GATA Factor Binding Sites
Sinclair, A. M., Göttgens, B., Barton, L. M., Stanley, M. L., Pardanaud, L., Klaine, M., Gering, M., Bahn, S., Sánchez, M. J., Bench, A. J., et al. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9236 · Cited by 105
Anatomy of a blastocyst: Cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo
Schrode, N., Xenopoulos, P., Piliszek, A., Frankenberg, S., Płusa, B., & Hadjantonakis, A. (2013) · genesis · doi:10.1002/dvg.22368 · Cited by 107
Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells
Capo‐chichi, C. D., Rula, M. E., Smedberg, J. L., Vanderveer, L., Parmacek, M. S., Morrisey, E. E., Godwin, A. K., & Xu, X. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.07.037 · Cited by 106
Myocyte Enhancer Binding Factor-2 Expression and Activity in Vascular Smooth Muscle Cells
Firulli, A. B., Miano, J. M., Bi, W., Johnson, A. D., Casscells, W., Olson, E. N., & Schwarz, J. J. (1996) · Circulation Research · doi:10.1161/01.res.78.2.196 · Cited by 105
Stem Cell Chromatin Patterns: An Instructive Mechanism for DNA Hypermethylation?
Ohm, J. E., & Baylin, S. B. (2007) · Cell Cycle · doi:10.4161/cc.6.9.4210 · Cited by 102
hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation
Holmes, M. L., Turner, J. J. O., Fox, A. H., Chisholm, O., Crossley, M., & Chong, B. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23491 · Cited by 102
Hepatic Erythropoietin Gene Regulation by GATA-4
Dame, C., Sola, M. C., Lim, K.-C., Leach, K. M., Fandrey, J., Ma, Y., Knöpfle, G., Engel, J. D., & Bungert, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310404200 · Cited by 99
A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells.
Poll, A. V., Pierreux, C., Lokmane, L., Haumaître, C., Achouri, Y., Jacquemin, P., Rousseau, G., Cereghini, S., & Lemaigre, F. (2006) · Diabetes · doi:10.2337/diabetes.55.01.06.db05-0681 · Cited by 104
Cooperative interaction between GATA5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells
Nemer, G. M., & Nemer, M. J. (2002) · Development · doi:10.1242/dev.129.17.4045 · Cited by 100
The molecular mechanisms of cardiac development and related diseases
Li, Y., Du, J., Deng, S., Liu, B., Jing, X., Yan, Y., Liu, Y., Wang, J., Zhou, X., & She, Q. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02069-8 · Cited by 108
Cooperative Interaction between Hepatocyte Nuclear Factor 4 α and GATA Transcription Factors Regulates ATP-Binding Cassette Sterol Transporters ABCG5 and ABCG8
Sumi, K., Tanaka, T., Uchida, A., Magoori, K., Urashima, Y., Ohashi, R., Ohguchi, H., Okamura, M., Kudo, H., Daigo, K., et al. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01894-06 · Cited by 98
Retinoid Signaling Required for Normal Heart Development Regulates GATA-4 in a Pathway Distinct from Cardiomyocyte Differentiation
Kostetskii, I., Jiang, Y., Kostetskaia, E., Yuan, S., Evans, T., & Zile, M. H. (1999) · Developmental Biology · doi:10.1006/dbio.1998.9139 · Cited by 98
Self-citation
Gata factor Pannier is required to establish competence for heart progenitor formation
Klinedinst, S., & Bodmer, R. (2003) · Development · doi:10.1242/dev.00517 · Cited by 98
Regulation of Metallothionein Gene Transcription
Moilanen, L. H., Fukushige, T., & Freedman, J. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.29655 · Cited by 97
p300 Protein as a Coactivator of GATA-5 in the Transcription of Cardiac-restricted Atrial Natriuretic Factor Gene
Kakita, T., Hasegawa, K., Morimoto, T., Kaburagi, S., Wada, H., & Sasayama, S. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.48.34096 · Cited by 96
Combinatorial regulation of tissue specification by GATA and FOG factors
Chlon, T. M., & Crispino, J. D. (2012) · Development · doi:10.1242/dev.080440 · Cited by 103
Key Residues Characteristic of GATA N-fingers Are Recognized By FOG
Fox, A. H., Kowalski, K., King, G. F., Mackay, J. P., & Crossley, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.50.33595 · Cited by 96
GATA-6 Activates Transcription of Surfactant Protein A
Bruno, M. D., Korfhagen, T. R., Liu, C., Morrisey, E. E., & Whitsett, J. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.2.1043 · Cited by 95
FOG acts as a repressor of red blood cell development inXenopus
Deconinck, A. E., Mead, P. E., Tevosian, S. G., Crispino, J. D., Katz, S. G., Zon, L. I., & Orkin, S. H. (2000) · Development · doi:10.1242/dev.127.10.2031 · Cited by 95
Beta-Catenin Signaling in Hepatic Development and Progenitors: Which Way Does the WNT Blow?
