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IDENTIFICATION AND ASSAY OF SEROTONIN IN BRAIN
Abstract
1. A fluorometric method for the determination of serotonin (5-hydroxytryp-tamine) in brain is described. The procedure involves the use of a spectrophoto-fluorometer which can activate and measure emitted fluorescence continuously from 250 to 650 mµ. Serotonin is activated maximally at 295 mµ and emits fluorescent light which shows a maximum at 550 mµ. 2. With this method serotonin has been shown to be a normal constituent of brain. 3. The fluorescent procedure may be applied to the measurement of serotonin in other tissues.
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Citations
Cited by
Steinbusch, H. W. M. (1981) · Neuroscience · doi:10.1016/0306-4522(81)90146-9 · Cited by 2,415
In vitro studies on central and peripheral monoamine neurons at the ultrastructural level
H�kfelt, T. (1968) · Zeitschrift f�r Zellforschung und Mikroskopische Anatomie · doi:10.1007/bf00336984 · Cited by 499
Blood serotonin levels in autism spectrum disorder: A systematic review and meta-analysis
Gabriele, S., Sacco, R., & Persico, A. M. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.02.004 · Cited by 346
Hyperserotonemia and amine metabolites in autistic and retarded children
Hanley, H. G. (1977) · Archives of General Psychiatry · doi:10.1001/archpsyc.1977.01770170031002 · Cited by 230
The Neuronatomy of the Serotonergic System
Hornung, J.-P. (2010) · Handbook of Behavioral Neuroscience · doi:10.1016/s1569-7339(10)70071-0 · Cited by 45
Metadata
- Authors
- Bogdanski, D. F., Pletscher, A., Brodie, B. B., & Udenfriend, S.
- Venue
- The Journal of Pharmacology and Experimental Therapeutics
- Publisher
- Elsevier BV
- Published
- 1956-05
- Volume
- 117
- Issue
- 1
- Pages
- 82-88
- ISSN
- 0022-3565 (ISSN-L)
- OpenAlex
- W2163612179
- Cited by
- 861
- References
- 0
- FWCI
- 14.84
- Type
- journal article
- Language
- en
- Open access
- closed
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: IDENTIFICATION AND ASSAY OF SEROTONIN IN BRAIN. https://app.cochat.ai/papers/10.1016/s0022-3565(25)11657-1
- The paper
- Bogdanski, D. F., Pletscher, A., Brodie, B. B., & Udenfriend, S. (1956). IDENTIFICATION AND ASSAY OF SEROTONIN IN BRAIN. The Journal of Pharmacology and Experimental Therapeutics. https://doi.org/10.1016/s0022-3565(25)11657-1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
