Blood serotonin levels in autism spectrum disorder: A systematic review and meta-analysis

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works

Diagnostic and Statistical Manual of Mental Disorders, 5th ed.

Carter, M. J. (2014) · Therapeutic Recreation Journal · Cited by 15,154 · see citing works

Meta-analysis: Principles and procedures

Egger, M., Smith, G. D., & Phillips, A. N. (1997) · BMJ · doi:10.1136/bmj.315.7121.1533 · Cited by 2,415 · see citing works

IDENTIFICATION AND ASSAY OF SEROTONIN IN BRAIN

Bogdanski, D. F., Pletscher, A., Brodie, B. B., & Udenfriend, S. (1956) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)11657-1 · Cited by 861 · see citing works

A transient placental source of serotonin for the fetal forebrain

Bonnin, A., Goeden, N., Chen, K., Wilson, M. L., King, J., Shih, J. C., Blakely, R. D., Deneris, E. S., & Levitt, P. (2011) · Nature · doi:10.1038/nature09972 · Cited by 608 · see citing works

Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children

Schain, R. J., & Freedman, D. X. (1961) · The Journal of Pediatrics · doi:10.1016/s0022-3476(61)80261-8 · Cited by 579 · see citing works

Primary Structure of the Human Platelet Serotonin Uptake Site: Identity with the Brain Serotonin Transporter

Lesch, K., Wolozin, B. L., Murphy, D. L., & Riederer, P. F. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb03522.x · Cited by 537 · see citing works

Review article: serotonin receptors and transporters — roles in normal and abnormal gastrointestinal motility

Gershon, M. D. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.02180.x · Cited by 521 · see citing works

Meta-analysis: Its strengths and limitations

WALKER, E., HERNANDEZ, A. V., & KATTAN, M. W. (2008) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.75.6.431 · Cited by 519 · see citing works

Targeting the murine serotonin transporter: insights into human neurobiology

Murphy, D. L., & Lesch, K.-P. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2284 · Cited by 478 · see citing works

The developmental neurobiology of autism spectrum disorder

DiCicco-Bloom, E., Lord, C., Zwaigenbaum, L., Courchesne, E., Dager, S. R., Schmitz, C., Schultz, R. T., Crawley, J., & Young, L. J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1712-06.2006 · Cited by 434 · see citing works

The serotonin system in autism

Cook, E. H., & LEVENTHAL, B. L. (1996) · Current Opinion in Pediatrics · doi:10.1097/00008480-199608000-00008 · Cited by 394 · see citing works

Brain Serotonin and Dopamine Transporter Bindings in Adults With High-Functioning Autism

Nakamura, K., Sekine, Y., Ouchi, Y., Tsujii, M., Yoshikawa, E., Futatsubashi, M., Tsuchiya, K. J., Sugihara, G., Iwata, Y., Suzuki, K., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.137 · Cited by 352 · see citing works

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

Veenstra-VanderWeele, J., Muller, C. L., Iwamoto, H., Sauer, J. E., Owens, W. A., Shah, C. R., Cohen, J., Mannangatti, P., Jessen, T., Thompson, B. J., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1112345109 · Cited by 333 · see citing works

Whole blood serotonin in autistic and normal subjects

Anderson, G. M., Freedman, D. X., Cohen, D. J., Volkmar, F. R., Hoder, E. L., McPhedran, P., Minderaa, R. B., Hansen, C. R., & Young, J. G. (1987) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1987.tb00677.x · Cited by 313 · see citing works

The conundrums of understanding genetic risks for autism spectrum disorders

State, M. W., & Levitt, P. (2011) · Nature Neuroscience · doi:10.1038/nn.2924 · Cited by 306 · see citing works

Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome

Wan, M. W., Green, J., Elsabbagh, M., Johnson, M., Charman, T., Plummer, F., & the BASIS Team (2013) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12032 · Cited by 266 · see citing works

Increased Blood Serotonin and Platelets in Early Infantile Autism

RITVO, E. R. (1970) · Archives of General Psychiatry · doi:10.1001/archpsyc.1970.01750060086009 · Cited by 249 · see citing works

In search of biomarkers for autism: scientific, social and ethical challenges

Walsh, P., Elsabbagh, M., Bolton, P., & Singh, I. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3113 · Cited by 249 · see citing works

Hyperserotonemia and amine metabolites in autistic and retarded children

Hanley, H. G. (1977) · Archives of General Psychiatry · doi:10.1001/archpsyc.1977.01770170031002 · Cited by 230 · see citing works

Platelet serotonin levels in Pervasive Developmental Disorders and mental retardation: Diagnostic group differences, within-group distribution, and behavioral correlates

Mulder, E. J., Anderson, G. M., Kema, I. P., de Bildt, A., van Lang, N. D., den Boer, J. A., & Minderaa, R. B. (2004) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200404000-00016 · Cited by 199 · see citing works

Whole blood serotonin and plasma beta-endorphin in autistic probands and their first-degree relatives

Leboyer, M., Philippe, A., Bouvard, M., Guilloud-Bataille, M., Bondoux, D., Tabuteau, F., Feingold, J., Mouren-Simeoni, M.-C., & Launay, J.-M. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00532-5 · Cited by 194 · see citing works

Biomarkers in autism spectrum disorder: the old and the new

Ruggeri, B., Sarkans, U., Schumann, G., & Persico, A. M. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3290-7 · Cited by 191 · see citing works

Cortical Serotonin 5-HT 2A Receptor Binding and Social Communication in Adults With Asperger’s Syndrome: An in Vivo SPECT Study

Murphy, D., Daly, E., Schmitz, N., Toal, F., Murphy, K., Curran, S. R., Erlandsson, K., Eersels, J. L. H., Kerwin, R. W., Ell, P. J., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.5.934 · Cited by 181 · see citing works

Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase

Prasad, H. C., Zhu, C.-B., McCauley, J. L., Samuvel, D. J., Ramamoorthy, S., Shelton, R. C., Hewlett, W. A., Sutcliffe, J. S., & Blakely, R. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501432102 · Cited by 180 · see citing works

