Cited by 384Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record.

Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

Devine, D P, Leone, P, Pocock, D, Wise, R A·1993·The Journal of Pharmacology and Experimental Therapeutics

DOI 10.1016/s0022-3565(25)39324-9

Open this paper in CoChat — free account

Abstract

In vivo microdialysis was used to assess the involvement of ventral tegmental area (VTA) mu, delta, and kappa opioid receptors in modulation of basal extracellular ventral striatal dopamine (DA) and DA-metabolite concentrations. Independent groups of chloral hydrate-anesthetized rats were given VTA microinjections of selective opioid agonists, and extracellular ventral striatal DA and DA-metabolite concentrations were assayed using HPLC. VTA microinjections of [D-Ala2, N-Me-Phe4-Gly5-ol]-enkephalin (DAMGO; a mu agonist) and [D-Pen2, D-Pen5]-enkephalin (DDDPE; a delta agonist) each caused dose-orderly increases in ventral striatal DA and DA-metabolite concentrations. The effective concentrations of DPDPE were 100- to 1000-fold higher than the effective concentrations of DAMGO. VTA microinjections of (trans-(dl)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclo-hexyl]- benzeneacetamide) methane sulfonate hydrate (U-50,488H); a kappa agonist) failed to alter ventral striatal DA concentrations at any dose tested, but subsequent systemic injections significantly decreased DA and DA-metabolite concentrations. Pretreatment with VTA microinjections of 17-cyclopropylmethyl-6,7-dehydro-4,5-epoxy-3,14-dihydroxy-6,7,2',3'- indolmorphinan hydrochloride (naltrindole; a delta antagonist) (delta antagonist) antagonized VTA DPDPE-mediated increases in ventral striatal DA and DA-metabolite concentrations but failed to antagonize VTA DAMGO-mediated increases. Pretreatment with D-Pen-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP; a mu antagonist) antagonized VTA DAMGO-mediated increases but failed to antagonize VTA DPDPE-mediated increases. Thus both mu and delta receptor agonist appear capable of increasing ventral striatal DA and DA-metabolite concentrations through selective actions on their preferred class of opioid receptors in the VTA. The increases in ventral striatal DA and DA-metabolite concentrations that are seen after systemic treatment with kappa opioid agonists appear not to involve VTA opioid receptors.

Integrity signals

Registry

Crossref · 10.1016/s0022-3565(25)39324-9

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Still being checked.

