Cited by 384Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record.

Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

Devine, D P, Leone, P, Pocock, D, Wise, R A·1993·The Journal of Pharmacology and Experimental Therapeutics

DOI 10.1016/s0022-3565(25)39324-9

Open this paper in CoChat — free account

Abstract

In vivo microdialysis was used to assess the involvement of ventral tegmental area (VTA) mu, delta, and kappa opioid receptors in modulation of basal extracellular ventral striatal dopamine (DA) and DA-metabolite concentrations. Independent groups of chloral hydrate-anesthetized rats were given VTA microinjections of selective opioid agonists, and extracellular ventral striatal DA and DA-metabolite concentrations were assayed using HPLC. VTA microinjections of [D-Ala2, N-Me-Phe4-Gly5-ol]-enkephalin (DAMGO; a mu agonist) and [D-Pen2, D-Pen5]-enkephalin (DDDPE; a delta agonist) each caused dose-orderly increases in ventral striatal DA and DA-metabolite concentrations. The effective concentrations of DPDPE were 100- to 1000-fold higher than the effective concentrations of DAMGO. VTA microinjections of (trans-(dl)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclo-hexyl]- benzeneacetamide) methane sulfonate hydrate (U-50,488H); a kappa agonist) failed to alter ventral striatal DA concentrations at any dose tested, but subsequent systemic injections significantly decreased DA and DA-metabolite concentrations. Pretreatment with VTA microinjections of 17-cyclopropylmethyl-6,7-dehydro-4,5-epoxy-3,14-dihydroxy-6,7,2',3'- indolmorphinan hydrochloride (naltrindole; a delta antagonist) (delta antagonist) antagonized VTA DPDPE-mediated increases in ventral striatal DA and DA-metabolite concentrations but failed to antagonize VTA DAMGO-mediated increases. Pretreatment with D-Pen-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP; a mu antagonist) antagonized VTA DAMGO-mediated increases but failed to antagonize VTA DPDPE-mediated increases. Thus both mu and delta receptor agonist appear capable of increasing ventral striatal DA and DA-metabolite concentrations through selective actions on their preferred class of opioid receptors in the VTA. The increases in ventral striatal DA and DA-metabolite concentrations that are seen after systemic treatment with kappa opioid agonists appear not to involve VTA opioid receptors.

Integrity signals

Registry

Crossref · 10.1016/s0022-3565(25)39324-9

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Still being checked.

