Idiopathic pulmonary fibrosis

Cancer Incidence in Five Continents

Doll, R., Muir, C. S., & Waterhouse, J. A. H. (1970) · Springer eBooks · doi:10.1007/978-3-642-85851-2 · Cited by 8,485

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

Raghu, G., Collard, H. R., Egan, J. J., Martinez, F. J., Behr, J., Brown, K. K., Colby, T. V., Cordier, J.-F., Flaherty, K. R., Lasky, J. A., et al. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2009-040gl · Cited by 7,186

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

Richeldi, L., du Bois, R. M., Raghu, G., Azuma, A., Brown, K. K., Costabel, U., Cottin, V., Flaherty, K. R., Hansell, D. M., Inoue, Y., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402584 · Cited by 4,654

An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias

Travis, W. D., Costabel, U., Hansell, D. M., King, T. E., Lynch, D. A., Nicholson, A. G., Ryerson, C. J., Ryu, J. H., Selman, M., Wells, A. U., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201308-1483st · Cited by 4,378

American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias

(2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.165.2.ats01 · Cited by 4,196

Fleischner Society: Glossary of Terms for Thoracic Imaging

Hansell, D. M., Bankier, A. A., MacMahon, H., McLoud, T. C., Müller, N. L., & Rémy, J. (2008) · Radiology · doi:10.1148/radiol.2462070712 · Cited by 4,189

A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

King, T. E., Bradford, W. Z., Castro-Bernardini, S., Fagan, E. A., Glaspole, I., Glassberg, M. K., Gorina, E., Hopkins, P. M., Kardatzke, D., Lancaster, L., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1402582 · Cited by 3,975

Idiopathic Pulmonary Fibrosis: Diagnosis and Treatment: International Consensus Statement

(2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.2.ats3-00 · Cited by 2,651

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials

Noble, P. W., Albera, C., Bradford, W. Z., Costabel, U., Glassberg, M. K., Kardatzke, D., King, T. E., Lancaster, L., Sahn, S. A., Szwarcberg, J., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60405-4 · Cited by 2,154

An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis: An Update of the 2011 Clinical Practice Guideline

Raghu, G., Rochwerg, B., Zhang, Y., Garcia, C. A. C., Azuma, A., Behr, J., Brozek, J. L., Collard, H. R., Cunningham, W., Homma, S., et al. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201506-1063st · Cited by 1,916

Interleukin-11 disrupts alveolar epithelial progenitor function

Kortekaas, R. K., Geillinger‐Kästle, K. E., Borghuis, T., Belharch, K., Webster, M. J., Timens, W., Burgess, J. K., & Gosens, R. (2023) · ERJ Open Research · doi:10.1183/23120541.00679-2022 · Cited by 26

Engineering Ferroptosis Inhibitors as Inhalable Nanomedicines for the Highly Efficient Treatment of Idiopathic Pulmonary Fibrosis

Guo, M., Peng, T., Wu, C., Pan, X., & Huang, Z. (2023) · Bioengineering · doi:10.3390/bioengineering10060727 · Cited by 22

AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice

Zhang, S., Tong, X., Liu, S., Huang, J., Zhang, L., Zhang, T., Wang, D., & Fan, H. S. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05889-8 · Cited by 24

ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts

Wan, R., Wang, L., Duan, Y., Zhu, M., Li, W., Zhao, M., Yuan, H., Xu, K., Li, Z., Zhang, X., et al. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01702-9 · Cited by 24

Daphnetin Alleviates Bleomycin-Induced Pulmonary Fibrosis through Inhibition of Epithelial-to-Mesenchymal Transition and IL-17A

Park, S.-J., Ryu, H. W., Kim, J.-H., Hahn, H.-J., Jang, H., Ko, S., Oh, S., & Lee, H. (2023) · Cells · doi:10.3390/cells12242795 · Cited by 22

Inhibitor of PD-1/PD-L1: a new approach may be beneficial for the treatment of idiopathic pulmonary fibrosis

Tan, J., Xue, Q., Hu, X., & Yang, J. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-04884-7 · Cited by 23

Repositioning of ezetimibe for the treatment of idiopathic pulmonary fibrosis

Lee, C. H., Kwak, S. H., Han, J., Shin, J. H., Yoo, B., Lee, Y. S., Park, J. S., Lim, B. J., Lee, J. G., Kim, Y. S., et al. (2024) · European Respiratory Journal · doi:10.1183/13993003.00580-2023 · Cited by 22

Nebulized inhalation of nintedanib-loaded biomimetic nano-liposomes attenuated bleomycin-induced interstitial lung fibrosis in mice

Rao, L., Zhu, P., Guo, M., Hu, M., Guo, X., Du, Y., & Xu, G. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102298 · Cited by 23

Increased risk of idiopathic pulmonary fibrosis in inflammatory bowel disease: A nationwide study

Kim, J., Chun, J., Lee, C., Han, K., Choi, S., Lee, J., Soh, H., Choi, K., Park, S., Kang, E. A., et al. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14838 · Cited by 22

Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway

Li, A., Xiao, X., Feng, Z., Chen, X., Liu, L., Lin, L., Lu, J., & Zhang, L. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.114882 · Cited by 22

Glycyrrhizic acid, as an inhibitor of HMGB1, alleviates bleomycin-induced pulmonary toxicity in mice through the MAPK and Smad3 pathways

Zhu, Z.-H., Li, X., He, L., Cai, H.-F., Ye, B., & Wu, Z. (2021) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2021.1939371 · Cited by 22

CCT6A alleviates pulmonary fibrosis by inhibiting HIF-1α-mediated lactate production

Yan, P., Yang, K., Xu, M., Zhu, M., Duan, Y., Li, W., Liu, L., Liang, C., Li, Z., Pan, X., et al. (2024) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjae021 · Cited by 23

Material-driven immunomodulation and ECM remodeling reverse pulmonary fibrosis by local delivery of stem cell-laden microcapsules

Zhang, Y., Zhao, Y., An, C., Guo, Y., Ma, Y., Shao, F., Zhang, Y., Sun, K., Cheng, F., Ren, C., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122757 · Cited by 21

Mosaic loss of chromosome Y, tobacco smoking and risk of age-related lung diseases: insights from two prospective cohorts

Weng, C., Zhao, Y., Song, M., Shao, Z., Pang, Y., Yu, C., Pei, P., Yang, L., Millwood, I. Y., Walters, R. G., et al. (2024) · European Respiratory Journal · doi:10.1183/13993003.00968-2024 · Cited by 20

Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch

Panagiotidis, G., Vásquez‐Pacheco, E., Chu, X., Seeger, W., Agha, E. E., Bellusci, S., & Lingampally, A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1609509 · Cited by 22

Engineerable mesenchymal stem cell-derived extracellular vesicles as promising therapeutic strategies for pulmonary fibrosis

Chen, Y., Li, M., Yang, J., Chen, Y., & Wang, J. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04490-4 · Cited by 22

Adult interstitial lung diseases and their epidemiology

Sésé, L., Khamis, W., Jeny, F., Uzunhan, Y., Duchemann, B., Valeyre, D., Annesi‐Maesano, I., & Nunès, H. (2020) · La Presse Médicale · doi:10.1016/j.lpm.2020.104023 · Cited by 21

Transcription Factor YY1 Inhibits the Expression of THY1 to Promote Interstitial Pulmonary Fibrosis by Activating the HSF1/miR-214 Axis

Chen, L., Yang, Y., Peng, X., Yan, H., Zhang, X., Yin, L., & Yu, H. (2020) · Aging · doi:10.18632/aging.103142 · Cited by 21

Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study

Nakanishi, T., Cerani, A., Forgetta, V., Zhou, S., Allen, R. J., Leavy, O. C., Koido, M., Assayag, D., Jenkins, G. R., Wain, L. V., et al. (2021) · European Respiratory Journal · doi:10.1183/13993003.03979-2020 · Cited by 22

Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases

Mammoliti, O., Jansen, K., Bkassiny, S. E., Palisse, A., Triballeau, N., Bucher, D., Allart, B., Jaunet, A., Tricarico, G. A., Wachter, M. D., et al. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c01066 · Cited by 22

Morin inhibits the transformation of fibroblasts towards myofibroblasts through regulating “PPAR-γ-glutaminolysis-DEPTOR” pathway in pulmonary fibrosis

Miao, Y., Geng, Y., Yang, L., Zheng, Y., Dai, Y., & Wei, Z. (2021) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2021.108923 · Cited by 21

Effects of low-dose pirfenidone on survival and lung function decline in patients with idiopathic pulmonary fibrosis (IPF): Results from a real-world study

Lee, E. G., Lee, T.-H., Hong, Y., Ryoo, J., Heo, J. W., Gil, B. M., Kang, H. S., Kwon, S. S., & Kim, Y. H. (2021) · PLoS ONE · doi:10.1371/journal.pone.0261684 · Cited by 24

How collagen becomes ‘stiff’

Wells, R. G. (2022) · eLife · doi:10.7554/elife.77041 · Cited by 21

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway

Hu, X., Zou, M., Ni, L., Zhang, M., Zheng, W., Liu, B., & Cheng, Z. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.829673 · Cited by 21

Idiopathic pulmonary fibrosis: Diagnosis, biomarkers and newer treatment protocols

Patel, H., Shah, J. R., Patel, D., Avanthika, C., Jhaveri, S., & Gor, K. (2022) · Disease-a-Month · doi:10.1016/j.disamonth.2022.101484 · Cited by 21

RNF130 protects against pulmonary fibrosis through suppressing aerobic glycolysis by mediating c-myc ubiquitination

Zhang, J., Chen, W., Du, J., Chu, L., Zhou, Z., Zhong, W., Liu, D., Huang, H., Huang, Y., Qiao, Y., et al. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.109985 · Cited by 21

Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression

Inoue, R., Yasuma, T., D’Alessandro, V. F., Toda, M., Ito, T., Tomaru, A., D’Alessandro‐Gabazza, C. N., Tsuruga, T., Okano, T., Takeshita, A., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076695 · Cited by 21

Baicalin/ambroxol hydrochloride combined dry powder inhalation formulation targeting lung delivery for treatment of idiopathic pulmonary fibrosis: Fabrication, characterization, pharmacokinetics, and pharmacodynamics

Qi, D., Jia, B., Peng, H., He, J., Pi, J., Guo, P., Zhang, Y., Deng, X., Li, J., & Liu, Z. (2023) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2023.05.017 · Cited by 21

Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validation

Jiang, H., Zhou, R., An, L., Guo, J., Hou, X., Tang, J., Wang, F., & Du, Q. (2023) · Scientific Reports · doi:10.1038/s41598-023-36944-1 · Cited by 21

Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis

Zhao, F., Liu, W. Q., Yue, S., Yang, L., Hua, Q., Zhou, Y., Cheng, H., Luo, Z., & Tang, S. (2019) · Stem Cells International · doi:10.1155/2019/1726743 · Cited by 21

Pulmonary Fibrosis among World Trade Center Responders: Results from the WTC Health Registry Cohort

Li, J., Cone, J. E., Brackbill, R. M., Giesinger, I., Yung, J., & Farfel, M. R. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16050825 · Cited by 23

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis

Ulke, H. M., Mutze, K., Lehmann, M., Wagner, D. E., Heinzelmann, K., Günther, A., Eickelberg, O., & Königshoff, M. (2019) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2019-0047oc · Cited by 22

Myeloid‐specific blockade of Notch signaling alleviates murine pulmonary fibrosis through regulating monocyte‐derived Ly6c lo MHCII hi alveolar macrophages recruitment and TGF‐β secretion

Zhang, N., Yang, K., Bai, J., Yi, J., Gao, C.-C., Zhao, J., Liang, S.-Q., Wei, T., Feng, L., Song, L., et al. (2020) · The FASEB Journal · doi:10.1096/fj.201903086rr · Cited by 21

LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway

Liu, P., Zhao, L., Gu, Y., Zhang, M., Gao, H., & Meng, Y. (2021) · Respiratory Research · doi:10.1186/s12931-021-01632-z · Cited by 21

The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice

Yu, Y., Liu, X., Zhao, Z., Xu, Z., Qiao, Y., Zhou, Y., Qiao, H., Zhong, J., Dai, J., & Suo, G. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.747223 · Cited by 22

CD109, a master regulator of inflammatory responses

Batal, A., Garousi, S., Finnson, K. W., & Philip, A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1505008 · Cited by 21

Succinate promotes pulmonary fibrosis through GPR91 and predicts death in idiopathic pulmonary fibrosis

He, Y., Han, Y., Zou, L., Yao, T., Zhang, Y., Lv, X., Jiang, M., Long, L., Li, M., Cheng, X., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-64844-5 · Cited by 20

Translating Idiopathic pulmonary fibrosis guidelines into clinical practice

Cordeiro, C. R., & Morais, A. (2020) · Pulmonology · doi:10.1016/j.pulmoe.2020.05.017 · Cited by 20

Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells

Duan, J., Guan, X., Yang, H., Mei, W.-X., Chen, P., Tao, J., Li, Q., & Zhou, Y. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.108211 · Cited by 21

Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis

Dong, Y., Tang, B., Wang, Q., Zhou, L., Li, C., Zhang, X., Sun, D., Sun, X., Zhang, X., Xiong, B., et al. (2021) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00808-z · Cited by 20

Management of BMI Is a Potential New Approach for the Prevention of Idiopathic Pulmonary Fibrosis

Ma, Y., Feng, C., Tang, H., Deng, P., Li, Y., Wang, J., Zhu, S., & Zhu, L. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.821029 · Cited by 20

NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition

Li, M., Shu-Li, Z., Yuan, F., Han, H., Shao-Jun, L., Sheng-Xiong, T., Jia-Yu, T., Fang, X., & Dan, F. (2022) · Respiratory Research · doi:10.1186/s12931-022-02044-3 · Cited by 20

Promises and Challenges of Cell-Based Therapies to Promote Lung Regeneration in Idiopathic Pulmonary Fibrosis

Egea-Zorrilla, A., Vera, L., Sáez, B., & Pardo–Saganta, A. (2022) · Cells · doi:10.3390/cells11162595 · Cited by 21

Role of Circular RNAs in Pulmonary Fibrosis

Zhou, J. P., Chen, Y., He, M., Li, X., & Wang, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810493 · Cited by 21

Component analysis and anti-pulmonary fibrosis effects of Rosa sterilis juice

Wang, L., Li, Y., Xia, R., Zheng, X., Li, X., Wu, S., Zhang, Q., Li, S., Deng, Y., Yao, Y., et al. (2022) · Food & Function · doi:10.1039/d2fo02758e · Cited by 22

TRIB3 promotes pulmonary fibrosis through inhibiting SLUG degradation by physically interacting with MDM2

Lv, X., Liu, S., Liu, C., Li, Y., Zhang, T., Qi, J., Li, K., Hua, F., Cui, B., Zhang, X., et al. (2023) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2023.01.008 · Cited by 21

Protective role of baicalin in the dynamic progression of lung injury to idiopathic pulmonary fibrosis: A meta-analysis

Jiang, J., Kao, T.-C., Hu, S., Li, Y., Feng, W., Guo, X., Zeng, J., & Ma, X. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154777 · Cited by 20

4-OI ameliorates bleomycin-induced pulmonary fibrosis by activating Nrf2 and suppressing macrophage-mediated epithelial-mesenchymal transition

Wu, Y., Zhang, Y., Jiang, F., He, S., Zhang, Y., Chen, D., Tong, Y., Nie, Y., & Pang, Q. (2023) · Inflammation Research · doi:10.1007/s00011-023-01733-z · Cited by 21

Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system

Li, H., Wang, Y., Chen, T., Gao, Y., Ling, S., Yang, Y., Gao, Y., Huo, W., & Zhang, G. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116979 · Cited by 20

Gas6-Axl signal promotes indoor VOCs exposure-induced pulmonary fibrosis via pulmonary microvascular endothelial cells–fibroblasts cross-talk

Liu, Q., Niu, Y., Pei, Z., Yang, Y., Xie, Y., Wang, M., Wang, J., Wu, M., Zheng, J., Yang, P., et al. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.134786 · Cited by 20

Therapeutic targets and early stage clinical trials for pulmonary fibrosis

Sato, S., Yanagihara, T., & Kolb, M. R. J. (2018) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2019.1554054 · Cited by 20

Tannic acid alleviates experimental pulmonary fibrosis in mice by inhibiting inflammatory response and fibrotic process

Rajasekar, N., Sivanantham, A., Kar, A. G., Mahapatra, S. K., Ahirwar, R., Thimmulappa, R. K., Paramasivam, S. G., & Rajasekaran, S. (2020) · Inflammopharmacology · doi:10.1007/s10787-020-00707-5 · Cited by 20

Global research hotspots and research trends on idiopathic pulmonary fibrosis: a bibliometric and visualization analysis

Ma, Y., Zhou, R., & Wu, Q. (2021) · Annals of Palliative Medicine · doi:10.21037/apm-21-1836 · Cited by 20

Gypenosides Attenuate Pulmonary Fibrosis by Inhibiting the AKT/mTOR/c-Myc Pathway

Liu, S., Yang, Q., Dong, B., Qi, C., Yang, T., Li, M., He, S., Liu, B., & Wu, J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.806312 · Cited by 20

Inhibition of HIF-1α ameliorates pulmonary fibrosis by suppressing M2 macrophage polarization through PRMT1/STAT6 signals

Liang, J., Ran, Y., Hu, C., Zhou, J., Lin, Y., Su, W., Liu, Z., & Xi, J. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113931 · Cited by 19

Ginseng and Platycodon grandiflorum ameliorated pulmonary fibrosis and inflammation targeting TLR4-P2X7r/NLRP3 signaling pathway

Dou, J.-Y., Wu, Y., Gao, C., Zheng, S., Wang, C., Dai, X., Lian, L., Cui, Z., Nan, J., & Wu, Y. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.119913 · Cited by 19

Transcriptomic profiling reveals disease-specific characteristics of epithelial cells in idiopathic pulmonary fibrosis

Boesch, M., Baty, F., Brutsche, M. H., Tamm, M., Roux, J., Knudsen, L., Gazdhar, A., Geiser, T., Khan, P., & Hostettler, K. (2020) · Respiratory Research · doi:10.1186/s12931-020-01414-z · Cited by 19

A Novel Fibroblast Reporter Cell Line for in vitro Studies of Pulmonary Fibrosis

Németh, J., Schundner, A., Quast, K., Winkelmann, V. E., & Frick, M. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.567675 · Cited by 20

Tianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation of Arginase-Ornithine Pathway

Zhang, L., Qu, S., Wang, L., Wang, C., Yu, Q., Zhang, Z., Diao, Y., Zhang, B., Li, Y., Shi, Y., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.661129 · Cited by 20

Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway

Wang, Z., Feng, F., He, H., Wu, Q., Gu, C., Hrovat, J., Peng, W., Xu, Y., Han, D., Yang, P., et al. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153599 · Cited by 19

Diagnosis and Management of Fibrotic Interstitial Lung Diseases

Collins, B. F., & Luppi, F. (2021) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2021.03.008 · Cited by 21

Introduction to Lung Diseases

Jadhav, S., Singh, H., Hussain, S., Gilhotra, R. M., Mishra, A., Prasher, P., Krishnan, A., & Gupta, G. (2021) · Springer eBooks · doi:10.1007/978-981-33-6827-9_1 · Cited by 21

The Role of Extracellular Vesicles in Idiopathic Pulmonary Fibrosis Progression: An Approach on Their Therapeutics Potential

Ramírez-Hernández, A. A., Velázquez-Enríquez, J. M., Santos-Álvarez, J. C., López-Martínez, A., Reyes-Jiménez, E., Torres, G., González-García, K., Vásquez-Garzón, V. R., & Baltiérrez‐Hoyos, R. (2022) · Cells · doi:10.3390/cells11040630 · Cited by 19

Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway

Li, Z., Geng, J., Xie, B., He, J., Wang, J., Peng, L., Hu, Y., Dai, H., & Wang, C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.834604 · Cited by 19

Diagnosis and management of idiopathic pulmonary fibrosis

Joshi, V. V., & Nagji, Z. (2022) · Prescriber · doi:10.1002/psb.1998 · Cited by 19

TREM-1 exacerbates bleomycin-induced pulmonary fibrosis by aggravating alveolar epithelial cell senescence in mice

Xiong, J., Duan, J., Jiang, N., Zhang, C., Zhong, W., Yang, J., Liu, Y., Su, F., Zhou, Y., Li, D., et al. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109339 · Cited by 20

The emerging importance of immunophilins in fibrosis development

Alqudah, A. M., Abudalo, R. A., Qnais, E. Y., Wedyan, M. A., Oqal, M. K., & McClements, L. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04591-1 · Cited by 19

Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling

Li, J., Li, K., Tian, Y., Zhao, P., Liu, X., Li, M., & Bai, Y. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154604 · Cited by 19

Qimai Feiluoping decoction inhibits mitochondrial complex I-mediated oxidative stress to ameliorate bleomycin-induced pulmonary fibrosis

Ding, L., Yang, Y., Wang, Z., Su, H., Li, Y., Ma, J., Bao, T., Qi, H., Song, S., Li, J., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154707 · Cited by 19

Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis

Yuan, S., Zuo, B., Zhou, S., Wang, M., Tan, K.-Y., Chen, Z., & Cao, W.-F. (2023) · Drug Design Development and Therapy · doi:10.2147/dddt.s404710 · Cited by 19

The emerging roles of SUMOylation in pulmonary diseases

Zheng, X., Wang, L., Zhang, Z., & Tang, H. (2023) · Molecular Medicine · doi:10.1186/s10020-023-00719-1 · Cited by 23

The tolerability and efficacy of antifibrotic therapy in patients with idiopathic pulmonary fibrosis: Results from a real-world study

Zhao, R., Xie, B., Wang, X., Zhang, X., Ren, Y., Wang, C., & Dai, H. (2024) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2024.102287 · Cited by 22

Prognostic implication of 1-year decline in diffusing capacity in newly diagnosed idiopathic pulmonary fibrosis

Lee, H., Kim, S. Y., Park, Y. S., Choi, S. M., Lee, J. H., & Park, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-59649-5 · Cited by 19

CYLD/HDAC6 signaling regulates the interplay between epithelial-mesenchymal transition and ciliary homeostasis during pulmonary fibrosis

Ni, H., Chen, M., Dong, D. F., Zhou, Y., Cao, Y., Ge, R., Luo, X., Wang, Y., Dong, X., Zhou, J., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06972-4 · Cited by 19

NLRP3 inflammasome activation contributes to the development of the pro-fibrotic phenotype of lung fibroblasts

Nguyen, T.-H., Nguyen, H.-H.-N., Nguyen, T.-D., Tran, V. T.-H., Nguyen, H. A., & Pham, D. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116496 · Cited by 19

Efficacy and Safety of Traditional Chinese Medicine in Idiopathic Pulmonary Fibrosis: A Meta‐Analysis

Ji, K., Jian-ling, M., Liangmin, W., Li, N., Dong, S., & Li-qing, S. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/1752387 · Cited by 20

Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin

河原明奈, Mizuta, R., Fujisawa, M., Ito, T., Li, C., Nakamura, K., Sun, C., Kuwabara, M., Kitabatake, M., Yoshimura, T., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-73752-3 · Cited by 17

A novel prognostic signature for idiopathic pulmonary fibrosis based on five-immune-related genes

Qiu, L., Gong, G., Wu, W., Li, N., Li, Z., Chen, S., Li, P., Chen, T., Zhao, H., Hu, C., et al. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-4545 · Cited by 18

CoQ10 enhances the efficacy of airway basal stem cell transplantation on bleomycin-induced idiopathic pulmonary fibrosis in mice

Liu, H., Liu, S., Jiang, J., Zhang, Y., Luo, Y., Zhao, J., Xu, J., Xie, Y., Liao, W., Wang, W., et al. (2022) · Respiratory Research · doi:10.1186/s12931-022-01964-4 · Cited by 19

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Idiopathic Pulmonary Fibrosis Microenvironment Targeted Delivery

Sang, L., Guo, X., Fan, H., Shi, J., Hou, S., & Lv, Q. (2022) · Cells · doi:10.3390/cells11152322 · Cited by 20

Regulation of idiopathic pulmonary fibrosis: a cross-talk between TGF-β signaling and MicroRNAs

Wang, S., Yu, H., Liu, S., Liu, Y., & Gu, X. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1415278 · Cited by 21

Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis

Chen, C., Wang, J., Cheng, M., Xie, H., Li, W., & Zhang, C. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107587 · Cited by 22

Single Cell RNA ‐Seq Identifies Cell Subpopulations Contributing to Idiopathic Pulmonary Fibrosis in Humans

Zhang, T., Hou, Z., Ding, Z., Wang, P., Pan, X., & Li, X. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70402 · Cited by 18

Inhalable nucleic acid therapeutics for chronic pulmonary disease: Progress, challenges, and prospects

Wang, Y., Xuan, W., Mao, C., & Liu, Y. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.07.068 · Cited by 25

Licence to kill senescent cells in idiopathic pulmonary fibrosis?

Mailleux, A., & Crestani, B. (2017) · European Respiratory Journal · doi:10.1183/13993003.01360-2017 · Cited by 18

TRIM proteins in fibrosis

Qian, H., & Chen, L. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112340 · Cited by 18

Tetrathiomolybdate Treatment Attenuates Bleomycin-Induced Angiogenesis and Lung Pathology in a Sheep Model of Pulmonary Fibrosis

Derseh, H. B., Perera, K. U. E., Dewage, S. N. V., Stent, A. W., Koumoundouros, E., Organ, L. A., Pagel, C. N., & Snibson, K. J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.700902 · Cited by 19

Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway

Wang, Y., Sun, S., Wang, K., Zhang, M., Li, M., Zan, Y., Huang, Q., Wu, S., Zhao, W., Xu, W. D., et al. (2022) · Mediators of Inflammation · doi:10.1155/2022/6755407 · Cited by 19

Ameliorative Effects of Arctigenin on Pulmonary Fibrosis Induced by Bleomycin via the Antioxidant Activity

Wang, Y., Li, X., Pu, S., Wang, X. D., Guo, L., Zhang, L., & Wang, Z. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/3541731 · Cited by 18

Mesenchymal stromal cell therapy for chronic lung diseases: experimental and clinical evidence

Melo, M. M., Cruz, F. F., & Rocco, P. R. M. (2023) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2023.2196015 · Cited by 18

Gracillin relieves pulmonary fibrosis by suppressing the STAT3 axis

Xie, M., Yang, L., Cheng, J., Qu, H., Gu, Y.-T., Ding, C., Xu, X., Zhao, C., Huang, X., & Wang, L. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116704 · Cited by 18

TrxR/Trx inhibitor butaselen ameliorates pulmonary fibrosis by suppressing NF-κB/TGF-β1/Smads signaling

Chen, Y., Yin, H., Sun, J., Zhang, G., Zhang, Y., & Zeng, H. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115822 · Cited by 18

The usual Interstitial pneumonia pattern in autoimmune rheumatic diseases

Luppi, F., Manfredi, A., Faverio, P., Andersen, M. B., Bono, F., Pagni, F., Salvarani, C., Bendstrup, E. M., & Sebastiani, M. (2023) · BMC Pulmonary Medicine · doi:10.1186/s12890-023-02783-z · Cited by 18

Tuftelin1 drives experimental pulmonary fibrosis progression by facilitating stress fiber assembly

Niu, C., Xu, K., Hu, Y., Jia, Y., Yang, Y., Pan, X., Wan, R., Lian, H., Wang, Q., Yang, J., et al. (2023) · Respiratory Research · doi:10.1186/s12931-023-02633-w · Cited by 18

Experimental autotaxin inhibitors for the treatment of idiopathic pulmonary fibrosis

Simonetti, J., Ficili, M., Sgalla, G., & Richeldi, L. (2024) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2024.2305126 · Cited by 18

TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving Endothelial-to-Mesenchymal Transition (EndMT)

Gaikwad, A. V., Eapen, M. S., Dey, S., Bhattarai, P., Shahzad, A. M., Chia, C., Jaffar, J., Westall, G. P., Sutherland, D. P., Singhera, G. K., et al. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13041160 · Cited by 18

Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells

Ren, C., Wang, Q., Fan, S., Mi, T., Zhang, Z., & He, D. (2024) · Inflammation · doi:10.1007/s10753-024-02006-5 · Cited by 18

IL20Rb aggravates pulmonary fibrosis through enhancing bone marrow derived profibrotic macrophage activation

Zhu, J., Jiang, Q., Gao, S., Xia, Q., Zhang, H., Liu, B., Zhao, R., Jiang, H., Li, X., Xu, A., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107178 · Cited by 18

Exploring ABHD5 as a Lipid-Related Biomarker in Idiopathic Pulmonary Fibrosis: Integrating Machine Learning, Bioinformatics, and In Vitro Experiments

Liao, Y., Peng, X., Yang, Y., Zhou, G., Chen, L., Yang, Y., Li, H., Chen, X., Guo, S., Zuo, Q., et al. (2024) · Inflammation · doi:10.1007/s10753-024-02107-1 · Cited by 18

New treatment directions for IPF: current status of ongoing and upcoming clinical trials

Macagno, F., Varone, F., Leone, P. M., Mari, P., Panico, L., Berardini, L., & Richeldi, L. (2017) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2017.1335601 · Cited by 19

Pronostic et exacerbations aiguës de la fibrose pulmonaire idiopathique

Uzunhan, Y. (2010) · Revue des Maladies Respiratoires Actualités · doi:10.1016/s1877-1203(10)70127-0

Idiopathic Pulmonary Fibrosis: An Overview

May, J., & Jenkins, G. R. (2026) · British Journal of Hospital Medicine · doi:10.31083/bjhm50844 · Cited by 1

New Aspects of Idiopathic Pulmonary Fibrosis

Molina‐Molina, M., Vicens, V., & Estany, S. (2010) · Clinical Pulmonary Medicine · doi:10.1097/cpm.0b013e3181e4bb22 · Cited by 1

Re-dimensioning the treatment paradigm in idiopathic pulmonary fibrosis

Richeldi, L. (2018) · Monografías de Archivos de Bronconeumología

Idiopathic pulmonary fibrosis and progressive fibrotic interstitial lung disease

Evans, P., Rowlands, E., & Hope‐Gill, B. (2023) · Medicine · doi:10.1016/j.mpmed.2023.09.001 · Cited by 3