Transgenic mouse models for studying mutations in vivo: applications in aging research

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Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age

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Adeno‐associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo†‡

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What keeps cells in tissues behaving normally in the face of myriad mutations?

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Making ends meet in old age: DSB repair and aging

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Mitochondrial Apoptosis Reduces Mutagenesis Regardless Oxidative Stress

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Novel strategies to improve viral gene targeting and therapeutic liver repopulation in vivo

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Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age

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Evaluation of a plasmid-based transgenic mouse model for detecting in vivo mutations

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Rapid accumulation of genome rearrangements in liver but not in brain of old mice

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Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in newborn and old lacZ-transgenic mouse

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