Sorted by citations

Items 101–200 of 384

Opioid–galanin receptor heteromers mediate the dopaminergic effects of opioids
Cai, N.-S., Quiroz, C., Bonaventura, J., Bonifazi, A., Cole, T. O., Purks, J., Billing, A. S., Massey, E. C., Wagner, M., Wish, E. D., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci126912 · Cited by 71
The effects of nucleus accumbens core and shell lesions on intravenous heroin self-administration and the acquisition of drug-seeking behaviour under a second-order schedule of heroin reinforcement
Hutcheson, D. M., Parkinson, J. A., Robbins, T. W., & Everitt, B. J. (2000) · Psychopharmacology · doi:10.1007/s002130000635 · Cited by 70
Roles of Nucleus Accumbens CREB and Dynorphin in Dysregulation of MotivationPreprint
Muschamp, J. W., & Carlezon, W. A. (2013) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a012005 · Cited by 74
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence
Clark, S. D., & Abi‐Dargham, A. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.05.012 · Cited by 68
Kappa Opioid Receptor Activation Potentiates the Cocaine-Induced Increase in Evoked Dopamine Release Recorded In Vivo in the Mouse Nucleus Accumbens
Ehrich, J. M., Phillips, P. E. M., & Chavkin, C. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.157 · Cited by 65
Mechanistic insights into nicotine withdrawal
Paolini, M., & De Biasi, M. (2011) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.07.075 · Cited by 66
Antiparkinsonian Action of a δ Opioid Agonist in Rodent and Primate Models of Parkinson's Disease
Hille, C. J., Fox, S. H., Maneuf, Y. P., Crossman, A. R., & Brotchie, J. M. (2001) · Experimental Neurology · doi:10.1006/exnr.2001.7763 · Cited by 65
Opioid Tolerance and the Emergence of New Opioid Receptor-Coupled Signaling
Gintzler, A. R., & Chakrabarti, S. (2000) · Molecular Neurobiology · doi:10.1385/mn:21:1-2:021 · Cited by 64
The effects of excitotoxic lesions of the nucleus accumbens core or shell regions on intravenous heroin self-administration in rats
Alderson, H. L., Parkinson, J. A., Robbins, T. W., & Everitt, B. J. (2000) · Psychopharmacology · doi:10.1007/s002130000634 · Cited by 67
Roles of opioid receptor subtypes in mediating alcohol‐seeking induced by discrete cues and context
Marinelli, P. W., Funk, D. R., Harding, S. E., Li, Z., Juzytsch, W., & Lê, A. D. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06851.x · Cited by 62
The role of δ‐opioid receptors in learning and memory underlying the development of addiction
Klenowski, P. M., Morgan, M., & Bartlett, S. E. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12618 · Cited by 60
μ‐Receptor agonism with alfentanil increases striatal dopamine D2 receptor binding in man
Hagelberg, N. M., Kajander, J., Någren, K., Hinkka‐Yli‐Salomäki, S., Hietala, J. A., & Scheinin, H. (2002) · Synapse · doi:10.1002/syn.10078 · Cited by 61
μ‐Opioid receptors in the ventral tegmental area are targeted to presynaptically and directly modulate mesocortical projection neurons
Svingos, A. L., Garzón, M., Colago, E. E. O., & Pickel, V. M. (2001) · Synapse · doi:10.1002/syn.1079 · Cited by 59
Effect of Enterostatin and Kappa-Opioids on Macronutrient Selection and Consumption
Ookuma, K., Barton, C., York, D. A., & Bray, G. A. (1997) · Peptides · doi:10.1016/s0196-9781(97)00029-6 · Cited by 59
Stimulatory effects of opioids
Harrison, C., Smart, D., & Lambert, D. G. (1998) · British Journal of Anaesthesia · doi:10.1093/bja/81.1.20 · Cited by 59
Basal and morphine‐evoked dopaminergic neurotransmission in the nucleus accumbens of MOR‐ and DOR‐knockout mice
Chefer, V. I., Kieffer, B. L., & Shippenberg, T. S. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02912.x · Cited by 58
Ultradian rhythms in mammalian physiology and behavior
Prendergast, B. J., & Zucker, I. (2016) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2016.07.011 · Cited by 57
Preclinical research on cocaine self-administration: environmental determinants and their interaction with pharmacological treatment
LeSage, M. G., Stafford, D. A., & Glowa, J. R. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00015-9 · Cited by 59
Mu opioid receptor modulation of somatodendritic dopamine overflow: GABAergic and glutamatergic mechanisms
Chefer, V. I., Denoroy, L., Zapata, A. G., & Shippenberg, T. S. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06827.x · Cited by 58
Ventral tegmental area opioid mechanisms and modulation of ingestive behavior
Badiani, A., Leone, P., Noel, M. B., & Stewart, J. (1995) · Brain Research · doi:10.1016/0006-8993(94)01281-l · Cited by 57
Self-citation
Naloxone attenuates incubated sucrose craving in rats
Grimm, J. W., Manaois, M., Osincup, D., Wells, B., & Buse, C. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0868-y · Cited by 56