Evidence for Sex-Specific Risk Alleles in Autism Spectrum Disorder

Stone, J. L., Merriman, B., Cantor, R. M., Yonan, A. L., Gilliam, T. C., Geschwind, D. H., & Nelson, S. F. (2004) · The American Journal of Human Genetics · doi:10.1086/426034 · Cited by 176 · see citing works

Replication of Autism Linkage: Fine-Mapping Peak at 17q21

Cantor, R. M., Kono, N., Duvall, J. A., Alvarez-Retuerto, A., Stone, J. L., Alarcón, M., Nelson, S. F., & Geschwind, D. H. (2005) · The American Journal of Human Genetics · doi:10.1086/430278 · Cited by 157 · see citing works

Primary Structure of the Human Platelet Serotonin 5‐HT2A Receptor: Identity with Frontal Cortex Serotonin 5‐HT2A Receptor

Cook, E. H., Fletcher, K. E., Wainwright, M. S., Marks, N., Yan, S., & LEVENTHAL, B. L. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63020465.x · Cited by 150 · see citing works

Platelet serotonin, a possible marker for familial autism

Piven, J., Tsai, G. E., Nehme, E., COYLE, J. T., Chase, G. A., & Folstein, S. E. (1991) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02206997 · Cited by 147 · see citing works

A rapid accurate procedure for the determination of serotonin in whole human blood

Yuwiler, A., Plotkin, S., Geller, E., & RITVO, E. R. (1970) · Biochemical Medicine · doi:10.1016/0006-2944(70)90010-4 · Cited by 143 · see citing works

Effects of Diagnosis, Race, and Puberty on Platelet Serotonin Levels in Autism and Mental Retardation

MCBRIDE, P. A., ANDERSON, G. M., HERTZIG, M. E., SNOW, M. E., THOMPSON, S. M., KHAIT, V. D., SHAPIRO, T., & COHEN, D. J. (1998) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199807000-00017 · Cited by 141 · see citing works

Sex-specific genetic architecture of whole blood serotonin levels

Weiss, L. A., Abney, M., Cook, E. H., & Ober, C. (2005) · The American Journal of Human Genetics · doi:10.1086/426697 · Cited by 137 · see citing works

Variants of the serotonin transporter gene (SLC6A4) significantly contribute to hyperserotonemia in autism

Coutinho, A. M., Oliveira, G. G., Morgadinho, T., Fesel, C., Macedo, T. R. A., Bento, C., Marques, C., Ataíde, A., Miguel, T., Borges, L., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001409 · Cited by 136 · see citing works

Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

Veenstra-VanderWeele, J., & Blakely, R. D. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.185 · Cited by 128 · see citing works

Elevated blood serotonin in autistic probands and their first-degree relatives

Abramson, R. K., Wright, H. H., Carpenter, R., Brennan, W., Lumpuy, O., Cole, E., & Young, S. R. (1989) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212938 · Cited by 123 · see citing works

Hyperserotonemia in Adults with Autistic Disorder

Hranilović, D., Bujas-Petković, Z., Vragović, R., Vuk, T., Hock, K., & Jernej, B. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0324-6 · Cited by 119 · see citing works

The Measurement of Platelet-Poor Plasma Serotonin: A Systematic Review of Prior Reports and Recommendations for Improved Analysis

Brand, T., & Anderson, G. M. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2011.163824 · Cited by 119 · see citing works

Autistic children and their first-degree relatives: relationships between serotonin and norepinephrine levels and intelligence

Cook, E. H., LEVENTHAL, B. L., Heller, W., Metz, J. T., Wainwright, M. S., & Freedman, D. X. (1990) · Journal of Neuropsychiatry · doi:10.1176/jnp.2.3.268 · Cited by 104 · see citing works

Principal pathogenetic components and biological endophenotypes in autism spectrum disorders

Sacco, R., Curatolo, P., Manzi, B., Militerni, R., Bravaccio, C., Frolli, A., Lenti, C., Saccani, M., Elia, M., Reichelt, K.-L., et al. (2010) · Autism Research · doi:10.1002/aur.151 · Cited by 102 · see citing works

Relationships of whole blood serotonin and plasma norepinephrine within families

Leventhal, B. L., Cook, E. H., Morford, M., Ravitz, A., & Freedman, D. X. (1990) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02216055 · Cited by 102 · see citing works

Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility

Weiss, L. A., Kosova, G., Delahanty, R., Jiang, L., Cook, E. H., Ober, C., & Sutcliffe, J. S. (2006) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201644 · Cited by 92 · see citing works

Free serotonin in plasma: Autistic children and their first-degree relatives

Cook, E. H., LEVENTHAL, B. L., & Freedman, D. X. (1988) · Biological Psychiatry · doi:10.1016/0006-3223(88)90192-8 · Cited by 83 · see citing works

Peripheral Markers of Serotonergic and Noradrenergic Function in Post-Pubertal, Caucasian Males with Autistic Disorder

Croonenberghs, J. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00131-1 · Cited by 77 · see citing works

Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin

Weiss, L. A., Veenstra-VanderWeele, J. M., Newman, D. L., Kim, S., Dytch, H. E., McPeek, M. S., Cheng, S., Ober, C., Cook, E. H., & Abney, M. (2004) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201239 · Cited by 68 · see citing works

Blood Serotonin and Free Tryptophan Concentration in Autistic Children

Hoshino, Y., Yamamoto, T., Kaneko, M., Tachibana, R., Watanabe, M., Ono, Y., & Kumashiro, H. (2008) · Neuropsychobiology · doi:10.1159/000118045 · Cited by 65 · see citing works

Multifactor Dimensionality Reduction–Phenomics: A Novel Method to Capture Genetic Heterogeneity with Use of Phenotypic Variables

Mei, H., Cuccaro, M. L., & Martin, E. R. (2007) · The American Journal of Human Genetics · doi:10.1086/522307 · Cited by 63 · see citing works

