The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Highly Repeated Sequences in Mammalian Genomes
Open accessAbstract
Publisher Summary This chapter discusses the structure and organization of mammalian, highly repeated sequences at the molecular level. There is a description of tandemly repeated sequences, that are, satellites, and the segments that are interspersed among other genomic DNA sequences. The methods for the analysis of repeated DNA sequences are measurement of DNA renaturation kinetics and isopycnic centrifugation in gradients of CsCl and CsSO4. Eukaryote genomes can be divided into classes of DNA sequences according to the reiteration frequency. Many highly repeated sequences are in long tandem arrays. Some repetitive sequences are dispersed throughout major portions of genomes amid either other repeated sequences or sequences present only once per genome, that are, uniquesequences. The characteristic organizational feature of satellites and cryptic satellites is the tandem repetition of a unit DNA sequence. Satellite arrays resist separation by isopycnic centrifugation and instead remain within the main density fraction of genomic DNA. The repeat unit and its tandem organization can be revealed by restriction endonuclease digestion.
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Citations
Cites
Gene conversion: some implications for immunoglobulin genes
Baltimore, D. (1981) · Cell · doi:10.1016/0092-8674(81)90082-9 · Cited by 486
Singer, D. S. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50624-4 · Cited by 57
Cited by
A highly conserved repetitive DNA sequence,(TTAGGG) n, present at the telomeres of human chromosomes
Moyzis, R. K., Buckingham, J. M., Cram, L. S., Dani, M., Deaven, L. L., Jones, M. D., Meyne, J., Ratliff, R. L., & Wu, J. R. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.18.6622 · Cited by 1,820
Replication Timing of Genes and Middle Repetitive Sequences
Goldman, M. A., Holmquist, G. P., Gray, M. C., Caston, L. A., & Nag, A. (1984) · Science · doi:10.1126/science.6719109 · Cited by 538
Hierarchical order in chromosome-specific human alpha satellite DNA
Willard, H. F., & Waye, J. S. (1987) · Trends in Genetics · doi:10.1016/0168-9525(87)90232-0 · Cited by 494
Molineaux, S. M., Engh, H., de Ferra, F., Hudson, L., & Lazzarini, R. A. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.19.7542 · Cited by 141
Makałowski, W., Gotea, V., Pande, A., & Makałowska, I. (2019) · Methods in Molecular Biology · doi:10.1007/978-1-4939-9074-0_6 · Cited by 127
Metadata
- Authors
- Singer, M. F.
- Venue
- International Review of Cytology
- Publisher
- Elsevier
- Published
- 1982
- Volume
- 76
- Pages
- 67-112
- ISSN
- 0074-7696 (ISSN-L)
- OpenAlex
- W2160064257
- Cited by
- 647
- References
- 2
- FWCI
- 72.12
- Type
- book chapter
- Language
- en
- Open access
- green
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- Singer, M. F. (1982). Highly Repeated Sequences in Mammalian Genomes. International Review of Cytology. https://doi.org/10.1016/s0074-7696(08)61789-1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