Lade, A. G., & Monga, S. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22522 · Cited by 90
Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation
Watamoto, K., Towatari, M., Ozawa, Y., Miyata, Y., Okamoto, M., Abe, A., Naoe, T., & Saito, H. (2003) · Oncogene · doi:10.1038/sj.onc.1206902 · Cited by 95
Expression of zebrafish GATA 3 (gta3) during gastrulation and neurulation suggests a role in the specification of cell fate
Neave, B., Rodaway, A., Wilson, S. W., Patient, R. K., & Holder, N. (1995) · Mechanisms of Development · doi:10.1016/0925-4773(95)00351-7 · Cited by 93
Differential roles of GATA‐1 and GATA‐2 in growth and differentiation of mast cells
Harigae, H., Takahashi, S., Suwabe, N., Ohtsu, H., Gu, L., Yang, Z., Tsai, F., Kitamura, Y., Engel, J. D., & Yamamoto, M. P. (1998) · Genes to Cells · doi:10.1046/j.1365-2443.1998.00166.x · Cited by 92
Localization of Distant Urogenital System-, Central Nervous System-, and Endocardium-Specific Transcriptional Regulatory Elements in the GATA-3 Locus
Lakshmanan, G., Lieuw, K. H., Lim, K.-C., Gu, Y., Grosveld, F. G., Engel, J. D., & Karis, A. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.2.1558 · Cited by 92
Gata4 and Gata5 Cooperatively Regulate Cardiac Myocyte Proliferation in Mice
Singh, M. K., Li, Y., Li, S., Cobb, R. M., Zhou, D. D., Lu, M. M., Epstein, J. A., Morrisey, E. E., & Gruber, P. J. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.038539 · Cited by 91
Regulation of the rat cardiac troponin I gene by the transcription factor GATA-4
Murphy, A. M., Thompson, W. R., Ling Fan, P. E. N. G., & Jones, L. (1997) · Biochemical Journal · doi:10.1042/bj3220393 · Cited by 91
Gata2 and Gata3: novel markers for early embryonic polarity and for non-neural ectoderm in the chick embryo
Sheng, G., & Stern, C. D. (1999) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00150-1 · Cited by 91
The Gene Encoding the Mitogen-responsive Phosphoprotein Dab2 Is Differentially Regulated by GATA-6 and GATA-4 in the Visceral Endoderm
Morrisey, E. E., Musco, S., Chen, M. Y. Z., Lu, M. M., Leiden, J. M., & Parmacek, M. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001331200 · Cited by 76
GATA factor switching from GATA 2 to GATA 1 contributes to erythroid differentiation
Suzuki, M., Kobayashi‐Osaki, M., Tsutsumi, S., Pan, X., Ohmori, S., Takai, J., Moriguchi, T., Ohneda, O., Ohneda, K., Shimizu, R., et al. (2013) · Genes to Cells · doi:10.1111/gtc.12086 · Cited by 98
Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins
Yamagata, T., Nishida, J., Sakai, R., Tanaka, T., Honda, H., Hirano, N., Mano, H., Yazaki, Y., & Hirai, H. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.7.3830 · Cited by 103
Reciprocal Changes in the Expression of Transcription Factors GATA-4 and GATA-6 Accompany Adrenocortical Tumorigenesis in Mice and Humans
Kiiveri, S., Siltanen, S., Rahman, N. A., Bielińska, M., Lehto, V., Huhtaniemi, I. T., Muglia, L. J., Wilson, D. B., & Heikinheimo, M. (1999) · Molecular Medicine · doi:10.1007/bf03403542 · Cited by 88
Muscle and nerve-specific regulation of a novel NK-2 class homeodomain factor in Caenorhabditis elegans
Harfe, B. D., & Fire, A. Z. (1998) · Development · doi:10.1242/dev.125.3.421 · Cited by 87
Combinatorial interactions regulating cardiac transcription
Durocher, D., & Nemer, M. J. (1998) · Developmental Genetics · doi:10.1002/(sici)1520-6408(1998)22:3 · Cited by 101
Isolation and characterization of a new gene, sre, which encodes a GATA-type regulatory protein that controls iron transport in Neurospora crassa
Zhou, L., Haas, H., & Marzluf, G. A. (1998) · Molecular and General Genetics MGG · doi:10.1007/s004380050845 · Cited by 86
A p300 Protein as a Coactivator of GATA-6 in the Transcription of the Smooth Muscle-Myosin Heavy Chain Gene
Wada, H., Hasegawa, K., Morimoto, T., Kakita, T., Yanazume, T., & Sasayama, S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000828200 · Cited by 85
elt-2, a Second GATA Factor from the Nematode Caenorhabditis elegans
Hawkins, M. G., & McGhee, J. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.24.14666 · Cited by 84
Structure and Specificity of GATA Proteins in Th2 Development
Ranganath, S. H., & MURPHY, K. M. M. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.8.2716-2725.2001 · Cited by 82