Differentiating Autism Spectrum Disorder From Other Developmental Delays In The First Two Years Of Life

Mitchell, S., Cardy, J. O., & Zwaigenbaum, L. (2011) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.1107 · Cited by 62 · see citing works

Serotonin Relationships of Autistic Probands and Their First-Degree Relatives

Samuel Kuperman, C., Beeghly, J. H. L., Burns, T. L., & Tsai, L. Y. (1985) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)60446-5 · Cited by 61 · see citing works

Plasma androgens in autism

Tordjman, S., Anderson, G. M., McBride, P., Hertzig, M. E., Snow, M. E., Hall, L. M., Ferrari, P., & Cohen, D. J. (1995) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02179290 · Cited by 60 · see citing works

Family-based association study of ITGB3 in autism spectrum disorder and its endophenotypes

Napolioni, V., Lombardi, F., Sacco, R., Curatolo, P., Manzi, B., Alessandrelli, R., Militerni, R., Bravaccio, C., Lenti, C., Saccani, M., et al. (2010) · European Journal of Human Genetics · doi:10.1038/ejhg.2010.180 · Cited by 59 · see citing works

Serotonin transporter gene promoter variants do not explain the hyperserotoninemia in autistic children

Persico, A. M., Pascucci, T., Puglisi‐Allegra, S., Militerni, R., Bravaccio, C., Schneider, C., Melmed, R. D., Trillo, S., Montecchi, F., Palermo, M. T., et al. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001069 · Cited by 56 · see citing works

Hyperserotoninemia and antiserotonin antibodies in autism and other disorders

Yuwiler, A., Shih, J. C., Chen, C.-H., RITVO, E. R., Hanna, G. L., Ellison, G. W., & King, B. H. (1992) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01046401 · Cited by 53 · see citing works

Urinary 5-hydroxyindoleacetic acid and whole blood serotonin and tryptophan in autistic and normal subjects

Minderaa, R. B., Anderson, G. M., Volkmar, F. R., Akkerhuis, G. W., & Cohen, D. J. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90002-3 · Cited by 52 · see citing works

Increased Density of the Platelet Serotonin Transporter in Autism

Marazziti, D., Muratori, F., Cesari, A., Másala, I., Baroni, S., Giannaccini, G., Dell’Osso, L., Cosenza, A., Pfanner, P., & Cassano, G. (2000) · Pharmacopsychiatry · doi:10.1055/s-2000-7588 · Cited by 47 · see citing works

Examination of circadian rhythmicity of blood serotonin and platelets in autistic and non-autistic children

Yuwiler, A., RITVO, E. R., Bald, D., Kipper, D. A., & Koper, A. (1971) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01540533 · Cited by 47 · see citing works

ITGB3 shows genetic and expression interaction with SLC6A4

Weiss, L. A., Ober, C., & Cook, E. H. (2006) · Human Genetics · doi:10.1007/s00439-006-0196-z · Cited by 44 · see citing works

Plasma Serotonin in Autism

Connors, S. L., Matteson, K. J., Sega, G. A., Lozzio, C. B., Carroll, R. C., & Zimmerman, A. W. (2006) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2006.02.010 · Cited by 44 · see citing works

Roles for Serotonin in Neurodevelopment: More than just Neural Transmission

Pino, G. D., Moessner, R., Lesch, K., Lauder, J. M., & Persico, A. M. (2004) · Current Neuropharmacology · doi:10.2174/1570159043359495 · Cited by 44 · see citing works

Neuroimaging and Neurochemistry of Autism

Chugani, D. C. (2012) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2011.10.002 · Cited by 44 · see citing works

Blood Serotonin Levels in Adults, Autistic and Non-Autistic Children—With a Comparison of Different Methodologies

Badcock, N. R., Spence, J. G., & Stern, L. M. (1987) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456328702400613 · Cited by 41 · see citing works

Low Platelet-Poor Plasma Levels of Serotonin in Adult Autistic Patients

Spivak, B., Golubchik, P., Mozes, T., Vered, Y., Nechmad, A., Weizman, A., & Strous, R. D. (2004) · Neuropsychobiology · doi:10.1159/000079108 · Cited by 40 · see citing works

Kinetics of3H-Serotonin uptake by platelets in infantile autism and developmental language disorder (including five pairs of twins)

Katsui, T., Okuda, M., Usuda, S., & Koizumi, T. (1986) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01531579 · Cited by 39 · see citing works

Whole-blood serotonin and cognitive functioning in autistic individuals and their first-degree relatives

Cuccaro, M. L., Wright, H. H., Abramson, R. K., Marsteller, F., & Valentine, J. (1993) · Journal of Neuropsychiatry · doi:10.1176/jnp.5.1.94 · Cited by 38 · see citing works

Platelet size, number, and serotonin content in blood of autistic, childhood schizophrenic, and normal children

Geller, E., Yuwiler, A., Freeman, B. J., & RITVO, E. R. (1988) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02211822 · Cited by 34 · see citing works

Brief Report: Platelet-Poor Plasma Serotonin in Autism

Anderson, G. M., Hertzig, M. E., & McBride, P. (2011) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1371-1 · Cited by 32 · see citing works

Experimental Models in Serotonin Transporter Research

(2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511729935 · Cited by 29 · see citing works

Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication

Minderaa, R. B., Anderson, G. M., Volkmar, F. R., Harcherick, D., Akkerhuis, G. W., & Cohen, D. J. (1989) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212724 · Cited by 28 · see citing works

Stem cells and modeling of autism spectrum disorders

Freitas, B. C. G., Trujillo, C. A., Carromeu, C., Yusupova, M., Herai, R. H., & Muotri, A. R. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2012.09.017 · Cited by 27 · see citing works

Platelet 5-HT2 serotonin receptor binding sites in autistic children and their first-degree relatives

Perry, B. D., Cook, E. H., LEVENTHAL, B. L., Wainwright, M. S., & Freedman, D. X. (1991) · Biological Psychiatry · doi:10.1016/0006-3223(91)90165-i · Cited by 20 · see citing works

