The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Renal dysfunction accompanying oral creatine supplements
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“With regard to the question of whether creatine has effect on renal function, a few case studies [249–252] reported that individuals purportedly taking creatine with or without other supplements presented with high creatinine levels and/or renal dysfunction [249–251].”
From International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine (2017) · cites this paper as [251]
In the citing paper
“Based on increased blood levels of creatinine and subsequent estimate of calculated creatinine clearance, his kidney health was presumed to be deteriorating, although he was otherwise in good health.”
From Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? (2021) · cites this paper as [51]
In the citing paper
“In 1998, a case study of a young male with focal segmental glomerulosclerosis and relapsing nephrotic syndrome was reported [51]. The young male, who had kidney disease for 8 years and was treated with cyclosporine (i.e., immunosuppressant) for 5 years, had recently begun ingesting creatine supplementation (15 g/day for 7 days; followed by 2 g/day for 7 weeks).”
From Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? (2021) · cites this paper as [51]
In the citing paper
“A few case study reports also appeared in the literature suggesting adverse events despite other mitigating factors unrelated to creatine supplementation [52–54] which subsequently have been debunked [15,55,56].”
From Safety of creatine supplementation: analysis of the prevalence of reported side effects in clinical trials and adverse event reports (2025) · cites this paper as [52]
Citations
Cites
Muscle creatine loading in men
Hultman, E., Soderlund, K., Timmons, J. A., Cederblad, G., & Greenhaff, P. L. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.1.232 · Cited by 822
Birch, R., Noble, D., & Greenhaff, P. L. (1994) · European Journal of Applied Physiology · doi:10.1007/bf01094800 · Cited by 251
Effect of Oral Creatine Supplementation on Jumping and Running Performance
Bosco, C., Tihanyi, J., Pucspk, J., Kovacs, I., Gabossy, A., COLLI, R., Pulvirenti, G., Tranquilli, C., Foti, C., Viru, M., et al. (1997) · International Journal of Sports Medicine · doi:10.1055/s-2007-972648 · Cited by 89
Creatine Supplementation and Exercise Performance
Maughan, R. J. (1995) · International Journal of Sport Nutrition · doi:10.1123/ijsn.5.2.94 · Cited by 82
Cited by
Sorted by citations
Creatine and Creatinine Metabolism
Wyss, M., & Kaddurah-Daouk, R. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.3.1107 · Cited by 2,950
Kreider, R. B., Kalman, D. S., Antonio, J., Ziegenfuss, T. N., Wildman, R., Collins, R., Candow, D. G., Kleiner, S. M., Almada, A. L., & Lopez, H. L. (2017) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-017-0173-z · Cited by 1,057
Physiological and Health Effects of Oral Creatine Supplementation
Terjung, R. L., Clarkson, P. M., Eichner, E. R., Greenhaff, P. L., Hespel, P., Israel, R. G., Kraemer, W. J., Meyer, R. A., Spriet, L. L., Tarnopolsky, M. A., et al. (2000) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200003000-00024 · Cited by 417
International Society of Sports Nutrition position stand: creatine supplementation and exercise
Buford, T. W., Kreider, R. B., Stout, J. R., Greenwood, M., Campbell, B., Spano, M., Ziegenfuss, T., Lopez, H., Landis, J., & Antonio, J. (2007) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-4-6 · Cited by 341
Clinical Pharmacology of the Dietary Supplement Creatine Monohydrate
Persky, A. M., & Brazeau, G. A. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01490-x · Cited by 333
Metadata
- Authors
- Pritchard, N., & Kalra, P.
- Affiliations
- Salford Royal NHS Foundation Trust (GB)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1998-04
- Volume
- 351
- Issue
- 9111
- Pages
- 1252-1253
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1973648573
- Cited by
- 213
- References
- 4
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 4 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 5 · 2019: 7 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 8 · 2014: 6 · 2013: 1 · 2012: 8
- FWCI
- 5.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Keywords
- creatine supplementation, renal dysfunction, creatine loading, serum creatinine, exercise performance, dietary supplements, drug safety
- MeSH terms
- Administration, Oral, Adult, Creatine, Glomerular Filtration Rate, Humans, Male, Nephrotic Syndrome, Dietary Supplements
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