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Cited by 558Congenital heart defects researchDevelopmental Biology and Gene RegulationGenomics and Chromatin Dynamics

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

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Laverriere, A.C., MacNeill, C., Mueller, C., Poelmann, R.E., Burch, J.B., Evans, T.·1994·Journal of Biological Chemistry
DOI 10.1016/s0021-9258(17)31636-8
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Abstract

We describe experiments which show that: 1) two previously identified members of the GATA family of transcription factors (both of which were originally called GATA-4) correspond to chicken cDNAs for two distinct factors (which we now refer to as cGATA-4 and cGATA-5); 2) another new member of this family corresponds to a third factor designated cGATA-6; 3) each of these mRNAs displays a differential expression pattern. The cGATA-5 gene is initially transcribed in the cardiac crescent prior to formation of the primordial heart tube. Following formation of the primitive heart, cGATA-5 transcripts are evident in both endocardium and myocardium as well as in other lateral plate derivatives. The cGATA-5 gene is also transcribed in the primitive embryonic gut and in late stage embryos is sequentially up-regulated in distinct segments of gastrointestinal epithelia as they undergo terminal differentiation. These studies thus provide novel insights into tissue-specific regulation by GATA-5, as well as into possibly overlapping regulatory functions for these three family members.

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Crossref · 10.1016/s0021-9258(17)31636-8

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42 of 42 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 7

  1. Cunningham, 1991, Mol. Cell. Biol., 11, 6205
  2. Spieth, 1991, Mol. Cell. Biol., 11, 4651
  3. Ko, 1993, Mol. Cell. Biol., 13, 4011
  4. Merika, 1993, Mol. Cell. Biol., 13, 3999
  5. Arceci, 1993, Mol. Cell. Biol., 13, 2235
  6. Grant, 1993, Mol. Cell. Biol., 13, 4186
  7. Parmacek, 1992, Mol. Cell. Biol., 12, 1967

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Metadata

Authors
Laverriere, A. C., MacNeill, C., Mueller, C., Poelmann, R. E., Burch, J. B., & Evans, T.
Affiliations
Fox Chase Cancer Center (US)
ORCID
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1994-09
Volume
269
Issue
37
Pages
23177-23184
ISSN
0021-9258 (ISSN-L)
DOI
10.1016/s0021-9258(17)31636-8
OpenAlex
W1577509897
Cited by
558
References
42
Citations by year
2025: 2 · 2024: 10 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 4 · 2019: 11 · 2018: 12 · 2017: 8 · 2016: 8 · 2015: 11 · 2014: 8 · 2013: 12 · 2012: 11
FWCI
10.50
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Biological Chemistry (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5k11ca001689-02)
  • U.S. Public Health Service (35535)
  • National Cancer Institute (CA-01689, P30CA006927, CA06927)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Keywords
GATA4, GATA5, GATA6, GATA transcription factors, heart development, intestinal development, endocardium, myocardium, lateral plate mesoderm, gastrointestinal epithelium, gene expression regulation, chick embryo, cDNA cloning
MeSH terms
Animals, Base Sequence, Cell Differentiation, Chick Embryo, Chickens, Digestive System, DNA-Binding Proteins, Epithelial Cells, Epithelium, Heart, Mesoderm, Molecular Sequence Data, Myocardium, Transcription Factors, Transcription, Genetic, Sequence Homology, Amino Acid, DNA, Complementary, GATA4 Transcription Factor, GATA5 Transcription Factor, GATA6 Transcription Factor

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