3-Deoxy-1β,20-dihydroxyecdysone from the leaves of Diploclisia glaucescens
Abstract
Chemical investigation of methanol extract of the leaves of Diploclisia glaucescens of the family Menispermaceae furnished a new ecdysteroid, 3-deoxy-1beta,20-dihydroxyecdysone. The structure of the new ecdysteroid was established on detailed analysis of spectral data. The 3-deoxy ecdysteroid showed 40% potency of 20-hydroxyecdysone in the spiracle index assay using the fourth instar larvae of the silkworm Bombyx mori.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Ecdysteroids are the major components of D. glaucescens.
“Phytochemical investigations revealed that ecdysteroidsare the major components of D. glaucescens [2,3,4].”
Cites
Glossary of Indian Medicinal Plants
Chopra, R. N., Nayar, S. L., & Chopra, I. (1956) · Cited by 5,197 · see citing works
Hoffmann, J. (1980) · Elsevier eBooks · Cited by 629 · see citing works
An extensive ecdysteroid CoMFA
Dinan, L. N., Hormann, R. E., & Fujimoto, T. T. (1999) · Journal of Computer-Aided Molecular Design · doi:10.1023/a:1008052320014 · Cited by 137 · see citing works
Ecdysterone from stem of Diploclisia glaucescens
Bandara, B. M. R., Jayasinghe, L., Karunaratne, V., Wannigama, G. P., Bokel, M., Kraus, W., & Sotheeswaran, S. (1989) · Phytochemistry · doi:10.1016/0031-9422(89)80185-2 · Cited by 73 · see citing works
Vokáč, K., Buděšńský, M., Harmatha, J., & Kohoutová, J. (1998) · Phytochemistry · doi:10.1016/s0031-9422(98)00448-8 · Cited by 63 · see citing works
Diploclisin, a bidesmosidic triterpenoid saponin from Diploclisia glaucescens
Bandara, B. M. R., Jayasinghe, L., Karunaratne, V., Wannigama, G. P., Kraus, W. H., Bokel, M., & Sotheeswaran, S. (1989) · Phytochemistry · doi:10.1016/s0031-9422(00)98088-9 · Cited by 19 · see citing works
Self-citationSaponins ofDiploclisia glaucescens
Jayasinghe, U. L. B., Wannigama, G. P., & MacLeod, J. K. (1993) · Natural product letters · doi:10.1080/10575639308043818 · Cited by 13 · see citing works
Triterpenoidal Constituents ofDiploclisia glaucescens
Bandara, B. M. R., Jayasinghe, U. L. B., Karunaratne, V., et al. (1990) · Planta Medica · doi:10.1055/s-2006-960960 · Cited by 10 · see citing works
Glucuronides of Diploclisia glaucescens
Jayasinghe, U. L. B., Wannigama, G. P., & MacLeod, J. K. (1998) · Cited by 5 · see citing works
BENZYLISOQUINOLINE ALKALOIDS FROM ANAMIRTA COCCULUS AND DIPLOCLISIA GLAUCESCENS
JAYASINGHE, U., Wannigama, G. P., Balasubramaniam, S., et al. (1992) · Journal of the National Science Foundation of Sri Lanka · doi:10.4038/jnsfsr.v20i2.8073 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The Phytochemical, Biological, and Medicinal Attributes of Phytoecdysteroids: An Updated Review
Das, N., Mishra, S. K., Bishayee, A., Ali, E. S., & Bishayee, A. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2020.10.012 · Cited by 115 · see citing works
A pyridine ring-containing ecdysteroid from Diploclisia glaucescens
Jayasinghe, L., Jayasooriya, C. P., Hara, N., & Fujimoto, Y. (2003) · Tetrahedron Letters · doi:10.1016/j.tetlet.2003.09.177 · Cited by 58 · see citing works
Self-citationFang, L., Li, J., Zhou, J., Wang, X., & Guo, L. (2017) · Molecules · doi:10.3390/molecules22081310 · Cited by 20 · see citing works
A new ecdysteroid, 2-deoxy-5β,20-dihydroxyecdysone from the fruits of Diploclisia glaucescens
Jayasinghe, L., Mallika Kumarihamy, B. M., Suranga Arundathie, B. G., Dissanayake, L., Hara, N., & Fujimoto, Y. (2003) · Steroids · doi:10.1016/s0039-128x(03)00046-1 · Cited by 22 · see citing works
- Authors
- Jayasinghe, L., Jayasooriya, C. P., Oyama, K., & Fujimoto, Y.
- Affiliations
- National Institute of Fundamental Studies (LK)
- Tokyo Institute of Technology (JP)
- Corresponding author
- Jayasinghe, Lalith
- Venue
- Steroids
- Publisher
- Elsevier BV
- Published
- 2002-06
- Volume
- 67
- Issue
- 7
- Pages
- 555-558
- ISSN
- 0039-128X (ISSN-L)
- OpenAlex
- W2066415537
- Cited by
- 14
- References
- 10
- Citations by year
- 2026: 2 · 2022: 1 · 2020: 1 · 2018: 1 · 2017: 1 · 2012: 2
- FWCI
- 0.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Steroids (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical Studies and Bioactivities
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- ecdysteroids, Menispermaceae, natural product isolation, structure elucidation, 20-hydroxyecdysone, Bombyx mori, insect growth regulators, leaf extract
- MeSH terms
- Ecdysone, Ecdysterone, Molecular Structure, Plant Leaves, Menispermaceae
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