The platelet‐poor plasma 5‐HT response to carbohydrate rich meal administration in adult autistic patients compared with normal controls

Vered, Y., Golubchik, P., Mozes, T., Strous, R. D., Nechmad, A., Mester, R., Weizman, A., & Spivak, B. (2003) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.489 · Cited by 15 · see citing works

Platelet Vesicular Monoamine Transporter 2 Density in the Disruptive Behavior Disorders

Zalsman, G., Aslanov-Farbstein, D., Rehavi, M., Roz, N., Vermeiren, R. R. J. M., Laor, N., Weizman, A., & Toren, P. (2011) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2010.0148 · Cited by 10 · see citing works

[Platelet serotonin concentrations in autistic children and members of their families].

de Villard, R., Flachaire, E., Jm, T., Jean Dalery, A., Maillet, J., Chauvin, C., Quincy, C., & Renaud, B. (1986) · PubMed · Cited by 5 · see citing works

Developmental roles of the serotonin transporter

Persico, A. M. (2010) · Cited by 3 · see citing works

Untitled work

Price (1999) · doi:10.1002/1531-8249(199903)45:3

Rodent models in neuroscience research: is it a rat race?

Ellenbroek, B., & Youn, J. (2016) · Disease Models & Mechanisms · doi:10.1242/dmm.026120 · Cited by 627 · see citing works

The serotonin system in autism spectrum disorder: From biomarker to animal models

Muller, C. L., Anacker, A. M. J., & Veenstra-VanderWeele, J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.11.010 · Cited by 531 · see citing works

Candidate biomarkers in psychiatric disorders: state of the field

Abi‐Dargham, A., Moeller, S. J., Ali, F., DeLorenzo, C., Domschke, K., Horga, G., Jutla, A., Kotov, R., Paulus, M. P., Rubio, J. M., et al. (2023) · World Psychiatry · doi:10.1002/wps.21078 · Cited by 390 · see citing works

Composition of gut microbiota in children with autism spectrum disorder: a systematic review and meta-analysis

Iglesias-Vázquez, L., Van Ginkel Riba, G., Arija, V., & Canals, J. (2020) · Nutrients · doi:10.3390/nu12030792 · Cited by 352 · see citing works

Autism spectrum disorder: Consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology

Howes, O. D., Rogdaki, M., Findon, J. L., Wichers, R. H., Charman, T., King, B. H., Loth, E., McAlonan, G. M., McCracken, J. T., Parr, J. R., et al. (2018) · Journal of Psychopharmacology · doi:10.1177/0269881117741766 · Cited by 342 · see citing works

The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health.

Appleton, J. (2018) · Europe PMC (PubMed Central) · Cited by 337 · see citing works

The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders

Loth, E., Charman, T., Mason, L., Tillmann, J., Jones, E. J. H., Wooldridge, C., Ahmad, J., Auyeung, B., Brogna, C., Ambrosino, S., et al. (2017) · Molecular Autism · doi:10.1186/s13229-017-0146-8 · Cited by 299 · see citing works

Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder

Luna, R. A., Oezguen, N., Balderas, M., Venkatachalam, A., Runge, J. K., Versalovic, J., Veenstra-VanderWeele, J., Anderson, G. M., Savidge, T., & Williams, K. C. (2017) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2016.11.008 · Cited by 295 · see citing works

The Neurochemistry of Autism

Marotta, R., Risoleo, M. C., Messina, G., Parisi, L., Carotenuto, M., Vetri, L., & Roccella, M. (2020) · Brain Sciences · doi:10.3390/brainsci10030163 · Cited by 279 · see citing works

Environmental risk factors and biomarkers for autism spectrum disorder: an umbrella review of the evidence

Kim, J. Y., Son, M. J., Son, C. Y., Radua, J., Eisenhut, M., Gressier, F., Koyanagi, A., Carvalho, A. F., Stubbs, B., Solmi, M., et al. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30181-6 · Cited by 271 · see citing works

Head circumference and brain size in autism spectrum disorder: A systematic review and meta-analysis

Sacco, R., Gabriele, S., & Persico, A. M. (2015) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2015.08.016 · Cited by 253 · see citing works

The Gut Microbiota and Dysbiosis in Autism Spectrum Disorders

Hughes, H. K., Rose, D., & Ashwood, P. (2018) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-018-0887-6 · Cited by 225 · see citing works

Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions

Ristori, M. V., Quagliariello, A., Reddel, S., Ianiro, G., Vicari, S., Gasbarrini, A., & Putignani, L. (2019) · Nutrients · doi:10.3390/nu11112812 · Cited by 214 · see citing works

Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders

Carvalho, A. F., Solmi, M., Sanches, M., Machado, M. O., Stubbs, B., Ajnakina, O., Sherman, C., Sun, Y. R., Liu, C. S., Brunoni, A. R., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0835-5 · Cited by 204 · see citing works

Changes in the Gut Microbiota of Children with Autism Spectrum Disorder

Zou, R., Xu, F., Wang, Y., Duan, M., Guo, M., Zhang, Q., Zhao, H., & Zheng, H. (2020) · Autism Research · doi:10.1002/aur.2358 · Cited by 202 · see citing works

Autistic spectrum disorders: A review of clinical features, theories and diagnosis

Fakhoury, M. (2015) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2015.04.003 · Cited by 203 · see citing works

Biomarkers in autism spectrum disorder: the old and the new

Ruggeri, B., Sarkans, U., Schumann, G., & Persico, A. M. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3290-7 · Cited by 191 · see citing works

The serotonin-N-acetylserotonin-melatonin pathway as a biomarker for autism spectrum disorders

Pagan, C., Delorme, R., Callebert, J., Goubran-Botros, H., Amsellem, F., Drouot, X., Boudebesse, C., Le Dudal, K., Ngo-Nguyen, N., Laouamri, H., et al. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.120 · Cited by 165 · see citing works

Behavioral neuroscience of autism

Takumi, T., Tamada, K., Hatanaka, F., Nakai, N., & Bolton, P. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.04.012 · Cited by 163 · see citing works

