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Cited by 175

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Antagonistic Signaling by Caronte , a Novel Cerberus -Related Gene, Establishes Left–Right Asymmetric Gene Expression

Open access
Yokouchi, Yuji, Vogan, Kyle J, Pearse, Richard V, Tabin, Clifford J·1999·Cell

Abstract

Left-right asymmetry is initiated during chick embryogenesis in small domains near Hensen's node. Subsequently, broad asymmetric gene expression domains are established in the lateral plate mesoderm, ultimately determining the directionality of morphogenetic events. The transfer of asymmetric information from the node to the lateral plate is mediated by Caronte (Car), a novel member of the Cerberus/Dan gene family, which induces targets by antagonizing symmetrically expressed BMP signals. In addition, BMP antagonism by Car induces asymmetric expression of Lefty in the midline, preventing spread of left-sided signals to the contralateral side.

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Crossref · 10.1016/s0092-8674(00)80045-8

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Metadata

Authors
Yokouchi, Y., Vogan, K. J., Pearse, R. V., & Tabin, C. J.
Venue
Cell
Publisher
Elsevier BV
Published
1999-09
Volume
98
Issue
5
Pages
573-583
ISSN
0092-8674 (ISSN-L)
OpenAlex
W2073119991
Cited by
175
References
1
FWCI
8.70
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Antagonistic Signaling by Caronte , a Novel Cerberus -Related Gene, Establishes Left–Right Asymmetric Gene Expression. https://app.cochat.ai/papers/10.1016/s0092-8674(00)80045-8
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Yokouchi, Y., Vogan, K. J., Pearse, R. V., & Tabin, C. J. (1999). Antagonistic Signaling by Caronte , a Novel Cerberus -Related Gene, Establishes Left–Right Asymmetric Gene Expression. Cell. https://doi.org/10.1016/s0092-8674(00)80045-8

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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