Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 394

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

Open access
Pan, Hongchao, Peto, Richard, Henao Restrepo, Ana Maria, Preziosi, Marie-Pierre, Sathiyamoorthy, Vasee, Karim, Quarraisha Abdool, Alejandria, Marissa, Hernàndez García, César, Kieny, Marie-Paule, Malekzadeh, Reza, Murthy, Srinivas, Reddy, K. Srinath, Periago, Mirta Roses, Hanna, Pierre Abi, Abutidze, Akaki, Ader, Florence, Al-Bader, Abdullah, Alhasawi, Almonther, Allum, Emma, Al Mawali, Adhra, Alotaibi, Athari, Alvarez- Moreno, Carlos, Appadoo, Sheila, Arts, Derk, Asiri, Abdullah, Aukrust, Pål, Barratt-Due, Andreas, Genetu Bayih, Abebe, Beaumont, Helena, Bellani, Samir, Benassi, Virginia, Bhargava, Balram, Branca, Mattia, Cappel-Porter, Heike, Cerrato, Nery, Cheick Haidara, Fadima, Chow, Ting Soo, Como, Nadia, Eustace, Joe, Gabunia, Tamar, García, Patricia, Godbole, Sheela, Gotuzzo, Eduardo, Griskevicius, Laimonas, Hamra, Rasha, Hassan, Mariam, Hassany, Mohamed, Hutton, David, Irmansyah, Irmansyah, Jancoriene, Ligita, Khamis, Faryal, Kirwan, Jana, Kumar, Suresh, Lennon, Peter, Lopardo, Gustavo, Lydon, Patrick, Magrini, Nicola, Manevska, Suzana, Manuel, Oriol, McGinty, Sybil, Medina, Marco, Mesa Rubio, Maria Lucia, Miranda Montoya, Maria Consuelo, Nel, Jeremy, Nunes, Estevao, Perola, Markus, Portoles, Antonio, Rasmin, Menaldi, Raza, Aun, Rees, Helen, Reges, Paula, Rogers, Chris, Salami, Kolawole, Salvadori, Marina, Sauermann, Mamatha, Sinani, Narvina, Sow, Samba, Sterne, Jonathan AC, Stevanovikj, Milena, Tacconelli, Evelina, Tavares Maltez, Fernando Manuel, Teferi, Mekonnen, Tikkinen, Kari, Trelle, Sven, Tsertsvadze, Tengiz, Zaid, Hala, Røttingen, John-Arne, Swaminathan, Soumya, Ryan, Michael, Gjermeni, Nevila, Meta, Esmeralda, Aguila, Damian, Alonso, Ignacio, Altamirano, Marcos, Alvarez, María, Alzola, Rodrigo, Arce, Veronica, Arribillaga, Patricia, Avila, Rafael, Balbuena, Juan, Barcelona, Laura, Barletta, José, Benedetti, María, Berdiñas, Verónica, Burgui, Julieta, Caimi, Sabrina, Carrillo, Juan, Carrizo, Juan, Castelli, Juan, Cazaux, Alexis, Cervellino, Flavia, Chalco, Angelo, Chediack, Viviana, Cunto, Eleonora, D'Amico, Nicolàs, de Vedia, Lautaro, Delgado, Carolina, Di Pilla, Debora, Díaz, Miguel, Díaz Aguiar, Pablo, Domínguez, Cecilia, Ellero, Leonor, Farina, Javier, Fernàndez, José, Ferreyra, Roxana, Filippi, María, Fogar, Carolina, Frare, Pablo, Giudiche, Celeste, Golikow, Mariana, Gomez, Maria Georgina, Hermida, Laura, Hurtado, Mariano, Jacobo, Mariela, Jaume, Martin, Laplume, Diego, Lescano, María, Lista, Nicolàs, Loiacono, Flavia, López, Ana Belen, Losso, Marcelo, Luna, Cecilia, Lupo, Sergio, Marianelli, Leonardo, Martin, Anabella, Masciottra, Florencia, Mykietiuk, Analía, Orellano, Lorena, Pachioli, Valeria, Padilla, María José, Pallavicini, Cecilia, Patroso, Jazmin, Perez Blanco, Luz, Presas, Jose Louis, Provenzano, Matias, Lavera, Lorena, Reichert, Viviana, Riveros, Florencia, Rodríguez, Alejandra, Rolon, María José, Salvay, Carolina, Simonetta, María, Sisto, Alicia, Themines, Sandra, Tito, Fernando, Toibaro, Javier, Torales, Graciela, Verón, Luciano, Vizzotti, Carla, Egle, Alexander, Greil, Richard, Joannidis, Michael, Altdorfer, Antoine, Belkhir, Leila, Fraipont, Vincent, Hites, Maya, Arruda, Erico, Breda, Giovanni, Colussi, Arthur, Corradi, Miran, Croda, Julio, Duani, Helena, João, Esaú, Machado, Elizabeth, Mello, Fernanda, Miranda Filho, Demócrito, Monteiro, Poliana, Nunes, Ceuci, Pereira Junior, Luiz Carlos, Pinto, Gustavo, Raboni, Sonia, Ramos, Marcelo, Ruffing, Leonardo, Santos, Valdilea, Souza, Tamara, Medeiros, Melissa, Schwarzbold, Alexandre, Ali, Karim, Azher, Tanweer, Bellemare, David, Binnie, Alexandra, Borgia, Sergio, Cavayas, Yiorgos Alexandros, Chagnon, Nicholas, Cheng, Matthew, Cloutier, Eve, Conly, John, Costiniuk, Cecilia, Daneman, Nick, Douglas, James, Downey, Catarina, Duan, Erick, Durand, Medeline, English, Shane, Farjou, George, Fera, Evadiki, Fontela, Patricia, Fowler, Rob, Fralick, Mike, Gamble, David Gregory, Geagea, Anna, Grant, Jennifer, Harrison, Luke, Havey, Thomas, Hoang, Holly, Kelly, Lauren, Keynan, Yoav, Khwaja, Kosar, Klein, Marina, Kolan, Christophe, Kronfli, Nadine, Lamontagne, Francois, Lee, Nelson, Lee, Todd, Lim, Rachel, Lostun, Alexandra, MacIntyre, Erika, Malhamé, Isabelle, Martin-Carrier, Francois, McGuinty, Marlee, Munan, Matthew, O'Neil, Conar, Ovakim, Daniel, Papenburg, Jesse, Parhar, Ken, Parvathy, SeemaNair, Perez-Patrigeon, Santiago, Rishu, Asgar, Rushton, Moira, Scherr, Kim, Schwartz, Kevin, Semret, Makeda, Silverman, Micahel, Singh, Ameeta, Sligl, Wendy, Smith, Stephanie, Somayaji, Ranjani, Tan, Darrell, Tran, Tuong-Vi, Tremblay, Alain, Tsang, Jennifer, Turgeon, Alexis, Vakil, Erik, Weatherald, Jason, Yansouni, Cedric, Zarychanski, Ryan, Aristizabal, Claudia, Bravo, Juan, Caicedo, Monica, Chacón, Julio, Garzón, Diego, Guevara, Fredy, Lozano-Gonzàlez, Silvia, Macareno, Hugo, Montañez-Ayala, Anita, Oñate, Jose, Rojas-Gambasica, Jose, Rosso, Fernando, Saavedra, Carlos, Valderrama, Sandra, Vàquiro-Herrera, Eliana, Varón-Vega, Fabio, Zuluaga, Ivan, Abdel Baki, Amin, Abdelbary, Akram, Abdel-Razek, Wael, Amin, Wagdi, Asem, Noha, Elassal, Gehan, Elshesheny, Marwa, Fathy, Mohamed, Fathy, Naglaa, Fayed, Notaila, Hammam, Ahmed, Hassany, Sahar, Ibrahim, Hamdy, Kamal, Ehab, Masoud, Hossam, Mohamed, Maryam, Mohamed Gouda, Abdullah, Moustafa, Ehab, Okasha, Shaimaa, Rafik, Ahmed, Said, Ahmed, Sedky, Asmaa, Solyman Kabil, Mohamed, Tarek, Sara, Tharwat, Ahmed, Zaky, Samy, Abegaz, Emawayish Tesema, Bekele, Zelalem Mekonnen, Asfaw, Filmona Mekuria, Tegegne, Netsanet Aragaw, Teklemariam, Miheret Fikre, Nigusse, Frehiwot Tamiru, Achalu, Daniel