The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Studies on the Chemical and Enzymatic Modification of Glycoproteins
Open accessAbstract
Abstract A general method is described for the radioactive labeling of proteins containing terminal sialic acid in the carbohydrate moieties. Quantitative conversion of these residues to a radioactive 7-carbon analogue of sialic acid was achieved by sequential periodate oxidation and tritiated borohydride reduction. Evidence is presented to establish the identity of the radioactive derivative as 5-acetamido-3, 5-dideoxy-l-arabino-2-heptulosonic acid and to indicate it as the sole site of tritium incorporation in the carbohydrate chain. Upon injection into rats, labeled preparations of ceruloplasmin and orosomucoid exhibited a normal half-life in the plasma and proved suitable for metabolic studies. The data indicate that the 7-carbon sialic acid analogue mimics sialic acid with respect to hydrolysis by neuraminidase and in regulating survival of glycoproteins in the circulation.
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Cites
THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY
GREENWOOD, F., HUNTER, W., & GLOVER, J. (1963) · Biochemical Journal · doi:10.1042/bj0890114 · Cited by 10,152
The Thiobarbituric Acid Assay of Sialic Acids
Warren, L. (1959) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69851-5 · Cited by 6,433
Quantitive estimation of sialic acids
Svennerholm, L. (1957) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(57)90254-8 · Cited by 2,765
Dische, Z., & Shettles, L. B. (1948) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)57178-7 · Cited by 1,666
The role of sialic acid in determining the survival of glycoproteins in the circulation
Morell, A. G., Gregoriadis, G., Scheinberg, I. H., Hickman, J., & Ashwell, G. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)76994-4 · Cited by 1,072
Self-citationPhysical and Chemical Studies on Ceruloplasmin
Morell, A. G., Irvine, R. A., Sternlieb, I., Scheinberg, I. H., & Ashwell, G. (1968) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99337-3 · Cited by 476
Self-citationESTIMATION OF FORMALDEHYDE IN BIOLOGICAL MIXTURES
MacFadyen, D. A. (1945) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41599-7 · Cited by 368
Thiobarbituric Acid Spray Reagent for Deoxy Sugars and Sialic Acids
WARREN, L. (1960) · Nature · doi:10.1038/186237a0 · Cited by 320
Physical and Chemical Studies on Ceruloplasmin
Morell, A. G., Van Den Hamer, C. J. A., Scheinberg, I. H., & Ashwell, G. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99835-2 · Cited by 209
Self-citationPhysical and Chemical Studies on Ceruloplasmin
van den Hamer, C. J. A., Morell, A. G., Scheinberg, I. H., Hickman, J., & Ashwell, G. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)63808-1 · Cited by 183
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Cited by
The Isolation and Properties of a Rabbit Liver Binding Protein Specific for Asialoglycoproteins
Hudgin, R. L., Pricer, W. E., Ashwell, G., Stockert, R. J., & Morell, A. G. (1974) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)79761-9 · Cited by 615
Self-citationMembrane Receptors and Hormone Action
Cuatrecasas, P., & Hollenberg, M. D. (1976) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(08)60481-7 · Cited by 478
Gubbels, J. A., Belisle, J., Onda, M., Rancourt, C., Migneault, M., Ho, M., Bera, T. K., Connor, J., Sathyanarayana, B. K., Lee, B., et al. (2006) · Molecular Cancer · doi:10.1186/1476-4598-5-50 · Cited by 422
Cheresh, D. A., Pierschbacher, M. D., Herzig, M. A., & Mujoo, K. (1986) · The Journal of cell biology · doi:10.1083/jcb.102.3.688 · Cited by 313
Rapid isolation of plasma membranes in high yield from cultured fibroblasts
Thom, D., Powell, A. J., Lloyd, C. W., & Rees, D. A. (1977) · Biochemical Journal · doi:10.1042/bj1680187 · Cited by 302
Metadata
- Authors
- Van Lenten, L., & Ashwell, G.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1971-03
- Volume
- 246
- Issue
- 6
- Pages
- 1889-1894
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1566087596
- Cited by
- 488
- References
- 16
- FWCI
- 7.46
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Van Lenten, L., & Ashwell, G. (1971). Studies on the Chemical and Enzymatic Modification of Glycoproteins. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)62392-0
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.