Sorted by citations

Items 301–384 of 384

Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction
Massaly, N., Markovic, T., Creed, M. C., Al‐Hasani, R., Cahill, C. M., & Morón, J. A. (2021) · International review of neurobiology · doi:10.1016/bs.irn.2020.09.002 · Cited by 12
Stress, Opioid Peptides, and Their Receptors
Przewłocki, R. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50014-7 · Cited by 7
Delta Opioids and Substance Abuse
Negus, S. S. (2003) · CRC Press eBooks · doi:10.1201/9780203025765.ch23 · Cited by 8
Spatial information processing consequences of DAMGO injections into the dorsal striatum
Holahan, M. R., Nichol, J., & Madularu, D. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.05.001 · Cited by 7
Advancing Addiction Treatment: What Can We Learn from Animal Studies?
Wu, P. H., & Schulz, K. M. (2012) · ILAR Journal · doi:10.1093/ilar.53.1.4 · Cited by 7
Effects of chronic naltrexone treatment in rats on place preference and locomotor activation after acute administration of cocaethylene or ethanol plus cocaine
Sable, H. J. K., White, S. L., & Steinpreis, R. E. (2004) · Alcohol · doi:10.1016/j.alcohol.2004.04.004 · Cited by 7
The κ-opioid receptor agonist U-69593 prevents cocaine-induced phosphorylation of DARPP-32 at Thr34 in the rat brain
D’Addario, C., Benedetto, M. D., Candeletti, S., & Romualdi, P. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.01.014 · Cited by 7
Can the incentive-sensitization theory of addiction incorporate addiction to opioid drugs?
Robinson, T. E., & Berridge, K. C. (2026) · Psychopharmacology · doi:10.1007/s00213-025-07001-8 · Cited by 6
Nalmefene, a mu opioid receptor antagonist/kappa opioid receptor partial agonist, potentiates cocaine motivation but not intake with extended access self-administration in adult male mice
Windisch, K. A., Morochnik, M., Reed, B., & Kreek, M. J. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108590 · Cited by 7
Glutamate and Opioid Antagonists Modulate Dopamine Levels Evoked by Innately Attractive Male Chemosignals in the Nucleus Accumbens of Female Rats
Sánchez-Catalán, M. J., Orrico‐Sánchez, A., Hipólito, L., Zornoza, T., Polache, A., Lanuza, E., Martínez‐Garciá, F., Granero, L. M., & Agustín‐Pavón, C. (2017) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2017.00008 · Cited by 6
Differential Time Course of Effects of κ-Opioid Agonist Treatment on Dynorphin A Levels and κ-Opioid Receptor Density
D’Addario, C., Benedetto, M. D., Izenwasser, S., Candeletti, S., & Romualdi, P. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:24:2:307 · Cited by 6
Changes in Proenkephalin mRNA expression in forebrain areas after amphetamine-induced behavioural sensitization
Morales‐Mulia, M., Panayi, F., Lambás‐Señas, L., Scarna, H., & Méndez, M. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.04.019 · Cited by 6
Involvement of opioid receptors in N-Methyl-d-aspartate-induced arterial hypertension in periaqueductal gray matter
Maione, S., Leyva, J., Pallotta, M., Berrino, L., de Novellis, V., & Rossi, F. (1995) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00169068 · Cited by 6
Genetic and epigenetic effects on couple adjustment in context of romantic relationship: A scoping systematic review
Khani, P., Dezfouli, M. A., Nasri, F., Rahemi, M., Ahmadloo, S., Afkhami, H., Saeidi, F., Tereshchenko, S. Y., Bigdeli, M. R., & Modarressi, M. H. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1002048 · Cited by 8
Threonine-53 Phosphorylation of Dopamine Transporter Dictates κ-Opioid Receptor-Mediated Locomotor Suppression, Aversion, and Cocaine Reward
Varman, D. R., Ramamoorthy, S., & Jayanthi, L. D. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0171-25.2025 · Cited by 5
Implication of KCC2 in the sensitization to morphine by chronic ethanol treatment in mice
Shibasaki, M., Tsuyuki, T., Ando, K., Otokozawa, A., Udagawa, Y., Watanabe, K., Shibasaki, Y., Mori, T., & Suzuki, T. (2013) · Synapse · doi:10.1002/syn.21688 · Cited by 5
Asymmetric Generalization and Interaction Profiles in Rhesus Monkeys Discriminating Intravenous Cocaine or Intravenous Heroin from Vehicle
Platt, D. M., Rowlett, J. K., & Spealman, R. D. (2009) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.109.162941 · Cited by 5
Region-dependent G-protein activation by μ-, δ1- and δ2-opioid receptor agonists in the brain: Comparison between the midbrain and forebrain
