EFFECTS OF LOW-CARBOHYDRATE DIET AND DIABETES MELLITUS ON PLASMA CONCENTRATIONS OF GLUCOSE, NON-ESTERIFIED FATTY ACID, AND INSULIN DURING ORAL GLUCOSE-TOLERANCE TESTS
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The carbohydrate content of the diet for a few days before an oral glucose tolerance test markedly affects the result, with poorer glucose tolerance after a low-carbohydrate diet.
“It has long been known that the CHO content of the diet for the few days before an oral glucose tolerance test markedly affects the result, with poorer glucose tolerance being observed after a low-CHO diet (Hales & Randle, 1963).”
From Glycaemic index methodology (2005) · cites this paper as Hales & Randle, 1963
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Randle, P. J., Garland, P. B., Hales, C. N., & Newsholme, E. A. (1963) · The Lancet · doi:10.1016/s0140-6736(63)91500-9 · Cited by 5,093 · see citing works
Self-citationFranz, M. J., Bantle, J. P., Beebe, C. A., Brunzell, J. D., Chiasson, J.-L., Garg, A., Holzmeister, L. A., Hoogwerf, B., Mayer-Davis, E., Mooradian, A. D., et al. (2002) · Diabetes Care · doi:10.2337/diacare.25.1.148 · Cited by 1,165 · see citing works
Brouns, F., Bjorck, I., Frayn, K. N., Gibbs, A. L., Lang, V., Slama, G., & Wolever, T. M. S. (2005) · Nutrition Research Reviews · doi:10.1079/nrr2005100 · Cited by 1,061 · see citing works
Effect of fatty acids on glucose production and utilization in man.
Ferrannini, E., Barrett, E. J., Bevilacqua, S., & DeFronzo, R. A. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111133 · Cited by 1,050 · see citing works
Randle, P., Newsholme, E., & Garland, P. (1964) · Biochemical Journal · doi:10.1042/bj0930652 · Cited by 736 · see citing works
Self-citationAbnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids.
Schalch, D. S., & Kipnis, D. M. (1965) · Journal of Clinical Investigation · doi:10.1172/jci105308 · Cited by 210 · see citing works
Low-carbohydrate-diet score and risk of type 2 diabetes in women
Halton, T. L., Liu, S., Manson, J. E., & Hu, F. B. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.2.339 · Cited by 200 · see citing works
- Authors
- Hales, C. N., & Randle, P. J.
- Affiliations
- University of Cambridge (GB)
- Venue
- The Lancet
- Publisher
- Elsevier BV
- Published
- 1963-04
- Volume
- 281
- Issue
- 7285
- Pages
- 790-794
- ISSN
- 0099-5355 (ISSN-L)
- 0140-6736
- OpenAlex
- W1968008536
- Cited by
- 363
- References
- 0
- Citations by year
- 2023: 2 · 2022: 2 · 2020: 1 · 2019: 1 · 2018: 1 · 2015: 1 · 2014: 1
- FWCI
- 81.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Lancet (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Diet and metabolism studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- low-carbohydrate diet, diabetes mellitus, plasma glucose, free fatty acids, insulin, oral glucose tolerance test, insulin resistance
- MeSH terms
- Blood Glucose, Carbohydrates, Diabetes Mellitus, Fatty Acids, Glucose, Glucose Tolerance Test, Humans, Insulin, Sweetening Agents, Diet, Carbohydrate-Restricted
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