Ventral tegmental injections of a selective μ or δ opioid enhance feeding in food-deprived rats
Noel, M. B., & Wise, R. A. (1995) · Brain Research · doi:10.1016/0006-8993(94)01442-k · Cited by 56
Self-citation
Self-Administered Heroin and Cocaine Combinations in the Rat: Additive Reinforcing Effects—Supra-Additive Effects on Nucleus Accumbens Extracellular Dopamine
Smith, J. E., Co, C., Coller, M., Hemby, S. E., & Martin, T. J. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300786 · Cited by 56
Ablation of Kappa-Opioid Receptors from Brain Dopamine Neurons has Anxiolytic-Like Effects and Enhances Cocaine-Induced Plasticity
Veer, A. V., Bechtholt, A. J., Onvani, S., Potter, D. N., Wang, Y., Liu‐Chen, L., Schütz, G., Chartoff, E. H., Rudolph, U., Cohen, B. M., et al. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.58 · Cited by 59
Role of the Nucleus Accumbens and the Striatum in the Production of Turning Behaviour in Intact Rats
Koshikawa, N. (1994) · Reviews in the Neurosciences · doi:10.1515/revneuro.1994.5.4.331 · Cited by 55
Benzodiazepine use among patients in heroin-assisted vs. methadone maintenance treatment: Findings of the German randomized controlled trial
Eiroá‐Orosa, F. J., Haasen, C., Verthein, U., Dilg, C., Schäfer, I., & Reimer, J. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.06.013 · Cited by 54
Lack of dependence and rewarding effects of deltorphin II in mu-opioid receptor-deficient mice
Hutcheson, D. M., Matthes, H. W. D., Valjent, E., Sánchez‐Blázquez, P., Rodríguez‐Díaz, M., Garzón, J., Kieffer, B. L., & Maldonado, R. J. (2001) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2001.01363.x · Cited by 54
κ-Opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration
Doyon, W. M., Howard, E. C., Shippenberg, T. S., & Gonzales, R. A. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.04.005 · Cited by 53
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion
Margolis, E. B., & Karkhanis, A. N. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.104504 · Cited by 56
Shell/core differences in mu- and delta-opioid receptor modulation of dopamine efflux in nucleus accumbens
Hipólito, L., Sánchez-Catalán, M. J., Zanolini, I., Polache, A., & Granero, L. M. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.05.012 · Cited by 52
Motivational effects of opiates in conditioned place preference and aversion paradigm—a study in three inbred strains of mice
Solecki, W., Turek, A., Kubik, J., & Przewłocki, R. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1672-7 · Cited by 52
Differences in the Peripheral Levels of ??-endorphin in Response to Alcohol and Stress as a Function of Alcohol Dependence and Family History of Alcoholism
Dai, X., Thavundayil, J., & Gianoulakis, C. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000187599.17786.4a · Cited by 52
Electrochemical evidence of increased dopamine transmission in prefkontal cortex and nucleus accumbens elicited by ventral tegmental μ‐opioid receptor activation in freely behaving rats
Noel, M. B., & Gratton, A. P. (1995) · Synapse · doi:10.1002/syn.890210204 · Cited by 51
Inhibition of opioid systems in the hypothalamus as well as the mesolimbic area suppresses feeding behavior of mice
Ikeda, H., Ardianto, C., Yonemochi, N., Yang, L., Ohashi, T., Ikegami, M., Nagase, H., & Kamei, J. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.10.002 · Cited by 50
Brain Regional Fos Expression Elicited by the Activation of μ- but not δ-Opioid Receptors of the Ventral Tegmental Area: Evidence for an Implication of the Ventral Thalamus in Opiate Reward
David, V., Matifas, A., Gavello-Baudy, S., Decorte, L., Kieffer, B. L., & Cazala, P. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301529 · Cited by 50
Activation of mesolimbic dopamine neurons during novel and daily limited access to palatable food is blocked by the opioid antagonist LY255582
Sahr, A. E., Sindelar, D. K., Alexander-Chacko, J. T., Eastwood, B. J., Mitch, C. H., & Statnick, M. A. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00390.2007 · Cited by 50
The dynamic interaction between pain and opioid misuse
Wilson‐Poe, A. R., & Morón, J. A. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13873 · Cited by 49
Ghrelin receptor antagonism of fentanyl‐induced conditioned place preference, intravenous self‐administration, and dopamine release in the nucleus accumbens in rats
Šustková-Fišerová, M., Puskina, N., Havlickova, T., Lapka, M., Syslová, K., Pohorala, V., & Charalambous, C. (2019) · Addiction Biology · doi:10.1111/adb.12845 · Cited by 50
Locomotor stimulant effects of acute and repeated intrategmental injections of salsolinol in rats: role of μ-opioid receptors
Hipólito, L., Sánchez-Catalán, M. J., Zornoza, T., Polache, A., & Granero, L. M. (2010) · Psychopharmacology · doi:10.1007/s00213-009-1751-9 · Cited by 49