Legesse, Weldegergs, Shewit Tesfagabr, Huluka, Dawit Kebede, Tereda, Addisu Birhanu, Ala-Kokko, Tero, Delany, Jutta, Ekroos, Heikki, Hankkio, Riina, Haukipää, Mia, Hetemäki, Iivo, Holma, Pia, Holmberg, Ville, Horstia, Saana, Jalkanen, Ville, Jämsänen, Toni, Järventie, Juuso, Järvinen, Petrus, Kalliala, Ilkka, Kauma, Heikki, Kilpeläinen, Tuomas, Kreivi, Hanna-Riikka, Kuitunen, Ilari, Lamminmäki, Satu, Mäkinen, Laura, Mäntylä, Jarkko, Mattila, Tiina, Myllärniemi, Marjukka, Niskanen, Joni, Nykänen, Taina, Nyqvist, Miro, Paajanen, Juuso, Partanen, Terhi, Patovirta, Riitta-Liisa, Paukkeri, Erja-Leena, Puusti, Emmi, Renner, Andreas, Reponen, Emma, Risku, Sari, Rosberg, Tuomas, Rutanen, Jarno, Säilä, Petrus, Salonen, Päivi, Sinisalo, Marjatta, Sivenius, Katariina, Tuominen, Susanna, Aboab, Jerone, Alfaiate, Toni, Andrejak, Claire, Andreu, Pascal, Belhadi, Drifa, Benezit, Francois, Botelho-Nevers, Elisabeth, Bouadma, Lila, Bougon, David, Bouiller, Kevin, Bounes, Fanny, Boyer, Alexandre, Bruel, Cédric, Buffet, Alexandre, Burdet, Charles, Cazanave, Charles, Chabertier, Cyrille, Clere-Jehl, Rapahel, Costagliola, Dominique, Courjon, Johan-Victor, Crockett, Flora, Danion, Francois, Dechanet, Aline, Dellamonica, Jean, Delmas, Christelle, Diallo, Alpha, Djossou, Felix, Dubost, Clement, Dupont, Axelle, Epaulard, Olivier, Faure, Emmmanuel, Faure, Karine, Fayol, Antoine, Figueiredo, Samy, Fougerou, Claire, Gaborit, Benjamin, Gaci, Rostane, Gagneux-Brunon, Amandine, Gallien, Sebastien, Garot, D, Goehringer, Francois, Gruson, Didier, Hinschberger, Olivier, Hulot, Jean-Sebastien, Jaureguiberry, Stephane, Jean-Michel, Vanessa, Kerneis, Solen, Kimmoun, Antoine, Klouche, Kada, Lachatre, Marie, Lacombe, Karine, Laine, Fabrice, Lanoix, Jean Philippe, Laribi, Samira, Launay, Odile, Laviolle, Bruno, Le Moing, Vincent, Le Pavec, Jerome, Lebeaux, David, Leroy, Sylvie, Lescure, Xavier, Livrozet, Marine, Makinson, Alain, Malvy, Denis, Marquette, Charles-Hugo, Martin-Blondel, Guillaume, Mayaux, Julien, Mekontso Dessap, Armand, Mentre, France, Mercier, Noemie, Meziani, Ferhat, Molina, Jean Michel, Mootien, Yoganaden, Mourvillier, Bruno, Navellou, Jean Christoph, Noret, M, Peiffer- Smadja, Nathan, Peytavin, Gilles, Pialoux, Gilles, Pilmis, Benoît, Piroth, Lionel, Poindron, Vincent, Poissy, Julien, Pourcher, Valerie, Quenot, Jean Pierre, Raffi, Francois, Reignier, Jean, Richard, Jean Christoph, Robert, Céline, Saillard, Juliette, Sayre, Naomi, Senneville, Eric, Stefan, Francois, Tellier, Marie Capucine, Terzi, Nicolas, Textoris, Julien, Thiery, Guillame, Timsit, Jean Francois, Tolsma, Violaine, Tubiana, Sarah, Wallet, Florent, Yazdanpanah, Yazdan, Zerbib, Yoann, Aguilar, Carlos, Erazo, Laura, Fiallos, Angel, Figueroa, Rosbinda, Flores, Juan Jose, Melendez, Lesddyy, Moncada, Wendy, Abraham, Ooriapadickal Cherian, Acharya, Chetankumar, Aedula, Vinaya Sekhar, Aggarwal, Richa, Agrawal, Nishant, Agrawal, Umang, Agrawal, Abhishekh, Ahmad, Mohammad, Atal, Shubham, Babu, Avinash, Baidya, Dalim Kumar, Balachandran, Amith, Bangar, Rakhee, Bhadade, Rakesh, Bhandari, Sudhir, Bhapal, Meghavi, Bhardwaj, Pankaj, Bhati, Gaurav, Bhatia, Pradeep, Bhatt, Krishnakant, Bingi, Thrilok Chander, Borse, Rohidas, Buch, Vyom, Chand, Dipti, Chandwani, Ashish, Charan, Jaykaran, Chaudhari, Mayur, Chaudhari, Kirti, Chaudhary, Vipul, Chauhan, Nishant, Chikara, Gaurav, Daswani, Bharti, de Souza, Rosemarie, Desai, Chetna, Divakar, Balusamy, Divhare, Sujeet, Dorairajan, Suresh Kumar, Dutt, Naveen, Ethirajan, Therani Rajan, Gamit, Amit, Gamit, Sweta, Garg, Mahendra, Goenka, Ajay, Goenka, Aniket, Guleria, Randeep, Gupta, Paras, Gupta, Nivedita, Gupta, Madhur, Harde, Minal, Ingle, Vaibhav, Iyer, Shivkumar, Jamalapuram, Vaishnavi, Jayanthi, Rangarajan, Joshi, Rajnish, Kadam, Abhijeet, Kalakuntla, Hemanth, Kalikar, Mrunalini, Kalme, Sayali, Kamble, Suchit, Kant, Ravi, Kantharia, Bansari, Kashikar, Arundhati, Kavishvar, Abhay, Kayina, Choro Athipro, Kerkar, Pranali, Khadanga, Sagar, Khandare, Sagar, Kokate, Pranjali, Komathi, Jayavelu, Krishnan, Vijay, Krishnan, Jayasree, Krishnan, Sumitra, Kulur Mukhyaprana, Sudha, Kumarasamy, N, Mahavar, Sunil, Maitra, Souvik, Majumdar, Falguni, Malhotra, Supriya, Mamulwar, Megha, Malini, Padma, Marwah, Vikas, Maurya, Akhilesh, Mehta, Kedar, Mesipogu, Rajarao, Misra, Shobha, Mitra, Sajal, Mittal, Ankit, Mohan, Bharathi, Momin, Mohmmedirfan, Nag, Vijaya, Nagarajan, Ramakrishnan, Nagmani, Kammili, Narlawar, Uday, Natarajan, Gopalakrishnan, Nischal, Neeraj, Ogale, Dhananjay, Palat, Paltial, Panda, Prasan, Panda, Samiran, Pandya, Amee, Parate, Rohit, Paritekar, Arunita, Patel, Parvati, Patel, Chetna, Patel, Sunaina, Patel, Vitan, Patel, Deep, Patel, Harshad, Patil, Girish, Peter, Deepu, Prasad, Durga, Purohit, Vimlesh, Rabindrarajan, Ebenezer, Ranganathan, Lakshmiarasimhan, Rao, Tushara, Rao, Chakradhara, Rathod, Chirag, Raval, Devang, Ray, Avik, Reddy, Kamini, Rege, Sujata, Revathi, Ayyasamy, Roy, Dhara, Saigal, Saurabh, Sane, Suvarna, Sangale, Shashi, Seetharaman, Krishnamoorthy, Selvamuthu, Poongulali, Seshaiah, Kurada Venkata, Shadrach, Benhur, Shah, Jignesh, Shah, Sonal, Sharma, Swati, Sharma, Raman, Sharma, Shrikant, Singh, Krishna, Singh, Anil, Singh, Arjeet, Singhai, Abhishek, Soneja, Manish, Soni, Kapil Dev, Subhan, Thasneem banu, Subramaniam, Sudharshini, Sudarsanam, Thambu David, Sudarsi, Ravindra Kumar, Suleman, Dawood, Suthar, Nilay, Talati, Shriraj, Tambe, Murlidhar, Tejomurtula, Tilak, Tirupakuzhi Vijayaraghavan, Bharatkumar, Trikha, Anjan, Trivedi, Aarti, Udwadia, Zarir, Upadhyay, Kamlesh, Vasava, Ashwin, Vasudevan, Damodaran, Velayudham, Rajendran, Venkatasubramanian, Ramasubramanian, Verma, Mamta, Waghmare, Rakesh, Waikar, Anushka, Wig, Naveet, Afrilia, Annisa