The DOI matches its Crossref record; 257 of the 257 references it cites were found in a registry or an index.
Erectile dysfunction
Abstract
Erectile dysfunction is a common clinical entity that affects mainly men older than 40 years. In addition to the classical causes of erectile dysfunction, such as diabetes mellitus and hypertension, several common lifestyle factors, such as obesity, limited or an absence of physical exercise, and lower urinary tract symptoms, have been linked to the development of erectile dysfunction. Substantial steps have been taken in the study of the association between erectile dysfunction and cardiovascular disease. Erectile dysfunction is a strong predictor for coronary artery disease, and cardiovascular assessment of a non-cardiac patient presenting with erectile dysfunction is now recommended. Substantial advances have occurred in the understanding of the pathophysiology of erectile dysfunction that ultimately led to the development of successful oral therapies, namely the phosphodiesterase type 5 inhibitors. However, oral phosphodiesterase type 5 inhibitors have limitations, and present research is thus investigating cutting-edge therapeutic strategies including gene and cell-based technologies with the aim of discovering a cure for erectile dysfunction.
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“By now, there are several review papers and clinical guidelines available on ED,9, 10, 11, 12, 13 but the majority of these papers approach the assessment and treatment of ED from a purely medical perspective and pay only little attention to describing the psychosocial aspects of ED.”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [11]
In the citing paper
“The medical treatment of ED follows a stepwise program, moving from less invasive treatments such as lifestyle changes, pelvic floor exercises, and medication (changes) to more invasive modalities such as the use of mechanical devices, intracavernous injections, and surgical implantation of a penile prosthesis.9, 10, 11, 12”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [11]
In the citing paper
“Not only does shared decision-making increase patient autonomy, it also predicts a better course, adherence, and outcome of therapy because patients have more realistic treatment expectations.10, 11, 12”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [11]
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Metadata
- Authors
- Shamloul, R., & Ghanem, H.
- Affiliations
- University of Ottawa (CA)
- Cairo University (EG)
- Corresponding author
- Shamloul, Rany
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 381
- Issue
- 9861
- Pages
- 153-165
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W3108094084
- Cited by
- 1,091
- References
- 257
- Citations by year
- 2026: 69 · 2025: 104 · 2024: 125 · 2023: 117 · 2022: 95 · 2021: 105 · 2020: 94 · 2019: 78 · 2018: 71 · 2017: 56 · 2016: 58 · 2015: 42 · 2014: 53 · 2013: 22
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- The Lancet (publishedVersion)
- Colloquium Series on Integrated Systems Physiology From Molecule to Function (publishedVersion)
- PubMed (publishedVersion)
- Funders
- European Association of Urology
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Keywords
- erectile dysfunction, cardiovascular disease, coronary artery disease, phosphodiesterase-5 inhibitors, pathophysiology, lifestyle factors, obesity, diabetes mellitus, hypertension, lower urinary tract symptoms, physical activity, gene therapy, cell therapy
- MeSH terms
- Humans, Erectile Dysfunction, Male, Penis, Penile Prosthesis, Impotence, Vasculogenic, Phosphodiesterase 5 Inhibitors
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