[18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses
Mulholland, G. K., Wieland, D. M., Kilbourn, M. R., Frey, K. A., Sherman, P. S., Carey, J. E., & Kuhl, D. E. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199811)30:3 · Cited by 100
Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner
Tejeda, H. A., Natividad, L. A., Orfila, J. E., Torres, O. V., & O’Dell, L. E. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2752-7 · Cited by 47
Motor stimulant effects of ethanol and acetaldehyde injected into the posterior ventral tegmental area of rats: role of opioid receptors
Sánchez-Catalán, M. J., Hipólito, L., Zornoza, T., Polache, A., & Granero, L. M. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1495-6 · Cited by 48
Bremazocine reduces unrestricted free-choice ethanol self-administration in rats without affecting sucrose preference
Nestby, P., Schoffelmeer, A. N. M., Homberg, J. R., Wardeh, G., Vries, T. J. D., Mulder, A. H., & Vanderschuren, L. J. M. J. (1999) · Psychopharmacology · doi:10.1007/s002130050894 · Cited by 48
Morphine-Induced c-fos mRNA Expression in Striatofugal Circuits: Modulation by Dose, Environmental Context, and Drug History
Ferguson, S. M., Thomas, M. J., & Robinson, T. E. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300465 · Cited by 48
Effect of chronic social stress on delta-opioid receptor function in the rat.
Pohorecky, L. A., Skiandos, A., Zhang, X., Rice, K. C., & Benjamin, D. (1999) · PubMed · Cited by 48
Molecular and Neuroanatomical Properties of the Endogenous Opioid System: Implications for Treatment of Opiate Addiction
Akil, H., Meng, F., Devine, D. P., & Watson, S. J. (1997) · Seminars in Neuroscience · doi:10.1006/smns.1997.0108 · Cited by 48
Self-citation
Induction of conditioned place preference and dopamine release by salsolinol in posterior VTA of rats: Involvement of μ-opioid receptors
Hipólito, L., Martí‐Prats, L., Sánchez-Catalán, M. J., Polache, A., & Granero, L. M. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.04.014 · Cited by 47
Suppression of c‐fos induction in the nucleus accumbens prevents acquisition but not expression of morphine‐conditioned place preference
Tolliver, B. K., Sganga, M. W., & Sharp, F. R. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00214.x · Cited by 48
Opposite environmental regulation of heroin and amphetamine self-administration in the rat
Caprioli, D., Celentano, M., Paolone, G., Lucantonio, F., Bari, A., Nencini, P., & Badiani, A. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1154-3 · Cited by 45
Could a common biochemical mechanism underlie addictions?
Betz, C., Mihalic, D., Pinto, M. E., & Raffa, R. B. (2000) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1046/j.1365-2710.2000.00260.x · Cited by 44
Dissociable effects of the κ-opioid receptor agonists bremazocine, U69593, and U50488H on locomotor activity and long-term behavioral sensitization induced by amphetamine and cocaine
Vanderschuren, L. J. M. J., Schoffelmeer, A. N. M., Wardeh, G., & Vries, T. J. D. (2000) · Psychopharmacology · doi:10.1007/s002130000424 · Cited by 43
Modulation of morphine-induced Fos-immunoreactivity by the cannabinoid receptor antagonist SR 141716
Singh, M. E., Verty, A. N. A., Price, I., McGregor, I. S., & Mallet, P. E. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.08.008 · Cited by 45
Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice
Elmer, G. I., Pieper, J. O., Levy, J., Rubinstein, M., Low, M. J., Grandy, D. K., & Wise, R. A. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0051-2 · Cited by 44
Self-citation
Endogenous Opioids in Dopaminergic Cell Body Regions Modulate Amphetamine-Induced Increases in Extracellular Dopamine Levels in the Terminal Regions
Schad, C. A., Justice, J. B., & Holtzman, S. G. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.300.3.932 · Cited by 43
Effects of naltrexone on cocaine- and sucrose-seeking behaviour in response to associated stimuli in rats
Burattini, C., Burbassi, S., Aicardi, G., & Cervo, L. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707007705 · Cited by 43
Dopaminergic mediation of the discriminative stimulus effects of bupropion in rats
Terry, P., & Katz, J. L. (1997) · Psychopharmacology · doi:10.1007/s002130050443 · Cited by 43
κ-Opioid receptor blockade with nor-binaltorphimine modulates cocaine self-administration in drug-naive rats
Kuzmin, A. V., Gerrits, M. A. F. M., & van Ree, J. M. (1998) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00637-2 · Cited by 43
Acute and repeated activation of male sexual behavior by tail pinch: Opioid and dopaminergic mechanisms
Lepton, M., & Stewart, J. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(95)02270-8 · Cited by 43