Rizky, Amin, Muhammad, Arlinda, Dona, Avrina, Rossa, Bang, Lois, Djaharuddin, Irawaty, Djojo, Aryan, Driyah, Sri Laning, Erastuti, Mila, Fajarwati, Tetra, Harsini, Harsini, Hartantri, Yovita, Herman, Deddy, Isbaniah, Fathiyah, Karyana, Muhammad, Kusuma, Indra, Mahmudji, Harli Amir, Medison, Irvan, Nugroho, Agung, Nurhayati, Nurhayati, Opitasari, Cicih, Pitoyo, Ceva Wicaksono, Pradana, Antonius Arditya, Raharjo, Sofyan Budi, Rahmaini, Ade, Risniati, Yenni, Riyanto, Bambang Sigit, Sajinadiyasa, I Gede Ketut, Sari, Flora Eka, Sitompul, Pompini Agustina, Soedarsono, Soedarsono, Somia, I Ketut Agus, Sugiri, Yani Jane, Sugiyono, Retna Indah, Susanto, Nugroho Harry, Syarif, Armaji Kamaludi, Yulianto, Aris, Afsharian, Mandana, Akhavi Mirab, Atefehsadat, Amini, Fatemeh, Amini, Mahnaz, Ansarin, Khalil, Baba Mahmoodi, Farhang, Baghaei, Parvaneh, Barazandeh, Fateme, Bayani, Masomeh, Dastan, Farzaneh, Ebrahimpour, Soheil, Eghtesad, Sareh, Fallahi, Mohammad Javad, Fallahpoor Golmaee, Fatemeh, Foroghi Ghomi, Seyed Yaser, Ghadir, Mohammad Reza, Gheitani, Mina, Ghiasvand, Fereshteh, Hafizi Lotfabadi, Saied, Hakamifard, Atousa, Hashemi Madani, Shima Sadat, Hormati, Ahmad, Hosseini, Hamed, Janbakhsh, Alireza, Javanian, Mostafa, Joukar, Farahnaz, Kamali, Alireza, Karampour, Amin, Khajavirad, Nasim, Khodabakhshi, Behnaz, Khodadadi, Javad, Khodashahi, Rozita, Kiani Majd, Somaieh, Mahfoozi, Lida, Mahmoodiyeh, Behnam, Mansour-Ghanaei, Fariborz, Mansouri, Feizollah, Mesgarpour, Bita, Mesri, Mehdi, Mikaeili, Haleh, Miladi, Ronak, Moghadami, Mohsen, Mohamadi, Payam, Mohraz, Minoo, Mohseni Afshar, Zeinab, Moogahi, Sasan, Mousavi Anari, Seyed Alireza, Mozaffar, Seyyed Hassan, Mozdourian, Mahnaz, Najafipour, Reza, Najari, Hamidreza, Nazemiyeh, Masoud, Norouzi, Alireza, Pourkazemi, Aydin, Poustchi, Hossein, Saberhosseini, Seyedeh Naeimeh, Saberi, Marzieh, Saber-Moghaddam, Niloufar, Sadeghi, Anahita, Sadeghi Haddad Zavareh, Mahmoud, Sahraian, Mohammad Ali, Salahi, Mehrdad, Salehi, Mohammad Reza, Sarmadian, Hossein, Sayad, Babak, Shirani, Kiana, Shirvani, Maria, Shojaei, Daryanaz, Shokri, Mehran, Siami, Zeinab, Sima, Ali Reza, Soleimani, Alireza, Soltanmohammad, Saedeh, Tabarsi, Payam, Taghizadieh, Ali, Tavassoli, Samaneh, Varnasseri, Mehran, Vaziri, Siavash, Yadyad, Mohammad Jaafar, Yaghoubi, Shoeleh, Yazdanpanah, Yalda, Yousefi, Farid, Zamanian, Mohammad Hossein, Zand, Farid, Zare Hoseinzade, Elham, Bergin, Colm, Cotter, Aoife, de Barra, Eoghan, Jackson, Arthur, Laffey, John, McCarthy, Cormac, Muldoon, Eavan, Sadlier, Corinna, Maguire, Teresa, Angheben, Andrea, Bai, Francesca, Bandera, Alessandra, Barchiesi, Francesco, Bassetti, Matteo, Bisi, Luca, Bonfanti, Paolo, Calò, Federica, Campoli, Caterina, Canovari, Benedetta, Capetti, Amedeo, Castelli, Francesco, Cauda, Roberto, Cingolani, Antonella, Cocco, Nicolò, Coppola, Nicola, Corcione, Silvia, Cremonini, Eleonora, d'Arminio Monforte, Antonella, de Gaetano Donati, Katleen, De Nardo, Pasquale, De Rosa, Francesco Giuseppe, Degioanni, Maria, Della Siega, Paola, Di Bella, Stefano, Drera, Bruno, Focà, Emanuele, Fornabaio, Chiara, Galli, Massimo, Giacomazzi, Donatella, Gori, Andrea, Gustinetti, Giulia, Iannuzzi, Francesca, Kertusha, Blerta, Lamonica, Silvia, Lichtner, Miriam, Lupia, Tommaso, Luzzati, Roberto, Macera, Margherita, Menatti, Elisabetta, Merelli, Maria, Merlini, Esther, Monari, Caterina, Pan, Angelo, Pecori, Davide, Pezzani, Diletta, Riccardi, Niccolò, Rodari, Paola, Roldan, Eugenia, Rovere, Pierangelo, Rusconi, Stefano, Scabini, Silvia, Tascini, Carlo, Viale, Pierluigi, Vincenzi, Marcello, Zuccalà, Paola, Zucchi, Patrizia, Al-Roomi, Moudhi, Al-Sabah, Salman, Schrapp, Kelly, Hassoun, Mahmoud, Matar, Madonna, Dbouni, Oussaima, Yared, Nadine, Saliba, Michele, Farra, Anna, Riachi, Moussa, Zablockiene, Birute, Reuter, Jean, Staub, Therese, Ab Wahab, Suhaila, Chew, Chun Keat, Chua, Hock Hin, Goh, Pik Pin, Lee, Heng Gee, Leong, Chee Loon, Low, Lee Lee, Mak, Wen Yao, Mohamed Gani, Yasmin, Muhamad, Dzawani, Zaidan, Nor Zaila, Ducker, Camilla, Demiri, Ilir, Aballi, Saad, Berg, Åse, Blomberg, Bjørn, Dalgard, Olav, Dyrhol-Riise, Anne Ma, Eiken, Ragnhild, Ernst, Gernot, Hannula, Ranula, Haugli, Metter, Heggelund, Lars, Hoel, Hedda, Hoff, Dag Arne Lihaug, Holten, Aleksander Rygh, Johannessen, Asgeir, Kåsine, Trine, Kildal, Anders Benjamin, Kittang, Bård Reikvam, Nezvalova-Henriksen, Katerina, Olsen, Inge Christoffer, Olsen, Roy Bjørkolt, Skei, Nina Vibeche, Skudal, Hilde, Tholin, Birgitte, Thoresen, Lars, Trøseid, Marius, Tveita, Anders, Vinge, Leif, Ystrøm, Carl Magnus, Al Jahdhami, Issa, AlNaamani, Khalid, Al Balushi, Zakariya, Pandak, Nenad, Abbas, Salma, Akhtar, Nasim, Azam, Sumeyya, Begum, Dilshad, Hassan, Sadia, Herekar, Fivzia, Khan, Shahzaib, Khan, Ejaz Ahmed, Mahmood, Syed Faisal, Nasir, Nosheen, Rahim, Anum, Sarfaraz, Samreen, Shaikh, Qurat-ul-Ain, Sultan, Faisal, Walayat, Usman, Agurto-Lescano, Erika Cecilia, Alcantara-Díaz, Andrés Martín, Alva-Correa, Ana María, Alvarado-Moreno, José Gustavo, Ángeles-Padilla, Bethsabé, Arbañil-Huamàn, Hugo César, Ávila-Reyes, Pool Christopher, Azañero-Haro, Johan Alexander, Barreto-Rocchetti, Luis Guillermo, Benitez-Peche, Jorge Marko A., Bernal-Màlaga, Karla Hortencia, Cabrera-Portillo, Liliana Norma, Carazas-Chavarry, Reynaldo Javier, Càrcamo, Paloma Mariana, Casimiro-Porras, Indira Catalina, Castillo-Espinoza, Jhuliana, Chacaltana-Huarcaya, Jesús Norberto, Cornejo-Valdivia, Carla Raquel, Cruz-Chereque, Augusto, Del-Aguila-Torres, Keith Cayetano Marcelino, Díaz-Chipana, Erika, Flores-Valdez, Neil, Franco-Vàsquez, Rosanna Andrea, Gallegos-López, Roxana Consuelo, Gastiaburú-Rodriguez, Dauma Yesenia, Gianella-Malca, Gonzalo