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Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.

De Lean, A, Hancock, A A, Lefkowitz, R J·1982·Molecular Pharmacology

Abstract

ANDRE DE LEAN, ARTHUR A. HANCOCK, AND ROBERT J. LEFKOWITZ. Validation and Statistical Analysis of a Computer Modeling Method for Quantitative Analysis of Radioligand Binding Data for Mixtures of Pharmacological Receptor Subtypes . . 5 DEBORAH J. KAHN, JOAN C. MITRIUS, AND DAVID C. U’PRICHARD. Alpha2-Adrenergic Receptors in Neuroblastoma x Glioma Hybrid Cells: Characterization with Agonist and Antagonist Radioligands and Relationship to Adenylate Cyclase 17 DAVID B. BYLUND, J. RICARDO MARTINEZ, AND DAN L. PIERCE. Regulation of Autonomic Receptors in Rat Submandibular Gland . . . 27 JOEL S. KARLINER, HARVEY J. MOTULSKY, AND PAUL A. INSEL. Apparent “Down-Regulation” of Human Platelet Alpha2-Adrenergic Receptors Is Due to Retained Agonist 36 MARK W. HAMBLIN AND IAN CREESE. Phenoxybenzamine Treatment Differentiates Dopaminergic 3H-Ligand Binding Sites in Bovine Caudate Membranes . 44 MARK W. HAMBLIN AND IAN CREESE. Heat Treatment Mimics Guanosine 5’-Triphosphate Effects on Dopaminergic 3H-Ligand Binding to Bovine Caudate Membranes 52 TED H. CHIu, DAVID M. DRYDEN, AND HOWARD C. ROSENBERG. Kinetics of [3H]Flunitrazepam Binding to Membrane-Bound Benzodiazepine Receptors 57

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Metadata

Authors
De Lean, A., Hancock, A. A., & Lefkowitz, R. J.
Venue
Molecular Pharmacology
Publisher
Elsevier BV
Published
1982-01
Volume
21
Issue
1
Pages
5-16
ISSN
0026-895X (ISSN-L)
OpenAlex
W2336762688
Cited by
591
References
0
FWCI
15.06
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. https://app.cochat.ai/papers/10.1016/s0026-895x(25)14584-7
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De Lean, A., Hancock, A. A., & Lefkowitz, R. J. (1982). Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. Molecular Pharmacology. https://doi.org/10.1016/s0026-895x(25)14584-7

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