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Cited by 531Diabetes Management and EducationDiabetes Treatment and ManagementDiabetes Management and Research

The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.

Systematic review and meta-analysis of randomised controlled trials of psychological interventions to improve glycaemic control in patients with type 2 diabetes

Ismail, Khalida, Winkley, Kirsty, Rabe-Hesketh, Sophia·2004·The Lancet
DOI 10.1016/s0140-6736(04)16202-8
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Abstract

Background Adherence difficulties and psychological problems are associated with poor glycaemic control in diabetes. We undertook a systematic review and meta-analysis of psychological therapies to assess their effectiveness in improving glycaemic control in type 2 diabetes.Methods We searched MEDLINE, PsychINFO, EMBASE, and the Cochrane Central Register of Controlled Trials up to January, 2003. Eligible studies were randomised controlled trials that involved people with type 2 diabetes and evaluated a psychological therapy (counselling, cognitive behaviour therapy, or psychodynamic therapy) to improve diabetes control. We extracted the number of participants, their age, duration of diabetes, glycaemic control, type of psychological therapy, its mode of delivery, and type of intervention in the control group. The main outcome was long-term glycaemic control measured by percentage of glycated haemoglobin. Blood glucose concentration, weight, and psychological distress were also measured. Pooled standardised effect sizes were calculated.Findings 25 trials were eligible for the review. In 12 trials, the mean percentage glycated haemoglobin was lower in people assigned a psychological intervention than in the control group (usual care, education, waiting list, or attention control); the pooled mean difference was -0.32 (95% CI -0.57 to -0.07) equivalent to an absolute difference of -0.76%. There were non-significant differences in blood glucose concentration (eight trials; -0.11 [-0.65 to 0.42]) and weight gain (nine trials; 0.37 [-0.18 to 0.93]). Psychological distress was significantly lower in the intervention groups (five trials; -0.58 [-0.95 to -0.20]).Interpretation In type 2 diabetes, there are improvements in long-term glycaemic control and psychological distress but not in weight control or blood glucose concentration in people who receive psychological therapies.

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Research works printed but not linked: 5

  1. Meca, 1998, Meta-analysis de las intervenciones conductuales en el tratamiento de la diabetes en Espana, Rev Psicol Gral Aplic, 51, 501
  2. Ismail, 2001, Psychological interventions for improving glycaemic control in patients with diabetes mellitus (Cochrane Review)
  3. Bradburn, 1998, sbe24 Metan: an alternative meta-analysis command, Stata Technical Bulletin, 44, 4
  4. Rodriguez, 1987, Modificacion de conducta y mejora en el cumplimiento del tratamiento en diabeticos tipo II, Rev Esp Ter Comportamiento, 5, 233
  5. Zhu, 2001, The effect of biofeedback assisted relaxation training on cytokines in patients with type II diabetes, Chin J Clin Psychol, 9, 170

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Metadata

Authors
Ismail, K., Winkley, K., & Rabe-Hesketh, S.
Affiliations
King's College London (GB)
ORCID
Venue
The Lancet
Publisher
Elsevier BV
Published
2004-05
Volume
363
Issue
9421
Pages
1589-1597
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/s0140-6736(04)16202-8
OpenAlex
W2119408095
Cited by
531
References
62
Citations by year
2026: 9 · 2025: 7 · 2024: 12 · 2023: 10 · 2022: 15 · 2021: 23 · 2020: 20 · 2019: 24 · 2018: 34 · 2017: 31 · 2016: 30 · 2015: 28 · 2014: 31 · 2013: 40 · 2012: 27
FWCI
3.88
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • Research Portal (King's College London) (submittedVersion)
Funders
Psychiatry Research Trust
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
type 2 diabetes, psychological intervention, glycemic control, HbA1c, cognitive behavioral therapy, psychodynamic psychotherapy, counseling, psychological distress, weight gain, blood glucose, diabetes self-management
MeSH terms
Blood Glucose, Body Weight, Diabetes Mellitus, Type 2, Glycated Hemoglobin, Humans, Psychotherapy, Stress, Psychological, Randomized Controlled Trials as Topic

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