The DOI matches its Crossref record; 56 of the 58 references it cites were found in a registry or an index.
Regulation of HMG-CoA reductase activity in plants.
Open accessAbstract
This brief review summarizes the current literature on the regulation of HMG-CoA reductase (HMGR) in plants. The mevalonate pathway, which starts with the synthesis of mevalonate by HMGR, has more branch pathways in plants than in most other organisms, leading to a tremendous variety of isoprenoid products. Evidence suggests that HMGR is an important control point for the synthesis of many of these plant isoprenoids, including some that are vital for primary metabolism and pest resistance. Plant HMGR activity responds in vivo to a variety of developmental and environmental signals, such as cell division, light, and infection. Plants regulate HMGR activity at the level of mRNA by differential induction of HMGR gene family members, and posttranslationally by enzyme modification. Calcium, calmodulin, and proteolytic degradation may also have a role in regulation of plant HMGR.
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“Stermer et al. showed that the HMGR activity is much reduced in mature tissues, correlating well with the results presented here [27].”
From Relative expression of genes of terpene metabolism in different tissues of Artemisia annuaL (2011) · cites this paper as [27]
Citations
Cites
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- Knight, J. S. 1982. Studies on the protein kinase which catalyzes the inactivation of microsomal HMG-CoA reduc?tase. Senior thesis, University of Otago, Dunedin, New Zealand.
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Items 201–216 of 216
Denbow, C. J. (1997) · VTechWorks (Virginia Tech)
Schmid, K. M. (2004) · Wiley eBooks · doi:10.1002/0470869143.kc024
Analysis of OeMVK Gene Expression in Different Olive Tissues Using Real Time PCR
Sönmez, G. D. (2019) · Adıyaman üniversitesi fen bilimleri dergisi · doi:10.37094/adyujsci.530868
Cloning and characterization of CbHMGR and CbSQS genes in Conyza blinii
Sun, R., Gao, J., Liu, S., & Chen, H. (2021) · doi:10.2478/s11756-020-00671-z
Kharbikar, L. L., Shanware, A., Nandanwar, S. K., SAHARAN, M. S., Marathe, A., Mishra, N. S., & Edwards, S. G. (2021) · Research Square · doi:10.21203/rs.3.rs-795898/v1
Reil, G., & Berger, R. G. (2010) · Woodhead Publishing Limited eBooks · doi:10.1533/9781845698232.2.95
Sarkar, J., & Banerjee, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-21818-7.00026-5
Biosynthèse et rôle biologique des diterpènes dans les graines de caféiers
Antoine, G. (2022) · theses.fr (ABES) · doi:10.70675/5e45bb7az93d3z4c80zbc60zed1b729bd936
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Faulks (2000) · doi:10.1002/(sici)1097-0010(20000515)80:7
Metadata
- Authors
- Stermer, B. A., Bianchini, G. M., & Korth, K. L.
- Affiliations
- Noble Research Institute (US)
- ORCID
- Korth, K L
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1994-07
- Volume
- 35
- Issue
- 7
- Pages
- 1133-1140
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2340545711
- Cited by
- 216
- References
- 58
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 7 · 2023: 5 · 2022: 12 · 2021: 6 · 2020: 5 · 2019: 9 · 2018: 7 · 2017: 10 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 7 · 2012: 6
- FWCI
- 3.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Lipid Research (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Keywords
- HMG-CoA reductase, mevalonate pathway, isoprenoid biosynthesis, enzyme regulation, gene expression regulation, post-translational modification, calcium signaling, calmodulin, proteolysis, plant development, light signaling, plant-pathogen interaction, pest resistance, primary metabolism
- MeSH terms
- Calcium, Cell Compartmentation, Hydroxymethylglutaryl CoA Reductases, Peptide Hydrolases, Phosphorylation, Plants, Transcription, Genetic, Signal Transduction
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