The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Generation of Superoxide Free Radical during the Autoxidation of Thiols
Open accessAbstract
The autoxidation of dithiothreitol, 2-mercaptoethanol, reduced glutathione, and ethyl mercaptan has been seen to involve the univalent reduction of oxygen. The superoxide radicals, so generated, were detected by their ability to reduce p-nitroblue tetrazolium to a formazan and by the inhibition of this reaction by superoxide dismutase. The rate of autoxidation of these thiols and the sensitivity of the reduction of nitroblue tetrazolium to inhibition by superoxide dismutase were both augmented, as the pH was raised from 7.8 to 10.2. These results, lead to the proposal that thiols reduce nitroblue tetrazolium by at least two different pathways, one of which involves O2- and is therefore inhibitable by superoxide dismutase.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels
Beauchamp, C., & Fridovich, I. (1971) · Analytical Biochemistry · doi:10.1016/0003-2697(71)90370-8 · Cited by 12,892
Cited by
[1] Role of free radicals and catalytic metal ions in human disease: An overview
Halliwell, B., & Gutteridge, J. M. C. (1990) · Methods in Enzymology · doi:10.1016/0076-6879(90)86093-b · Cited by 4,994
Superoxide radical and superoxide dismutases
Fridovich, I. (1995) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.64.070195.000525 · Cited by 3,455
Fridovich (1978) · doi:10.1126/science.210504 · Cited by 3,329
Homocysteine and Atherothrombosis
Welch, G. N., & Loscalzo, J. (1998) · New England Journal of Medicine · doi:10.1056/nejm199804093381507 · Cited by 1,997
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide
Winterbourn, C. C., & Metodiewa, D. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00051-9 · Cited by 799
Metadata
- Authors
- Misra, H. P.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1974-04
- Volume
- 249
- Issue
- 7
- Pages
- 2151-2155
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1554237512
- Cited by
- 556
- References
- 1
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Generation of Superoxide Free Radical during the Autoxidation of Thiols. https://app.cochat.ai/papers/10.1016/s0021-9258(19)42810-x
- The paper
- Misra, H. P. (1974). Generation of Superoxide Free Radical during the Autoxidation of Thiols. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)42810-x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