Tsuji, M., Narita, M., Mizoguchi, H., Narita, M., Ohsawa, M., Kamei, J., Nagase, H., Takeda, H., Matsumiya, T., & Tseng, L. F. (1999) · Life Sciences · doi:10.1016/s0024-3205(99)00422-1 · Cited by 5
Landmark publications in Psychopharmacology: the first 40 years
Miczek, K. A. (2001) · Psychopharmacology · doi:10.1007/s002130000675 · Cited by 5
Aberrant type 2 dopamine and mu-opioid receptor availability in autism spectrum disorder
Noppari, T., Tuisku, J., Lukkarinen, L., Tani, P., Lindberg, N., Saure, E., Lauerma, H., Tiihonen, J., Hirvonen, J., Helin, S., et al. (2025) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-025-07620-5 · Cited by 7
Relevance of the Kappa Dynorphin System to Schizophrenia and Its Therapeutics
Abi‐Dargham, A. (2021) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20210015 · Cited by 4
Involvement of the endogenous opioid system in the beneficial influence of physical exercise on amphetamine-induced addiction parameters
Rosa, H. Z., Segat, H. J., Barcelos, R. C. S., Roversi, K., Rossato, D. R., de Brum, G. F., & Bürger, M. E. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173000 · Cited by 5
Neurobiología de la dependencia alcohólica
Pérez-Rial, S., Ortiz, S., & Manzanares, J. (2003) · Trastornos Adictivos · doi:10.1016/s1575-0973(03)70100-7 · Cited by 4
Lack of effect of κ-opioid receptor agonism on long-term methamphetamine-induced neurotoxicity in rats
Johnson‐Davis, K. L., Hanson, G. R., & Keefe, K. A. (2003) · Neurotoxicity Research · doi:10.1007/bf03033385 · Cited by 4
Stress and Opioid Systems
Przewłocki, R., & Almeida, O. F. X. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00008-0 · Cited by 4
Molekularne podstawy działania wybranych substancji psychoaktywnych
Bijoch, Ł., Pękała, M., & Beroun, A. (2021) · Postępy Biochemii · doi:10.18388/pb.2021_376 · Cited by 5
Imaging Human Brain Opioid Receptors: Applications to Substance Use Disorders
Greenwald, M. K., & Steinmiller, C. L. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-197-0_3 · Cited by 3
Up-regulation of dopamine D1-receptors in the brain of 28-day-old rats exposed to the delta (δ) opioid agonist SNC80 during the preweaning period
Shieh, G.-J., Ravis, W. R., & Walters, D. E. (1997) · Developmental Brain Research · doi:10.1016/s0165-3806(97)81798-1 · Cited by 3
Addiction
Wise, R. A. (2002) · Wiley eBooks · doi:10.1002/0471214426.pas0319 · Cited by 3
Self-citation
The effect of nucleus accumbens lesions on appetite, sexual function, and nicotine dependence in recovering heroin addicts
Wang, Y., Zhu, J., Chen, L., Liu, Y., Li, Q., Yang, W., Li, W., Zhao, L., Gold, M. S., Sun, J., et al. (2013) · Translational Neuroscience · doi:10.2478/s13380-013-0146-x · Cited by 3
La neurobiologie de l'addiction
Brust, J. C. M. (2007) · Elsevier eBooks · doi:10.1016/b978-2-84299-712-0.50002-4 · Cited by 2
Structural and Functional Neuroimaging of the Effects of Opioids
Nutt, D., & Daglish, M. R. C. (2002) · Humana Press eBooks · doi:10.1007/978-1-59259-165-7_15 · Cited by 2
The Role of Delta Opioid Receptors in Ethanol Consumption and Seeking: Implications for New Treatments for Alcohol Use Disorders
Carsten, K., & Selena, E. (2012) · InTech eBooks · doi:10.5772/32239 · Cited by 1
Cocaine, β-Endorphin, and δ-Opioid Receptors
Yadid, G., Roth‐Deri, I., & Green-Sadan, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803750-8.00047-6 · Cited by 2
Delta opioid receptors affect acoustic features of song during vocal learning in zebra finches
Singh, U. A., & Iyengar, S. (2025) · BMC Neuroscience · doi:10.1186/s12868-025-00927-x · Cited by 1
Les opioïdes
Brust, J. C. M. (2007) · Elsevier eBooks · doi:10.1016/b978-2-84299-712-0.50003-6 · Cited by 1
Environmental Modulation of Drug Taking
Badiani, A., Caprioli, D., Testa, A., Luca, M. T. D., & Celentano, M. (2010) · Neuromethods · doi:10.1007/978-1-60761-934-5_11 · Cited by 1
Characteristics of the runway model of intracranial self-stimulation behavior and comparison with other motivated behaviors.
Esumi, S., Kawasaki, Y., Gomita, Y., Kitamura, Y., & Sendo, T. (2014) · PubMed · doi:10.18926/amo/52893 · Cited by 1
Opioidergic compounds: preclinical data
Hyytiä, P. (2006) · Birkhäuser-Verlag eBooks · doi:10.1007/3-7643-7305-9_11 · Cited by 1
Opioids