Microbiome and nutrition in autism spectrum disorder: Current knowledge and research needs

Berding, K., & Donovan, S. M. (2016) · Nutrition Reviews · doi:10.1093/nutrit/nuw048 · Cited by 146 · see citing works

Small Non-coding RNAs: New Class of Biomarkers and Potential Therapeutic Targets in Neurodegenerative Disease

Watson, C. N., Belli, A., & Pietro, V. D. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00364 · Cited by 148 · see citing works

Core Symptoms of Autism Improved After Vitamin D Supplementation

Jia, F., Wang, B., Shan, L., Xu, Z., Staal, W. G., & Du, L. (2015) · Pediatrics · doi:10.1542/peds.2014-2121 · Cited by 145 · see citing works

Biological factors underlying sex differences in neurological disorders

Loke, H., Harley, V. R., & Lee, J. (2015) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2015.05.024 · Cited by 141 · see citing works

Neural Circuits for Social Cognition: Implications for Autism

Fernández, M. C., Mollinedo-Gajate, I., & Peñagarikano, O. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.07.013 · Cited by 137 · see citing works

Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism

Ellegood, J., & Crawley, J. N. (2015) · Neurotherapeutics · doi:10.1007/s13311-015-0360-z · Cited by 132 · see citing works

The pediatric psychopharmacology of autism spectrum disorder: A systematic review - Part I: The past and the present

Persico, A. M., Ricciardello, A., Lamberti, M., Turriziani, L., Cucinotta, F., Brogna, C., Vitiello, B., & Arango, C. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110326 · Cited by 138 · see citing works

Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring

Gur, T. L., Palkar, A. V., Rajasekera, T., Allen, J., Niraula, A., Godbout, J., & Bailey, M. T. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.06.025 · Cited by 127 · see citing works

Serotonin as a link between the gut-brain-microbiome axis in autism spectrum disorders

Israelyan, N., & Margolis, K. G. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.03.020 · Cited by 122 · see citing works

The role of monoamine oxidase enzymes in the pathophysiology of neurological disorders

Jones, D. N., & Raghanti, M. A. (2021) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2021.101957 · Cited by 116 · see citing works

In Search of Biomarkers to Guide Interventions in Autism Spectrum Disorder: A Systematic Review

Parellada, M., Andreu-Bernabeu, Á., Burdeus-Olavarrieta, M., Cáceres, A. S. J., Urbiola, E., Carpenter, L. L., Kraguljac, N. V., McDonald, W. M., Nemeroff, C. B., Rodríguez, C. I., et al. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.21100992 · Cited by 123 · see citing works

Efficacy of Low-Dose Buspirone for Restricted and Repetitive Behavior in Young Children with Autism Spectrum Disorder: A Randomized Trial

Chugani, D. C., Chugani, H. T., Wiznitzer, M., Parikh, S., Evans, P., Hansen, R. L., Nass, R. D., Janisse, J. J., Dixon-Thomas, P., Behen, M. E., et al. (2015) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2015.11.033 · Cited by 114 · see citing works

The Gut Microbiota and Associated Metabolites Are Altered in Sleep Disorder of Children With Autism Spectrum Disorders

Hua, X., Zhu, J., Yang, T., Guo, M., Li, Q., Chen, J., & Li, T. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00855 · Cited by 108 · see citing works

The Crosstalk between Gut Microbiota and Nervous System: A Bidirectional Interaction between Microorganisms and Metabolome

Montagnani, M., Bottalico, L., Potenza, M. A., Charitos, I. A., Topi, S., Colella, M., & Santacroce, L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210322 · Cited by 106 · see citing works

Vitamin A improves the symptoms of autism spectrum disorders and decreases 5-hydroxytryptamine (5-HT): A pilot study

Guo, M., Zhu, J., Yang, T., Lai, X., Liu, X., Liu, J., Chen, J., & Li, T. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.11.001 · Cited by 97 · see citing works

Autism Spectrum Disorders and the Gastrointestinal Tract: Insights into Mechanisms and Clinical Relevance

Hung, L. Y., & Margolis, K. G. (2024) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-023-00857-1 · Cited by 96 · see citing works

Brief Report: Whole Blood Serotonin Levels and Gastrointestinal Symptoms in Autism Spectrum Disorder

Marler, S., Ferguson, B. J., Lee, E. B., Peters, B., Williams, K. C., McDonnell, E., Macklin, E. A., Levitt, P., Gillespie, C. H., Anderson, G. M., et al. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2646-8 · Cited by 95 · see citing works

P-cresol Alters Brain Dopamine Metabolism and Exacerbates Autism-Like Behaviors in the BTBR Mouse

Pascucci, T., Colamartino, M., Fiori, E., Sacco, R., Coviello, A., Ventura, R., Puglisi‐Allegra, S., Turriziani, L., & Persico, A. M. (2020) · Brain Sciences · doi:10.3390/brainsci10040233 · Cited by 92 · see citing works

Pathway of Maternal Serotonin to the Human Embryo and Fetus

Kliman, H. J., Quaratella, S. B., Setaro, A. C., Siegman, E. C., Subha, Z. T., Tal, R., Milano, K. M., & Steck, T. L. (2018) · Endocrinology · doi:10.1210/en.2017-03025 · Cited by 87 · see citing works

Reprint of: Serotonin as a link between the gut-brain-microbiome axis in autism spectrum disorders

Israelyan, N., & Margolis, K. G. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2018.12.023 · Cited by 87 · see citing works

Autism Spectrum Disorder and Sleep

Johnson, K., & Zarrinnegar, P. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.08.012 · Cited by 87 · see citing works

The Brain-Gut-Microbiome System: Pathways and Implications for Autism Spectrum Disorder

Chernikova, M. A., Flores, G. D., Kilroy, E., Labus, J. S., Mayer, E. A., & Aziz‐Zadeh, L. (2021) · Nutrients · doi:10.3390/nu13124497 · Cited by 89 · see citing works

