The DOI matches its Crossref record; 170 of the 170 references it cites were found in a registry or an index.
Going to the heart of the matter
Abstract
Objective Negative emotions, such as anger, anxiety, and depression, have emerged as potentially important risk factors for coronary heart disease. The purpose of this article is to consider the nature and function of emotions, to review epidemiological evidence for an association between the three negative emotions and coronary heart disease (CHD), to discuss briefly the mechanisms by which emotions may be linked to CHD, and to consider this evidence in light of theoretical insights provided by mainstream psychological research on emotions.Methods We collected articles published between 1980 and 1998 on the relationship between each negative emotion and CHD. We also collected review articles or chapters published during the same time period that considered mechanisms by which emotions may increase CHD risk. We used a qualitative approach to review the published literature.Results Evidence that anxiety is involved in the onset of CHD is strongest, whereas evidence for an association between anger and CHD is limited but suggestive. Although depression has consistently been linked to mortality following a myocardial infarction, evidence for its role in the onset of coronary disease is quite mixed. Numerous unresolved issues leave our current understanding of the emotion-health relationship incomplete. Psychological theories of emotion are considered to help address gaps in our knowledge.Conclusion Growing evidence indicates that negative emotions may influence the development of CHD. The focused and specific consideration of negative emotions and their possible role in the etiology of CHD gives insight into current knowledge and suggests important directions for future research.
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In the citing paper
“and anxiety can be involved in the onset of CHD [3].”
In the citing paper
“Psychosocial stress, including chronic anxiety, is a major risk factor for somatic disease, including cardiovascular disease”
From Exposed to events that never happen: generalized unsafety, the default stress response, and prolonged autonomic activity (2017) · cites this paper as Kubzansky and Kawachi, 2000
Citations
Cites
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Research works printed but not linked: 3
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Cited by
Sorted by citations
The benefits of frequent positive affect: Does happiness lead to success?
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Havranek, E. P., Mujahid, M. S., Barr, D. A., Blair, I. V., Cohen, M. S., Cruz-Flores, S., Davey-Smith, G., Dennison-Himmelfarb, C. R., Lauer, M. S., Lockwood, D. W., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000228 · Cited by 1,472
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Metadata
- Authors
- Kubzansky, L. D., & Kawachi, I.
- Affiliations
- Harvard University (US)
- Corresponding author
- Kubzansky, Laura D
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2000-04
- Volume
- 48
- Issue
- 4-5
- Pages
- 323-337
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2144555034
- Cited by
- 442
- References
- 168
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 8 · 2023: 8 · 2022: 15 · 2021: 16 · 2020: 15 · 2019: 16 · 2018: 13 · 2017: 13 · 2016: 19 · 2015: 27 · 2014: 23 · 2013: 16 · 2012: 23
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- negative emotions, coronary artery disease, anger, anxiety, depression, emotions and health, myocardial infarction mortality, psychosocial risk factors
- MeSH terms
- Affect, Anger, Anxiety, Coronary Disease, Depressive Disorder, Female, Humans, Male, Risk Factors, Epidemiologic Studies
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