The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Elongation by RNA polymerase II: the short and long of it
Open accessAbstract
Appreciable advances into the process of transcript elongation by RNA polymerase II (RNAP II) have identified this stage as a dynamic and highly regulated step of the transcription cycle. Here, we discuss the many factors that regulate the elongation stage of transcription. Our discussion includes the classical elongation factors that modulate the activity of RNAP II, and the more recently identified factors that facilitate elongation on chromatin templates. Additionally, we discuss the factors that associate with RNAP II, but do not modulate its catalytic activity. Elongation is highlighted as a central process that coordinates multiple stages in mRNA biogenesis and maturation.
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Cites
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Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
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Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase
Marshall, N. F., Peng, J., Xie, Z., & Price, D. H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.43.27176 · Cited by 662 · cited 2×
“P-TEFb was originally shown to phosphorylate the CTD of RNAP II when RNA polymerase was in promoter clearance in vitro (Marshall et al. 1996).”
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A transcription reinitiation intermediate that is stabilized by activator
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Recruitment of a 19 S Proteasome Subcomplex to an Activated Promoter
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“Cross-linking studies showed that specific components of the 19S particle, but not the 20S proteolytic core, are recruited to transcriptionally active genes upon induction (Gonzalez et al. 2002).”
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Nicodeme, E., Jeffrey, K. L., Schaefer, U., Beinke, S., Dewell, S., Chung, C.-W., Chandwani, R., Marazzi, I., Wilson, P., Coste, H., et al. (2010) · Nature · doi:10.1038/nature09589 · Cited by 1,563
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals
Koike, N., Yoo, S.-H., Huang, H.-C., Kumar, V., Lee, C., Kim, T.-K., & Takahashi, J. S. (2012) · Science · doi:10.1126/science.1226339 · Cited by 1,464
Controlling the elongation phase of transcription with P-TEFb
Peterlin, B. M., & Price, D. H. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.06.014 · Cited by 1,144
Transcriptional Regulation by P53
Beckerman, R., & Prives, C. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000935 · Cited by 569
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
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Metadata
- Authors
- Sims, R. J., Belotserkovskaya, R., & Reinberg, D.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2004-10-15
- Volume
- 18
- Issue
- 20
- Pages
- 2437-2468
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2022936085
- Cited by
- 709
- References
- 9
- Type
- posted content
- Language
- en
- Open access
- diamond
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