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Cited by 379

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Exchange of Phospholipids between Liver Mitochondria and Microsomes in Vitro

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Wirtz, K W A, Zilversmit, D B·1968·Journal of Biological Chemistry
DOI 10.1016/s0021-9258(19)34182-1
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Abstract

Abstract A 10% rat liver homogenate in 0.25 m sucrose-10-3 m ethylenediaminetetraacetate was fractionated into mitochondria, microsomes, and a supernatant fraction. Liver mitochondria derived from rats injected with leucine-3H and with phosphate-32P or with glycerol-14C were incubated with nonlabeled microsomes in the presence of supernatant or of sucrose-EDTA. Labeled microsomes were similarly exposed to nonlabeled mitochondria. 32P or glycerol-14C was used to measure exchange of phospholipid; 3H was used to correct for contamination of mitochondria by microsomes. After 90 min at 37° 30 to 40% of the phospholipid in the particulate fractions had exchanged while at 0° 10% exchange took place. Phosphatidyl choline appeared to exchange to a greater extent than phosphatidyl ethanolamine, whereas cardiolipin of the mitochondrial fraction did not exchange. The extent of exchange was reduced 50 to 60% when sucrose-EDTA was substituted for the supernatant fraction as incubation medium.

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Metadata

Authors
Wirtz, K. W. A., & Zilversmit, D. B.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1968-07
Volume
243
Issue
13
Pages
3596-3602
ISSN
0021-9258 (ISSN-L)
DOI
10.1016/s0021-9258(19)34182-1
OpenAlex
W1549802820
Cited by
379
References
13
FWCI
13.27
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Exchange of Phospholipids between Liver Mitochondria and Microsomes in Vitro. https://app.cochat.ai/papers/10.1016/s0021-9258(19)34182-1
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Wirtz, K. W. A., & Zilversmit, D. B. (1968). Exchange of Phospholipids between Liver Mitochondria and Microsomes in Vitro. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)34182-1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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