Ernesto, Gomero-Lopez, Andrés Alonso, Hercilla-Vàsquez, Luis Enrique, Hueda-Zavaleta, Miguel Ángel, Ibarcena-Llerena, Claudia Vanessa, Iberico-Barrera, Carlos Alberto, Inquilla-Castillo, Miguel Angel, Juàrez-Eyzaguirre, Jesus Alberto, Laca-Barrera, Manuel, León-Jiménez, Franco, Luna-Wilson, Carla Vanessa, Màlaga, German, Marin, Ricardo, Mejía-Cordero, Fernando, Mendoza-Laredo, Juan Arturo, Meregildo-Rodríguez, Edinson Dante, Miranda-Manrique, Gonzalo Francisco, Olivera-Chaupis, Marco, Ortega-Monasterios, Fatima Josefina, Otazú-Ybàñez, Jimmy Pedro, Paredes-Moreno, María Angélica, Peña-Mayorga, Claudia Ximena, Peña-Vàsquez, Olivia del Carmen, Peña-Villalobos, Alejandro, Ponce, Oscar J, Ponte-Fernandez, Katherin Estefania, Pro, Jose, Quispe-Nolazco, César Miguel, Ramos-Samanez, Manuel Efrain, Rojas-Murrugarra, Kory Mirtha, Samanez-Pérez, Jorge Mauro, Sànchez-Carrillo, Halbert Chrostian, Sànchez-Garavito, Epifanio, Sànchez-Sevillano, Ricardo Manuel, Sandoval-Manrique, Hernan, Santos-Revilla, Gabriela, Silva-Ramos, Julio Antonio, Solano-Ico, Manuel Alberto, Soto, Alonso, Sotomayor-Woolcott, Giannilu Michelle, Tapia-Orihuela, Ruben Kevin Arnold, Terrazas-Obregón, Carmen Sara, Terrones-Levano, Victor Francisco, Ticona-Huaroto, Cesar Eduardo, Torres-Ninapayta, Walter, Torres-Ruiz, Oscar Martin, Ugarte-Mercado, Dario, Vargas-Anahua, Orlando José, Vàsquez-Becerra, Ruben Dario, Vàsquez-Cerro, José Gabriel, Villegas-Chiroque, Miguel, Williams, Anna Larson, Yauri-Lazo, Randi Mauricio, Abad, Cybele Lara, Andales-Bacolcol, Silverose Ann, Arcegono, Marlon, Arches, Jamie, Astudillo, Mary Grace, Aventura, Emily, Awing, Arlyn, Bala, Mishelle Vonnabie, Bello, Jia An, Blanco, Peter, Benedicto, Jubert, Buno, Susana, Cabrera, Justine, Cajulao, Thea Pamela, Caoili, Janice, Casiple-Amsua, Lina, Catambing, Victor, Chin, Inofel, Chua, Ma. Bernadette, Chua, Mitzi Marie, Climacosa, Fresthel Monica, David-Wang, Aileen, De los Reyes, Virginia, Europa, Gilly May, Fernandez, Lenora, Francisco, Jorge, Garcia, Gerard, Garcia, Jemelyn, Gler, Maria Tarcela, Isidro, Marie Grace Dawn, Javier, Rozelle Jade, Kwek, Marion, Lansang, Mary Ann, Lee, Aileen, Li, Kingbherly, Llanes, Mark Ramon Victor, Llorin, Ryan, Macadato, Omar Khayyam, Malundo, Anna Flor, Mercado, Maria Elizabeth, Mujeres, Mercedes, Nepomuceno, Marisse, Ngo-Sanchez, Katha, Orden, Mary Claire, Pablo-Villamor, Maria Philina, Paez, Ruel Dionisio, Palmes, Patricio, Panaligan, Marion, Quinivista-Yoon, Jenny Mae, Ramos, Mary Shiela Ariola, Ramos -Penalosa, Christine, Reyes, Sheila Marie, Roa, Kathryn, Roman, Arthur Dessi, Rosario, Minette Claire, Roxas, Evalyn, Santos, Lourdes Ella Gonzales, Soldevilla, Helmar, Solante, Rontgene, Suaco, Jane, Tagarda, Daisy, Tang, Issa Rufina, Te, Bob, Teo, Dennis, Tibayan, Christopher John, Villalobos, Ralph Elvi, Ymbong, Duane Richard, Zabat, Gelza Mae, Climacosa, Fresthel Monica, Mercado, Maria Elizabeth, Pablo-Villamor, Maria Philina, Batkova, Stepanka, Cardoso, Orlando, Garrote, Ana-Raquel, Lino, Sara, Manata, Maria-José, Pinheiro, Helder, Póvoas, Diana, Ramirez, Freddy, Seixas, Diana, Naji, Assem, Al Gethamy, M Al, AL-Mulaify, Mohammed Sami, Al Maghraby, Reem, Alrajhi, A, Al Sharidi, Aynaa, Alotaibi, Naif, AlShaharani, F, Barry, Mazin, Ghonem, Leen, Khalel, Anas, Kharaba, Ayman Mohammed, Alabdan, Lulwah, AlAbdullah, Mohammed Sharaf, Al Shabib, Abdullah, Bengu, Simangele, Bennet, Jacklyn, Dubula, Thozama, Howell, Pauline, Janse van Vuuren, Cloete, Kalla, Ismail, Lifson, Aimee, Maasdorp, Shaun, Magua, Nombulelo, Maluleke, Vongani, Mbhele, Nokuphiwa, Mdladla, Nathi, Mendelson, Mark, Menezes, Colin, Mwelase, Thando, Nchabeleng, Maphoshane, Palanee-Phillips, Thesla, Parker, Victoria, Rassool, Mohammed, Reeder, Paul, Sossen, Bianca, Steyn, Dewald, Tsitsi, Merika, van Blydenstein, Sarah Alex, Venter, Michelle, Van Vuuren, Janse, Venturas, Jacquie, Abad Pérez, Daniel, Abenza, Maria José, Alarcón-Payer, Carolina, Armero Garrigos, Eva, Arribas, Jose Ramon, Ascaso, Ana, Berenguer, Juan, Cabello-Clotet, Noemí, Chamorro Tojeiro, Sandra, Cuenca-Acevedo, Rafael, de la Calle, Fernando, Del Toro, Maria Dolores, Díaz Pollàn, Beatriz, Diez, Cristina, Esquillor-Rodrigo, María José, Estrada, Vicente, Fanciulli, Chiara, Fanjul, Francisco, Fernàndez de Orueta, Lucía, Ferre, Adrian, Ferreira Pasos, Eva Maria, Gainzarain-Arana, Juan-Carlos, Garcia, Felipe, García Deltoro, Miguel, Goikoetxea Agirre, Ane Josune, Gómez Barquero, Julia, Gomez-Huelgas, Ricardo, Gonzàlez Moraleja, Julio, Guijarro, Carlos, Gutierrez, Felix, Guzmàn, Jesús, Ibarguren, Maialen, Iribarren, Jose Antonio, Jerusalem, Koen, Juan Arribas, Arturo, Lalueza, A, Leone, Antonio, Lopez Azkarreta, Iñigo, Lozano-Martin, Daniel, Lucendo, Alfredo J, Luengo López, Mariella, Martín Oterino, JA, Masa, JF, Merino, Esperanza, Monge-Maillo, Begoña, Moran-Rodríguez, Miguel-Angel, Muñez Rubio, Elena, Muñoz Sanchez, Josefa, Nuñez Orantos, Maria Jose, Nuño, Enrique, Ortiz-De-Zarate-Ibarra, Zuriñe, Pagàn-Muñoz, Bàrbara, Paño-Pardo, José Ramón, Peñaranda, Maria, Pérez Chica, Gerardo, Pérez Fernàndez, AM, Pérez-López, Carmen, Polo San Ricardo, Victor, Portu-Zapirain, Joseba, Puchades, Francesco, Rivas Paterna, Ana Belen, Rodríguez Vidigal, Francisco F, Rodríguez-Baño, Jesus, Ruiz-Seco, Pilar, Ryan, Pablo, Saez-De-Adana, Ester, Salas, Rosario, Salavert Lletí, Miguel, Sandoval, Raquel, Toyas-Miazza, Carla, Valencia, Jorge, Vargas, Emilio, Velasco, Maria, Von Wichmann, Miguel Angel, Bosshard, Andreas, Calmy, Alexandra, Castro, Tiago, Cavassini, Matthias, Clerc, Olivier, Conen, Anna, Desbaillets, Nicolas, Desgranges, Florian, Duss, Francois, Emonet, Stephane, Erard, Veronique, Eyer, Myriam, Fayet-Mello, Aurélie, Flammer, Yvonne, Friedl, Andrée, Fulchini, Rosamaria, Furrer, Hansjakob, Garin, Nicolas, Gastberger, Salome, Greiner, Michael, Haefliger, David, Haubitz, Sebastian, Hoffmann, Matthias, Isenring, Egon, Jakopp, Barbara, Lampert, Markus, Marinosci, Annalisa, Martin, Yvonne, Petignat, Pierre-Auguste, Piso, Rein Jan, Prendki, Virginie, Rutishauser, Jonas, Schaefer, Elisabeth, Schmiedel, Yvonne, Schwery, Stefan, Stavropoulou, Elisavet, Stoeckle, Marcel, Suttels, Veronique, Thurnher, Maria Christine, van den Bogaart, Lorena, West, Emily, Wiegand, Jan, Wiggli, Benedikt·2022·The Lancet