GATA Factors Are Essential for Activity of the Neuron-Specific Enhancer of the Gonadotropin-Releasing Hormone Gene
Lawson, M. A., Whyte, D. B., & Mellon, P. L. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.7.3596 · Cited by 82
The N‐terminal fingers of chicken GATA‐2 and GATA–3 are independent sequence‐specific DNA binding domains
Pedone, P. V., Omichinski, J. G., Nony, P., Trainor, C. D., Gronenborn, A. M., Clore, G. M., & Felsenfeld, G. (1997) · The EMBO Journal · doi:10.1093/emboj/16.10.2874 · Cited by 80
Erythropoiesis and vasculogenesis in embryoid bodies lacking visceral yolk sac endoderm
Bielińska, M., Narita, N., Heikinheimo, M., Porter, S., & Wilson, D. B. (1996) · Blood · doi:10.1182/blood.v88.10.3720.bloodjournal88103720 · Cited by 83
Cutting Edge: Identification of an Alternative GATA-3 Promoter Directing Tissue-Specific Gene Expression in Mouse and Human
Asnagli, H., Afkarian, M., & MURPHY, K. M. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.9.4268 · Cited by 82
Gln3p Nuclear Localization and Interaction with Ure2p inSaccharomyces cerevisiae
Kulkarni, A. A., Abulhamd, A., Rai, R., el Berry, H. M., & Cooper, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104580200 · Cited by 82
Cellular and Molecular Basis of Liver Development
Shin, D., & Monga, S. P. (2013) · Comprehensive physiology · doi:10.1002/cphy.c120022 · Cited by 95
Physical Interaction between GATA-5 and Hepatocyte Nuclear Factor-1α Results in Synergistic Activation of the Human Lactase-Phlorizin Hydrolase Promoter
van Wering, H. M., Huibregtse, I. L., van der Zwan, S. M., de Bie, M. S., Dowling, L. N., Boudreau, F., Rings, E. H. H. M., Grand, R. J., & Krasinski, S. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203645200 · Cited by 80
Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies
Caramori, G., Lim, S., Ito, K., Tomita, K., Oates, T., Jazrawi, E., Chung, K. F., Barnes, P. J., & Adcock, I. M. (2001) · European Respiratory Journal · doi:10.1183/09031936.01.00040701 · Cited by 78
Friend of GATA (FOG)-1 and FOG-2 Differentially Repress the GATA-Dependent Activity of Multiple Gonadal Promoters
Robert, N. M., Tremblay, J., & Viger, R. S. (2002) · Endocrinology · doi:10.1210/en.2002-220280 · Cited by 78
Vertebrate heart development
Lyons, G. E. (1996) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(96)80067-0 · Cited by 78
TheXenopushomologue ofBicaudal-Cis a localized maternal mRNA that can induce endoderm formation
Wessely, O., & Robertis, E. M. D. (2000) · Development · doi:10.1242/dev.127.10.2053 · Cited by 75
Spectroscopic and Functional Determination of the Interaction of Pb2+with GATA Proteins
Ghering, A. B., Jenkins, L. M. M., Schenck, B. L., Deo, S., Mayer, R. A., Pikaart, M. J., Omichinski, J. G., & Godwin, H. A. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0464544 · Cited by 77
Generation of mice harbouring a conditional loss-of-function allele of Gata6
Sodhi, C. P., Li, J., & Duncan, S. A. (2006) · BMC Developmental Biology · doi:10.1186/1471-213x-6-19 · Cited by 75
Purkinje Fibers of the Avian Heart Express a Myogenic Transcription Factor Program Distinct from Cardiac and Skeletal Muscle
Takebayashi‐Suzuki, K., Pauliks, L. B., Eltsefon, Y., & Mikawa, T. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0270 · Cited by 75
GATA-6 is required for maturation of the lung in late gestation
Liu, C., Morrisey, E. E., & Whitsett, J. A. (2002) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00044.2002 · Cited by 75
Repressive and restrictive mesodermal interactions with gut endoderm: possible relation to Meckel’s Diverticulum
Bossard, P., & Zaret, K. S. (2000) · Development · doi:10.1242/dev.127.22.4915 · Cited by 75
GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene
Kobayashi‐Osaki, M., Ohneda, O., Suzuki, N., Minegishi, N., Yokomizo, T., Takahashi, S., Lim, K.-C., Engel, J. D., & Yamamoto, M. P. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.16.7005-7020.2005 · Cited by 75
SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chickNkx2.5enhancer
Lee, K., Evans, S., Ruan, T. Y., & Lassar, A. B. (2004) · Development · doi:10.1242/dev.01344 · Cited by 75
An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer
Sulahian, R., Casey, F., Shen, J., Qian, Z., Shin, H., Ogino, S., Weir, B. A., Vázquez, F., Liu, X. S., Hahn, W. C., et al. (2013) · Oncogene · doi:10.1038/onc.2013.517 · Cited by 78
