The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor
Open accessAbstract
Human protein C and activated protein C are shown to bind to endothelium specifically, selectively and saturably (Kd = 30 nM, 7000 sites per cell) in a Ca(2+)-dependent fashion. Expression cloning revealed a 1.3-kilobase pair cDNA that coded for a novel type 1 transmembrane glycoprotein capable of binding protein C. This protein appears to be a member of the CD1/major histocompatibility complex superfamily. Like thrombomodulin, the receptor involved in protein C activation, the endothelial cell protein C receptor function and message are both down-regulated by exposure of endothelium to tumor necrosis factor. Identification of endothelial cell protein C receptor as a member of the CD1/major histocompatibility complex superfamily provides insights into the role of protein C in regulating the inflammatory response.
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Cites
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A new method for predicting signal sequence cleavage sites
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3′ Non-coding region sequences in eukaryotic messenger RNA
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Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis
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IDENTIFYING NONPOLAR TRANSBILAYER HELICES IN AMINO ACID SEQUENCES OF MEMBRANE PROTEINS
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Cited by
Esmon, C. T. (2003) · Chest · doi:10.1378/chest.124.3_suppl.26s · Cited by 719
Self-citationEsmon, C. T. (2003) · Journal of Thrombosis and Haemostasis · doi:10.1046/j.1538-7836.2003.00261.x · Cited by 442
Activated protein C: biased for translation
Griffin, J. H., Zlokovic, B. V., & Mosnier, L. O. (2015) · Blood · doi:10.1182/blood-2015-02-355974 · Cited by 257
Endothelial cell protein C receptor: a multiliganded and multifunctional receptor
Mohan Rao, L. V., Esmon, C. T., & Pendurthi, U. R. (2014) · Blood · doi:10.1182/blood-2014-05-578328 · Cited by 203
Self-citation(2015) · Advances in Parasitology · doi:10.1016/bs.apar.2015.02.004 · Cited by 162
Metadata
- Authors
- Fukudome, K., & Esmon, C. T.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1994-10
- Volume
- 269
- Issue
- 42
- Pages
- 26486-26491
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1570103822
- Cited by
- 517
- References
- 28
- FWCI
- 4.97
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Fukudome, K., & Esmon, C. T. (1994). Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)47220-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
