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Endocytosis and Signaling
Open accessAbstract
Far from being a simple attenuator, endocytosis is now also implicated in the initiation and propagation of signals. Signaling reciprocates by controlling endocytosis and contributing to its ability to selectively sort receptors. It appears that the quiet days of endocytosis as a relatively “stand-alone” process are over, as we expose the intricate network that connects it to actin, membrane dynamics, lipids metabolism, signaling adaptors, and transducers. Phenotypically, this is mirrored by an important role of endocytosis in proliferation, differentiation, cell survival, neurotransmission, embryogenesis, and cell fate specification. An emerging role of alterations of the endocytic machinery in diseases is therefore predicted.
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Citations
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Sigismund, S., Confalonieri, S., Ciliberto, A., Polo, S., Scita, G., & Di Fiore, P. P. (2012) · Physiological Reviews · doi:10.1152/physrev.00005.2011 · Cited by 338
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Lu, Q., Hope, L. W., Brasch, M., Reinhard, C., & Cohen, S. N. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0932599100 · Cited by 301
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Mishra, S. K., Agostinelli, N. R., Brett, T. J., Mizukami, I., Ross, T. S., & Traub, L. M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m108177200 · Cited by 111
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Metadata
- Authors
- Di Fiore, P. P., & De Camilli, P.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2001-07
- Volume
- 106
- Issue
- 1
- Pages
- 1-4
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2014263971
- Cited by
- 378
- References
- 0
- FWCI
- 12.28
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