Brust, J. C. M. (2004) · Elsevier eBooks · doi:10.1016/b978-0-7506-7313-6.50007-6 · Cited by 1
Opioid Receptor Ligands
McCurdy, C. R., & Prisinzano, T. E. (2021) · Burger's Medicinal Chemistry and Drug Discovery · doi:10.1002/0471266949.bmc251.pub2 · Cited by 1
Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse
Neumeyer, J. L., Mello, N. K., Negus, S. S., & Bidlack, J. M. (2000) · Pharmacochemistry library · doi:10.1016/s0165-7208(00)80039-2 · Cited by 1
Potential Utility of Kappa Ligands in the Treatment of Mood Disorders
Carlezon, W. A., & Cohen, B. M. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-197-0_22 · Cited by 1
Behavioural Pharmacology of Novel Kappa Opioid Compounds
Morani, A. S. (2011) · Figshare · doi:10.26686/wgtn.17011409.v1
Sexual behavior causes activation and functional alterations of mesolimbic systems : neurobiology of motivation and reward.
Balfour, M. E. (2003) · OhioLink ETD Center (Ohio Library and Information Network)
Effects of chronic nicotine on behavioural and neurochemical responses to morphine
Kivinummi, T. (2009) · Työväentutkimus Vuosikirja
Role of the endogenous opioid system in addiction to alcohol and cocaine
Burattini, C. (2007) · AMS Dottorato Institutional Doctoral Theses Repository (University of Bologna) · doi:10.6092/unibo/amsdottorato/444
enero-junio de 2014
Stoa, R. (2014) · Dialnet (Universidad de la Rioja) · doi:10.25009/s.2014.9.850
Activation of the Naloxone-sensitive Sigma Receptor by (+)-Morphine or (−)-Morphine Attenuates (−)-Morphine-induced Analgesia and Addiction
Tseng, L. F. (2013) · Journal of Experimental & Clinical Medicine · doi:10.1016/j.jecm.2013.08.002
EFFECTS OF JOINT COCAINE AND ETHANOL ON THE BRAIN OPIOID SYSTEMS
Rosin, Å. (2005) · Figshare
Brain opioid mechanisms in amphetamine induced behaviours
Häggkvist, J. (2009) · Figshare
The rewarding and cognitive effects of corticosterone in mice
Ebada, M. E. (2012) · Nottingham ePrints (University of Nottingham)
Étude du rôle de la dopamine et de la sérotonine dans l’effet atténuateur des antipsychotiques et de l’OSU-6162 sur la récompense induite par la stimulation du faisceau médian prosencéphalique chez le rongeur
Benaliouad, F. (2009) · doi:10.71781/30069
Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 313 Maternal Separation in Rats An Experimental Model for Long-Term Effects of Early Life Experiences on Neurochemistry, Voluntary Ethanol Intake and Exploration and Risk Assessment Behavior
Roman, E. (2004)
Role of Cerebral Dopamine and Noradrenaline in Locomotor Sensitization to Morphine in Mice
Airio, J. (1999) · Työväentutkimus Vuosikirja
Alcohol consumption in male rats increases after sexual interaction
González, M. H., Franco-López, M. E., Mancilla, L. E. F., & Guevara, M. Á. (2014) · e-CUCBA · doi:10.32870/e-cucba.v1i1.33
The dynorphin/kappa-opioid system of the brain as a promising target for therapy for dependence on psychoactive substances
Шагиахметов, Ф. Ш., Proskuryakova, T. V., & Shamakina, I. Y. (2015) · Neurochemical Journal · doi:10.1134/s1819712415040157 · Cited by 1
The K + -Cl − Cotransporter KCC2 and Zolpidem
Shibasaki, M., Mori, T., & Suzuki, T. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800634-4.00031-7
The Neural Encoding of Reward in the Striatal-Pallidal Circuitry
Chan, C. L. (2017) · e-Publications@Marquette (Marquette University)
Kappa Opioid Regulation of Dopamine in Dysphoria and Addiction
Ehrich, J. M. (2015) · ResearchWorks at the University of Washington (University of Washington)
Neurobiología de la dependencia alcohólica Neurobiology of alcohol dependence
Pérez-Rial, S., Ortiz, S., & Manzanares, J. (2016)
Molecular Characterization of the Opioid Receptors: Design, Development, and Preclinical Evaluation of Salvinorin A-Based Molecular Probes.
Keasling, A. W. (2017)
Effect Of Inflammatory Pain On Alcohol-Induced Dopamine Release In The Nucleus Accumbens: Behavioural Implications In Rat ModelsPreprint
Campos‐Jurado, Y., Lorente, J. D., González-Romero, J. L., Granero, L. M., Polache, A., & Hipólito, L. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/862318
The role of oxytocin, testosterone and cortisol in affiliation and bonding in male Barbary macaqaues
Rincon, A. V. (2020) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-7818
Effects of the selective dopamine D 3 receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in micePreprint