Modulatory Effect of Environmental Context and Drug History on Heroin-Induced Psychomotor Activity and Fos Protein Expression in the Rat Brain
Paolone, G., Conversi, D., Caprioli, D., Bianco, P. D., Nencini, P., Cabib, S., & Badiani, A. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301388 · Cited by 42
Differential role of δ-opioid receptors in the development and expression of behavioral sensitization to cocaine
Heidbreder, C. A., Shoaib, M. C., & Shippenberg, T. S. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(95)00815-2 · Cited by 42
Effect of Chronic Ethanol on Enkephalin in the Hypothalamus and Extra‐Hypothalamic Areas
Chang, G., Barson, J. R., Karatayev, O., Chang, S. Y. A., Chen, Y., & LEIBOWITZ, S. F. (2010) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01148.x · Cited by 44
Evaluation of opioid receptor subtype antagonist effects in the ventral tegmental area upon food intake under deprivation, glucoprivic and palatable conditions
Ragnauth, A. K., Ruegg, H., & Bodnar, R. J. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00539-8 · Cited by 42
Modulation of cellular activity and synaptic transmission in the ventral tegmental area
Mathon, D. S., Kamal, A., Smidt, M. P., & Ramakers, G. M. J. (2003) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2003.08.097 · Cited by 41
Naltrexone affects cocaine self-administration in naıve rats through the ventral tegmental area rather than dopaminergic target regions
Ramsey, N. F., Gerrits, M. A. F. M., & van Ree, J. M. (1999) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(98)00009-1 · Cited by 41
Development of sensitization to methamphetamine in offspring prenatally exposed to morphine, methadone and buprenorphine
Chiang, Y., Hung, T., & Ho, I. (2013) · Addiction Biology · doi:10.1111/adb.12055 · Cited by 40
Pseudoginsenoside-F11 inhibits methamphetamine-induced behaviors by regulating dopaminergic and GABAergic neurons in the nucleus accumbens
Fu, K., Lin, H., Miyamoto, Y., Wu, C., Yang, J., Uno, K., & Nitta, A. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4159-8 · Cited by 40
Opioid receptor modulation of feeding-evoked dopamine release in the rat nucleus accumbens
Taber, M. T., Zernig, G., & Fibiger, H. C. (1998) · Brain Research · doi:10.1016/s0006-8993(97)01124-4 · Cited by 41
Drug context differently regulates cocaine versus heroin self-administration and cocaine- versus heroin-induced Fos mRNA expression in the rat
Celentano, M., Caprioli, D., Dipasquale, P., Cardillo, V., Nencini, P., Gaetani, S., & Badiani, A. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1467-x · Cited by 40
Alterations of prodynorphin gene expression in the rat mesocorticolimbic system during heroin self-administration
Solecki, W., Ziolkowska, B., Krowka, T., Gieryk, A., Filip, M., & Przewlocki, R. (2009) · Brain Research · doi:10.1016/j.brainres.2008.12.002 · Cited by 39
Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor
Margolis, E. B., Fujita, W., Devi, L. A., & Fields, H. L. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.06.019 · Cited by 39
The effects of early life stress on motivated behaviors: A role for gonadal hormones
Eck, S. R., & Bangasser, D. A. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.014 · Cited by 40
Chapter 5 Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine
Baumann, M. H., Pablo, J. P., Ali, S. F., Rothman, R. B., & Mash, D. C. (2001) · The Alkaloids. Chemistry and biology/The alkaloids. Chemistry and biology · doi:10.1016/s0099-9598(01)56009-5 · Cited by 39
Haloperidol Disrupts Opioid-Antinociceptive Tolerance and Physical Dependence
Yang, C., Chen, Y., Tang, L., & Wang, Z. J. (2011) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.110.175539 · Cited by 38
Effects of the Kappa-opioid Receptor Agonist, U69593, on the Development of Sensitization and on the Maintenance of Cocaine Self-administration
Schenk, S. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00190-1 · Cited by 38
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms
Rüedi‐Bettschen, D., Rowlett, J. K., Spealman, R. D., & Platt, D. M. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1705-2 · Cited by 37
Methamphetamine-induced behavioral sensitization in mice: alterations in μ-opioid receptor
Chiu, C., Ma, T., & Ho, I. K. (2006) · Journal of Biomedical Science · doi:10.1007/s11373-006-9102-x · Cited by 37
Effects of naltrexone on amphetamine-induced locomotion and rearing: acute and repeated injections
Balcells‐Oliveró, M., & Vezina, P. (1997) · Psychopharmacology · doi:10.1007/s002130050288 · Cited by 37
Expression of Amphetamine-Induced Behavioral Sensitization after Short- and Long-Term Withdrawal Periods: Participation of μ- and δ-Opioid Receptors
Magendzo, K., & Bustos, G. A. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300063 · Cited by 37
Ventral tegmental injections of morphine but not U-50,488H enhance feeding in food-deprived rats
Noel, M. B., & Wise, R. A. (1993) · Brain Research · doi:10.1016/0006-8993(93)91139-j · Cited by 37
Self-citation
Genetic and pharmacological manipulation of μ opioid receptors in mice reveals a differential effect on behavioral sensitization to cocaine
Hummel, M., Ansonoff, M. A., Pintar, J. E., & Unterwald, E. M. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.01.025 · Cited by 36
Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors
Soderman, A. R., & Unterwald, E. M. (2009) · Brain Research · doi:10.1016/j.brainres.2009.08.035 · Cited by 36
The delta opioid receptor antagonist, SoRI‐9409, decreases yohimbine stress‐induced reinstatement of ethanol‐seeking
Nielsen, C. K., Simms, J. A., Bito‐Onon, J. J., Li, R., Ananthan, S., & Bartlett, S. E. (2011) · Addiction Biology · doi:10.1111/j.1369-1600.2010.00295.x · Cited by 36
The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research
Banks, M. L. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_268 · Cited by 36
Microinjection of the δ-opioid receptor selective antagonist naltrindole 5′-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement
WARD, S., & Roberts, D. C. S. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.05.003 · Cited by 34
Salt Appetite in Sodium-Depleted or Sodium-Replete Conditions: Possible Role of Opioid Receptors
Lucas, L., Grillo, C. A., & McEwen, B. S. (2007) · Neuroendocrinology · doi:10.1159/000102536 · Cited by 33
Ultrastructural localization of enkephalin and μ-opioid receptors in the rat ventral tegmental area
Garzón, M., & Pickel, V. M. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00249-x · Cited by 33
In vivo analysis of the role of dopamine in stimulant and opiate self-administration.
Gratton, A. P. (1996) · PubMed · Cited by 34
Acute δ-opioid receptor activation induces CREB phosphorylation in NG108-15 cells
Bilecki, W., Höllt, V., & Przewłocki, R. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00018-2 · Cited by 32
Effects of dextromethorphan on dopamine release in the nucleus accumbens: Interactions with morphine
Steinmiller, C. L. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)01080-8 · Cited by 33
Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors
Escobar, A. P., Casanova, J. P., Andrés, M. E., & Fuentealba, J. A. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00057 · Cited by 32
Blockade of stimulant-induced preprodynorphin mRNA expression in the striatal matrix by serotonin depletion
Horner, K. A., Adams, D. H., Hanson, G. R., & Keefe, K. A. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.10.030 · Cited by 31
Involvement of cholinergic neurons in the release of dopamine elicited by stimulation of μ-opioid receptors in striatum
Dourmap, N., Cléro, É., & Costentin, J. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01319-4 · Cited by 31
Effects of the Mixed Mu/Kappa Opioid Nalbuphine on Cocaine-Induced Changes in Subjective and Cardiovascular Responses in Men
Mello, N. K., Mendelson, J. H., Sholar, M. B., Jaszyna-Gasior, M., Goletiani, N. V., & Siegel, A. J. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300631 · Cited by 31
Prior morphine exposure enhances ibogaine antagonism of morphine-induced locomotor stimulation
Pearl, S. M., Glick, S. D., & Johnson, D. W. (1995) · Psychopharmacology · doi:10.1007/bf02246495 · Cited by 31
Key differences in regulation of opioid receptors localized to presynaptic terminals compared to somas: Relevance for novel therapeutics
Coutens, B., & Ingram, S. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109408 · Cited by 30
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens
Peana, A. T., Muggironi, G., Fois, G. R., Zinellu, M., Vinci, S., & Acquas, E. (2011) · Alcohol · doi:10.1016/j.alcohol.2011.06.003 · Cited by 30
Changes in ensemble activity of hippocampus CA1 neurons induced by chronic morphine administration in freely behaving mice
Liu, F., Jiang, H., Zhong, W., Wu, X., & Luo, J. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.052 · Cited by 30
Naltrexone in the Treatment of Alcohol Dependence
Unterwald, E. M. (2008) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e318182b20f · Cited by 30
Effects of Repeated Nicotine Administration and Footshock Stress on Rat Mesoprefrontal Dopamine Systems Evidence for Opioid Mechanisms
George, T. P. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00165-7 · Cited by 30
Effects of diabetes on spontaneous locomotor activity in mice
Kamei, J., Saitoh, A., Iwamoto, Y., Funada, M., Suzuki, T., Misawa, M., Nagase, H., & Kasuya, Y. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90292-5 · Cited by 29

Authors: Devine, D. P., Leone, P., Pocock, D., & Wise, R. A.
Affiliations: Concordia University (CA)
ORCID: Devine, D P
Leone, P
Wise, R A
Venue: The Journal of Pharmacology and Experimental Therapeutics
Publisher: Elsevier BV
Published: 1993-07
Volume: 266
Issue: 3
Pages: 1236-1246
ISSN: 0022-3565 (ISSN-L)
DOI: 10.1016/s0022-3565(25)39324-9
OpenAlex: W2108098398
Cited by: 382
References: 0
Citations by year: 2026: 7 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 9 · 2020: 8 · 2019: 10 · 2018: 5 · 2017: 10 · 2016: 7 · 2015: 10 · 2014: 7 · 2013: 13 · 2012: 10
FWCI: 3.37
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Pharmacology and Experimental Therapeutics (publishedVersion)
PubMed (publishedVersion)
PubMed
Funders: National Institute on Drug Abuse (DA1720)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: ventral tegmental area, mu-opioid receptor, delta opioid receptor, kappa opioid receptor, dopamine release, ventral striatum, dopamine metabolites, DAMGO, DPDPE, U50,488H, naltrindole, CTOP, mesolimbic dopamine system, opioid receptor selectivity, enkephalin, opioid agonists, opioid antagonists
MeSH terms: Amino Acid Sequence, Analgesics, Animals, Chromatography, High Pressure Liquid, Corpus Striatum, Dialysis, Dopamine, Enkephalins, Homovanillic Acid, Hydroxyindoleacetic Acid, Limbic System, Male, Microinjections, Molecular Sequence Data, Naltrexone, Narcotic Antagonists, Pyrrolidines, Rats, Inbred Strains, Receptors, Opioid, Tegmentum Mesencephali, 3,4-Dihydroxyphenylacetic Acid, 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer, Enkephalin, Ala(2)-MePhe(4)-Gly(5)-, Enkephalin, D-Penicillamine (2,5)-, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks