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The burden of disease in older people and implications for health policy and practice

Prince, Martin J, Wu, Fan, Guo, Yanfei, Gutierrez Robledo, Luis M, O'Donnell, Martin, Sullivan, Richard, Yusuf, Salim·2015·The Lancet
DOI 10.1016/s0140-6736(14)61347-7
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Abstract

23% of the total global burden of disease is attributable to disorders in people aged 60 years and older. Although the proportion of the burden arising from older people (≥60 years) is highest in high-income regions, disability-adjusted life years (DALYs) per head are 40% higher in low-income and middle-income regions, accounted for by the increased burden per head of population arising from cardiovascular diseases, and sensory, respiratory, and infectious disorders. The leading contributors to disease burden in older people are cardiovascular diseases (30·3% of the total burden in people aged 60 years and older), malignant neoplasms (15·1%), chronic respiratory diseases (9·5%), musculoskeletal diseases (7·5%), and neurological and mental disorders (6·6%). A substantial and increased proportion of morbidity and mortality due to chronic disease occurs in older people. Primary prevention in adults aged younger than 60 years will improve health in successive cohorts of older people, but much of the potential to reduce disease burden will come from more effective primary, secondary, and tertiary prevention targeting older people. Obstacles include misplaced global health priorities, ageism, the poor preparedness of health systems to deliver age-appropriate care for chronic diseases, and the complexity of integrating care for complex multimorbidities. Although population ageing is driving the worldwide epidemic of chronic diseases, substantial untapped potential exists to modify t…

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Metadata

Authors
Prince, M. J., Wu, F., Guo, Y., Gutierrez Robledo, L. M., O'Donnell, M., Sullivan, R., & Yusuf, S.
Venue
The Lancet
Publisher
Elsevier BV
Published
2015-02
Volume
385
Issue
9967
Pages
549-562
ISSN
0140-6736
DOI
10.1016/s0140-6736(14)61347-7
Cited by
1,989
References
20
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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Prince, M. J., Wu, F., Guo, Y., Gutierrez Robledo, L. M., O'Donnell, M., Sullivan, R., & Yusuf, S. (2015). The burden of disease in older people and implications for health policy and practice. The Lancet. https://doi.org/10.1016/s0140-6736(14)61347-7