A Role for GATA-4/5/6 in the Regulation of Nkx2.5 Expression with Implications for Patterning of the Precardiac Field
Jiang, Y., Drysdale, T. A., & Evans, T. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9469 · Cited by 74
Self-citation
Function of GATA Transcription Factors in Induction of Endothelial Vascular Cell Adhesion Molecule-1 by Tumor Necrosis Factor-α
Umetani, M., Mataki, C., Minegishi, N., Yamamoto, M. P., Hamakubo, T., & Kodama, T. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.21.6.917 · Cited by 74
GATA-4 and GATA-6 Transcription Factors: Expression, Immunohistochemical Localization, and Possible Function in the Porcine Ovary1
Gillio‐Meina, C., Hui, Y. Y., & LaVoie, H. A. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.009092 · Cited by 74
Regulation of Cardiac Gene Expression by GATA-4/5/6
Evans, T. (1997) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(97)00010-8 · Cited by 74
Self-citation
An Alternate Promoter Directs Expression of a Truncated, Muscle-specific Isoform of the Human Ankyrin 1 Gene
Gallagher, P. G., & Forget, B. G. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.3.1339 · Cited by 73
The Human and Mouse GATA-6 Genes Utilize Two Promoters and Two Initiation Codons
Brewer, A. C., Gove, C. D., Davies, A., McNulty, C., Barrow, D., Koutsourakis, M., Farzaneh, F., Pizzey, J. A., Bomford, A. B., & Patient, R. K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.53.38004 · Cited by 72
Nkx2.5‐negative myocardium of the posterior heart field and its correlation with podoplanin expression in cells from the developing cardiac pacemaking and conduction system
Groot, A. C. G., Mahtab, E. A. F., Hahurij, N. D., Wisse, L. J., DeRuiter, M. C., WIJFFELS, M. C. E. F., & Poelmann, R. E. (2007) · The Anatomical Record · doi:10.1002/ar.20406 · Cited by 72
Self-citation
Signal transduction in early heart development (I): cardiogenic induction and heart tube formation.
Wagner, M. A., & Siddiqui, M. A. Q. (2007) · PubMed · Cited by 68
Genomic and epigenomic heterogeneity in molecular subtypes of gastric cancer
Lim, B. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i3.1190 · Cited by 72
GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1α
Divine, J. K., Staloch, L. J., Haveri, H., Jacobsen, C. M., Wilson, D. B., Heikinheimo, M., & Simon, T. C. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00421.2003 · Cited by 71
GATA‐1: Friends, Brothers, and Coworkers
Morceau, F., Schnekenburger, M., Dicato, M. A., & Diederich, M. F. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1329.064 · Cited by 72

Authors: Laverriere, A. C., MacNeill, C., Mueller, C., Poelmann, R. E., Burch, J. B., & Evans, T.
Affiliations: Fox Chase Cancer Center (US)
ORCID: Poelmann, R.E.
Evans, T.
Venue: Journal of Biological Chemistry
Publisher: Elsevier BV
Published: 1994-09
Volume: 269
Issue: 37
Pages: 23177-23184
ISSN: 0021-9258 (ISSN-L)
DOI: 10.1016/s0021-9258(17)31636-8
OpenAlex: W1577509897
Cited by: 558
References: 42
Citations by year: 2025: 2 · 2024: 10 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 4 · 2019: 11 · 2018: 12 · 2017: 8 · 2016: 8 · 2015: 11 · 2014: 8 · 2013: 12 · 2012: 11
FWCI: 10.50
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by/4.0/ (vor, 9550 d)
Locations: Journal of Biological Chemistry (publishedVersion, cc-by)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k11ca001689-02)
U.S. Public Health Service (35535)
National Cancer Institute (CA-01689, P30CA006927, CA06927)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Keywords: GATA4, GATA5, GATA6, GATA transcription factors, heart development, intestinal development, endocardium, myocardium, lateral plate mesoderm, gastrointestinal epithelium, gene expression regulation, chick embryo, cDNA cloning
MeSH terms: Animals, Base Sequence, Cell Differentiation, Chick Embryo, Chickens, Digestive System, DNA-Binding Proteins, Epithelial Cells, Epithelium, Heart, Mesoderm, Molecular Sequence Data, Myocardium, Transcription Factors, Transcription, Genetic, Sequence Homology, Amino Acid, DNA, Complementary, GATA4 Transcription Factor, GATA5 Transcription Factor, GATA6 Transcription Factor

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks