The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Factors Involved in Specific Transcription by Mammalian RNA Polymerase II
Open accessAbstract
The purification and characterization of transcription factor IIF (TFIIF), a factor required for transcription by the RNA polymerase II machinery, is described. TFIIF was isolated from the previously described IIE protein fraction. TFIIF enters into the transcription cycle via a preinitiation complex, and it is required for the formation of a complex capable of initiating transcription in the presence of heparin concentrations that inhibit the action of a free factor. TFIIF and TFIIE independently interacted with purified RNA polymerase II. TFIIF and TFIIE were both required for transcription of several class II promoters, including a promoter that lacks the conserved TATA box. Interestingly TFIIF was absolutely required for the formation of a preinitiation complex; however, it also affected the elongation phase of the transcription cycle. TFIIF, together with the previously described elongation factor TFIIS, was required for efficient elongation.
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Cites
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Cited by
Molecular mechanism of nucleotide excision repair
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Self-citationFACT, a Factor that Facilitates Transcript Elongation through Nucleosomes
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Self-citationBASIC MECHANISMS OF TRANSCRIPT ELONGATION AND ITS REGULATION
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Metadata
- Authors
- Flores, O., Maldonado, E., & Reinberg, D.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1989-05
- Volume
- 264
- Issue
- 15
- Pages
- 8913-8921
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1489183905
- Cited by
- 311
- References
- 43
- FWCI
- 10.54
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Flores, O., Maldonado, E., & Reinberg, D. (1989). Factors Involved in Specific Transcription by Mammalian RNA Polymerase II. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)81880-4
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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