The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux.
Open accessAbstract
Published data related to both cell membrane biology and apolipoprotein structure are reviewed and used to formulate a new model describing the mechanisms of cholesterol efflux from cell plasma membrane to high density lipoprotein (HDL) particles. The central premise of this model is the existence of heterogenous domains of cholesterol within plasma membranes. We propose that cholesterol efflux from cell membranes is influenced by three factors: 1) the distribution of cholesterol between cholesterol-rich and cholesterol-poor membrane domains, 2) the diffusion of cholesterol molecules through the extracellular unstirred water layer, and 3) the transient interaction of segments of the amphipathic helix of the HDL apolipoprotein with cholesterol-poor membrane domains resulting in enhanced cholesterol efflux.
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Citations
Cites
The plasma lecithin:cholesterol acyltransferase reaction
Glomset, J. A. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43114-1 · Cited by 2,405
High density lipoprotein metabolism.
Eisenberg, S. (1984) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37713-0 · Cited by 1,210
Segrest, J., Jones, M., De Loof, H., Brouillette, C., Venkatachalapathi, Y., & Anantharamaiah, G. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41536-6 · Cited by 866
On the structure of charged interfaces
Bockris, J. O., Devanathan, M. A. V., & Müller, K. J. (1963) · Proceedings of the Royal Society of London A Mathematical and Physical Sciences · doi:10.1098/rspa.1963.0114 · Cited by 716
Early incorporation of cell-derived cholesterol into pre-.beta.-migrating high-density lipoprotein
Castro, G. R., & Fielding, C. J. (1988) · Biochemistry · doi:10.1021/bi00401a005 · Cited by 642
Amphipathic helix motif: Classes and properties
Segrest, J. P., De Loof, H., Dohlman, J. G., Brouillette, C. G., & Anantharamaiah, G. M. (1990) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.340080202 · Cited by 642
Mechanisms and consequences of cellular cholesterol exchange and transfer
Phillips, M. C., Johnson, W. J., & Rothblat, G. H. (1987) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(87)90013-x · Cited by 541
Self-citationCholesterol transport between cells and high-density lipoproteins
Johnson, W. J., Mahlberg, F. H., Rothblat, G. H., & Phillips, M. C. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90132-2 · Cited by 443
Self-citationAn Introduction to Biological Membranes
(2016) · Elsevier eBooks · doi:10.1016/c2015-0-06226-8 · Cited by 364
Linden, C. D., Wright, K. L., McConnell, H. M., & Fox, C. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.8.2271 · Cited by 301
Cited by
Molecular physiology of reverse cholesterol transport.
Fielding, C. J., & Fielding, P. E. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39898-9 · Cited by 1,448
Cellular Cholesterol Efflux Mediated by Cyclodextrins
Kilsdonk, E. P. C., Yancey, P. G., Stoudt, G. W., Bangerter, F. W., Johnson, W. J., Phillips, M. C., & Rothblat, G. H. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.29.17250 · Cited by 890
Self-citationAcute cholesterol depletion inhibits clathrin-coated pit budding
Subtil, A., Gaidarov, I., Kobylarz, K., Lampson, M. A., Keen, J. H., & McGraw, T. E. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.12.6775 · Cited by 578
Cell cholesterol efflux: integration of old and new observations provides new insights
Rothblat, G. H., de la Llera-Moya, M., Atger, V., Kellner-Weibel, G., Williams, D. L., & Phillips, M. C. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32113-1 · Cited by 503
Self-citationCellular Cholesterol Efflux Mediated by Cyclodextrins
Yancey, P. G., Rodrigueza, W. V., Kilsdonk, E. P. C., Stoudt, G. W., Johnson, W. J., Phillips, M. C., & Rothblat, G. H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.27.16026 · Cited by 458
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Metadata
- Authors
- Rothblat, G., Mahlberg, F., Johnson, W., & Phillips, M.
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1992-08
- Volume
- 33
- Issue
- 8
- Pages
- 1091-1097
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2341638556
- Cited by
- 266
- References
- 37
- FWCI
- 23.97
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Rothblat, G., Mahlberg, F., Johnson, W., & Phillips, M. (1992). Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux. Journal of Lipid Research. https://doi.org/10.1016/s0022-2275(20)40761-8
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
