The DOI matches its Crossref record; 142 of the 143 references it cites were found in a registry or an index.
Coeliac disease
Abstract
Coeliac disease occurs in about 1% of people in most populations. Diagnosis rates are increasing, and this seems to be due to a true rise in incidence rather than increased awareness and detection. Coeliac disease develops in genetically susceptible individuals who, in response to unknown environmental factors, develop an immune response that is subsequently triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe malabsorption to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal villous atrophy, and most patients have circulating antibodies against tissue transglutaminase; in children, European guidelines allow a diagnosis without a duodenal biopsy provided that strict symptomatic and serological criteria are met. Although a gluten-free diet is an effective treatment in most individuals, a substantial minority develop persistent or recurrent symptoms. Difficulties adhering to a gluten-free diet have led to the development of non-dietary therapies, several of which are undergoing trials in human beings.
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“Coeliac Disease (CD) is a chronic, immune mediated disorder for which the only treatment consists of lifelong adherence to a strict gluten-free diet (GFD) (1).”
Citations
Cites
Husby, S., Koletzko, S., Korponay‐Szabó, I. R., Mearin, M. L., Phillips, A., Shamir, R., Troncone, R., Giersiepen, K., Branski, D., Catassi, C., et al. (2012) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31821a23d0 · Cited by 2,683
Identification of tissue transglutaminase as the autoantigen of celiac disease
Dieterich, W., Ehnis, T., Bauer, M., Donner, P., Volta, U., Riecken, E. O., & Schuppan, D. (1997) · Nature Medicine · doi:10.1038/nm0797-797 · Cited by 2,021
The Oslo definitions for coeliac disease and related terms
Ludvigsson, J. F., Leffler, D. A., Bai, J. C., Biagi, F., Fasano, A., Green, P. H. R., Hadjivassiliou, M., Kaukinen, K., Kelly, C. P., Leonard, J. N., et al. (2013) · Gut · doi:10.1136/gutjnl-2011-301346 · Cited by 1,721
Self-citationACG Clinical Guidelines: Diagnosis and Management of Celiac Disease
Rubio‐Tapia, A., Hill, I. D., Kelly, C. P., Calderwood, A. H., & Murray, J. A. (2013) · The American Journal of Gastroenterology · doi:10.1038/ajg.2013.79 · Cited by 1,705
Prevalence of Celiac Disease in At-Risk and Not-At-Risk Groups in the United States
Fasano, A., Berti, I., Gerarduzzi, T., Not, T., Colletti, R. B., Drago, S., Elitsur, Y., Green, P. H. R., Guandalini, S., Hill, I. D., et al. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.3.286 · Cited by 1,702
Self-citationStructural Basis for Gluten Intolerance in Celiac Sprue
Shan, L., Molberg, Ø., Parrot, I., Hausch, F., Filiz, F., Gm, G., Sollid, L. M., & Khosla, C. (2002) · Science · doi:10.1126/science.1074129 · Cited by 1,576
Molberg, Ø., McAdam, S. N., Körner, R., Quarsten, H., Kristiansen, C., Madsen, L. S., Fugger, L. H., Scott, H., Norén, O., Roepstorff, P., et al. (1998) · Nature Medicine · doi:10.1038/nm0698-713 · Cited by 1,166
Ludvigsson, J. F., Bai, J. C., Biagi, F., Card, T. R., Ciacci, C., Ciclitira, P. J., Green, P. H. R., Hadjivassiliou, M., Holdoway, A., van Heel, D. A., et al. (2014) · Gut · doi:10.1136/gutjnl-2013-306578 · Cited by 1,140
Self-citationMustalahti, K., Catassi, C., Reunanen, A., Fabiani, E., Heier, M., McMillan, S. A., Murray, L., Metzger, M.-H., Gasparin, M., Bravi, E., et al. (2010) · Annals of Medicine · doi:10.3109/07853890.2010.505931 · Cited by 761
Increased Prevalence and Mortality in Undiagnosed Celiac Disease
Rubio‐Tapia, A., Kyle, R. A., Kaplan, E. L., Johnson, D. R., Page, W. F., Erdtmann, F. J., Brantner, T. L., Kim, W. R., Phelps, T. K., Lahr, B. D., et al. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.03.059 · Cited by 761
Research works printed but not linked: 1
- Choung, 2016, Less hidden celiac disease but increased gluten avoidance without a diagnosis in the United States: findings from the National Health and Nutrition Examination surveys from 2009 to 2014, Mayo Clin Proc
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Sorted by citations
Pasricha, S.-R., Tye-Din, J., Muckenthaler, M. U., & Swinkels, D. W. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32594-0 · Cited by 1,069
Catassi, C., Verdu, E. F., Bai, J. C., & Lionetti, E. (2022) · The Lancet · doi:10.1016/s0140-6736(22)00794-2 · Cited by 547
Incidence of Celiac Disease Is Increasing Over Time: A Systematic Review and Meta-analysis
King, J. A., Jeong, J., Underwood, F. E., Quan, J., Panaccione, N., Windsor, J. W., Coward, S. B., deBruyn, J. C. C., Ronksley, P. E., Shaheen, A. A., et al. (2020) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000523 · Cited by 455
Self-citationZhang, F., Aschenbrenner, D., Yoo, J. Y., & Zuo, T. (2022) · The Lancet Microbe · doi:10.1016/s2666-5247(22)00203-8 · Cited by 424
Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review
Stillhart, C., Vučićević, K. M., Augustijns, P., Basit, A. W., Batchelor, H. K., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., et al. (2020) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2020.105280 · Cited by 343
Metadata
- Authors
- Lebwohl, B., Sanders, D. S., & Green, P. H. R.
- Affiliations
- Columbia University Irving Medical Center (US)
- Royal Hallamshire Hospital (GB)
- Corresponding author
- Green, Peter H R
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 391
- Issue
- 10115
- Pages
- 70-81
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W4211144941
- Cited by
- 1,065
- References
- 143
- Citations by year
- 2026: 98 · 2025: 101 · 2024: 138 · 2023: 115 · 2022: 142 · 2021: 177 · 2020: 144 · 2019: 90 · 2018: 58
- FWCI
- 13.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Wheat and Barley Genetics and Pathology
- Health Sciences › Medicine › Gastroenterology › Eosinophilic Esophagitis
- Keywords
- celiac disease, gluten, duodenal villous atrophy, anti-tissue transglutaminase antibodies, serological diagnosis, duodenal biopsy, gluten-free diet, malabsorption, incidence, genetic susceptibility, environmental triggers
- MeSH terms
- Celiac Disease, Humans
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