DOI 10.1016/s0140-6736(22)00519-0
Open this paper in CoChat — free account

Abstract

BACKGROUND: The Solidarity trial among COVID-19 inpatients has previously reported interim mortality analyses for four repurposed antiviral drugs. Lopinavir, hydroxychloroquine, and interferon (IFN)-β1a were discontinued for futility but randomisation to remdesivir continued. Here, we report the final results of Solidarity and meta-analyses of mortality in all relevant trials to date. METHODS: Solidarity enrolled consenting adults (aged ≥18 years) recently hospitalised with, in the view of their doctor, definite COVID-19 and no contraindication to any of the study drugs, regardless of any other patient characteristics. Participants were randomly allocated, in equal proportions between the locally available options, to receive whichever of the four study drugs (lopinavir, hydroxychloroquine, IFN-β1a, or remdesivir) were locally available at that time or no study drug (controls). All patients also received the local standard of care. No placebos were given. The protocol-specified primary endpoint was in-hospital mortality, subdivided by disease severity. Secondary endpoints were progression to ventilation if not already ventilated, and time-to-discharge from hospital. Final log-rank and Kaplan-Meier analyses are presented for remdesivir, and are appended for all four study drugs. Meta-analyses give weighted averages of the mortality findings in this and all other randomised trials of these drugs among hospital inpatients. Solidarity is registered with ISRCTN, ISRCTN83971151, and ClinicalTrials.gov, NCT04315948. FINDINGS: Between March 22, 2020, and Jan 29, 2021, 14 304 potentially eligible patients were recruited from 454 hospitals in 35 countries in all six WHO regions. After the exclusion of 83 (0·6%) patients with a refuted COVID-19 diagnosis or encrypted consent not entered into the database, Solidarity enrolled 14 221 patients, including 8275 randomly allocated (1:1) either to remdesivir (ten daily infusions, unless discharged earlier) or to its control (allocated no study drug although remdesivir was locally available). Compliance was high in both groups. Overall, 602 (14·5%) of 4146 patients assigned to remdesivir died versus 643 (15·6%) of 4129 assigned to control (mortality rate ratio [RR] 0·91 [95% CI 0·82-1·02], p=0·12). Of those already ventilated, 151 (42·1%) of 359 assigned to remdesivir died versus 134 (38·6%) of 347 assigned to control (RR 1·13 [0·89-1·42], p=0·32). Of those not ventilated but on oxygen, 14·6% assigned to remdesivir died versus 16·3% assigned to control (RR 0·87 [0·76-0·99], p=0·03). Of 1730 not on oxygen initially, 2·9% assigned to remdesivir died versus 3·8% assigned to control (RR 0·76 [0·46-1·28], p=0·30). Combining all those not ventilated initially, 11·9% assigned to remdesivir died versus 13·5% assigned to control (RR 0·86 [0·76-0·98], p=0·02) and 14·1% versus 15·7% progressed to ventilation (RR 0·88 [0·77-1·00], p=0·04). The non-prespecified composite outcome of death or progression to ventilation occurred in 19·6% assigned to remdesivir versus 22·5% assigned to control (RR 0·84 [0·75-0·93], p=0·001). Allocation to daily remdesivir infusions (vs open-label control) delayed discharge by about 1 day during the 10-day treatment period. A meta-analysis of mortality in all randomised trials of remdesivir versus no remdesivir yielded similar findings. INTERPRETATION: Remdesivir has no significant effect on patients with COVID-19 who are already being ventilated. Among other hospitalised patients, it has a small effect against death or progression to ventilation (or both). FUNDING: WHO.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/s0140-6736(22)00519-0

Cites

20 of 20 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 20 references

Cited by

See all 394

Metadata

Authors
Pan, H., Peto, R., Henao Restrepo, A. M., Preziosi, M.-P., Sathiyamoorthy, V., Karim, Q. A., Alejandria, M., Hernàndez García, C., Kieny, M.-P., Malekzadeh, R., Murthy, S., Reddy, K. S., Periago, M. R., Hanna, P. A., Abutidze, A., Ader, F., Al-Bader, A., Alhasawi, A., Allum, E., Al Mawali, A., Alotaibi, A., Alvarez- Moreno, C., Appadoo, S., Arts, D., Asiri, A., Aukrust, P., Barratt-Due, A., Genetu Bayih, A., Beaumont, H., Bellani, S., Benassi, V., Bhargava, B., Branca, M., Cappel-Porter, H., Cerrato, N., Cheick Haidara, F., Chow, T. S., Como, N., Eustace, J., Gabunia, T., García, P., Godbole, S., Gotuzzo, E., Griskevicius, L., Hamra, R., Hassan, M., Hassany, M., Hutton, D., Irmansyah, I., Jancoriene, L., Khamis, F., Kirwan, J., Kumar, S., Lennon, P., Lopardo, G., Lydon, P., Magrini, N., Manevska, S., Manuel, O., McGinty, S., Medina, M., Mesa Rubio, M. L., Miranda Montoya, M. C., Nel, J., Nunes, E., Perola, M., Portoles, A., Rasmin, M., Raza, A., Rees, H., Reges, P., Rogers, C., Salami, K., Salvadori, M., Sauermann, M., Sinani, N., Sow, S., Sterne, J. A., Stevanovikj, M., Tacconelli, E., Tavares Maltez, F. M., Teferi, M., Tikkinen, K., Trelle, S., Tsertsvadze, T., Zaid, H., Røttingen, J.-A., Swaminathan, S., Ryan, M., Gjermeni, N., Meta, E., Aguila, D., Alonso, I., Altamirano, M., Alvarez, M., Alzola, R., Arce, V., Arribillaga, P., Avila, R., Balbuena, J., Barcelona, L., Barletta, J., Benedetti, M., Berdiñas, V., Burgui, J., Caimi, S., Carrillo, J., Carrizo, J., Castelli, J., Cazaux, A., Cervellino, F., Chalco, A., Chediack, V., Cunto, E., D'Amico, N., de Vedia, L., Delgado, C., Di Pilla, D., Díaz, M., Díaz Aguiar, P., Domínguez, C., Ellero, L., Farina, J., Fernàndez, J., Ferreyra, R., Filippi, M., Fogar, C., Frare, P., Giudiche, C., Golikow, M., Gomez, M. G., Hermida, L., Hurtado, M., Jacobo, M., Jaume, M., Laplume, D., Lescano, M., Lista, N., Loiacono, F., López, A. B., Losso, M., Luna, C., Lupo, S., Marianelli, L., Martin, A., Masciottra, F., Mykietiuk, A., Orellano, L., Pachioli, V., Padilla, M. J., Pallavicini, C., Patroso, J., Perez Blanco, L., Presas, J. L., Provenzano, M., Lavera, L., Reichert, V., Riveros, F., Rodríguez, A., Rolon, M. J., Salvay, C., Simonetta, M., Sisto, A., Themines, S., Tito, F., Toibaro, J., Torales, G., Verón, L., Vizzotti, C., Egle, A., Greil, R., Joannidis, M., Altdorfer, A., Belkhir, L., Fraipont, V., Hites, M., Arruda, E., Breda, G., Colussi, A., Corradi, M., Croda, J., Duani, H., João, E., Machado, E., Mello, F., Miranda Filho, D., Monteiro, P., Nunes, C., Pereira Junior, L. C., Pinto, G., Raboni, S., Ramos, M., Ruffing, L., Santos, V., Souza, T., Medeiros, M., Schwarzbold, A., Ali, K., Azher, T., Bellemare, D., Binnie, A., Borgia, S., Cavayas, Y. A., Chagnon, N., Cheng, M., Cloutier, E., Conly, J., Costiniuk, C., Daneman, N., Douglas, J., Downey, C., Duan, E., Durand, M., English, S., Farjou, G., Fera, E., Fontela, P., Fowler, R., Fralick, M., Gamble, D. G., Geagea, A., Grant, J., Harrison, L., Havey, T., Hoang, H., Kelly, L., Keynan, Y., Khwaja, K., Klein, M., Kolan, C., Kronfli, N., Lamontagne, F., Lee, N., Lee, T., Lim, R., Lostun, A., MacIntyre, E., Malhamé, I., Martin-Carrier, F., McGuinty, M., Munan, M., O'Neil, C., Ovakim, D., Papenburg, J., Parhar, K., Parvathy, S., Perez-Patrigeon, S., Rishu, A., Rushton, M., Scherr, K., Schwartz, K., Semret, M., Silverman, M., Singh, A., Sligl, W., Smith, S., Somayaji, R., Tan, D., Tran, T.-V., Tremblay, A., Tsang, J., Turgeon, A., Vakil, E., Weatherald, J., Yansouni, C., Zarychanski, R., Aristizabal, C., Bravo, J., Caicedo, M., Chacón, J., Garzón, D., Guevara, F., Lozano-Gonzàlez, S., Macareno, H., Montañez-Ayala, A., Oñate, J., Rojas-Gambasica, J., Rosso, F., Saavedra, C., Valderrama, S., Vàquiro-Herrera, E., Varón-Vega, F., Zuluaga, I., Abdel Baki, A., Abdelbary, A., Abdel-Razek, W., Amin, W., Asem, N., Elassal, G., Elshesheny, M., Fathy, M., Fathy, N., Fayed, N., Hammam, A., Hassany, S., Ibrahim, H., Kamal, E., Masoud, H., Mohamed, M., Mohamed Gouda, A., Moustafa, E., Okasha, S., Rafik, A., Said, A., Sedky, A., Solyman Kabil, M., Tarek, S., Tharwat, A., Zaky, S., Abegaz, E. T., Bekele, Z. M., Asfaw, F. M., Tegegne, N. A., Teklemariam, M. F., Nigusse, F. T., Achalu, D. L., Weldegergs, S. T., Huluka, D. K., Tereda, A. B., Ala-Kokko, T., Delany, J., Ekroos, H., Hankkio, R., Haukipää, M., Hetemäki, I., Holma, P., Holmberg, V., Horstia, S., Jalkanen, V., Jämsänen, T., Järventie, J., Järvinen, P., Kalliala, I., Kauma, H., Kilpeläinen, T., Kreivi, H.-R., Kuitunen, I., Lamminmäki, S., Mäkinen, L., Mäntylä, J., Mattila, T., Myllärniemi, M., Niskanen, J., Nykänen, T., Nyqvist, M., Paajanen, J., Partanen, T., Patovirta, R.-L., Paukkeri, E.-L., Puusti, E., Renner, A., Reponen, E., Risku, S., Rosberg, T., Rutanen, J., Säilä, P., Salonen, P., Sinisalo, M., Sivenius, K., Tuominen, S., Aboab, J., Alfaiate, T., Andrejak, C., Andreu, P., Belhadi, D., Benezit, F., Botelho-Nevers, E., Bouadma, L., Bougon, D., Bouiller, K., Bounes, F., Boyer, A., Bruel, C., Buffet, A., Burdet, C., Cazanave, C., Chabertier, C., Clere-Jehl, R., Costagliola, D., Courjon, J.-V., Crockett, F., Danion, F., Dechanet, A., Dellamonica, J., Delmas, C., Diallo, A., Djossou, F., Dubost, C., Dupont, A., Epaulard, O., Faure, E., Faure, K., Fayol, A., Figueiredo, S., Fougerou, C., Gaborit, B., Gaci, R., Gagneux-Brunon, A., Gallien, S., Garot, D., Goehringer, F., Gruson, D., Hinschberger, O., Hulot, J.-S., Jaureguiberry, S., Jean-Michel, V., Kerneis, S., Kimmoun, A., Klouche, K., Lachatre, M., Lacombe, K., Laine, F., Lanoix, J. P., Laribi, S., Launay, O., Laviolle, B., Le Moing, V., Le Pavec, J., Lebeaux, D., Leroy, S., Lescure, X., Livrozet, M., Makinson, A., Malvy, D., Marquette, C.-H., Martin-Blondel, G., Mayaux, J., Mekontso Dessap, A., Mentre, F., Mercier, N., Meziani, F., Molina, J. M., Mootien, Y., Mourvillier, B., Navellou, J. C., Noret, M., Peiffer- Smadja, N., Peytavin, G., Pialoux, G., Pilmis, B., Piroth, L., Poindron, V., Poissy, J., Pourcher, V., Quenot, J. P., Raffi, F., Reignier, J., Richard, J. C., Robert, C., Saillard, J., Sayre, N., Senneville, E., Stefan, F., Tellier, M. C., Terzi, N., Textoris, J., Thiery, G., Timsit, J. F., Tolsma, V., Tubiana, S., Wallet, F., Yazdanpanah, Y., Zerbib, Y., Aguilar, C., Erazo, L., Fiallos, A., Figueroa, R., Flores, J. J., Melendez, L., Moncada, W., Abraham, O. C., Acharya, C., Aedula, V. S., Aggarwal, R., Agrawal, N., Agrawal, U., Agrawal, A., Ahmad, M., Atal, S., Babu, A., Baidya, D. K., Balachandran, A., Bangar, R., Bhadade, R., Bhandari, S., Bhapal, M., Bhardwaj, P., Bhati, G., Bhatia, P., Bhatt, K., Bingi, T. C., Borse, R., Buch, V., Chand, D., Chandwani, A., Charan, J., Chaudhari, M., Chaudhari, K., Chaudhary, V., Chauhan, N., Chikara, G., Daswani, B., de