Cited by 199Ion Transport and Channel RegulationATP Synthase and ATPases ResearchElectromagnetic Fields and Biological Effects

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Activation of Na+ and K+ pumping modes of (Na, K)-ATPase by an oscillating electric field

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Liu, D S, Astumian, R D, Tsong, T Y·1990·Journal of Biological Chemistry

DOI 10.1016/s0021-9258(19)39108-2

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Abstract

Serpersu and Tsong (Sepersu, E. H., and Tsong, T. Y. (1983) J. Membr. Biol. 74, 191-201; (1984) J. Biol. Chem. 259, 7155-7162) reported activation of a K+ pumping mode of (Na,K)-ATPase by an oscillating electric field (20 V/cm, 1.0 kHz). Their attempts to activate Na+ pumping at the same frequency were unsuccessful. We report here activation of a Na+ pumping mode with an oscillating electric field of the same strength as used previously (20 V/cm) but at a much higher frequency (1.0 MHz). At 3.5 degrees C and the optimal amplitude and frequency, the field-induced, ouabain-sensitive (0.2 mM ouabain incubated for 30 min) Rb+ influx ranged between 10 and 20 amol/red blood cell/h, and the corresponding Na+ efflux ranged between 15 and 30 amol/red blood cell/h, varying with the source of the erythrocytes. No Rb+ efflux nor Na+ influx was stimulated by the applied field in the frequency range 1 Hz to 10 MHz. These results indicate that only those transport modes that require ATP splitting under the physiological condition were affected by the applied electric fields, although the field-stimulated Rb+ influx and Na+ efflux did not depend on the cellular ATP concentration in the range 5 to 800 microM. Computer simulation of a four-state enzyme electroconformationally coupled to an alternating electric field (Tsong, T. Y., and Astumian, R. D. (1986) Bioelectrochem. Bioenerg. 15, 457-476; Tsong, T. Y. (1990) Annu. Rev. Biophys. Biophys. Chem. 19, 83-106) reproduced the main features of the above results.

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The Enzymes of Biological Membranes
Martonosi, A. N. (1985) · Springer eBooks · doi:10.1007/978-1-4613-2355-6 · Cited by 1,356
[65] Assays of intermediates of the citric acid cycle and related compounds by fluorometric enzyme methods
WILLIAMSON, J. R., & Corkey, B. E. (1969) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(69)13072-4 · Cited by 867
Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.
Cantley, L. C., Josephson, L., Warner, R. K., Yanagisawa, M., Lechène, C., & Guidotti, G. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40978-1 · Cited by 832
Mechanism of the Na+, K+ pump protein structure and conformations of the pure
Jørgensen, P. L. (1982) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(82)90013-2 · Cited by 505
Transport adenosine triphosphatases: properties and functions.
Stekhoven, F. S., & BONTING, S. L. (1981) · Physiological Reviews · doi:10.1152/physrev.1981.61.1.1 · Cited by 468
The linkage of sodium, potassium, and ammonium active transport across the human erythrocyte membrane
Post, R. L., & Jolly, P. C. (1957) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(57)90426-2 · Cited by 422
Vanadate inhibits the red cell (Na+, K+) ATPase from the cytoplasmic side
Cantley, L. C., Resh, M. D., & Guidotti, G. (1978) · Nature · doi:10.1038/272552a0 · Cited by 378
Structure and Mechanism of the (Na,K)-ATPase
Cantley, L. C. (1981) · Current topics in bioenergetics · doi:10.1016/b978-0-12-152511-8.50012-8 · Cited by 320
Electric field induced transient pores in phospholipid bilayer vesicles
Teissié, J., & Tsong, T. Y. (1981) · Biochemistry · doi:10.1021/bi00509a022 · Cited by 319
The stoicheiometry of the sodium pump
Garrahan, P. J., & Glynn, I. M. (1967) · The Journal of Physiology · doi:10.1113/jphysiol.1967.sp008297 · Cited by 301

Show all 43 references

Research works printed but not linked: 7

Glynn, 1985, 3, 35
Tosteson, 1981, Fed. Proc., 40, 1429
Escobales, 1986, J. Membr. Biol., 96, 1
Schatzmann, 1953, Helv. Physiol. Pharmacol. Acta, 11, 346
Hoffman, 1979, Fed. Proc., 28, 2440
Neumann, 1973, J. Membr. Biol., 14, 194
Vinckler, 1982, Proc. Natl. Acad. Sci. U. S. A., 79, 3181

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Authors: Liu, D. S., Astumian, R. D., & Tsong, T. Y.
Affiliations: University of Minnesota (US)
ORCID: Astumian, R D
Venue: Journal of Biological Chemistry
Publisher: Elsevier BV
Published: 1990-05
Volume: 265
Issue: 13
Pages: 7260-7267
ISSN: 0021-9258 (ISSN-L)
DOI: 10.1016/s0021-9258(19)39108-2
OpenAlex: W1608844245
Cited by: 199
References: 43
Citations by year: 2026: 2 · 2024: 4 · 2023: 1 · 2022: 3 · 2021: 4 · 2020: 6 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 10 · 2015: 2 · 2012: 4
FWCI: 5.84
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by/4.0/ (vor, 11130 d)
Locations: Journal of Biological Chemistry (publishedVersion, cc-by)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › ATP Synthase and ATPases Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Electromagnetic Fields and Biological Effects
Keywords: Na+/K+-ATPase, oscillating electric field, Na+ efflux, erythrocytes, ouabain sensitivity, ATP hydrolysis, erythrocyte membrane
MeSH terms: Sodium-Potassium-Exchanging ATPase, Adenosine Triphosphate, Biological Transport, Active, Electric Stimulation, Erythrocytes, Humans, Kinetics, Mathematics, Models, Theoretical, Ouabain, Potassium, Rubidium, Sodium, Spectrometry, Fluorescence

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Activation of Na+ and K+ pumping modes of (Na, K)-ATPase by an oscillating electric field

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