The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Millimolar concentrations of ascorbic acid in purified human mononuclear leukocytes. Depletion and reaccumulation.
Open accessAbstract
Ascorbic acid (vitamin C) was found in isolated human mononuclear leukocytes and their purified components in millimolar concentration. Intracellular ascorbic acid was depleted greater than 96% during cell culture and was rapidly reaccumulated after addition of physiologic concentrations of ascorbic acid to the extracellular medium. Purified cells maintained concentration gradients of ascorbic acid as large as 100-fold across the plasma membrane. The ability to vary intracellular ascorbic acid concentrations over such a wide range makes it possible for the first time in these cells to study ascorbic acid function in direct relationship to intracellular concentration.
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Citations
Cites
Ascorbic acid in lymphocytes: Cell preparation and liquid-chromatographic assay
Lee, W., Hamernyik, P., Hutchinson, M., Raisys, V. A., & Labbé, R. F. (1982) · Clinical Chemistry · doi:10.1093/clinchem/28.10.2165 · Cited by 97
Cited by
Carr, A., & Maggini, S. (2017) · Nutrients · doi:10.3390/nu9111211 · Cited by 2,035
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Levine, M., Conry-Cantilena, C., Wang, Y., Welch, R. W., Washko, P. W., Dhariwal, K. R., Park, J. B., Lazarev, A., Graumlich, J. F., King, J., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.8.3704 · Cited by 1,325
Self-citationChromium in Drinking Water: Sources, Metabolism, and Cancer Risks
Zhitkovich, A. (2011) · Chemical Research in Toxicology · doi:10.1021/tx200251t · Cited by 1,132
Chen, Q., Espey, M. G., Krishna, M. C., Mitchell, J. B., Corpe, C. P., Buettner, G. R., Shacter, E., & Levine, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506390102 · Cited by 1,075
Self-citationCommentary: Vitamin C: Antioxidant or Pro-Oxidant In Vivo?
Halliwell, B. (1996) · Free Radical Research · doi:10.3109/10715769609149066 · Cited by 531
Metadata
- Authors
- Bergsten, P., Amitai, G., Kehrl, J., Dhariwal, K. R., Klein, H. G., & Levine, M.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1990-02
- Volume
- 265
- Issue
- 5
- Pages
- 2584-2587
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1491755566
- Cited by
- 199
- References
- 1
- FWCI
- 8.17
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Bergsten, P., Amitai, G., Kehrl, J., Dhariwal, K. R., Klein, H. G., & Levine, M. (1990). Millimolar concentrations of ascorbic acid in purified human mononuclear leukocytes. Depletion and reaccumulation. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)39841-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