Nanomaterial based electrochemical sensing of the biomarker serotonin: a comprehensive review

Khoshnevisan, K., Maleki, H., Honarvarfard, E., Baharifar, H., Gholami, M., Faridbod, F., Larijani, B. A., Majidi, R. F., & Khorramizadeh, M. R. (2019) · Microchimica Acta · doi:10.1007/s00604-018-3069-y · Cited by 85 · see citing works

Extreme enhancement or depletion of serotonin transporter function and serotonin availability in autism spectrum disorder

Garbarino, V. R., Gilman, T. L., Daws, L. C., & Gould, G. G. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.07.010 · Cited by 83 · see citing works

Autism Biomarkers: Challenges, Pitfalls and Possibilities

Anderson, G. M. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-014-2225-4 · Cited by 82 · see citing works

Drug development for Autism Spectrum Disorder (ASD): Progress, challenges, and future directions

McCracken, J. T., Anagnostou, E. A., Arango, C., Dawson, G., Farchione, T. R., Mantua, V., McPartland, J. C., Murphy, D., Pandina, G., & Veenstra-VanderWeele, J. M. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.05.010 · Cited by 87 · see citing works

Blood Markers in Detection of Autism

Stavridou, T., Driga, A. M., & Drigas, A. S. (2021) · International Journal of Recent Contributions from Engineering Science & IT (iJES) · doi:10.3991/ijes.v9i2.21283 · Cited by 81 · see citing works

The combined role of serotonin and interleukin-6 as biomarker for autism

Yang, C.-J., Liu, C.-L., Sang, B., Zhu, X.-M., & Du, Y.-J. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2014.10.011 · Cited by 80 · see citing works

Serotonin and serotonin transporter levels in autistic children

Abdulamir, H. A., Abdul‐Rasheed, O. F., & Abdulghani, E. A. (2018) · Saudi Medical Journal · doi:10.15537/smj.2018.5.21751 · Cited by 80 · see citing works

Applications of Near Infrared Photoacoustic Spectroscopy for Analysis of Human Respiration: A Review

Dumitraş, D., Petrus, M., Bratu, A., & Popa, C. (2020) · Molecules · doi:10.3390/molecules25071728 · Cited by 79 · see citing works

Recent developments in the probiotics as live biotherapeutic products (LBPs) as modulators of gut brain axis related neurological conditions

Ağagündüz, D., Bingöl, F. G., Çelik, E., Cemali, Ö., Özenir, Ç., Özoğul, F., & Capasso, R. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03609-y · Cited by 79 · see citing works

Risperidone and the 5‐ HT2A Receptor Antagonist M 100907 Improve Probabilistic Reversal Learning in BTBR T + tf / J Mice

Amodeo, D. A., Jones, J. H., Sweeney, J. A., & Ragozzino, M. E. (2014) · Autism Research · doi:10.1002/aur.1395 · Cited by 79 · see citing works

Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation

Kong, Q., Wang, B., Tian, P., Li, X., Zhao, J., Zhang, H., Chen, W., & Wang, G. (2021) · Food & Function · doi:10.1039/d0fo02375b · Cited by 78 · see citing works

A pilot study on evaluating children with autism spectrum disorder using computer games

Chen, J., Wang, G., Zhang, K., Wang, G., & Liu, L. (2018) · Computers in Human Behavior · doi:10.1016/j.chb.2018.08.057 · Cited by 82 · see citing works

Impact of Maternal Serotonin Transporter Genotype on Placental Serotonin, Fetal Forebrain Serotonin, and Neurodevelopment

Muller, C. L., Anacker, A. M. J., Rogers, T. D., Goeden, N., Keller, E. H., Forsberg, C. G., Kerr, T. M., Wender, C. L. A., Anderson, G. M., Stanwood, G. D., et al. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.166 · Cited by 76 · see citing works

The Effects of Exercise Dose on Stereotypical Behavior in Children with Autism

OLIN, S. S., McFadden, B. A., Golem, D. L., Pellegrino, J. K., Walker, A. J., Sanders, D. J., & Arent, S. M. (2017) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001197 · Cited by 76 · see citing works

Approaches to Understanding Multisensory Dysfunction in Autism Spectrum Disorder

Siemann, J. K., Veenstra‐VanderWeele, J., & Wallace, M. T. (2020) · Autism Research · doi:10.1002/aur.2375 · Cited by 74 · see citing works

Dysbiosis of Gut Fungal Microbiota in Children with Autism Spectrum Disorders

Zou, R., Wang, Y., Duan, M., Guo, M., Zhang, Q., & Zheng, H. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04543-y · Cited by 73 · see citing works

Sleep and circadian disturbances in children with neurodevelopmental disorders

Bruni, O., Breda, M., Mammarella, V., Mogavero, M. P., & Ferri, R. (2025) · Nature Reviews Neurology · doi:10.1038/s41582-024-01052-9 · Cited by 74 · see citing works

The Gut-Immune-Brain Axis in Autism Spectrum Disorders; A Focus on Amino Acids

van Sadelhoff, J. H. J., Perez Pardo, P., Wu, J., Garssen, J., van Bergenhenegouwen, J., Hogenkamp, A., Hartog, A., & Kraneveld, A. D. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00247 · Cited by 71 · see citing works

Autism spectrum disorder (ASD): Disturbance of the melatonin system and its implications

Wu, Z., Huang, S., Zou, J.-J., Wang, Q.-X., Naveed, M., Bao, H.-N., Wang, W., Fukunaga, K., & Han, F. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110496 · Cited by 72 · see citing works

Depression and Cardiovascular Disease: The Viewpoint of Platelets

Amadio, P., Zarà, M., Sandrini, L., Ieraci, A., & Barbieri, S. S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207560 · Cited by 71 · see citing works

Kynurenine Pathway in Autism Spectrum Disorders in Children

Bryn, V., Verkerk, R. M., Skjeldal, O. H., Saugstad, O. D., & Ormstad, H. (2017) · Neuropsychobiology · doi:10.1159/000488157 · Cited by 67 · see citing works

