The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Structural evidence for methionine at the reactive site of human alpha-1-proteinase inhibitor.
Open accessAbstract
An unadecapeptide, obtained by papain digestion of denatured human alpha-1-proteinase inhibitor (alpha-1-PI), has been isolated and sequenced. The structure of this fragment overlaps with the NH2-terminal sequence of modified inhibitor (alpha-1-PI) prepared from dissociated complexes of alpha-1-PI with trypsin, chymotrypsin, and elastase. Furthermore, structural homology with the reactive centers of proteinase inhibitors from other sources is readily detectable. Methionine has been found to occupy the apparent P1 position in alpha-1-PI and the potential inactivation of the inhibitor by oxidation of this critical residue may be important in obtaining a biochemical link with the development of lung disease.
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Citations
Cites
The Electrophoretic α; 1 -Globulin Pattern of Serum in α; 1 -Antitrypsin Deficiency
Laurell, C.-B., & Eriksson, S. (1963) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365516309051324 · Cited by 1,393
Rapid analysis of amino acid phenylthiohydantoins by high-performance liquid chromatography
Zimmerman, C. L., Appella, E., & Pisano, J. J. (1977) · Analytical Biochemistry · doi:10.1016/0003-2697(77)90276-7 · Cited by 643
Regeneration of amino acids from thiazolinones formed in the Edman degradation
Méndez, E., & Lai, C. Y. (1975) · Analytical Biochemistry · doi:10.1016/0003-2697(75)90677-6 · Cited by 394
Selective oxidation of methionine residues in proteins
Shechter, Y., Burstein, Y., & Patchornik, A. (1975) · Biochemistry · doi:10.1021/bi00691a025 · Cited by 356
Automated amino acid sequence of small peptides utilizing Polybrene
Klapper, D. G., Wilde, C. E., & Capra, J. D. (1978) · Analytical Biochemistry · doi:10.1016/0003-2697(78)90282-8 · Cited by 321
Isolation and properties of human plasma α-1-proteinase inhibitor
Pannell, R., Johnson, D., & Travis, J. (1974) · Biochemistry · doi:10.1021/bi00723a031 · Cited by 261
Self-citation[8] Car☐ypeptidase Y in sequence determination of peptides
Hayashi, R. (1977) · Methods in Enzymology · doi:10.1016/0076-6879(77)47010-1 · Cited by 206
Arnon, R. (1970) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(70)19017-3 · Cited by 199
Trypsin Inhibitors of Human Serum
Bundy, H. F., & Mehl, J. W. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98143-3 · Cited by 125
Inactivation of human α1-proteinase inhibitor by thiol proteinases
Johnson, D. A., & Travis, J. W. (1977) · Biochemical Journal · doi:10.1042/bj1630639 · Cited by 107
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Cited by
Oxidation of methionyl residues in proteins: Tools, targets, and reversal
Vogt, W. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00158-g · Cited by 883
Johnson, D., & Travis, J. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50689-x · Cited by 466
Self-citationOwen, M. C., Brennan, S. O., Lewis, J. H., & Carrell, R. W. (1983) · New England Journal of Medicine · doi:10.1056/nejm198309223091203 · Cited by 426
Taggart, C., Cervantes-Laurean, D., Kim, G., McElvaney, N. G., Wehr, N., Moss, J., & Levine, R. L. (2000) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)61505-x · Cited by 269
Metadata
- Authors
- Johnson, D., & Travis, J.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1978-10
- Volume
- 253
- Issue
- 20
- Pages
- 7142-7144
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1553874478
- Cited by
- 259
- References
- 14
- FWCI
- 9.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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