The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Molecular characterization and expression of a gene encoding a Staphylococcus aureus collagen adhesin.
Open accessAbstract
Some strains of Staphylococcus aureus bind collagen with a high degree of specificity and affinity. This interaction can represent a mechanism of substrate adhesion and may be an important step in the pathogenesis of osteomyelitis and infectious arthritis. We now report on the cloning, sequencing, and expression of a gene name cna, encoding a S. aureus collagen adhesin. The cna gene was isolated from a lambda GT11 S. aureus genomic library and encodes an 1185 amino acid polypeptide. The deduced amino acid sequence reveals several structural characteristics similar to previously described Gram-positive bacterial cell surface proteins. Antibodies raised against the native collagen adhesin from S. aureus recognize the recombinant collagen adhesin. Collagen binding activity can be detected in a lysate obtained from Escherichia coli cells, which harbor the cloned cna gene on an expression plasmid. Collagen-binding proteins can be detected in the lysate when analyzed by a Western blot type assay in which the membrane-transferred proteins are probed with radioactively labeled collagen. Finally, the bacterial lysate containing the recombinant adhesin can effectively inhibit the binding of soluble collagen to cells of S. aureus.
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The O75X adhesin of uropathogenic Escherichia coli is a type IV collagen‐binding protein
Westerlund, B., Kuusela, P., Risteli, J., Risteli, L., Vartio, T., Rauvala, H., Virkola, R., & Korhonen, T. K. (1989) · Molecular Microbiology · doi:10.1111/j.1365-2958.1989.tb00178.x · Cited by 142
Type V collagen as the target for type‐3 fimbriae, enterobacterial adherence organelles
Tarkkanen, A. ‐., Allen, B. L., Westerlund, B., Holthöfer, H., Kuusela, P., Risteli, L., Clegg, S., & Korhonen, T. K. (1990) · Molecular Microbiology · doi:10.1111/j.1365-2958.1990.tb00714.x · Cited by 115
Cited by
Navarre, W. W., & Schneewind, O. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.1.174-229.1999 · Cited by 1,391
MSCRAMM-MEDIATED ADHERENCE OF MICROORGANISMS TO HOST TISSUES
Patti, J. M., Allen, B. L., McGavin, M. J., & Höök, M. (1994) · Annual Review of Microbiology · doi:10.1146/annurev.mi.48.100194.003101 · Cited by 1,191
Self-citationShort-sequence DNA repeats in prokaryotic genomes
van Belkum, A., Scherer, S., van Alphen, L., & Verbrugh, H. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.2.275-293.1998 · Cited by 737
Cell wall sorting signals in surface proteins of gram‐positive bacteria.
Schneewind, O., Mihaylova‐Petkov, D., & Model, P. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06169.x · Cited by 426
Sortase‐catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus
Mazmanian, S. K., Ton‐That, H., & Schneewind, O. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02411.x · Cited by 387
Metadata
- Authors
- Patti, J. M., Jonsson, H., Guss, B., Switalski, L. M., Wiberg, K., Lindberg, M., & Höök, M.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1992-03
- Volume
- 267
- Issue
- 7
- Pages
- 4766-4772
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1546476211
- Cited by
- 282
- References
- 2
- FWCI
- 10.66
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Patti, J. M., Jonsson, H., Guss, B., Switalski, L. M., Wiberg, K., Lindberg, M., & Höök, M. (1992). Molecular characterization and expression of a gene encoding a Staphylococcus aureus collagen adhesin. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)42898-0
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