NF-κB Activation: The IκB Kinase Revealed?

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., & Karin, M. (1997) · Nature · doi:10.1038/41493 · Cited by 2,125

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

Liu, Z.-G., Hsu, H., Goeddel, D. V., & Karin, M. (1996) · Cell · doi:10.1016/s0092-8674(00)81375-6 · Cited by 1,937

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

Lee, H., Herrmann, A., Deng, J.-H., Kujawski, M., Niu, G., Li, Z., Forman, S., Jove, R., Pardoll, D. M., & Yu, H. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.02.015 · Cited by 683

Transcriptional Cross Talk between NF-κB and p53

Webster, G. A., & Perkins, N. D. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3485 · Cited by 598

Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways

Vercammen, D., Brouckaert, G., Denecker, G., Van de Craen, M., Declercq, W., Fiers, W., & Vandenabeele, P. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.5.919 · Cited by 556

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

Yang, S.-R., Wright, J., Bauter, M., Seweryniak, K., Kode, A., & Rahman, I. (2007) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00308.2006 · Cited by 391

Nedd8 Modification of Cul-1 Activates SCFβTrCP-Dependent Ubiquitination of IκBα

Read, M. A., Brownell, J. E., Gladysheva, T. B., Hottelet, M., Parent, L. A., Coggins, M. B., Pierce, J. W., Podust, V. N., Luo, R.-S., Chau, V., et al. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.7.2326-2333.2000 · Cited by 363

Induction of Apoptosis by Double-Stranded-RNA-Dependent Protein Kinase (PKR) Involves the α Subunit of Eukaryotic Translation Initiation Factor 2 and NF-κB

Gil, J., Alcamí, J., & Esteban, M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.7.4653 · Cited by 199

Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-κB site

Azimi, N., Brown, K., Bamford, R. N., Tagaya, Y., Siebenlist, U., & Waldmann, T. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2452 · Cited by 181

Distinct roles for the NF-κB1 (p50) and c-Rel transcription factors in inflammatory arthritis

Campbell, I. K., Gerondakis, S., O’Donnell, K., & Wicks, I. P. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8298 · Cited by 168

Oxidation of IκBα at Methionine 45 Is One Cause of Taurine Chloramine-induced Inhibition of NF-κB Activation

Kanayama, A., Inoue, J.-I., Sugita-Konishi, Y., Shimizu, M., & Miyamoto, Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110832200 · Cited by 147

Probiotic mixture VSL# 3: An overview of basic and clinical studies in chronic diseases

Cheng, F.-S., Pan, D., Chang, B., Jiang, M., & Sang, L.-X. (2020) · World Journal of Clinical Cases · doi:10.12998/wjcc.v8.i8.1361 · Cited by 147

Epstein–Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-κB through a pathway that includes the NF-κB-inducing kinase and the IκB kinases IKKα and IKKβ

Sylla, B. S., Hung, S. C., Davidson, D. M., Hatzivassiliou, E., Malinin, N. L., Wallach, D., Gilmore, T. D., Kieff, E., & Mosialos, G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.17.10106 · Cited by 137

DNA damage drives accelerated bone aging via an NF- κ B–dependent mechanism

Chen, Q., Liu, K., Robinson, A. R., Clauson, C. L., Blair, H. C., Robbins, P. D., Niedernhofer, L. J., & Ouyang, H. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1851 · Cited by 135

Zinc activates NF-κB in HUT-78 cells

Prasad, A. S., Bao, B., Beck, F. W. J., & Sarkar, F. H. (2001) · Journal of Laboratory and Clinical Medicine · doi:10.1067/mlc.2001.118108 · Cited by 94

Molecular modeling of the oxidized form of nuclear factor-κB suggests a mechanism for redox regulation of DNA binding and transcriptional activation

Chandrasekaran, V., & Taylor, E. W. (2008) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2007.05.007 · Cited by 11

Inflammatory cytokines enhance muscarinic-mediated arachidonic acid release through p38 mitogen-activated protein kinase in A2058 cells

Wood, M. W., Segal, J. A., Mark, R. J., Ogden, A. M., & Felder, C. C. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0742033.x · Cited by 11