Cited by 736Metabolism, Diabetes, and CancerAdipose Tissue and MetabolismDiabetes Management and Research

Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles

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Randle, PJ, Newsholme, EA, Garland, PB·1964·Biochemical Journal

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Research Article| December 01 1964 Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles PJ Randle; PJ Randle Search for other works by this author on: This Site PubMed Google Scholar EA Newsholme; EA Newsholme Search for other works by this author on: This Site PubMed Google Scholar PB Garland PB Garland Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1964) 93 (3): 652–665. https://doi.org/10.1042/bj0930652 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation PJ Randle, EA Newsholme, PB Garland; Regulation of glucose uptake by muscle. 8. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles. Biochem J 1 December 1964; 93 (3): 652–665. doi: https://doi.org/10.1042/bj0930652 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search © 1964 The Biochemical Society1964 Article PDF first page preview Close Modal You do not currently have access to this content.

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  • Higher plasma lipid concentration drives fuel oxidation by increasing fat oxidation.

    “Just as intracellular glucose availability influences metabolic flexibility, higher plasma lipid concentration also drives fuel oxidation by increasing fat oxidation ([14](#r14), [33](#r33), [46](#r46), [52](#r52)).”

    From Metabolic flexibility and insulin resistance (2008) · cites this paper as [46]

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  1. Crane, R. K. & Sols, A. (1955). In Methods in Enzymology, vol. 1, p. 277. Ed. by Colowick, S. P. & Kaplan, N. 0. New York: Academic Press Inc.

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Authors
Randle, P., Newsholme, E., & Garland, P.
Affiliations
University of Cambridge (GB)
Venue
Biochemical Journal
Published
1964-12-01
Volume
93
Issue
3
Pages
652-665
ISSN
0006-2936 (ISSN-L)
OpenAlex
W1531062343
Cited by
736
References
27
Citations by year
2026: 2 · 2025: 9 · 2024: 7 · 2023: 7 · 2022: 12 · 2021: 9 · 2020: 1 · 2019: 3 · 2018: 14 · 2017: 13 · 2016: 11 · 2015: 11 · 2014: 7 · 2013: 6 · 2012: 7
FWCI
6.98
Type
journal article
Language
en
Open access
Locations
  • Biochemical Journal (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
  • Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
glucose uptake, muscle glucose metabolism, fatty acids, ketone bodies, pyruvate, alloxan-induced diabetes, starvation, myocardium, diaphragm
MeSH terms
Animals, Hypoxia, Arabinose, Carbon Dioxide, Diabetes Mellitus, Experimental, Diaphragm, Fatty Acids, Glucose, Glycogen, Glycolysis, Heart, Hydroxybutyrates, Muscles, Myocardium, Perfusion, Phosphofructokinase-1, Pyruvates, Salicylates, Starvation, Rats, In Vitro Techniques

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