Prenatal selective serotonin reuptake inhibitor use and the risk of autism spectrum disorder in children: A systematic review and meta-analysis

Kaplan, Y. C., Arslan, E. K., Acar, S., & Sözmen, K. (2016) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.09.013 · Cited by 66 · see citing works

Serotonin transporter availability in adults with autism—a positron emission tomography study

Andersson, M., Tangen, Ä., Farde, L., Bölte, S., Halldin, C., Borg, J., & Lundberg, J. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00868-3 · Cited by 64 · see citing works

Biological Timing and Neurodevelopmental Disorders: A Role for Circadian Dysfunction in Autism Spectrum Disorders

Lorsung, E., Ramanujam, K., & Cao, R. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.642745 · Cited by 63 · see citing works

Role of the Gut Microbiota in the Pathophysiology of Autism Spectrum Disorder: Clinical and Preclinical Evidence

Roussin, L., Prince, N., Perez‐Pardo, P., Kraneveld, A. D., Rabot, S., & Naudon, L. (2020) · Microorganisms · doi:10.3390/microorganisms8091369 · Cited by 64 · see citing works

The Impact of Gut Microbiota-Derived Metabolites in Autism Spectrum Disorders

Marzal, L. N. P., Prince, N., Bajić, D., Roussin, L., Naudon, L., Rabot, S., Garssen, J., Kraneveld, A. D., & Perez‐Pardo, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221810052 · Cited by 63 · see citing works

Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

Chen, R., Davis, L. K., Guter, S. J., Wei, Q., Jacob, S., Potter, M. H., Cox, N. J., Cook, E. H., Sutcliffe, J. S., & Li, B. (2017) · Molecular Autism · doi:10.1186/s13229-017-0130-3 · Cited by 57 · see citing works

Serum cytokine levels in children with spectrum autism disorder: Differences in pro- and anti-inflammatory balance

Kordulewska, N. K., Kostyra, E., Piskorz-Ogórek, K., Moszyńska, M., Cieślińska, A., Fiedorowicz, E., & Jarmołowska, B. (2019) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2019.577066 · Cited by 58 · see citing works

Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD

Walsh, J. J., Llorach, P., Cardozo Pinto, D. F., Wenderski, W., Christoffel, D. J., Salgado, J. S., Heifets, B. D., Crabtree, G. R., & Malenka, R. C. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01091-6 · Cited by 56 · see citing works

Acute dietary tryptophan manipulation differentially alters social behavior, brain serotonin and plasma corticosterone in three inbred mouse strains

Zhang, W. Q., Smolik, C. M., Barba-Escobedo, P. A., Gamez, M., Sanchez, J. J., Javors, M. A., Daws, L. C., & Gould, G. G. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.10.024 · Cited by 56 · see citing works

A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders

Díaz‐Caneja, C. M., State, M. W., Hagerman, R. J., Jacquemont, S., Marín, Ó., Bagni, C., Umbricht, D., Simonoff, E. A., Andres-Trelles, F., Kaale, A., et al. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.02.020 · Cited by 54 · see citing works

A Randomized Double-Blind Placebo-Controlled Clinical Trial of Adjuvant Buspirone for Irritability in Autism

Ghanizadeh, A. J., & Ayoobzadehshirazi, A. (2014) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2014.09.017 · Cited by 56 · see citing works

Blood platelets: Circulating mirrors of neurons?

Canobbio, I. (2019) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12254 · Cited by 53 · see citing works

Brain hyperserotonemia causes autism-relevant social deficits in mice

Tanaka, M., Sato, A., Kasai, S., Hagino, Y., Kotajima‐Murakami, H., Kashii, H., Takamatsu, Y., Nishito, Y., Inagaki, M., Mizuguchi, M., et al. (2018) · Molecular Autism · doi:10.1186/s13229-018-0243-3 · Cited by 57 · see citing works

Symptomatic, Genetic, and Mechanistic Overlaps between Autism and Alzheimer’s Disease

Nadeem, M. S., Hosawi, S. B. I., Alshehri, S., Ghoneim, M. M., Imam, S. S., Murtaza, B. N., & Kazmi, I. A. (2021) · Biomolecules · doi:10.3390/biom11111635 · Cited by 56 · see citing works

Autism: Oxytocin, serotonin, and social reward

Dölen, G. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1087875 · Cited by 51 · see citing works

An autism-associated serotonin transporter variant disrupts multisensory processing

Siemann, J. K., Muller, C. L., Forsberg, C. G., Blakely, R., Veenstra-VanderWeele, J. M., & Wallace, M. T. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.17 · Cited by 52 · see citing works

Relationships between Brain Activity, Tryptophan-Related Gut Metabolites, and Autism Symptomatology

Aziz-Zadeh, L., Ringold, S. M., Jayashankar, A., Kilroy, E., Butera, C., Jacobs, J. P., Tanartkit, S., Mahurkar-Joshi, S., Bhatt, R. R., Dapretto, M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-58459-1 · Cited by 51 · see citing works

The psychopharmacology of autism spectrum disorder and Rett syndrome

Persico, A. M., Ricciardello, A., & Cucinotta, F. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64012-3.00024-1 · Cited by 53 · see citing works

Associations between dysbiosis gut microbiota and changes of neurotransmitters and short-chain fatty acids in valproic acid model rats

Zhong, J., Lan, W.-T., Feng, Y., Li, Y., Shen, Y.-Y., Gong, J.-H., Zou, Z., & Hou, X. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1077821 · Cited by 50 · see citing works

Genetic risk factors for autism-spectrum disorders: a systematic review based on systematic reviews and meta-analysis

Wei, H., Zhu, Y., Wang, T., Zhang, X., Zhang, K., & Zhang, Z. (2021) · Journal of Neural Transmission · doi:10.1007/s00702-021-02360-w · Cited by 51 · see citing works

Maternal SSRI discontinuation, use, psychiatric disorder and the risk of autism in children: a meta‐analysis of cohort studies

Kaplan, Y. C., Arslan, E. K., Acar, S., & Sözmen, K. (2017) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13382 · Cited by 49 · see citing works

Molecular Pathology and Pharmacological Treatment of Autism Spectrum Disorder-Like Phenotypes Using Rodent Models

Kuo, H., & Liu, F. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00422 · Cited by 46 · see citing works

Research Progress in Vitamin A and Autism Spectrum Disorder

Liu, Z., Wang, J., Xu, Q., Hong, Q., Zhu, J., & Chi, X. (2021) · Behavioural Neurology · doi:10.1155/2021/5417497 · Cited by 49 · see citing works

Allergic fetal priming leads to developmental, behavioral and neurobiological changes in mice

Schwartzer, J. J., Careaga, M., Chang, C., Onore, C. E., & Ashwood, P. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.40 · Cited by 47 · see citing works

Blood platelet research in autism spectrum disorders: In search of biomarkers

Padmakumar, M., Raes, E. V., Geet, C. V., & Freson, K. (2019) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12239 · Cited by 47 · see citing works

The CHD8/CHD7/Kismet family links blood-brain barrier glia and serotonin to ASD-associated sleep defects

Coll-Tané, M., Gong, N. N., Belfer, S. J., van Renssen, L. V., Kurtz‐Nelson, E. C., Szuperák, M., Eidhof, I., van Reijmersdal, B., Terwindt, I., Durkin, J., et al. (2021) · Science Advances · doi:10.1126/sciadv.abe2626 · Cited by 47 · see citing works

Evaluating the Potential Use of Serotonergic Psychedelics in Autism Spectrum Disorder

Markopoulos, A., Inserra, A., De Gregorio, D., & Gobbi, G. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.749068 · Cited by 46 · see citing works

Pathophysiological Studies of Monoaminergic Neurotransmission Systems in Valproic Acid-Induced Model of Autism Spectrum Disorder

Kuo, H., & Liu, F. (2022) · Biomedicines · doi:10.3390/biomedicines10030560 · Cited by 45 · see citing works

Decreased aggression and increased repetitive behavior in Pten haploinsufficient mice

Clipperton‐Allen, A. E., & Page, D. T. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12192 · Cited by 46 · see citing works

Supplement intervention associated with nutritional deficiencies in autism spectrum disorders: a systematic review

Li, Y., Li, Y., & Xiang, D.-X. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1528-6 · Cited by 52 · see citing works

Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders

Ormstad, H., Bryn, V., Verkerk, R. M., Skjeldal, O. H., Halvorsen, B. L., Saugstad, O. D., Isaksen, J., & Maes, M. H. J. (2018) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527317666180720163221 · Cited by 43 · see citing works

Genetic and neural mechanisms of sleep disorders in children with autism spectrum disorder: a review

Ji, Q., Li, S., Zhao, J.-B., Xiong, Y., Du, X., Wang, C.-X., Lu, L., Tan, J.-Y., & Zhu, Z.-R. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1079683 · Cited by 41 · see citing works

Influence of Prenatal Drug Exposure, Maternal Inflammation, and Parental Aging on the Development of Autism Spectrum Disorder

Sato, A., Kotajima‐Murakami, H., Tanaka, M., Katoh, Y., & Ikeda, K. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.821455 · Cited by 42 · see citing works

Heritability of the melatonin synthesis variability in autism spectrum disorders

Benabou, M., Rolland, T., Leblond, C. S., Millot, G. A., Huguet, G., Delorme, R., Leboyer, M., Pagan, C., Callebert, J., Maronde, E., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-18016-3 · Cited by 39 · see citing works

Microbiota, Immune System and Autism Spectrum Disorders: An Integrative Model towards Novel Treatment Options

Carpita, B., Marazziti, D., Palego, L., Giannaccini, G., Betti, L., & Dell’Osso, L. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190328151539 · Cited by 40 · see citing works

Addressing the Genetics of Human Mental Health Disorders in Model Organisms

McCammon, J. M., & Sive, H. L. (2015) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090314-050048 · Cited by 40 · see citing works

Multidisciplinary and Comparative Investigations of Potential Psychobiotic Effects of Lactobacillus Strains Isolated From Newborns and Their Impact on Gut Microbiota and Ileal Transcriptome in a Healthy Murine Model

Beck, B. R., Park, G.-S., Jeong, D. Y., Lee, Y. H., Im, S., Song, W. H., & Kang, J. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00269 · Cited by 38 · see citing works

Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder

Murakami, Y., Imamura, Y., Kasahara, Y., Yoshida, C., Momono, Y., Fang, K., Sakai, D., Konishi, Y., & Nishiyama, T. (2023) · Cells · doi:10.3390/cells12071087 · Cited by 36 · see citing works

A rapid accurate procedure for the determination of serotonin in whole human blood

Yuwiler, A., Plotkin, S., Geller, E., & RITVO, E. R. (1970) · Biochemical Medicine · doi:10.1016/0006-2944(70)90010-4 · Cited by 143 · see citing works

Whole Blood Serotonin Levels and Platelet 5-HT2A Binding in Autism Spectrum Disorder

Aaron, E., Montgomery, A. K., Ren, X., Guter, S. J., Anderson, G. M., Carneiro, A. M. D., Jacob, S., Mosconi, M. W., Pandey, G. N., Cook, E. H., et al. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-03989-z · Cited by 17 · see citing works

Low Platelet-Poor Plasma Levels of Serotonin in Adult Autistic Patients

Spivak, B., Golubchik, P., Mozes, T., Vered, Y., Nechmad, A., Weizman, A., & Strous, R. D. (2004) · Neuropsychobiology · doi:10.1159/000079108 · Cited by 40 · see citing works

[Platelet serotonin as a biological marker of autism].

Levy, P. Q., & Bicho, M. (1997) · PubMed · Cited by 2 · see citing works

The relation between the serotonin level in whole blood and child autism

Wei-lin, D. (2007) · Tianjin Yike Daxue xuebao · Cited by 1 · see citing works