Botz-Zapp, C. A., Foster, S. L., Pulley, D. M., Hempel, B., Bi, G.-H., Xi, Z.-X., Newman, A. H., Weinshenker, D., & Manvich, D. F. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.07.029918
Behavioural Pharmacology of Novel Kappa Opioid Compounds
Morani, A. S. (2011) · doi:10.26686/wgtn.17011409
Faculty Opinions recommendation of Opioid-galanin receptor heteromers mediate the dopaminergic effects of opioids.
Wise, R. A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.735398607.793560140
Self-citation
Faculty Opinions recommendation of Presynaptic opioid and nicotinic receptor modulation of dopamine overflow in the nucleus accumbens.
Berridge, K. C. (2008) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1102183.558183
AI Derived Therapeutic Development for the Treatment of Opioid Use DisorderPreprint
Lallai, V., Martin, A., Fowler, J. P., Bautista, M. R., Mogul, A. S., Cheepluesak, J. E., Mirzaei, S., Jenkins, I. D., Lakey, J. R. T., Tinder, R., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.26.579391
Dopamine D2R and opioid MOR availability in autism spectrum disorderPreprint
Noppari, T., Tuisku, J., Lukkarinen, L., Tani, P., Lindberg, N., Saure, E., Lauerma, H., Tiihonen, J., Hirvonen, J., Helin, S., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.09.588651
Dopamine transporter threonine-53 phosphorylation dictates kappa opioid receptor mediated locomotor suppression and conditioned place aversion via transporter upregulationPreprint
Varman, D. R., Jayanthi, L. D., & Ramamoorthy, S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.09.593368
Kappa opioid receptors delay sucrose self-administration by modulating dopamine ramps before operant respondingPreprint
Wallace, C. W., Lopes, E. F., Holleran, K. M., & Jones, S. R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.23.684229
The functional role of opioidergic system within the ventral tegmental area and the dentate gyrus of hippocampus in modulation of the persistent inflammatory pain in the rats
Saghafi, M., Azizbeigi, R., & Haghparast, A. (2026) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2026.05.007
Opioid Antagonists as a Potential Novel Class of Psychopharmacological Agents for Management of Anhedonia
Шагиахметов, Ф. Ш., Krupitsky, E. M., Shamakina, I. Y., Anokhin, P. K., Arkus, M. L., & Scheidegger, Y. M. (2026) · V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY · doi:10.31363/2313-7053-2026-1-1179
Chronic morphine differentially impacts glutamatergic synaptic plasticity in the ventral tegmental area of adult versus adolescent mice
Edwards, J. G., Ostlund, I., & Gunten, M. V. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.110925
Opioids, palatable feeding and exercise
Ugur, M. (2019) · theses.fr (ABES) · doi:10.70675/96430ef5z0268z4e14za024z45e7fa53eda6
AI-derived therapeutic development of a serotonin receptor–targeting drug for the treatment of opioid use disorder
Lallai, V., Kho, S. C., Martin, A. C., Fowler, J. P., Roach, M. L., Wang, K. Z., Laumann, K. N., Morrison, T. G., Palaniappan, M., Bautista, M. R., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2516807123
Behavioral and molecular adaptations following sucrose bingeing : insight into neuroinflammatory markers
Awad, G. (2022) · theses.fr (ABES) · doi:10.70675/9224805cz0c14z4606za1aczb2b4e532135b
Opioid Antagonists for Hedonic Liberation—Not All Is Over
Шагиахметов, Ф. Ш., Shamakina, I. Y., Kokhan, V. S., & Krupitsky, E. M. (2026) · Future Pharmacology · doi:10.3390/futurepharmacol6020026
Separate and concurrent use of methamphetamine and fentanyl: behavioral and neurobiological consequences
Madden, J. T., Clark, B. J., Hamilton, D. A., & Pentkowski, N. S. (2026) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2026.1966221
BindingDB Entry 5717: The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family.
BindingDB (2013) · UC San Diego · doi:10.7270/q2qj7fwb
BindingDB Entry 5511: Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties.
BindingDB (2012) · UC San Diego · doi:10.7270/q22z144q
BindingDB Entry 5366: 8-Carboxamidocyclazocine: a long-acting, novel benzomorphan.
BindingDB (2012) · UC San Diego · doi:10.7270/q2959g3p
Association Tests of the Opioid Receptor System and Alcohol-Related Traits
Bennett, R. T. (2009) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/bw5h-qp43