Souza, R., Desai, C., Divakar, B., Divhare, S., Dorairajan, S. K., Dutt, N., Ethirajan, T. R., Gamit, A., Gamit, S., Garg, M., Goenka, A., Goenka, A., Guleria, R., Gupta, P., Gupta, N., Gupta, M., Harde, M., Ingle, V., Iyer, S., Jamalapuram, V., Jayanthi, R., Joshi, R., Kadam, A., Kalakuntla, H., Kalikar, M., Kalme, S., Kamble, S., Kant, R., Kantharia, B., Kashikar, A., Kavishvar, A., Kayina, C. A., Kerkar, P., Khadanga, S., Khandare, S., Kokate, P., Komathi, J., Krishnan, V., Krishnan, J., Krishnan, S., Kulur Mukhyaprana, S., Kumarasamy, N., Mahavar, S., Maitra, S., Majumdar, F., Malhotra, S., Mamulwar, M., Malini, P., Marwah, V., Maurya, A., Mehta, K., Mesipogu, R., Misra, S., Mitra, S., Mittal, A., Mohan, B., Momin, M., Nag, V., Nagarajan, R., Nagmani, K., Narlawar, U., Natarajan, G., Nischal, N., Ogale, D., Palat, P., Panda, P., Panda, S., Pandya, A., Parate, R., Paritekar, A., Patel, P., Patel, C., Patel, S., Patel, V., Patel, D., Patel, H., Patil, G., Peter, D., Prasad, D., Purohit, V., Rabindrarajan, E., Ranganathan, L., Rao, T., Rao, C., Rathod, C., Raval, D., Ray, A., Reddy, K., Rege, S., Revathi, A., Roy, D., Saigal, S., Sane, S., Sangale, S., Seetharaman, K., Selvamuthu, P., Seshaiah, K. V., Shadrach, B., Shah, J., Shah, S., Sharma, S., Sharma, R., Sharma, S., Singh, K., Singh, A., Singh, A., Singhai, A., Soneja, M., Soni, K. D., Subhan, T. B., Subramaniam, S., Sudarsanam, T. D., Sudarsi, R. K., Suleman, D., Suthar, N., Talati, S., Tambe, M., Tejomurtula, T., Tirupakuzhi Vijayaraghavan, B., Trikha, A., Trivedi, A., Udwadia, Z., Upadhyay, K., Vasava, A., Vasudevan, D., Velayudham, R., Venkatasubramanian, R., Verma, M., Waghmare, R., Waikar, A., Wig, N., Afrilia, A. R., Amin, M., Arlinda, D., Avrina, R., Bang, L., Djaharuddin, I., Djojo, A., Driyah, S. L., Erastuti, M., Fajarwati, T., Harsini, H., Hartantri, Y., Herman, D., Isbaniah, F., Karyana, M., Kusuma, I., Mahmudji, H. A., Medison, I., Nugroho, A., Nurhayati, N., Opitasari, C., Pitoyo, C. W., Pradana, A. A., Raharjo, S. B., Rahmaini, A., Risniati, Y., Riyanto, B. S., Sajinadiyasa, I. G. K., Sari, F. E., Sitompul, P. A., Soedarsono, S., Somia, I. K. A., Sugiri, Y. J., Sugiyono, R. I., Susanto, N. H., Syarif, A. K., Yulianto, A., Afsharian, M., Akhavi Mirab, A., Amini, F., Amini, M., Ansarin, K., Baba Mahmoodi, F., Baghaei, P., Barazandeh, F., Bayani, M., Dastan, F., Ebrahimpour, S., Eghtesad, S., Fallahi, M. J., Fallahpoor Golmaee, F., Foroghi Ghomi, S. Y., Ghadir, M. R., Gheitani, M., Ghiasvand, F., Hafizi Lotfabadi, S., Hakamifard, A., Hashemi Madani, S. S., Hormati, A., Hosseini, H., Janbakhsh, A., Javanian, M., Joukar, F., Kamali, A., Karampour, A., Khajavirad, N., Khodabakhshi, B., Khodadadi, J., Khodashahi, R., Kiani Majd, S., Mahfoozi, L., Mahmoodiyeh, B., Mansour-Ghanaei, F., Mansouri, F., Mesgarpour, B., Mesri, M., Mikaeili, H., Miladi, R., Moghadami, M., Mohamadi, P., Mohraz, M., Mohseni Afshar, Z., Moogahi, S., Mousavi Anari, S. A., Mozaffar, S. H., Mozdourian, M., Najafipour, R., Najari, H., Nazemiyeh, M., Norouzi, A., Pourkazemi, A., Poustchi, H., Saberhosseini, S. N., Saberi, M., Saber-Moghaddam, N., Sadeghi, A., Sadeghi Haddad Zavareh, M., Sahraian, M. A., Salahi, M., Salehi, M. R., Sarmadian, H., Sayad, B., Shirani, K., Shirvani, M., Shojaei, D., Shokri, M., Siami, Z., Sima, A. R., Soleimani, A., Soltanmohammad, S., Tabarsi, P., Taghizadieh, A., Tavassoli, S., Varnasseri, M., Vaziri, S., Yadyad, M. J., Yaghoubi, S., Yazdanpanah, Y., Yousefi, F., Zamanian, M. H., Zand, F., Zare Hoseinzade, E., Bergin, C., Cotter, A., de Barra, E., Jackson, A., Laffey, J., McCarthy, C., Muldoon, E., Sadlier, C., Maguire, T., Angheben, A., Bai, F., Bandera, A., Barchiesi, F., Bassetti, M., Bisi, L., Bonfanti, P., Calò, F., Campoli, C., Canovari, B., Capetti, A., Castelli, F., Cauda, R., Cingolani, A., Cocco, N., Coppola, N., Corcione, S., Cremonini, E., d'Arminio Monforte, A., de Gaetano Donati, K., De Nardo, P., De Rosa, F. G., Degioanni, M., Della Siega, P., Di Bella, S., Drera, B., Focà, E., Fornabaio, C., Galli, M., Giacomazzi, D., Gori, A., Gustinetti, G., Iannuzzi, F., Kertusha, B., Lamonica, S., Lichtner, M., Lupia, T., Luzzati, R., Macera, M., Menatti, E., Merelli, M., Merlini, E., Monari, C., Pan, A., Pecori, D., Pezzani, D., Riccardi, N., Rodari, P., Roldan, E., Rovere, P., Rusconi, S., Scabini, S., Tascini, C., Viale, P., Vincenzi, M., Zuccalà, P., Zucchi, P., Al-Roomi, M., Al-Sabah, S., Schrapp, K., Hassoun, M., Matar, M., Dbouni, O., Yared, N., Saliba, M., Farra, A., Riachi, M., Zablockiene, B., Reuter, J., Staub, T., Ab Wahab, S., Chew, C. K., Chua, H. H., Goh, P. P., Lee, H. G., Leong, C. L., Low, L. L., Mak, W. Y., Mohamed Gani, Y., Muhamad, D., Zaidan, N. Z., Ducker, C., Demiri, I., Aballi, S., Berg, Å., Blomberg, B., Dalgard, O., Dyrhol-Riise, A. M., Eiken, R., Ernst, G., Hannula, R., Haugli, M., Heggelund, L., Hoel, H., Hoff, D. A. L., Holten, A. R., Johannessen, A., Kåsine, T., Kildal, A. B., Kittang, B. R., Nezvalova-Henriksen, K., Olsen, I. C., Olsen, R. B., Skei, N. V., Skudal, H., Tholin, B., Thoresen, L., Trøseid, M., Tveita, A., Vinge, L., Ystrøm, C. M., Al Jahdhami, I., AlNaamani, K., Al Balushi, Z., Pandak, N., Abbas, S., Akhtar, N., Azam, S., Begum, D., Hassan, S., Herekar, F., Khan, S., Khan, E. A., Mahmood, S. F., Nasir, N., Rahim, A., Sarfaraz, S., Shaikh, Q.-U.-A., Sultan, F., Walayat, U., Agurto-Lescano, E. C., Alcantara-Díaz, A. M., Alva-Correa, A. M., Alvarado-Moreno, J. G., Ángeles-Padilla, B., Arbañil-Huamàn, H. C., Ávila-Reyes, P. C., Azañero-Haro, J. A., Barreto-Rocchetti, L. G., Benitez-Peche, J. M. A., Bernal-Màlaga, K. H., Cabrera-Portillo, L. N., Carazas-Chavarry, R. J., Càrcamo, P. M., Casimiro-Porras, I. C., Castillo-Espinoza, J., Chacaltana-Huarcaya, J. N., Cornejo-Valdivia, C. R., Cruz-Chereque, A., Del-Aguila-Torres, K. C. M., Díaz-Chipana, E., Flores-Valdez, N., Franco-Vàsquez, R. A., Gallegos-López, R. C., Gastiaburú-Rodriguez, D. Y., Gianella-Malca, G. E., Gomero-Lopez, A. A., Hercilla-Vàsquez, L. E., Hueda-Zavaleta, M. Á., Ibarcena-Llerena, C. V., Iberico-Barrera, C. A., Inquilla-Castillo, M. A., Juàrez-Eyzaguirre, J. A., Laca-Barrera, M., León-Jiménez, F., Luna-Wilson, C. V., Màlaga, G., Marin, R., Mejía-Cordero, F., Mendoza-Laredo, J. A., Meregildo-Rodríguez, E. D., Miranda-Manrique, G. F., Olivera-Chaupis, M., Ortega-Monasterios, F. J., Otazú-Ybàñez, J. P., Paredes-Moreno, M. A., Peña-Mayorga, C. X., Peña-Vàsquez, O. D. C., Peña-Villalobos, A., Ponce, O. J., Ponte-Fernandez, K. E., Pro, J., Quispe-Nolazco, C. M., Ramos-Samanez, M. E., Rojas-Murrugarra, K. M., Samanez-Pérez, J. M., Sànchez-Carrillo, H. C., Sànchez-Garavito, E., Sànchez-Sevillano, R. M., Sandoval-Manrique, H., Santos-Revilla, G., Silva-Ramos, J. A., Solano-Ico, M. A., Soto, A., Sotomayor-Woolcott, G. M., Tapia-Orihuela, R. K. A., Terrazas-Obregón, C. S., Terrones-Levano, V. F., Ticona-Huaroto, C. E., Torres-Ninapayta, W., Torres-Ruiz, O. M., Ugarte-Mercado, D., Vargas-Anahua, O. J., Vàsquez-Becerra, R. D., Vàsquez-Cerro, J. G., Villegas-Chiroque, M., Williams, A. L., Yauri-Lazo, R. M., Abad, C. L., Andales-Bacolcol, S. A., Arcegono, M., Arches, J., Astudillo, M. G., Aventura, E., Awing, A., Bala, M. V., Bello, J. A., Blanco, P., Benedicto, J., Buno, S., Cabrera, J., Cajulao, T. P., Caoili, J., Casiple-Amsua, L., Catambing, V., Chin, I., Chua, M. B., Chua, M. M., Climacosa, F. M., David-Wang, A., De los Reyes, V., Europa, G. M., Fernandez, L., Francisco, J., Garcia, G., Garcia, J., Gler, M. T., Isidro, M. G. D., Javier, R. J., Kwek, M., Lansang, M. A., Lee, A., Li, K., Llanes, M. R. V., Llorin, R., Macadato, O. K., Malundo, A. F., Mercado, M. E., Mujeres, M., Nepomuceno, M., Ngo-Sanchez, K., Orden, M. C., Pablo-Villamor, M. P., Paez, R. D., Palmes, P., Panaligan, M., Quinivista-Yoon, J. M., Ramos, M. S. A., Ramos -Penalosa, C., Reyes, S. M., Roa, K., Roman, A. D., Rosario, M. C., Roxas, E., Santos, L. E. G., Soldevilla, H., Solante, R., Suaco, J., Tagarda, D., Tang, I. R., Te, B., Teo, D., Tibayan, C. J., Villalobos, R. E., Ymbong, D. R., Zabat, G. M., Climacosa, F. M., Mercado, M. E., Pablo-Villamor, M. P., Batkova, S., Cardoso, O., Garrote, A.-R., Lino, S., Manata, M.-J., Pinheiro, H., Póvoas, D., Ramirez, F., Seixas, D., Naji, A., Al Gethamy, M. A., AL-Mulaify, M. S., Al Maghraby, R., Alrajhi, A., Al Sharidi, A., Alotaibi, N., AlShaharani, F., Barry, M., Ghonem, L., Khalel, A., Kharaba, A. M., Alabdan, L., AlAbdullah, M. S., Al Shabib, A., Bengu, S., Bennet, J., Dubula, T., Howell, P., Janse van Vuuren, C., Kalla, I., Lifson, A., Maasdorp, S., Magua, N., Maluleke, V., Mbhele, N., Mdladla, N., Mendelson, M., Menezes, C., Mwelase, T., Nchabeleng, M., Palanee-Phillips, T., Parker, V., Rassool, M., Reeder, P., Sossen, B., Steyn, D., Tsitsi, M., van Blydenstein, S. A., Venter, M., Van Vuuren, J., Venturas, J., Abad Pérez, D., Abenza, M. J., Alarcón-Payer, C., Armero Garrigos, E., Arribas, J. R., Ascaso, A., Berenguer, J., Cabello-Clotet, N., Chamorro Tojeiro, S., Cuenca-Acevedo, R., de la Calle, F., Del Toro, M. D., Díaz Pollàn, B., Diez, C., Esquillor-Rodrigo, M. J., Estrada, V., Fanciulli, C., Fanjul, F., Fernàndez de Orueta, L., Ferre, A., Ferreira Pasos, E. M., Gainzarain-Arana, J.-C., Garcia, F., García Deltoro, M., Goikoetxea Agirre, A. J., Gómez Barquero, J., Gomez-Huelgas, R., Gonzàlez Moraleja, J., Guijarro, C., Gutierrez, F., Guzmàn, J., Ibarguren, M., Iribarren, J. A., Jerusalem, K., Juan Arribas, A., Lalueza, A., Leone, A., Lopez Azkarreta, I., Lozano-Martin, D., Lucendo, A. J., Luengo López, M., Martín Oterino, J., Masa, J., Merino, E., Monge-Maillo, B., Moran-Rodríguez, M.-A., Muñez Rubio, E., Muñoz Sanchez, J., Nuñez Orantos, M. J., Nuño, E., Ortiz-De-Zarate-Ibarra, Z., Pagàn-Muñoz, B., Paño-Pardo, J. R., Peñaranda, M., Pérez Chica, G., Pérez Fernàndez, A., Pérez-López, C., Polo San Ricardo, V., Portu-Zapirain, J., Puchades, F., Rivas Paterna, A. B., Rodríguez Vidigal, F. F., Rodríguez-Baño, J., Ruiz-Seco, P., Ryan, P., Saez-De-Adana, E., Salas, R., Salavert Lletí, M., Sandoval, R., Toyas-Miazza, C., Valencia, J., Vargas, E., Velasco, M., Von Wichmann, M. A., Bosshard, A., Calmy, A., Castro, T., Cavassini, M., Clerc, O., Conen, A., Desbaillets, N., Desgranges, F., Duss, F., Emonet, S., Erard, V., Eyer, M., Fayet-Mello, A., Flammer, Y., Friedl, A., Fulchini, R., Furrer, H., Garin, N., Gastberger, S., Greiner, M., Haefliger, D., Haubitz, S., Hoffmann, M., Isenring, E., Jakopp, B., Lampert, M., Marinosci, A., Martin, Y., Petignat, P.-A., Piso, R. J., Prendki, V., Rutishauser, J., Schaefer, E., Schmiedel, Y., Schwery, S., Stavropoulou, E., Stoeckle, M., Suttels, V., Thurnher, M. C., van den Bogaart, L., West, E., Wiegand, J., & Wiggli, B.
Venue
The Lancet
Publisher
Elsevier BV
Published
2022-05
Volume
399
Issue
10339
Pages
1941-1953
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/s0140-6736(22)00519-0
OpenAlex
W4225313493
Cited by
394
References
20
FWCI
41.96
Type
journal article
Language
en
Open access
hybrid

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses. https://app.cochat.ai/papers/10.1016/s0140-6736(22)00519-0
The paper
Pan, H., Peto, R., Henao Restrepo, A. M., Preziosi, M.-P., Sathiyamoorthy, V., Karim, Q. A., Alejandria, M., Hernàndez García, C., Kieny, M.-P., Malekzadeh, R., Murthy, S., Reddy, K. S., Periago, M. R., Hanna, P. A., Abutidze, A., Ader, F., Al-Bader, A., Alhasawi, A., Allum, E., . . . Wiggli, B. (2022). Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses. The Lancet. https://doi.org/10.1016/s0140-6736(22)00519-0

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.