Authors: Devine, D. P., Leone, P., Pocock, D., & Wise, R. A.
Affiliations: Concordia University (CA)
ORCID: Devine, D P
Leone, P
Wise, R A
Venue: The Journal of Pharmacology and Experimental Therapeutics
Publisher: Elsevier BV
Published: 1993-07
Volume: 266
Issue: 3
Pages: 1236-1246
ISSN: 0022-3565 (ISSN-L)
DOI: 10.1016/s0022-3565(25)39324-9
OpenAlex: W2108098398
Cited by: 382
References: 0
Citations by year: 2026: 7 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 9 · 2020: 8 · 2019: 10 · 2018: 5 · 2017: 10 · 2016: 7 · 2015: 10 · 2014: 7 · 2013: 13 · 2012: 10
FWCI: 3.37
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Pharmacology and Experimental Therapeutics (publishedVersion)
PubMed (publishedVersion)
PubMed
Funders: National Institute on Drug Abuse (DA1720)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: ventral tegmental area, mu-opioid receptor, delta opioid receptor, kappa opioid receptor, dopamine release, ventral striatum, dopamine metabolites, DAMGO, DPDPE, U50,488H, naltrindole, CTOP, mesolimbic dopamine system, opioid receptor selectivity, enkephalin, opioid agonists, opioid antagonists
MeSH terms: Amino Acid Sequence, Analgesics, Animals, Chromatography, High Pressure Liquid, Corpus Striatum, Dialysis, Dopamine, Enkephalins, Homovanillic Acid, Hydroxyindoleacetic Acid, Limbic System, Male, Microinjections, Molecular Sequence Data, Naltrexone, Narcotic Antagonists, Pyrrolidines, Rats, Inbred Strains, Receptors, Opioid, Tegmentum Mesencephali, 3,4-Dihydroxyphenylacetic Acid, 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer, Enkephalin, Ala(2)-MePhe(4)-Gly(5)-, Enkephalin, D-Penicillamine (2,5)-, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks